Dr. Laforce obtained his PhD in Clinical Neuropsychology in 1998 and worked as an Assistant Professor in Cognitive Neurosciences before completing his studies in Behavioral Neurology in 2011. He performed a short Fellowship in frontotemporal dementia under Dr. Bruce Miller at the Memory and Aging Center, University of California San Francisco. He conducted brain imaging studies using FDG-PET and amyloid PET with Dr. Gil Rabinovici (University of California, Berkeley). He was co-leader of the Neurology class at Laval University for 5 years. He is a Clinician and Researcher in CHU de Québec Research Center, member of the C5R (Consortium of Canadian Centres for Clinical Cognitive Research) and RQRV (Réseau Québécois de Recherche sur le Vieillissement). Dr. Laforce obtained several major grants (CIHR, Weston Brain Institute), presented at national and international meetings, published over 100 scientific papers in prestigious journals such as Lancet Neurology, Brain, Neurology. He wrote a book on memory as well as several book chapters. Dr. Laforce is one of the PIs in the great international endeavour GENFI (Genetic Frontotemporal Dementia Initiative) and DIAN (Dominantly Inherited Alzheimer Network). He leads several research projects on the development of cognitive tools (www.dcqtest.org et www.quoco.org) and the clinical utility of molecular imaging such as FDG-PET and amyloid PET in the differential diagnosis of atypical dementias. He holds the Chaire de Recherche sur les Aphasies Primaires Progressives – Fondation Famille Lemaire (https://app-ffl.ulaval.ca/).

1401, 18e Rue
Clinique Interdisciplinaire de Mémoire
S-0071
Québec, Québec
Canada G1J 1Z4
173 entries « 2 of 18 »

Premi E, Costa T, Gazzina S, Benussi A, Cauda F, Gasparotti R, Archetti S, Alberici A, van Swieten JC, Sanchez-Valle R, Moreno F, Santana I, Laforce R, Ducharme S, Graff C, Galimberti D, Masellis M, Tartaglia C, Rowe JB, Finger E, Tagliavini F, de Mendonça A, Vandenberghe R, Gerhard A, Butler CR, Danek A, Synofzik M, Levin J, Otto M, Ghidoni R, Frisoni G, Sorbi S, Peakman G, Todd E, Bocchetta M, Rohrer JD, Borroni B,

An Automated Toolbox to Predict Single Subject Atrophy in Presymptomatic Granulin Mutation Carriers

Journal Article

J Alzheimers Dis, 86 (1), 2022.

Abstract | Links:

Choudhury S, Ghodasara S, Stiffel M, Fischer CE, Tang-Wai DF, Smith EE, Massoud F, Robin Hsiung GY, Lee L, Bruneau MA, Laforce RJ, Ismail Z, Burhan AM, Kumar S

Informant-based tools for assessment and monitoring of cognition, behavior, and function in neurocognitive disorders: Systematic review and report from a CCCDTD5 Working Group

Journal Article

Int J Geriatr Psychiatry, 37 (2), 2022.

Abstract | Links:

Poos JM, Moore KM, Nicholas J, Russell LL, Peakman G, Convery RS, Jiskoot LC, van der Ende E, van den Berg E, Papma JM, Seelaar H, Pijnenburg YAL, Moreno F, Sanchez-Valle R, Borroni B, Laforce R, Masellis M, Tartaglia C, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Vandenberghe R, de Mendonça A, Tiraboschi P, Santana I, Ducharme S, Butler C, Gerhard A, Levin J, Danek A, Otto M, Le Ber I, Pasquier F, van Swieten JC, Rohrer JD,

Cognitive composites for genetic frontotemporal dementia: GENFI-Cog

Journal Article

Alzheimers Res Ther, 14 (1), 2022.

Abstract | Links:

Ossenkoppele R, Singleton EH, Groot C, Dijkstra AA, Eikelboom WS, Seeley WW, Miller B, Laforce RJ, Scheltens P, Papma JM, Rabinovici GD, Pijnenburg YAL

Research Criteria for the Behavioral Variant of Alzheimer Disease: A Systematic Review and Meta-analysis

Journal Article

JAMA Neurol, 79 (1), 2022.

