Dr. Iwona Rudkowska is an Assistant professor in the Department of Kinesiology at Laval University, and a researcher at the Endocrinology and Nephrology Unit of CHU de Québec Research Center. She completed her university studies in nutrition at McGill University before pursuing postdoctoral training in nutritional genomics at Laval University. Her unique training as a dietitian and researcher, has led her to become a respected young scientist in nutrigenomics, fatty acids, and metabolic health.

Using genomics for the development of personalized nutrition interventions for the prevention and management of type 2 diabetes

Type 2 diabetes is an important public health issue. Several nutritional approaches have already been put in place for the prevention and management of diabetes; nevertheless, a large interindividual variability was observed in response to these interventions. It is therefore essential to understand the genetic architecture of the disease in order to be able to predict the response of an individual to a nutritional therapy. Using the profiles generated by experimental methods such as genetics, transcriptomics and metabolomics, the primary goal of her research is to identify molecular markers of an individual at risk of developing diabetes. This knowledge will allow the development of nutritional interventions adapted to each individual, and thus more effective in the prevention and the management of diabetes.

CHUL
2705, boulevard Laurier
T-4-50
Québec, Québec
Canada G1V 4G2
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O'Connor S, Turcotte AF, Gagnon C, Rudkowska I

Increased Dairy Product Intake Modifies Plasma Glucose Concentrations and Glycated Hemoglobin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Journal Article

Adv Nutr, 10 (2), pp. 262-279, 2019, ISSN: 2161-8313.

Abstract | Links:

Vallee Marcotte B, Guenard F, Lemieux S, Couture P, Rudkowska I, Calder PC, Minihane AM, Vohl MC

Fine mapping of genome-wide association study signals to identify genetic markers of the plasma triglyceride response to an omega-3 fatty acid supplementation.

Journal Article

Am J Clin Nutr, 109 (1), pp. 176-185, 2019, ISSN: 0002-9165.

Abstract | Links:

O'Connor S, Rudkowska I

Dietary Fatty Acids and the Metabolic Syndrome: A Personalized Nutrition Approach.

Journal Article

Adv Food Nutr Res, 87 , pp. 43-146, 2019, ISSN: 1043-4526.

Abstract | Links:

de Toro-Martin J, Guenard F, Rudkowska I, Lemieux S, Couture P, Vohl MC

A common variant in ARHGEF10 alters delta-6 desaturase activity and influence susceptibility to hypertriglyceridemia.

Journal Article

J Clin Lipidol, 12 (2), pp. 311-320.e3, 2018, ISSN: 1933-2874.

Abstract | Links:

Mutch DM, Zulyniak MA, Rudkowska I, Tejero ME

Lifestyle Genomics: Addressing the Multifactorial Nature of Personalized Health.

Journal Article

Lifestyle Genom, 11 (1), pp. 1-8, 2018.

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Taschereau-Charron A, Bilodeau JF, Larose J, Greffard K, Berthiaume L, Audibert F, Fraser WD, Julien P, Rudkowska I

F2-isoprostanes and fatty acids profile in early pregnancy complicated by pre-existing diabetes.

Journal Article

Prostaglandins Leukot Essent Fatty Acids, 135 , pp. 115-120, 2018, ISSN: 0952-3278.

Abstract | Links:

Da Silva MS, Bilodeau JF, Julien P, Rudkowska I

Dietary fats and F2-isoprostanes: A review of the clinical evidence.

Journal Article

Crit Rev Food Sci Nutr, 57 (18), pp. 3929-3941, 2017, ISSN: 1040-8398.

Abstract | Links:

Vallee Marcotte B, Cormier H, Rudkowska I, Lemieux S, Couture P, Vohl MC

Polymorphisms in FFAR4 (GPR120) Gene Modulate Insulin Levels and Sensitivity after Fish Oil Supplementation.

Journal Article

J Pers Med, 7 (4), 2017.

Abstract | Links:

Da Silva MS, Bilodeau JF, Larose J, Greffard K, Julien P, Barbier O, Rudkowska I

Modulation of the biomarkers of inflammation and oxidative stress by ruminant trans fatty acids and dairy proteins in vascular endothelial cells (HUVEC).

Journal Article

Prostaglandins Leukot Essent Fatty Acids, 126 , pp. 64-71, 2017, ISSN: 0952-3278.

Abstract | Links:

O'Connor S, Chouinard-Castonguay S, Gagnon C, Rudkowska I

Prebiotics in the management of components of the metabolic syndrome.

Journal Article

Maturitas, 104 , pp. 11-18, 2017, ISSN: 0378-5122.

Abstract | Links:

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Active projects

  • Centre hospitalier universitaire de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Dairy bioactive nutrients synergistic effects against inflammation: nutrigenomics and metabolomics approaches., Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2022-03-31

Recently finished projects

  • Centre de recherche en endocrinologie, métabolisme et inflammation, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-06-01 to 2018-04-30
  • Nutrigenomic approach to investigate the benefits of dairy product consumption on glucose homeostasis, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2017-06-30
  • Utilisation de profils génomiques pour le développement d'interventions nutritionnelles personnalisées pour le diabète et les facteurs de risques associés, Subvention, Fonds de recherche du Québec - Santé, Établissement de jeunes chercheurs - Juniors 1, from 2014-07-01 to 2017-06-30
  • Utilisation de profils génomiques pour le développement d'interventions nutritionnelles personnalisées pour le diabète et les facteurs de risques associés., Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2014-07-01 to 2018-12-31
Data provided by the Université Laval research projects registery