Full professor
Department of Surgery
Faculty of Medicine

The research conducted by Dr. Fradet and his team covers a variety of aspects ranging from the analysis and modulation of lifestyle habits (e.g., diet, physical activity, etc.) for the prevention and control of cancer, to the analysis of the impact of the microbiota on cancer and its response to treatment. We also focus on the development of new prognostic approaches based on the discovery and evaluation of different biomarkers able to predict the evolution of cancers or their response to chemotherapy treatments, radiotherapy, and/or immunotherapy. Additionally, we work on the characterization of tumor antigens and the development of new immunotherapeutic approaches by methods combining immunology and molecular biology. Finally, we analyze the efficacy of new drugs or therapeutic modalities in clinical trials. The cancers targeted by our research are mainly urological cancers, particularly bladder and prostate cancers.

To carry out this research, it is essential to have access to quality biological samples and clinical data. An important part of our research is the development of biobanks of clinical samples and data to help researchers here and abroad advance knowledge of bladder and prostate cancers and their clinical management. Our group has participated in the establishment of different biobanks such as URO-1 and BIOCaPPE, as well as various tumor registries. The use of these biobanks and tumor registries has enabled local, national, and international collaborations that have led to important scientific advances.

For more information on past and current research, please refer to the Publications and Projects sections.