Manu Rangachari
Chercheur universitaire
Axe Neurosciences
Publications
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article Gommerman JL, Akassoglou K, Baranzini SE, Becher B, Brilot F, Castelo-Branco G, Dunn SE, Faiz M, Flügel A, Ghasemlou N, Gibson EM, Greer JM, Gris D, Harrington CA, Jung S, Kalia LV, Korn T, Krishnamoorthy G, Liblau RS, Odoardi F, Piccio L, Pröbstel AK, Quintana FJ, Ramaglia V, Rangachari M, Rojas OL, Ruitenberg MJ, Russo S, Schafer DP, Segal BM, Vukovic J, Wang C, Wheeler MA, Wiendl H, Yong VW, Zipp F, Miron VE
Use of animal models to understand CNS neuroimmunology – guidance from the International Society for Neuroimmunology White Paper Task Force
Nat Rev Neurol 2026.
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article Falle A, Rangachari M
PKM2 works “off the books” to drive effector T cell function in MS
Sci Immunol 11 (122), 2026.
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article Akbar I, Arokia Doss PMI, Patel PU, Surury B, Baillargeon J, Fazazi MR, Anderson AC, Rojas OL, Lassmann H, Rangachari M
Myelin antigen-specific effector CD8+ T cells induce chronic CNS autoimmunity in a CD4+ T cell-dependent manner
J Immunol 215 (5), 2026.
Projects
- Sex chromosomes dictate Th17 cell pathogenicity in a model of progressive CNS autoimmunity, from 2020-07-01 to 2028-10-27
- Stressed to a T: The role of stress granule dynamics in regulating effector T cell function, from 2023-04-01 to 2028-03-31
- The interplay of sex hormones and chromosomes dictates pathogenicity in progressive CNS autoimmunity, from 2024-04-01 to 2029-03-31
- Oxidative phosphorylation drives B cell and Tph cell inflammatory responses within the CNS, from 2025-04-01 to 2028-03-31
- Oxidative phosphorylation drives neuroinflammatory B cell and Tph cell responses in progressive CNS autoimmunity, from 2025-04-01 to 2028-03-31
- Into the (re-) wild: moving beyond lab-raised mice in order to make EAE more reflective of human MS, from 2026-04-01 to 2028-03-31
- Cellular characterization of a novel putative immune biomarker of MS progression, from 2021-10-01 to 2026-09-30
- Élucidation des immunophénotypes cellulaires et moléculaires de la sclérose en plaques progressive sécondaire et ses modèles animaux, from 2022-07-01 to 2026-06-30
- endMS National Education and Training Program: Summer School and SPRINT, from 2023-06-15 to 2026-06-14
- Sins of the father: a parent of origin effect to explain pathogenic outcomes in progressive MS, from 2024-04-01 to 2025-03-31