Dr. Laforce obtained his PhD in Clinical Neuropsychology in 1998 and worked as an Assistant Professor in Cognitive Neurosciences before completing his studies in Behavioral Neurology in 2011. He performed a short Fellowship in frontotemporal dementia under Dr. Bruce Miller at the Memory and Aging Center, University of California San Francisco. He conducted brain imaging studies using FDG-PET and amyloid PET with Dr. Gil Rabinovici (University of California, Berkeley). He was co-leader of the Neurology class at Laval University for 5 years. He is a Clinician and Researcher in CHU de Québec Research Center, member of the C5R (Consortium of Canadian Centres for Clinical Cognitive Research) and RQRV (Réseau Québécois de Recherche sur le Vieillissement). Dr. Laforce obtained several major grants (CIHR, Weston Brain Institute), presented at national and international meetings, published over 100 scientific papers in prestigious journals such as Lancet Neurology, Brain, Neurology. He wrote a book on memory as well as several book chapters. Dr. Laforce is one of the PIs in the great international endeavour GENFI (Genetic Frontotemporal Dementia Initiative) and DIAN (Dominantly Inherited Alzheimer Network). He leads several research projects on the development of cognitive tools (www.dcqtest.org et www.quoco.org) and the clinical utility of molecular imaging such as FDG-PET and amyloid PET in the differential diagnosis of atypical dementias. He holds the Chaire de Recherche sur les Aphasies Primaires Progressives – Fondation Famille Lemaire (https://app-ffl.ulaval.ca/).

1401, 18e Rue
Clinique Interdisciplinaire de Mémoire
S-0071
Québec, Québec
Canada G1J 1Z4
172 entries « 1 of 18 »

Bussiere N, Mei J, Levesque-Boissonneault C, Blais M, Carazo S, Gros-Louis F, Laforce R, De Serres G, Dupre N, Frasnelli J

Persisting chemosensory impairments in 366 healthcare workers following COVID-19: an 11-month follow-up

Journal Article

Chem Senses, 47 , 2022.

Abstract | Links:

Poos JM, MacDougall A, van den Berg E, Jiskoot LC, Papma JM, van der Ende EL, Seelaar H, Russell LL, Peakman G, Convery R, Pijnenburg YAL, Moreno F, Sanchez-Valle R, Borroni B, Laforce R, Dorà MC, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe J, Finger E, Synofzik M, Vandenberghe R, Mendonça A, Tiraboschi P, Santana I, Ducharme S, Butler C, Gerhard A, Levin J, Danek A, Otto M, Le Ber I, Pasquier F, van Swieten J, Rohrer JD,

Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort

Journal Article

Neurology, 2022.

Abstract | Links:

Wilson KM, Katona E, Glaria I, Carcolé M, Swift IJ, Sogorb-Esteve A, Heller C, Bouzigues A, Heslegrave AJ, Keshavan A, Knowles K, Patil S, Mohapatra S, Liu Y, Goyal J, Sanchez-Valle R, Laforce RJ, Synofzik M, Rowe JB, Finger E, Vandenberghe R, Butler CR, Gerhard A, Van Swieten JC, Seelaar H, Borroni B, Galimberti D, de Mendonça A, Masellis M, Tartaglia MC, Otto M, Graff C, Ducharme S, Schott JM, Malaspina A, Zetterberg H, Boyanapalli R, Rohrer JD, Isaacs AM,

Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis

Journal Article

J Neurol Neurosurg Psychiatry, 2022.

Abstract | Links:

Gazzina S, Grassi M, Premi E, Alberici A, Benussi A, Archetti S, Gasparotti R, Bocchetta M, Cash DM, Todd EG, Peakman G, Convery RS, van Swieten JC, Jiskoot LC, Seelaar H, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, de Mendonça A, Tagliavini F, Butler CR, Santana I, Gerhard A, Ber IL, Pasquier F, Ducharme S, Levin J, Danek A, Sorbi S, Otto M, Rohrer JD, Borroni B,

Structural brain splitting is a hallmark of Granulin-related frontotemporal dementia

Journal Article

Neurobiol Aging, 114 , 2022.

Abstract | Links:

Bouzigues A, Russell LL, Peakman G, Bocchetta M, Greaves CV, Convery RS, Todd E, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Tartaglia MC, Finger E, van Swieten JC, Seelaar H, Jiskoot L, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Rohrer JD,

Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations

Journal Article

J Neurol, 2022.

