Dr. Eric Boilard, PhD, is a recipient of a CIHR award, Associate Professor in the Department of Microbiology and Immunology at the Laval University School of Medicine, and a researcher at the CHU de Québec Research Center. He is also a researcher with the Canadian National Transplant Research Program (CNTRP), where he is co-leader and consulting member of the international group Systemic Lupus Collaborating Clinics (SLICC).
He obtained his PhD in Microbiology and Immunology from Laval University (2003) and pursued postdoctoral trainings at the Université de Nice-Sophia-Antipolis (2003-2006) and at Harvard University at Brigham and Women’s Hospital (2006-2010). It was during his studies at Harvard that Dr. Boilard highlighted the role of platelets in rheumatoid arthritis (Boilard et al., Science 2010).
His research aims to better understand the pathogenesis of rheumatic diseases, and to improve the success of blood transplants and transfusions to develop new therapeutics and biomarkers. He investigates how platelets and the small extracellular vesicles they produce, called microparticles, contribute to the inflammatory responses in place in rheumatoid arthritis, lupus, and the cases of immune responses involved in transplant rejection and adverse reactions related to transfusions. He conducts clinical research with patients and mouse models of disease.
He is an internationally renowned scientist and lecturer recognized by his peers. He won the Radio-Canada Award for the greatest medical discovery of the year (2011 and 2013), the Radio-Canada and Le Soleil Award of the Scientist of the Year (2011), and is the recipient of the André Dupont Award for Quebec’s most prolific young researcher (2017). His work is in part funded by the CIHR Foundation Program (Platelets and their microparticles: versatile players of inflammation) and NSERC.
2705, boulevard Laurier
Canada G1V 4G2
- [ULaval Nouvelles] Arthrite et microbiote: des molécules d’origine bactérienne exacerberaient l’inflammation 2022-01-26
- [ULaval Nouvelles] COVID-19 et tempête de cytokines : le sang ne reflète pas ce qui se passe dans les poumons 2021-06-08
- [ULaval Nouvelles] Lupus: l’étau se resserre autour des plaquettes 2021-02-18
Megakaryocytes and platelets embrace diversity in face of adversityJournal Article
J Thromb Haemost, 2022.
Live imaging of platelets and neutrophils during antibody-mediated neurovascular thrombosisJournal Article
Blood Adv, 6 (12), 2022.
Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cellsJournal Article
Blood Adv, 6 (12), 2022.
Red blood cell-derived phosphatidylserine positive extracellular vesicles are associated with past thrombotic events in patients with systemic erythematous lupusJournal Article
Lupus Sci Med, 9 (1), 2022.
Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomesJournal Article
Cell Death Dis, 13 (2), 2022.
Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus ErythematosusJournal Article
Arthritis Rheumatol, 2022.
Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiotaJournal Article
JCI Insight, 7 (2), 2022.
The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammationJournal Article
JCI Insight, 7 (2), 2022.
Platelet extracellular vesicles in COVID-19: Potential markers and makersJournal Article
J Leukoc Biol, 111 (1), 2022.
Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor AxisJournal Article
Int J Mol Sci, 22 (23), 2021.
- Contribution of phospholipase A2 enzymes in the homeostasis of the immune system., from 2016-04-01 to 2023-03-31
- COVID-19 trilogy: ARDS, inflammation and coagulopathy, from 2020-06-01 to 2024-03-31
- Elucidating the role of the pro-inflammatory P2Y14 receptor in acute kidney injury, from 2022-04-01 to 2027-03-31
- Pathogenic roles of platelets in sepsis, from 2020-03-01 to 2025-03-31
- Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-04-01 to 2025-03-31
- Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-01-01 to 2022-12-31
- Rôle des plaquettes et de leurs microparticules dans l'inflammation, from 2019-08-01 to 2023-07-31
- Rôle des plaquettes et des vésicules extracellulaires dans l'inflammation, from 2022-01-01 to 2023-05-31
- Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., from 2015-07-01 to 2023-03-31
- The impact of antimalarial drugs in arthritis patients exposed to SARS-CoV-2- the CoVIRAL project, from 2020-04-01 to 2023-03-31
- Understanding the pathogenesis of COVID-19, from 2020-03-01 to 2024-03-31
Recently finished projects
- Computer-Aided Sperm Analysis (CASA) of sperm motility and hyperactivation, from 2021-04-01 to 2022-03-31
- Mapping anti-mitochondrial antibodies in systemic lupus erythematosus, from 2019-04-01 to 2022-03-31
- Pathogenesis and immune escape potential of SARS-CoV-2 variants of concern, from 2021-06-01 to 2022-05-31
- Platelets and their microparticles: versatile players of inflammation., from 2015-07-01 to 2020-06-30
- Profil moléculaire sanguin de patientes souffrant de lupus, from 2019-04-01 to 2021-03-31
- Role of antibodies in platelet response to SARS-CoV-2 and its variants, from 2021-06-01 to 2022-05-31
- Role of platelets and their mother cell, the megakaryocyte, in COVID-19, from 2021-03-01 to 2022-02-28
- The Canadian National Transplant Research Program : Increasing Donation and Improving Transplantation Outcomes, from 2013-04-01 to 2022-03-31