39 enregistrements « 1 de 4 »

Arbour G, Ellezam B, Weil AG, Cayrol R, Vanan MI, Coltin H, Larouche V, Erker C, Jabado N, Perreault S

Upfront BRAF/MEK inhibitors for treatment of high-grade glioma: A case report and review of the literature

Article de revue

Neurooncol Adv, 4 (1), 2022.

Résumé | Liens:

Erker C, Mynarek M, Bailey S, Mazewski CM, Baroni L, Massimino M, Hukin J, Aguilera D, Cappellano AM, Ramaswamy V, Lassaletta A, Perreault S, Kline CN, Rajagopal R, Michaiel G, Zapotocky M, Santa-Maria Lopez V, La Madrid AM, Cacciotti C, Sandler ES, Hoffman LM, Klawinski D, Khan S, Salloum R, Hoppmann AL, Larouche V, Dorris K, Toledano H, Gilheeney SW, Abdelbaki MS, Wilson B, Tsang DS, Knipstein J, Oren MY, Shah S, Murray JC, Ginn KF, Wang ZJ, Fleischhack G, Obrecht D, Tonn S, Harrod VL, Matheson K, Crooks B, Strother DR, Cohen KJ, Hansford JR, Mueller S, Margol A, Gajjar A, Dhall G, Finlay JL, Northcott PA, Rutkowski S, Clifford SC, Robinson G, Bouffet E, Lafay-Cousin L

Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study

Article de revue

J Clin Oncol, 2022.

Résumé | Liens:

Jessa S, Mohammadnia A, Harutyunyan AS, Hulswit M, Varadharajan S, Lakkis H, Kabir N, Bashardanesh Z, Hébert S, Faury D, Vladoiu MC, Worme S, Coutelier M, Krug B, Faria Andrade A, Pathania M, Bajic A, Weil AG, Ellezam B, Atkinson J, Dudley RWR, Farmer JP, Perreault S, Garcia BA, Larouche V, Blanchette M, Garzia L, Bhaduri A, Ligon KL, Bandopadhayay P, Taylor MD, Mack SC, Jabado N, Kleinman CL

K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas

Article de revue

Nat Genet, 54 (12), 2022.

Résumé | Liens:

Gourmel A, Rouette A, Benlimame N, El-Jalbout R, Dubé M, Théorêt Y, Piché N, Labonté S, Sinnett D, Cellot S, Dal-Soglio D, Larouche V, Tran TH

Durable Response to Trametinib in an Infant With ERC1-BRAF Infantile Fibrosarcoma-Like Tumor: A Case Report and Literature Review of BRAF-Altered Infantile Fibrosarcoma-Like Tumors

Article de revue

JCO Precis Oncol, 6 , 2022.

| Liens:

Coltin H, Perreault S, Larouche V, Black K, Wilson B, Vanan MI, Gupta AA, Morgenstern DA, Parkin PC, Bouffet E, Ramaswamy V

Selumetinib for symptomatic, inoperable plexiform neurofibromas in children with neurofibromatosis type 1: A national real-world case series

Article de revue

Pediatr Blood Cancer, 69 (8), 2022.

Résumé | Liens:

Das A, Sudhaman S, Morgenstern D, Coblentz A, Chung J, Stone SC, Alsafwani N, Liu ZA, Karsaneh OAA, Soleimani S, Ladany H, Chen D, Zatzman M, Cabric V, Nobre L, Bianchi V, Edwards M, Sambira Nahum LC, Ercan AB, Nabbi A, Constantini S, Dvir R, Yalon-Oren M, Campino GA, Caspi S, Larouche V, Reddy A, Osborn M, Mason G, Lindhorst S, Bronsema A, Magimairajan V, Opocher E, De Mola RL, Sabel M, Frojd C, Sumerauer D, Samuel D, Cole K, Chiaravalli S, Massimino M, Tomboc P, Ziegler DS, George B, Van Damme A, Hijiya N, Gass D, McGee RB, Mordechai O, Bowers DC, Laetsch TW, Lossos A, Blumenthal DT, Sarosiek T, Yen LY, Knipstein J, Bendel A, Hoffman LM, Luna-Fineman S, Zimmermann S, Scheers I, Nichols KE, Zapotocky M, Hansford JR, Maris JM, Dirks P, Taylor MD, Kulkarni AV, Shroff M, Tsang DS, Villani A, Xu W, Aronson M, Durno C, Shlien A, Malkin D, Getz G, Maruvka YE, Ohashi PS, Hawkins C, Pugh TJ, Bouffet E, Tabori U

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

Article de revue

Nat Med, 28 (1), 2022.

