Jean-Yves Masson
Chercheur universitaire
Axe Oncologie
Publications
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article Richardson ME, Bishop MFH, Holdren MA, de la Hoya M, Spurdle AB, Tavtigian SV, Brannan T, Young CC, Zec L, Hiraki S, Turnbull C, Tischkowitz M, Bernstein KA, Masson JY, McNulty SM, Pesaran T, Monteiro AN, Walker LC, Foulkes WD, Couch FJ
Specifications of the ACMG/AMP variant curation guidelines for the analysis of germline PALB2 sequence variants
Am J Hum Genet 113 (5), 2026.
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article Le BV, Vekariya U, Toma MM, Nieborowska-Skorska M, Caron MC, Gozdecka M, Haydar Z, Walsh M, Ghosh J, Vaughan-Williams E, Podszywalow-Bartnicka P, Kukuyan AM, Ziolkowska S, Atkins J, Hadzijusufovic E, Chandramouly G, Nejati R, Piwocka K, Pomerantz R, Vassiliou GS, Huntly BJP, Valent P, Wasik M, Bellacosa A, Masson JY, Gupta GP, Challen GA, Skorski T
Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia
Cell Rep Med 7 (3), 2026.
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article Cui S, Batenburg NL, Coulombe Y, Arumugam A, Walker JR, Sheida SV, Bielinsky AK, Wahl MC, Masson JY, Zhu XD
Ski2-like helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses
Cell Rep 45 (3), 2026.
Projects
- Emerging roles of Zinc Finger PAR-Interacting Proteins (ZIPPs) in DNA double-strand break (DSB) repair: implications in PARPi therapy, from 2024-04-01 to 2029-03-31
- Characterization of novel breast cancer susceptibility genes through large-scale targeted sequencing and functional assays., from 2024-04-01 to 2029-03-31
- Caractérisation de nouveaux gènes de susceptibilité au cancer du sein, from 2024-02-15 to 2027-03-31
- Roles of the tumor suppressor PALB2 at the intersection of DNA repair and synthetic lethal strategies in cancer, from 2024-10-01 to 2029-09-30
- Defining and targeting the eraser functions of Poly(ADP-ribose) Glycohydrolase (PARG) in PAR-DNA hybrids and DNA double-strand break repair, from 2025-07-01 to 2030-06-30
- Assays evaluating small molecule RAD51 inhibitors: the road to anti-RAD51 drugs to treat aggressive and drug-resistant breast cancer, from 2024-06-30 to 2026-12-31
- Defining the biological consequences of formaldehyde-induced DNA lesions, from 2025-04-01 to 2030-03-31
- Characterization of novel breast cancer susceptibility genes through large-scale targeted sequencing and functional assays, from 2025-04-01 to 2029-03-31
- Label-free analysis of biomolecular interactions with next-gen biolayer interferometry, from 2026-03-31 to 2027-03-31
- MOHCCN Centre Transition Award, from 2026-04-01 to 2026-09-30
- Réseau de recherche sur le cancer (RRCancer), from 2023-04-01 to 2026-03-31
- Tumor biobanking was supported by the Banque de tissus et de données en cancers solides of the Réseau de recherche sur le cancer (RRCancer)...The RRCancer is funded by the Oncopole...de l'Économie, de l'Innovation et de l'Énergie du Québec., from 2023-04-01 to 2026-03-31
- Unveiling the roles of Poly(ADP)ribose Glycohydrolase (PARG) in DNA repair and cancer, from 2024-09-01 to 2025-08-31