142 enregistrements « ‹ 1 de 15 › »

Sancéau JY, Maltais R, Zhou M, Lin SX, Poirier D

Synthesis and characterization of targeted 17β-hydroxysteroid dehydrogenase type 7 inhibitors

Article de revue

J Steroid Biochem Mol Biol, 242 , 2024.

Résumé | Liens:

Iqbal S, Lin SX

Deep Drug Discovery of Mac Domain of SARS-CoV-2 (WT) Spike Inhibitors: Using Experimental ACE2 Inhibition TR-FRET Assay, Screening, Molecular Dynamic Simulations and Free Energy Calculations

Article de revue

Bioengineering (Basel), 10 (8), 2023.

Résumé | Liens:

Zhang W, Lin SX

Search of Novel Small Molecule Inhibitors for the Main Protease of SARS-CoV-2

Article de revue

Viruses, 15 (2), 2023.

Résumé | Liens:

Li T, Song X, Stephen P, Yin H, Lin SX

New insights into the substrate inhibition of human 17β-hydroxysteroid dehydrogenase type 1

Article de revue

J Steroid Biochem Mol Biol, 228 , 2023.

Résumé | Liens:

Sang X, Belmessabih N, Wang R, Stephen P, Lin SX

CRIF1-CDK2 Interface Inhibitors Enhance Taxol Inhibition of the Lethal Triple-Negative Breast Cancer

Article de revue

Cancers (Basel), 14 (4), 2022.

Résumé | Liens:

Thériault JF, Poirier D, Lin SX

The multi-specific human 17 beta-hydroxysteroid dehydrogenase type 7: Non-competitive inhibitors can target different catalyses to facilitate breast cancer treatment

Article de revue

J Steroid Biochem Mol Biol, 214 , 2021.

Résumé | Liens:

Wang R, Stephen P, Tao Y, Zhang W, Lin SX

Human endeavor for anti-SARS-CoV-2 pharmacotherapy: A major strategy to fight the pandemic

Article de revue

Biomed Pharmacother, 137 , 2021.

Résumé | Liens:

Wang R, Li T, Li G, Lin SX

An unprecedented endocrine target for ovarian cancer: inhibiting 17β-HSD7 supresses cancer cell proliferation and arrests G2/M cycle

Article de revue

Am J Cancer Res, 11 (11), 2021.

Résumé | Liens:

Liu WJ, Zhao G, Zhang CY, Yang CQ, Zeng XB, Li J, Zhu K, Zhao SQ, Lu HM, Yin DC, Lin SX

Comparison of the roles of estrogens and androgens in breast cancer and prostate cancer

Article de revue

J Cell Biochem, 121 (4), 2020.

Résumé | Liens:

Li T, Zhang W, Lin SX

Steroid enzyme and receptor expression and regulations in breast tumor samples - A statistical evaluation of public data

Article de revue

J Steroid Biochem Mol Biol, 196 , 2020.

Résumé | Liens:

142 enregistrements « ‹ 1 de 15 › »
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Projets actifs

  • Pre-clinical pharmacokinetic and efficacy assays with an efficient 17beta-hydroxysteroid dehydrogenase type 7 inhibitor for breast cancer therapy, du 2024-03-01 au 2025-02-28

Projets terminés récemment

  • 3alpha-hydroxysteroid dehydrogenase type 3 as a modulator of human adipose tissue function and distribution, du 2020-04-01 au 2024-03-31
  • Innovative therapeutic approaches for the 2019-novel coronavirus, du 2021-03-01 au 2024-03-31
Information provenant du registre des projets de recherche de l'Université Laval