Dr. De Serres received his MD from University of Montreal and FRCPC in Internal Medicine and Nephrology following residency at Laval University in Canada. He then completed a 3-year Research Fellowship in transplant immunology at the Brigham and Women’s Hospital and received a Master of Epidemiology from Harvard School of Public Health. He is currently Associate Professor of Medicine at Laval University and Clinician-Scientist Junior II FRQS scholar.

At the national level, he has served as Chair of the 2018 Canadian Society of Transplantation Scientific Committee, in charge of organizing the Canadian Transplant Summit. At the international level, he has been elected as Executive Member of American Society of Transplantation Transplant Diagnostic Committee for a 2-year term, from 2016 to 2018. He also served as a member of the AST Transplantation and Immunology Research Network Scientific Committee from 2015 to 2018.

His research program focuses on cell-based assays to identify over-immunosuppression and on the mechanisms of antibody-mediated rejection. Since 2011, he has received continuous funding from different agencies including Kidney Foundation of Canada, CIHR, CFI and FRQS. His lab is currently funded by a CIHR Project Scheme grant and he is co-investigator and collaborator on several multicenter projects, including the CIHR-funded TMCT-04 trial and the Genome Canada-funded Can PREVENT AMR study.

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2879
Québec, Québec
Canada G1R 2J6
71 entries « 1 of 8 »

Désy O, Béland S, Thivierge MP, Marcoux M, Desgagnés JS, Bouchard-Boivin F, Gama A, Riopel J, Latulippe E, De Serres SA

T follicular helper cells expansion in transplant recipients correlates with graft infiltration and adverse outcomes

Journal Article

Front Immunol, 15 , 2024.

Abstract | Links:

De Serres SA, Couzi L

[The highlights of kidney transplantation in 2023]

Journal Article

Nephrol Ther, 20 (S1), 2024.

Abstract | Links:

Yi TW, Smyth B, Di Tanna GL, Arnott C, Cardoza K, Kang A, Pollock C, Agarwal R, Bakris G, Charytan DM, de Zeeuw D, Heerspink HJL, Neal B, Wheeler DC, Cannon CP, Zhang H, Zinman B, Perkovic V, Levin A, Mahaffey KW, Jardine M,

Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial

Journal Article

Am J Kidney Dis, 82 (1), 2023, ISSN: 1523-6838.

Abstract | Links:

Halawi A, El Kurdi AB, Vernon KA, Solhjou Z, Choi JY, Saad AJ, Younis NK, Elfekih R, Mohammed MT, Deban CA, Weins A, Abdi R, Riella LV, De Serres SA, Cravedi P, Greka A, Khoueiry P, Azzi JR

Uncovering a novel role of focal adhesion and interferon-gamma in cellular rejection of kidney allografts at single cell resolution

Journal Article

Front Immunol, 14 , 2023, ISSN: 1664-3224.

Abstract | Links:

Béland S, Désy O, El Fekih R, Marcoux M, Thivierge MP, Desgagné JS, Latulippe E, Riopel J, Wagner E, Rennke HG, Weins A, Yeung M, Lapointe I, Azzi J, De Serres SA

Expression of Class II Human Leukocyte Antigens on Human Endothelial Cells Shows High Interindividual and Intersubclass Heterogeneity

Journal Article

J Am Soc Nephrol, 34 (5), 2023.

Abstract | Links:

Ho J, Schaub S, Jackson AM, Balshaw R, Carroll R, Cun S, De Serres SA, Fantus D, Handschin J, Hönger G, Jevnikar AM, Kleiser M, Lee JH, Li Y, Nickerson P, Pei R, Pochinco D, Shih R, Trinh M, Wang J, Nguyen J, Knechtle S

Multicenter Validation of a Urine CXCL10 Assay for Noninvasive Monitoring of Renal Transplants

Journal Article

Transplantation, 107 (7), 2023.

Abstract | Links:

Kabbani D, Yotis DM, Ferreira VH, Shalhoub S, Belga S, Tyagi V, Ierullo M, Kulasingam V, Hébert MJ, West L, Delisle JS, Racine N, De Serres SA, Cardinal H, Dieudé M, Humar A, Kumar D

Immunogenicity, Safety, and Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infections After Coronavirus Disease 2019 Vaccination in Organ Transplant Recipients: A Prospective Multicenter Canadian Study

Journal Article

Open Forum Infect Dis, 10 (5), 2023.

Abstract | Links:

Desgagnés JS, Désy O, Thivierge MP, Marcoux M, Béland S, De Serres SA

SARS-Cov-2 Antibody Levels That Confer Immune Protection Based on Neutralization of the Omicron Variant

Journal Article

Transplantation, 107 (6), 2023.

| Links:

Hall VG, Al-Alahmadi G, Solera JT, Marinelli T, Cardinal H, Prasad GVR, De Serres SA, Isaac D, Mainra R, Lamarche C, Sapir-Pichhadze R, Gilmour S, Matelski J, Humar A, Kumar D

Outcomes of SARS-CoV-2 Infection in Unvaccinated Compared With Vaccinated Solid Organ Transplant Recipients: A Propensity Matched Cohort Study

Journal Article

Transplantation, 106 (8), 2022.

Abstract | Links:

Hildebrand AM, Barua M, Barbour SJ, Tennankore KK, Cattran DC, Takano T, Lam P, De Serres SA, Samanta R, Hladunewich MA, Fairhead T, Poyah P, Bush DD, MacLaren B, Sparkes D, Boll P, Jauhal A, John R, Avila-Casado C, Reich HN

The Canadian Glomerulonephritis Registry (CGNR) and Translational Research Initiative: Rationale and Clinical Research Protocol

Journal Article

Can J Kidney Health Dis, 9 , 2022.

Abstract | Links:

71 entries « 1 of 8 »
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Active projects

  • Addressing Critical Issues and Emerging TheRapEutics in TrAnsplanTation for COVID-19 - The TREAT-COVID Study , from 2024-03-07 to 2026-03-30
  • Arterial stiffness gradient as a new index of vascular aging: impact of blood pressure lowering medication, from 2019-10-01 to 2024-09-30
  • Chaire de recherche en néphrologie AMGEN, from 2019-01-01 to 2024-04-30
  • Mieux comprendre la réponse allo-immunitaire chez le greffé rénal afin de personnaliser l'immunothérapie, from 2020-07-01 to 2024-06-30
  • Rôle des cellules dendritiques dans l'immunologie de la transplantation., from 2015-01-01 to 2025-08-31

Recently finished projects

  • A cell-based assay to measure immune competence in SARS-CoV-2 infection and vaccination, from 2021-06-01 to 2022-05-31
  • Aldosterone antagonism and enhanced Clearance for Health Improvement EValuation in End-stage renal disease (ACHIEVE) Trial, from 2016-07-01 to 2022-06-30
  • Development and validation of a cell-based assay to identify over-immunosuppression in kidney transplant recipients, from 2019-10-01 to 2023-09-30
  • Mieux comprendre les mécanismes immunologiques du rejet chronique chez le greffé rénal afin d'améliorer le diagnostic et la prise en charge thérapeutique, from 2018-07-01 to 2022-06-30
Data provided by the Université Laval research projects registery