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Publications scientifiques

  • article Alpaugh M, Lantero-Rodriguez J, Benedet AL, Manseau U, Boutin M, Maiuri M, Denis HL, Masnata M, Fazal SV, Chouinard S, Rosa-Neto P, Barker RA, Blennow K, Zetterberg H, Labib R, Cicchetti F

    Tau levels in platelets isolated from Huntington’s disease patients serve as a biomarker of disease severity

    J Neurol 272 (3), 2025.

    DOI PUBMED
  • article Tan K, Alpaugh M, Ashton NJ, Chouinard S, Barker RA, Blennow K, Zetterberg H, Cicchetti F, Benedet AL

    Plasma GFAP and its association with disease severity in Huntington’s disease

    J Neurol 271 (4), 2024.

    DOI PUBMED
  • article Salem S, Alpaugh M, Saint-Pierre M, Alves-Martins-Borba FN, Cerquera-Cleves C, Lemieux M, Ngonza-Nito SB, De Koninck P, Melki R, Cicchetti F

    Treatment with Tau fibrils impact Huntington’s disease-related phenotypes in cell and mouse models

    Neurobiol Dis 202 2024.

    DOI PUBMED
  • article Salem S, Kilgore MD, Anwer M, Maxan A, Child D, Bird TD, Keene CD, Cicchetti F, Latimer C

    Evidence of mutant huntingtin and tau-related pathology within neuronal grafts in Huntington’s disease cases

    Neurobiol Dis 198 2024.

    DOI PUBMED
  • article Lepinay E, Cicchetti F

    Tau: a biomarker of Huntington’s disease

    Mol Psychiatry 28 (10), 2023.

    DOI PUBMED
  • article Denis HL, Alpaugh M, Alvarez CP, Fenyi A, Barker RA, Chouinard S, Arrowsmith CH, Melki R, Labib R, Harding RJ, Cicchetti F

    Detection of antibodies against the huntingtin protein in human plasma

    Cell Mol Life Sci 80 (2), 2023.

    DOI PUBMED
  • article Salem S, Cicchetti F

    Untangling the Role of Tau in Huntington’s Disease Pathology

    J Huntingtons Dis 12 (1), 2023.

    DOI PUBMED
  • article Alpaugh M, Denis HL, Cicchetti F

    Prion-like properties of the mutant huntingtin protein in living organisms: the evidence and the relevance

    Mol Psychiatry 27 (1), 2022.

    DOI PUBMED
  • article Alpaugh M, Cicchetti F

    Huntington’s disease: lessons from prion disorders

    J Neurol 268 (9), 2021.

    DOI PUBMED
  • article Pereira Luppi M, Azcorra M, Caronia-Brown G, Poulin JF, Gaertner Z, Gatica S, Moreno-Ramos OA, Nouri N, Dubois M, Ma YC, Ramakrishnan C, Fenno L, Kim YS, Deisseroth K, Cicchetti F, Dombeck DA, Awatramani R

    Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins

    Cell Rep 37 (6), 2021.

    DOI PUBMED
  • article Siddu A, David LS, Lauinger N, Chen X, Saint-Pierre M, Alpaugh M, Durcan T, Cicchetti F

    Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication

    Neurobiol Dis 145 2020.

    DOI PUBMED
  • article Alpaugh M, Cicchetti F

    A brief history of antibody-based therapy

    Neurobiol Dis 130 2019.

    DOI PUBMED