Abstract | Links:

Foster PH, Russell LL, Peakman G, Convery RS, Bouzigues A, Greaves CV, Bocchetta M, Cash DM, van Swieten JC, Jiskoot LC, Moreno F, Sanchez-Valle R, Laforce R, Graff C, Masellis M, Tartaglia C, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonça A, Butler CR, Gerhard A, Ducharme S, Le Ber I, Tagliavini F, Santana I, Pasquier F, Levin J, Danek A, Otto M, Sorbi S, Rohrer JD,

Examining empathy deficits across familial forms of frontotemporal dementia within the GENFI cohort

Journal Article

Cortex, 150 , 2022.

Abstract | Links:

Shafiei G, Bazinet V, Dadar M, Manera AL, Collins DL, Dagher A, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, de Mendonça A, Tagliavini F, Santana I, Butler C, Gerhard A, Danek A, Levin J, Otto M, Sorbi S, Jiskoot LC, Seelaar H, van Swieten JC, Rohrer JD, Misic B, Ducharme S, ,

Network structure and transcriptomic vulnerability shape atrophy in frontotemporal dementia

Journal Article

Brain, 2022.

Abstract | Links:

Laforce RJ, Dallaire-Théroux C, Racine AM, Dent G, Salinas-Valenzuela C, Poulin E, Cayer AM, Bédard-Tremblay D, Rouleau-Bonenfant T, St-Onge F, Schraen-Maschke S, Beauregard JM, Sergeant N, Puymirat J

Tau positron emission tomography, cerebrospinal fluid and plasma biomarkers of neurodegeneration, and neurocognitive testing: an exploratory study of participants with myotonic dystrophy type 1

Journal Article

J Neurol, 2022.

Abstract | Links:

McCarthy J, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, de Mendonça A, Tagliavini F, Santana I, Butler C, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Ghidoni R, Sorbi S, Jiskoot LC, Seelaar H, van Swieten JC, Rohrer JD, Iturria-Medina Y, Ducharme S,

Data-driven staging of genetic frontotemporal dementia using multi-modal MRI

Journal Article

Hum Brain Mapp, 43 (6), 2022.

Abstract | Links:

Premi E, Costa T, Gazzina S, Benussi A, Cauda F, Gasparotti R, Archetti S, Alberici A, van Swieten JC, Sanchez-Valle R, Moreno F, Santana I, Laforce R, Ducharme S, Graff C, Galimberti D, Masellis M, Tartaglia C, Rowe JB, Finger E, Tagliavini F, de Mendonça A, Vandenberghe R, Gerhard A, Butler CR, Danek A, Synofzik M, Levin J, Otto M, Ghidoni R, Frisoni G, Sorbi S, Peakman G, Todd E, Bocchetta M, Rohrer JD, Borroni B,

An Automated Toolbox to Predict Single Subject Atrophy in Presymptomatic Granulin Mutation Carriers

Journal Article

J Alzheimers Dis, 86 (1), 2022.

Abstract | Links:

172 entries « 1 of 18 »
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Active projects

  • Chaire de recherche sur les aphasies primaires progressives, from 2019-07-01 to 2024-06-30
  • DIAN-TU : A Phase II/III Randomized, Double-Blind, Placebo-Controlled, Cognitive Endpoint, Multicenter Study of Potential Disease Modifying Therapies in Individuals at Risk for and with Dominantly Inherited Alzheimer’s Disease, from 2020-06-01 to 2024-05-31
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, from 2019-04-01 to 2024-03-31

Recently finished projects

  • Caractérisation en TEP-18FDG du substrat neuro-fonctionnel de la dépression résistante du sujet âgé, from 2020-09-15 to 2022-04-30
  • Création et gestion d'une banque de données formée de participants intéressés à participer aux projets de recherche de la Clinique de la mémoire, from 2020-09-02 to 2021-09-01
  • Étude de l’histoire naturelle des aphasies primaires progressives, from 2020-09-15 to 2022-04-30
  • Genetic Frontotemporal dementia Initiative (GENFI), from 2014-07-01 to 2020-06-30
  • Projet de recherche sur le diagnostic différentiel de la variante frontale de la maladie d'Alzheimer et la variante comportementale de la démence frontotemporelle , from 2020-05-07 to 2021-05-06
Data provided by the Université Laval research projects registery