Abstract | Links:

Macoir J, Tremblay MP, Wilson MA, Laforce R, Hudon C

The Importance of Being Familiar: The Role of Semantic Knowledge in the Activation of Emotions and Factual Knowledge from Music in the Semantic Variant of Primary Progressive Aphasia

Journal Article

J Alzheimers Dis, 85 (1), 2022.

Abstract | Links:

Wilke C, Reich S, van Swieten JC, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Galimberti D, Rowe JB, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, de Mendonça A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Frisoni G, Ghidoni R, Sorbi S, Bocchetta M, Todd E, Kuhle J, Barro C, , Rohrer JD, Synofzik M

Stratifying the Presymptomatic Phase of Genetic Frontotemporal Dementia by Serum NfL and pNfH: A Longitudinal Multicentre Study

Journal Article

Ann Neurol, 91 (1), 2022.

Abstract | Links:

Levy JP, Bezgin G, Savard M, Pascoal TA, Finger E, Laforce R, Sonnen JA, Soucy JP, Gauthier S, Rosa-Neto P, Ducharme S

18F-MK-6240 tau-PET in genetic frontotemporal dementia

Journal Article

Brain, 145 (5), 2022.

Abstract | Links:

van der Ende EL, Bron EE, Poos JM, Jiskoot LC, Panman JL, Papma JM, Meeter LH, Dopper EGP, Wilke C, Synofzik M, Heller C, Swift IJ, Sogorb-Esteve A, Bouzigues A, Borroni B, Sanchez-Valle R, Moreno F, Graff C, Laforce R, Galimberti D, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, Rowe JB, de Mendonça A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Pijnenburg YAL, Sorbi S, Zetterberg H, Niessen WJ, Rohrer JD, Klein S, van Swieten JC, Venkatraghavan V, Seelaar H,

A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia

Journal Article

Brain, 145 (5), 2022.

Abstract | Links:

Peakman G, Russell LL, Convery RS, Nicholas JM, Van Swieten JC, Jiskoot LC, Moreno F, Sanchez-Valle R, Laforce R, Graff C, Masellis M, Tartaglia MC, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonça A, Butler CR, Gerhard A, Ducharme S, Le Ber I, Tagliavini F, Santana I, Pasquier F, Levin J, Danek A, Otto M, Sorbi S, Rohrer JD,

Comparison of clinical rating scales in genetic frontotemporal dementia within the GENFI cohort

Journal Article

J Neurol Neurosurg Psychiatry, 93 (2), 2022.

Abstract | Links:

Öijerstedt L, Andersson C, Jelic V, van Swieten JC, Jiskoot LC, Seelaar H, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Synofzik M, Galimberti D, Rowe JB, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Frisoni G, Ghidoni R, Sorbi S, Rohrer JD, Graff C,

Practice effects in genetic frontotemporal dementia and at-risk individuals: a GENFI study

Journal Article

J Neurol Neurosurg Psychiatry, 93 (3), 2022.

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173 entries « 2 of 18 »
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Active projects

  • Chaire de recherche sur les aphasies primaires progressives, from 2019-07-01 to 2024-06-30
  • DIAN-TU : A Phase II/III Randomized, Double-Blind, Placebo-Controlled, Cognitive Endpoint, Multicenter Study of Potential Disease Modifying Therapies in Individuals at Risk for and with Dominantly Inherited Alzheimer’s Disease, from 2020-06-01 to 2024-05-31
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, from 2019-04-01 to 2024-03-31

Recently finished projects

  • Caractérisation en TEP-18FDG du substrat neuro-fonctionnel de la dépression résistante du sujet âgé, from 2020-09-15 to 2022-04-30
  • Création et gestion d'une banque de données formée de participants intéressés à participer aux projets de recherche de la Clinique de la mémoire, from 2020-09-02 to 2021-09-01
  • Étude de l’histoire naturelle des aphasies primaires progressives, from 2020-09-15 to 2022-04-30
  • Genetic Frontotemporal dementia Initiative (GENFI), from 2014-07-01 to 2020-06-30
  • Projet de recherche sur le diagnostic différentiel de la variante frontale de la maladie d'Alzheimer et la variante comportementale de la démence frontotemporelle , from 2020-05-07 to 2021-05-06
Data provided by the Université Laval research projects registery