Dr. Éric Boilard, Ph.D., is Full Professor in the Department of Infectious Diseases and Immunity at the Faculty of Medicine at Université Laval, and a researcher at the Center de Recherche du CHU de Québec. He is also co-founder and co-director of the ARThrite Research Center (Arthrite-Research-Treatment) at Université Laval, Director of the Cytometry Platform of the Center de Recherche du CHU de Québec, and is a consulting member of the group International Systemic Lupus Collaborating Clinics (SLICC).

He obtained his doctorate in Microbiology and Immunology at Université Laval (2003) and pursued postdoctoral trainings at the Université de Nice-Sophia-Antipolis (2003-2006) and at Harvard University at the Brigham and Women’s Hospital (2006-2010). It was during his studies at Harvard that Dr. Boilard shed light on the role of platelets in rheumatoid arthritis (Boilard et al. Science 2010).

His work aims to better understand the pathogenesis of autoimmune diseases, notably rheumatic diseases, and to improve the development of new therapies through the development of biomarkers. He examines how platelets and the cells that produce them, called megakaryocytes, contribute to the inflammatory responses in place in rheumatoid arthritis, lupus, and cases of overwhelming inflammatory responses during microbial infections. For his work, he is also considering the extracellular vesicles produced by these cells using advanced technologies. He carries out his research in the clinic through the precious involvement of patients and with the help of mouse models of disease.

He is a renowned scientist and international lecturer recognized by his peers. He has won the Radio-Canada prize for the greatest medical discovery of the year on several occasions and the Radio-Canada and Le Soleil prize for scientist of the year. He is the recipient of the André Dupont prize awarded to the most prolific young Quebec researcher in clinical research and the Cozzarelli Prize awarded by the National Academy of Sciences (United States) in recognition of the excellence and originality of his work.

CHUL
2705, boulevard Laurier
T1-49
Québec, Québec
Canada G1V 4G2
+1 418-525-4444, extension 46175+1 418-654-2765
Eric.Boilard@crchudequebe...

Latest news

141 entries « ‹ 1 of 15 › »

Dussault S, Desjarlais M, Raguema N, Boilard E, Chemtob S, Rivard A

Selective Enrichment of Angiomirs in Extracellular Vesicles Released from Ischemic Skeletal Muscles: Potential Role in Angiogenesis and Neovascularization

Journal Article

Cells, 13 (15), 2024.

Abstract | Links:

Cleary SJ, Seo Y, Tian JJ, Kwaan N, Bulkley DP, Bentlage AE, Vidarsson G, Boilard É, Spirig R, Zimring JC, Looney MR

IgG hexamers initiate complement-dependent acute lung injury

Journal Article

J Clin Invest, 134 (11), 2024.

Abstract | Links:

Allaeys I, Lemaire G, Leclercq M, Lacasse E, Fleury M, Dubuc I, Gudimard L, Puhm F, Tilburg J, Stone A, Machlus KR, Droit A, Flamand L, Boilard E

SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow

Journal Article

Blood Adv, 8 (11), 2024.

Abstract | Links:

Neyrinck-Leglantier D, Tamagne M, Ben Rayana R, Many S, Vingert P, LeGagneux J, Delorme AS, Andrieu M, Boilard E, Cognasse F, Hamzeh-Cognasse H, Perez-Patrigeon S, Lelievre JD, Pirenne F, Gallien S, Vingert B

Immunoregulatory molecule expression on extracellular microvesicles in people living with HIV

Journal Article

Front Immunol, 15 , 2024.

Abstract | Links:

Carrier M, Robert MÈ, St-Pierre MK, Ibáñez FG, Gonçalves de Andrade E, Laroche A, Picard K, Vecchiarelli HA, Savage JC, Boilard É, Desjardins M, Tremblay MÈ

Bone marrow-derived myeloid cells transiently colonize the brain during postnatal development and interact with glutamatergic synapses

Journal Article

iScience, 27 (7), 2024.