Résumé | Liens:

Pelland-Marcotte MC, Xie L, Barber R, Elkhalifa S, Frechette M, Kaur J, Onysko J, Bouffet E, Fernandez CV, Mitchell D, Rayar M, Randall A, Stammers D, Larouche V, Airhart A, Fidler-Benaoudia M, Cohen-Gogo S, Sung L, Gibson P

Incidence of childhood cancer in Canada during the COVID-19 pandemic

Article de revue

CMAJ, 193 (47), 2021.

Résumé | Liens:

Goudie C, Witkowski L, Cullinan N, Reichman L, Schiller I, Tachdjian M, Armstrong L, Blood KA, Brossard J, Brunga L, Cacciotti C, Caswell K, Cellot S, Clark ME, Clinton C, Coltin H, Felton K, Fernandez CV, Fleming AJ, Fuentes-Bolanos N, Gibson P, Grant R, Hammad R, Harrison LW, Irwin MS, Johnston DL, Kane S, Lafay-Cousin L, Lara-Corrales I, Larouche V, Mathews N, Meyn MS, Michaeli O, Perrier R, Pike M, Punnett A, Ramaswamy V, Say J, Somers G, Tabori U, Thibodeau ML, Toupin AK, Tucker KM, van Engelen K, Vairy S, Waespe N, Warby M, Wasserman JD, Whitlock JA, Sinnett D, Jabado N, Nathan PC, Shlien A, Kamihara J, Deyell RJ, Ziegler DS, Nichols KE, Dendukuri N, Malkin D, Villani A, Foulkes WD

Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes

Article de revue

JAMA Oncol, 7 (12), 2021.

Résumé | Liens:

Chung J, Maruvka YE, Sudhaman S, Kelly J, Haradhvala NJ, Bianchi V, Edwards M, Forster VJ, Nunes NM, Galati MA, Komosa M, Deshmukh S, Cabric V, Davidson S, Zatzman M, Light N, Hayes R, Brunga L, Anderson ND, Ho B, Hodel KP, Siddaway R, Morrissy AS, Bowers DC, Larouche V, Bronsema A, Osborn M, Cole KA, Opocher E, Mason G, Thomas GA, George B, Ziegler DS, Lindhorst S, Vanan M, Yalon-Oren M, Reddy AT, Massimino M, Tomboc P, Van Damme A, Lossos A, Durno C, Aronson M, Morgenstern DA, Bouffet E, Huang A, Taylor MD, Villani A, Malkin D, Hawkins CE, Pursell ZF, Shlien A, Kunkel TA, Getz G, Tabori U

DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells

Article de revue

Cancer Discov, 11 (5), 2021.

Résumé | Liens:

Larouche V, Bellavance C, Tibout P, Bergeron S, Simonyan D, Gagné J

Screening for asymptomatic diabetes and metabolic comorbidities in pediatric patients during therapy for acute lymphoblastic leukemia

Article de revue

J Pediatr Endocrinol Metab, 34 (5), 2021.

Résumé | Liens:

39 enregistrements « 1 de 4 »
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Projets actifs

  • A Phase 2 study of Trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathwa, du 2019-04-01 au 2024-09-30
  • Phase III randomized double-blind placebo-controlled trial of metformin for cognitive recovery and white matter growth in paediatric medulloblastoma patients, du 2022-06-21 au 2027-12-25

Projets terminés récemment

  • Étude de phase II - Thérapie ciblée pour le gliome de bas grade réfractaire et le neurofibrome plexiforme, du 2018-04-01 au 2021-03-31
  • Subvention pour la recherche clinique, du 2008-04-01 au 2022-03-31
Information provenant du registre des projets de recherche de l'Université Laval