Dr. Robert Faure Ph.D.’s group is located at the Research Center of CHU Quebec, CHUL Centre-Mère-Enfant-Soleil. He is a full professor in the Department of Pediatrics of the Faculty of Medicine at Laval University.

Dr Faure studied the spatial and temporal insulin receptor signaling. He recently established a proteome of endosomes that allowed the study of physical protein interaction networks in a type 2 diabetes mellitus background. The resulting interactome is dense, organized around major hubs and highly enriched with genes associated with the type 2 diabetes genetic risk, defining a type 2 diabetes disease module. This module is formed by new signaling mechanisms that are largely unrelated to canonical insulin signaling pathways. It represents a valuable new resource that provides a mechanistic rationale for the exploration of personalized medicine and necessary drugs.

CHUL
2705, boulevard Laurier
T3-67
Québec, Québec
Canada G1V 4G2
+1 418-525-4444, extension 48263+1 418-654-2783
robert.faure@crchudequebe...

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Olivier M, Romero-Gallo BJ, Matte C, Blanchette J, Posner BI, Tremblay MJ, Faure R

Modulation of interferon-gamma-induced macrophage activation by phosphotyrosine phosphatases inhibition. Effect on murine Leishmaniasis progression

Journal Article

J Biol Chem, 273 (22), 1998.

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Contreres JO, Faure R, Baquiran G, Bergeron JJ, Posner BI

ATP-dependent desensitization of insulin binding and tyrosine kinase activity of the insulin receptor kinase. The role of endosomal acidification

Journal Article

J Biol Chem, 273 (34), 1998.

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Etongué-Mayer P, Faure R, Bouchard JP, Puymirat J

Characterization of a 54-kilodalton human protein kinase recognized by an antiserum raised against the myotonin kinase

Journal Article

Muscle Nerve, 21 (1), 1998.

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Barbeau B, Bernier R, Dumais N, Briand G, Olivier M, Faure R, Posner BI, Tremblay M

Activation of HIV-1 long terminal repeat transcription and virus replication via NF-kappaB-dependent and -independent pathways by potent phosphotyrosine phosphatase inhibitors, the peroxovanadium compounds

Journal Article

J Biol Chem, 272 (20), 1997.

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Faure R, Dussault JH

Interaction of sodium molybdate with the thyroid hormone receptor

Journal Article

Biochem Cell Biol, 68 (3), 1990.

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Faure R, Dussault JH

Effects of adenosine triphosphate and alkaline phosphatase on solubilized 3,5,3'-triiodothyronine-binding activity

Journal Article

Endocrinology, 123 (3), 1988.

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Luo M, Faure R, Ruel J, Dussault JH

A monoclonal antibody to the rat nuclear triiodothyronine receptor: production and characterization

Journal Article

Endocrinology, 123 (1), 1988.

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Faure R, Ruel J, Dussault JH

Production of an antibody against rat liver nuclear T3 receptor

Journal Article

Biochem Cell Biol, 64 (4), 1986.

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Ruel J, Faure R, Dussault JH

Regional distribution of nuclear T3 receptors in rat brain and evidence for preferential localization in neurons

Journal Article

J Endocrinol Invest, 8 (4), 1985.

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39 entries « ‹ 4 of 4 › »
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