141 enregistrements « 2 de 15 »

Audet-Walsh E, Lin SX, Wang XQ

Using Omics to better understand steroid biosynthesis, metabolism, and functions

Article de revue

J Steroid Biochem Mol Biol, 202 , 2020.

| Liens:

Liu WJ, Zhao G, Zhang CY, Yang CQ, Zeng XB, Li J, Zhu K, Zhao SQ, Lu HM, Yin DC, Lin SX

Comparison of the roles of estrogens and androgens in breast cancer and prostate cancer

Article de revue

J Cell Biochem, 121 (4), 2020.

Résumé | Liens:

Sang X, Han H, Li T, Lin SX

Mutual regulations and breast cancer cell control by steroidogenic enzymes: Dual sex-hormone receptor modulation upon 17β-HSD7 inhibition

Article de revue

J Steroid Biochem Mol Biol, 193 , 2019.

Résumé | Liens:

Li T, Stephen P, Zhu DW, Shi R, Lin SX

Crystal structures of human 17β-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP reveal the mechanism of substrate inhibition

Article de revue

FEBS J, 286 (11), 2019.

Résumé | Liens:

Theriault JF, Lin SX

The dual sex hormone specificity for human reductive 17β-hydroxysteroid dehydrogenase type 7: Synergistic function in estrogen and androgen control

Article de revue

J Steroid Biochem Mol Biol, 186 , 2019.

Résumé | Liens:

Tchernof A, Lin SX, Luu-The V, Simard J

The Passing of Dr. Fernand Labrie (1937-2019): The legacy of excellence in science

Article de revue

J Steroid Biochem Mol Biol, 189 , 2019.

| Liens:

Li T, Zhang W, Hao J, Sun M, Lin SX

Cold-active extracellular lipase: Expression in Sf9 insect cells, purification, and catalysis

Article de revue

Biotechnol Rep (Amst), 21 , 2019.

Résumé | Liens:

Zhang CY, Calvo EL, Yang CQ, Liu J, Sang XY, Lin SX

Transcriptome of 17β-hydroxysteroid dehydrogenase type 2 plays both hormone-dependent and hormone-independent roles in MCF-7 breast cancer cells

Article de revue

J Steroid Biochem Mol Biol, 195 , 2019.

Résumé | Liens:

Ran Q, Xiang Y, Stephen P, Wu C, Li T, Lin SX, Li Z

CRIF1-CDK2 Interface Inhibitors: An Unprecedented Strategy for Modulation of Cell Radiosensitivity

Article de revue

J Am Chem Soc, 141 (4), 2019.

Résumé | Liens:

Stephen P, Lin SX

RNA-dependent RNA polymerase: Addressing Zika outbreak by a phylogeny-based drug target study

Article de revue

Chem Biol Drug Des, 91 (1), 2018.

Résumé | Liens:

141 enregistrements « 2 de 15 »
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Projets actifs

  • Pre-clinical pharmacokinetic and efficacy assays with an efficient 17beta-hydroxysteroid dehydrogenase type 7 inhibitor for breast cancer therapy, du 2024-03-01 au 2025-02-28

Projets terminés récemment

  • 3alpha-hydroxysteroid dehydrogenase type 3 as a modulator of human adipose tissue function and distribution, du 2020-04-01 au 2024-03-31
  • Innovative therapeutic approaches for the 2019-novel coronavirus, du 2021-03-01 au 2024-03-31
Information provenant du registre des projets de recherche de l'Université Laval