52 enregistrements « ‹ 1 de 6 › »

Bordeleau F

Using Machine Learning to Predict TP53 Mutation Status and Aggressiveness of Prostate Cancer from Routine Histology Images

Article de revue

Cancer Res, 83 (17), 2023.

Résumé | Liens:

Wang W, Taufalele PV, Millet M, Homsy K, Smart K, Berestesky ED, Schunk CT, Rowe MM, Bordeleau F, Reinhart-King CA

Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA

Article de revue

Cell Rep, 42 (4), 2023.

Résumé | Liens:

Bordeleau F, Brownell D, Chabaud S, Huot ME, Bolduc S

Recreating heterogeneity of bladder cancer microenvironment to study its recurrences and progression

Article de revue

Stem Cell Investig, 10 , 2023.

| Liens:

Tang YC, Ponsin K, Graham-Paquin AL, Luthold C, Homsy K, Schindler M, Tran V, Côté JF, Bordeleau F, Khadra A, Bouchard M

Coordination of non-professional efferocytosis and actomyosin contractility during epithelial tissue morphogenesis

Article de revue

Cell Rep, 42 (3), 2023.

Résumé | Liens:

Taufalele PV, Wang W, Simmons AJ, Southard-Smith AN, Chen B, Greenlee JD, King MR, Lau KS, Hassane DC, Bordeleau F, Reinhart-King CA

Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment

Article de revue

Acta Biomater, 163 , 2023.

Résumé | Liens:

Piquet L, Coutant K, Mitchell A, Ben Anes A, Bollmann E, Schoonjans N, Bérubé J, Bordeleau F, Brisson A, Landreville S

Extracellular Vesicles from Ocular Melanoma Have Pro-Fibrotic and Pro-Angiogenic Properties on the Tumor Microenvironment

Article de revue

Cells, 11 (23), 2022.

Résumé | Liens:

Schwager SC, Young KM, Hapach LA, Carlson CM, Mosier JA, McArdle TJ, Wang W, Schunk C, Jayathilake AL, Bates ME, Bordeleau F, Antonyak MA, Cerione RA, Reinhart-King CA

Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis

Article de revue

Elife, 11 , 2022.

Résumé | Liens:

Millet M, Bollmann E, Ringuette Goulet C, Bernard G, Chabaud S, Huot MÉ, Pouliot F, Bolduc S, Bordeleau F

Cancer-Associated Fibroblasts in a 3D Engineered Tissue Model Induce Tumor-like Matrix Stiffening and EMT Transition

Article de revue

Cancers (Basel), 14 (15), 2022.

Résumé | Liens:

Luthold C, Hallal T, Labbé DP, Bordeleau F

The Extracellular Matrix Stiffening: A Trigger of Prostate Cancer Progression and Castration Resistance?

Article de revue

Cancers (Basel), 14 (12), 2022.

Résumé | Liens:

Hapach LA, Carey SP, Schwager SC, Taufalele PV, Wang W, Mosier JA, Ortiz-Otero N, McArdle TJ, Goldblatt ZE, Lampi MC, Bordeleau F, Marshall JR, Richardson IM, Li J, King MR, Reinhart-King CA

Phenotypic Heterogeneity and Metastasis of Breast Cancer Cells

Article de revue

Cancer Res, 81 (13), 2021.

Résumé | Liens:

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Projets actifs

  • Canada Research Chair in Tumor Mechanoregulation, du 2020-07-01 au 2025-06-30
  • Hepatic stellate cells as a driver of the pre-metastatic niche in uveal melanoma, du 2023-03-01 au 2024-02-29
  • Programme de soutien aux nouveaux détenteurs de CRC, du 2022-05-01 au 2024-04-30
  • Protein glycation acts as a substrate-dependent tumorigenic molecular switch in prostate cancer, du 2022-04-01 au 2027-03-31
  • The combined role of cellular force dynamics and extracellular matrix mechanical properties in driving angiogenesis, du 2018-04-01 au 2024-03-31

Projets terminés récemment

  • Bourse Concert pour la vie , du 2020-11-13 au 2021-11-12
  • Exploration of a novel therapeutic strategy impeding triple-negative breast cancer growth and progression, du 2022-04-01 au 2023-03-31
  • Mécanobiologie du cancer: rôle intégrateur de la contractilité cellulaire sur le potentiel métastatique cellulaire, du 2018-07-01 au 2022-06-30
  • Role of sugar-dependent extracellular matrix stiffening in driving prostate cancer metastasis, du 2019-03-29 au 2022-03-28
  • Subvention interdisciplinaire du CRC, du 2020-04-01 au 2022-03-31
  • Thérapie photodynamique véctorisée du cancer de la vessie: étude sur un modèle 3D reconstruit par génie tissulaire, du 2021-04-01 au 2023-03-31
  • Toward elucidating the interplay between cell contractility state, mechanotransduction and alternative splicing during tumor progression, du 2022-03-01 au 2023-02-28
  • Tumor Mechanobiology Research Platform, du 2019-04-01 au 2021-09-30
Information provenant du registre des projets de recherche de l'Université Laval