David Gosselin
Chercheur universitaire
Axe Neurosciences
Dernières nouvelles
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Publications
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article Fixsen BR, Han CZ, Zhou Y, Spann NJ, Saisan P, Shen Z, Balak C, Sakai M, Cobo I, Holtman IR, Warden AS, Ramirez G, Collier JG, Pasillas MP, Yu M, Hu R, Li B, Belhocine S, Gosselin D, Coufal NG, Ren B, Glass CK
SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity
Nat Immunol 24 (7), 2023.
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article Chignon A, Rosa M, Boulanger MC, Argaud D, Devillers R, Bon-Baret V, Mkannez G, Li Z, Rufiange A, Gaudreault N, Gosselin D, Thériault S, Bossé Y, Mathieu P
Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis
iScience 24 (3), 2021.
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article Mishra MK, Rawji KS, Keough MB, Kappen J, Dowlatabadi R, Vogel HJ, Chopra S, Distéfano-Gagné F, Dufour A, Gosselin D, Yong VW
Harnessing the Benefits of Neuroinflammation: Generation of Macrophages/Microglia with Prominent Remyelinating Properties
J Neurosci 41 (15), 2021.
Projets
- Delineation of the epigenomic principles underlying microglial transcriptional and cellular activity in chronic neurodegenerative diseases, du 2020-03-01 au 2025-03-31
- Understanding and rejuvenating microglial phagocytosis as mean to inhibit progression of tauopathies in a mouse model of Alzheimer’s Disease, du 2020-10-01 au 2025-09-30
- Delineation of the epigenomic principles underlying microglial transcriptional and cellular activity in demyelinating brain disorders, du 2021-04-01 au 2026-03-31
- Étude des mécanismes de la régulation épigénétique et transcriptionelle responsables des fonctions des microglies dans le, du 2023-07-01 au 2025-06-30
- Enhancing microglial myelin repair mechanisms through stimulation of the Ppar-delta nuclear receptor as a novel therapeutic approach for multiple sclerosis, du 2020-09-01 au 2024-08-31
- Étude des mécanismes de la régulation épigénétique et transcriptionnelle responsable des fonctions des microglies, du 2022-01-01 au 2024-08-31