Abstract | Links:

Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ, , Théry C, Witwer KW

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Journal Article

J Extracell Vesicles, 13 (2), 2024.

Abstract | Links:

Vachon L, Jean G, Milasan A, Babran S, Lacroix E, Guadarrama Bello D, Villeneuve L, Rak J, Nanci A, Mihalache-Avram T, Tardif JC, Finnerty V, Ruiz M, Boilard E, Tessier N, Martel C

Platelet extracellular vesicles preserve lymphatic endothelial cell integrity and enhance lymphatic vessel function

Journal Article

Commun Biol, 7 (1), 2024.

Abstract | Links:

Barrachina MN, Pernes G, Becker IC, Allaeys I, Hirsch TI, Groeneveld DJ, Khan AO, Freire D, Guo K, Carminita E, Morgan PK, Collins TJC, Mellett NA, Wei Z, Almazni I, Italiano JE, Luyendyk J, Meikle PJ, Puder M, Morgan NV, Boilard E, Murphy AJ, Machlus KR

Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36

Journal Article

Nat Cardiovasc Res, 2 (8), 2023.

Abstract | Links:

Lacasse É, Gudimard L, Dubuc I, Gravel A, Allaeys I, Boilard É, Flamand L

SARS-CoV-2 Nsp2 Contributes to Inflammation by Activating NF-κB

Journal Article

Viruses, 15 (2), 2023.

Abstract | Links:

Scherlinger M, Richez C, Tsokos GC, Boilard E, Blanco P

Author Correction: The role of platelets in immune-mediated inflammatory diseases

Journal Article

Nat Rev Immunol, 23 (6), 2023.

| Links:

141 entries « ‹ 1 of 15 › »
Signaler des ajouts ou des modifications

Active projects

  • Elucidating the role of the pro-inflammatory P2Y14 receptor in acute kidney injury, from 2022-04-01 to 2027-03-31
  • Étude du rôle des plaquettes et de leurs vésicules extra cellulaires dans l'inflammation, from 2024-07-01 to 2028-06-30
  • Étude du rôle des plaquettes et de leurs vésicules extra cellulaires dans l'inflammation, from 2024-07-01 to 2028-06-30
  • Pathogenesis and immune escape potential of SARS-CoV-2 variants of concern, from 2021-06-01 to 2025-03-31
  • Pathogenic roles of platelets in sepsis, from 2020-03-01 to 2025-03-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-04-01 to 2025-03-31
  • Role of megakaryocytes in Systemic Lupus Erythematosus, from 2023-04-01 to 2028-03-31
  • Role of the interaction of secretory phospholipase A2 enzymes and bacterial extracellular vesicles in the homeostasis of the immune system, from 2024-04-01 to 2029-03-31

Recently finished projects

  • Contribution of phospholipase A2 enzymes in the homeostasis of the immune system., from 2016-04-01 to 2024-03-31
  • COVID-19 trilogy: ARDS, inflammation and coagulopathy, from 2020-06-01 to 2024-03-31
  • Megakaryocyte: a new player in systemic lupus erythematosus, from 2022-09-01 to 2023-08-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-01-01 to 2022-12-31
  • Premier biomarqueur sanguin de la maladie de Parkinson : de la validation à la commercialisation, from 2022-09-14 to 2024-09-13
  • Rôle des microparticules issues du bourgeonnement cellulaire dans les comoribidités associées à l'infection par le VIH, from 2022-02-01 to 2024-01-31
  • Rôle des plaquettes et de leurs microparticules dans l'inflammation, from 2019-08-01 to 2023-07-31
  • Rôle des plaquettes et des vésicules extracellulaires dans l'inflammation, from 2022-01-01 to 2023-05-31
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., from 2015-07-01 to 2023-03-31
  • The impact of antimalarial drugs in arthritis patients exposed to SARS-CoV-2- the CoVIRAL project, from 2020-04-01 to 2023-03-31
  • Understanding the pathogenesis of COVID-19, from 2020-03-01 to 2023-02-28
Data provided by the Université Laval research projects registery