Dr. Laforce obtained his PhD in Clinical Neuropsychology in 1998 and worked as an Assistant Professor in Cognitive Neurosciences before completing his studies in Behavioral Neurology in 2011. He performed a short Fellowship in frontotemporal dementia under Dr. Bruce Miller at the Memory and Aging Center, University of California San Francisco. He conducted brain imaging studies using FDG-PET and amyloid PET with Dr. Gil Rabinovici (University of California, Berkeley). He was co-leader of the Neurology class at Laval University for 5 years. He is a Clinician and Researcher in CHU de Québec Research Center, member of the C5R (Consortium of Canadian Centres for Clinical Cognitive Research) and RQRV (Réseau Québécois de Recherche sur le Vieillissement). Dr. Laforce obtained several major grants (CIHR, Weston Brain Institute), presented at national and international meetings, published over 100 scientific papers in prestigious journals such as Lancet Neurology, Brain, Neurology. He wrote a book on memory as well as several book chapters. Dr. Laforce is one of the PIs in the great international endeavour GENFI (Genetic Frontotemporal Dementia Initiative) and DIAN (Dominantly Inherited Alzheimer Network). He leads several research projects on the development of cognitive tools (www.dcqtest.org et www.quoco.org) and the clinical utility of molecular imaging such as FDG-PET and amyloid PET in the differential diagnosis of atypical dementias. He holds the Chaire de Recherche sur les Aphasies Primaires Progressives – Fondation Famille Lemaire (https://app-ffl.ulaval.ca/).

1401, 18e Rue
Clinique Interdisciplinaire de Mémoire
S-0071
Québec, Québec
Canada G1J 1Z4
201 entries « 1 of 21 »

Bocchetta M, Todd EG, Bouzigues A, Cash DM, Nicholas JM, Convery RS, Russell LL, Thomas DL, Malone IB, Iglesias JE, van Swieten JC, Jiskoot LC, Seelaar H, Borroni B, Galimberti D, Sanchez-Valle R, Laforce R, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Vandenberghe R, Finger E, Tagliavini F, de Mendonça A, Santana I, Butler CR, Ducharme S, Gerhard A, Danek A, Levin J, Otto M, Sorbi S, Le Ber I, Pasquier F, Rohrer JD,

Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia: findings from the GENetic Frontotemporal dementia Initiative cohort

Journal Article

Brain Commun, 5 (2), 2023.

Abstract | Links:

Samra K, MacDougall AM, Bouzigues A, Bocchetta M, Cash DM, Greaves CV, Convery RS, Hardy C, van Swieten JC, Seelaar H, Jiskoot LC, Moreno F, Sanchez-Valle R, Laforce R, Graff C, Masellis M, Tartaglia MC, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonça A, Butler CR, Gerhard A, Ducharme S, Le Ber I, Santana I, Pasquier F, Levin J, Otto M, Sorbi S, Warren JD, Rohrer JD, Russell LL,

Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort: comparison with sporadic primary progressive aphasia

Journal Article

Brain Commun, 5 (2), 2023.

Abstract | Links:

Premi E, Pengo M, Mattioli I, Cantoni V, Dukart J, Gasparotti R, Buratti E, Padovani A, Bocchetta M, Todd EG, Bouzigues A, Cash DM, Convery RS, Russell LL, Foster P, Thomas DL, van Swieten JC, Jiskoot LC, Seelaar H, Galimberti D, Sanchez-Valle R, Laforce R, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Tsvetanov KA, Vandenberghe R, Finger E, Tiraboschi P, de Mendonça A, Santana I, Butler CR, Ducharme S, Gerhard A, Levin J, Otto M, Sorbi S, Le Ber I, Pasquier F, Rohrer JD, Borroni B,

Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study

Journal Article

Neurobiol Dis, 179 , 2023.

Abstract | Links:

Bussy A, Levy JP, Best T, Patel R, Cupo L, Van Langenhove T, Nielsen JE, Pijnenburg Y, Waldö ML, Remes AM, Schroeter ML, Santana I, Pasquier F, Otto M, Danek A, Levin J, Le Ber I, Vandenberghe R, Synofzik M, Moreno F, de Mendonça A, Sanchez-Valle R, Laforce R, Langheinrich T, Gerhard A, Graff C, Butler CR, Sorbi S, Jiskoot L, Seelaar H, van Swieten JC, Finger E, Tartaglia MC, Masellis M, Tiraboschi P, Galimberti D, Borroni B, Rowe JB, Bocchetta M, Rohrer JD, Devenyi GA, Chakravarty MM, Ducharme S,

Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia

Journal Article

Hum Brain Mapp, 44 (7), 2023.

