Full professor
Department of Surgery
Faculty of Medicine

Dr. Vincent Fradet’s laboratory is particularly focused on the risk factors, prevention, and treatment of prostate and bladder cancer. His team studies the links between lifestyle—such as a diet rich in omega-3s—quality of life, inflammation, and oncogenic signaling pathways, with the goal of developing personalized prevention and treatment strategies.

His work combines clinical, epidemiological, and molecular research within a translational approach, aiming to identify and develop urinary, blood-based, epigenetic, molecular, and/or cellular biomarkers. He is especially interested in lifestyle habits and the gut microbiome as predictive markers and intervention targets in urological cancers.

Dr. Fradet has access to a large biobank of biological samples, as well as mouse models and primary cell cultures. The biobank (blood, urine, biopsies, stool) and preclinical models allow for the study of inflammatory, immune, hormonal, and proliferative mechanisms involved in tumor development and response to certain treatments, including immunotherapy. He also conducts clinical studies to examine the effects of various pharmaceutical and nutritional interventions (different types of omega-3s) on prostate cancer. In short, his research team is engaged in multiple areas of clinical and fundamental research with a translational focus.