Mélanie Laurin
Chercheuse universitaire
Axe Oncologie
Publications
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article Hotea DI, Jetté A, Beaudin A, Lauzon M, Kalyanakrishnan K, Laurin M
FGD1 restrains actomyosin contractility to promote suprabasal junction maturation in stratified keratinocytes
J Cell Sci 2026.
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article Beaudin A, Lefrançois P, Laurin M
Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities
Biochem Soc Trans 54 (5), 2026.
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article Kalyanakrishnan K, Beaudin A, Jetté A, Ghezelbash S, Ioana Hotea D, Chen J, Lefrançois P, Laurin M
The Rho GTPase regulator ARHGEF3 orchestrates hair placode budding by coordinating cell fate and P-cadherin patterning in mice
PLoS Biol 24 (1), 2026.
Projects
- Deciphering the specificity and function of FGD RhoGEFs during skin development, from 2020-04-01 to 2028-03-31
- Unravelling the role of ARHGEF3 during skin development and hair follicle regeneration, from 2021-10-01 to 2026-09-30
- GMEB-SASS: The first clinical trial phase I/II using a genetically modified epidermolysis bullosa self-assembled skin substitute to treat dystrophic epidermolysis bullosa, a severe rare skin disease, from 2024-04-01 to 2028-03-31
- Optimization of a mouse xenograph platform to study BCC progression, from 2026-02-15 to 2027-02-14
- Deciphering the specificity and function of FGD RhoGEFs during skin development, from 2020-04-01 to 2025-03-31
- Étude des voies de signalisation régulant le développement embryonnaire et le cancer de la peau, from 2021-07-01 to 2025-06-30
- Étude des voies de signalisation régulant le développement embryonnaire et le cancer de la peau- Subvention d'établissement de jeune chercheuse, from 2021-07-01 to 2025-06-30
- Development of a in vivo mouse screening platform to identify molecular effectors of non-melanoma skin cancers, from 2022-12-01 to 2025-04-30
- Mise en place de la plateforme d'ingénierie tissulaire en cancer, from 2023-09-01 to 2025-12-31
- Efficient and reliable cryosectioning for the study of embryonic tissues development, from 2024-04-01 to 2025-03-31
- Identifying epithelial-to-mesenchymal transition effectors in aggressive basal cell carcinoma, from 2023-09-01 to 2025-08-31