Abstract | Links:

Jiskoot LC, Russell LL, Peakman G, Convery RS, Greaves CV, Bocchetta M, Poos JM, Seelaar H, Giannini LAA, van Swieten JC, van Minkelen R, Pijnenburg YAL, Rowe JB, Borroni B, Galimberti D, Masellis M, Tartaglia C, Finger E, Butler CR, Graff C, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, le Ber I, Levin J, Otto M, Pasquier F, Santana I, Cash DM, Thomas D, Rohrer JD,

The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI study

Journal Article

J Neurol Sci, 446 , 2023.

Abstract | Links:

Dawes P, Reeves D, Yeung WK, Holland F, Charalambous AP, Côté M, David R, Helmer C, Laforce R, Martins RN, Politis A, Pye A, Russell G, Sheikh S, Sirois MJ, Sohrabi HR, Thodi C, Gallant K, Nasreddine Z, Leroi I

Development and validation of the Montreal cognitive assessment for people with hearing impairment (MoCA-H)

Journal Article

J Am Geriatr Soc, 71 (5), 2023.

Abstract | Links:

Ottoy J, Ozzoude M, Zukotynski K, Kang MS, Adamo S, Scott C, Ramirez J, Swardfager W, Lam B, Bhan A, Mojiri P, Kiss A, Strother S, Bocti C, Borrie M, Chertkow H, Frayne R, Hsiung R, Laforce RJ, Noseworthy MD, Prato FS, Sahlas DJ, Smith EE, Kuo PH, Chad JA, Pasternak O, Sossi V, Thiel A, Soucy JP, Tardif JC, Black SE, Goubran M,

Amyloid-PET of the white matter: Relationship to free water, fiber integrity, and cognition in patients with dementia and small vessel disease

Journal Article

J Cereb Blood Flow Metab, 43 (6), 2023.

Abstract | Links:

Samra K, Macdougall A, Peakman G, Bouzigues A, Bocchetta M, Cash DM, Greaves CV, Convery RS, van Swieten JC, Jiskoot LC, Seelaar H, Moreno F, Sánchez-Valle R, Laforce R, Graff C, Masellis M, Tartaglia MC, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonca A, Butler CR, Gerhard A, Ducharme S, Le Ber I, Tiraboschi P, Santana I, Pasquier F, Levin J, Otto M, Sorbi S, Rohrer JD, Russell LL, ,

Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating Scales

Journal Article

J Neurol Neurosurg Psychiatry, 94 (5), 2023.

Abstract | Links:

Samra K, MacDougall AM, Bouzigues A, Bocchetta M, Cash DM, Greaves CV, Convery RS, van Swieten JC, Seelaar H, Jiskoot L, Moreno F, Sanchez-Valle R, Laforce R, Graff C, Masellis M, Tartaglia MC, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonça A, Butler CR, Gerhard A, Ducharme S, Le Ber I, Tiraboschi P, Santana I, Pasquier F, Levin J, Otto M, Sorbi S, Rohrer JD, Russell LL,

Language impairment in the genetic forms of behavioural variant frontotemporal dementia

Journal Article

J Neurol, 270 (4), 2023.

Abstract | Links:

Pérez-Millan A, Borrego-Écija S, van Swieten JC, Jiskoot L, Moreno F, Laforce R, Graff C, Masellis M, Tartaglia MC, Rowe JB, Borroni B, Finger E, Synofzik M, Galimberti D, Vandenberghe R, de Mendonça A, Butler CR, Gerhard A, Ducharme S, Le Ber I, Santana I, Pasquier F, Levin J, Otto M, Sorbi S, Tiraboschi P, Seelaar H, Langheinrich T, Rohrer JD, Sala-Llonch R, Sánchez-Valle R,

Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study

Journal Article

J Neurol, 270 (3), 2023.

Abstract | Links:

201 entries « 1 of 21 »
Signaler des ajouts ou des modifications

Active projects

  • Chaire de recherche sur les aphasies primaires progressives, from 2019-07-01 to 2024-06-30
  • DIAN-TU : A Phase II/III Randomized, Double-Blind, Placebo-Controlled, Cognitive Endpoint, Multicenter Study of Potential Disease Modifying Therapies in Individuals at Risk for and with Dominantly Inherited Alzheimer’s Disease, from 2020-06-01 to 2024-05-31
  • Genetic Frontotemporal Dementia Initiative (GENFI) in Canada: Combined Investigation of Clinical, MRI, Genomic, and Epigenomic Biomarkers, from 2021-04-01 to 2026-03-31
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, from 2019-04-01 to 2024-03-31

Recently finished projects

  • Caractérisation en TEP-18FDG du substrat neuro-fonctionnel de la dépression résistante du sujet âgé, from 2020-09-15 to 2022-04-30
  • Création et gestion d'une banque de données formée de participants intéressés à participer aux projets de recherche de la Clinique de la mémoire, from 2020-09-02 to 2021-09-01
  • Étude de l’histoire naturelle des aphasies primaires progressives, from 2020-09-15 to 2022-04-30
Data provided by the Université Laval research projects registery