Philippe Després is an Associate Professor in the Department of Physics, Engineering Physics and Optics and member of the Cancer Research Center of Université Laval, as well as a Medical Physicist at CHU de Québec and a regular researcher at its affiliated Research Center. He was trained at Université Laval (MSc 2000, Physics), Université de Montréal (PhD 2005, Physics) and University of California, San Francisco (postdoc 2005-2007, Biomedical Engineering, Molecular Imaging). He is involved in several projects encompassing hardware and software aspects of medical imaging modalities, notably low-dose X-ray imaging, advanced imaging techniques, and solid-state detectors for molecular imaging. He pioneered high-performance computing (HPC) approaches with commodity graphics hardware (GPUs) that led to innovative applications in image processing/reconstruction and radiation dose calculations, including a fast GPU-based Monte Carlo engine to simulate energy transport in matter (GPUMCD). As a HPC expert, he is also involved in data-driven research approaches, data infrastructures and FAIR-compliant research data management. In this regard, he is the Chief Data Officer at CHU de Québec – Université Laval Research Center, the Data Architect of the PULSAR health research platform, the Assistant Director of the Big Data Research Center at Université Laval, and the co-lead of the Sustainable Health axis of the Observatoire international sur les impacts sociétaux de l’IA et du numérique.

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Carignan D, Morales B, Després P, Foster W, Martin AG, Vigneault E

Differential outcomes of re-stratified high-risk prostate cancer patients treated with external beam radiation therapy plus high-dose-rate brachytherapy boost

Journal Article

J Contemp Brachytherapy, 16 (2), 2024.

Abstract | Links:

Walker MJ, Blackmore KM, Chang A, Lambert-Côté L, Turgeon A, Antoniou AC, Bell KA, Broeders MJM, Brooks JD, Carver T, Chiquette J, Després P, Easton DF, Eisen A, Eloy L, Evans DG, Fienberg S, Joly Y, Kim RH, Kim SJ, Knoppers BM, Lofters AK, Nabi H, Paquette JS, Pashayan N, Sheppard AJ, Stockley TL, Dorval M, Simard J, Chiarelli AM

Implementing Multifactorial Risk Assessment with Polygenic Risk Scores for Personalized Breast Cancer Screening in the Population Setting: Challenges and Opportunities

Journal Article

Cancers (Basel), 16 (11), 2024.

Abstract | Links:

Dia AK, Ebrahimpour L, Yolchuyeva S, Tonneau M, Lamaze FC, Orain M, Coulombe F, Malo J, Belkaid W, Routy B, Joubert P, Després P, Manem VSK

The Cross-Scale Association between Pathomics and Radiomics Features in Immunotherapy-Treated NSCLC Patients: A Preliminary Study

Journal Article

Cancers (Basel), 16 (2), 2024.

Abstract | Links:

Ouellet S, Lemaréchal Y, Berumen-Murillo F, Lavallée MC, Vigneault É, Martin AG, Foster W, Thomson RM, Després P, Beaulieu L

A Monte Carlo dose recalculation pipeline for durable datasets: an I-125 LDR prostate brachytherapy use case

Journal Article

Phys Med Biol, 68 (23), 2023.

Abstract | Links:

Sasseville M, Ouellet S, Rhéaume C, Couture V, Després P, Paquette JS, Gentelet K, Darmon D, Bergeron F, Gagnon MP

Risk of Bias Mitigation for Vulnerable and Diverse Groups in Community-Based Primary Health Care Artificial Intelligence Models: Protocol for a Rapid Review

Journal Article

JMIR Res Protoc, 12 , 2023.

Abstract | Links:

Beaudry MM, Carignan D, Foster W, Lavallee MC, Aubin S, Lacroix F, Poulin E, Lachance B, Després P, Beaulieu L, Vigneault E, Martin AG

Comparison of four-year toxicities and local control of ultra-hypofractionated vs moderate-hypofractionated image guided prostate radiation with HDR brachytherapy boost: A phase I-II single institution trial

Journal Article

Clin Transl Radiat Oncol, 40 , 2023.

Abstract | Links:

Di Schiavi Trotta L, Matenine D, Lemaréchal Y, Martini M, Stierstorfer K, des Roches M, Letellier P, Francus P, Després P

Tomographic reconstruction strategies for nondestructive testing with a commercial CT scanner

Journal Article

Frontiers in Earth Science, 11 , 2023.

Abstract | Links:

Desy A, Bouvet GF, Lafrenière N, Zamanian A, Després P, Beauregard JM

Impact of the dead-time correction method on quantitative 177Lu-SPECT (QSPECT) and dosimetry during radiopharmaceutical therapy

Journal Article

EJNMMI Phys, 9 (1), 2022.

Abstract | Links:

Di Schiavi Trotta L, Matenine D, Martini M, Stierstorfer K, Lemaréchal Y, Francus P, Després P

Beam-hardening corrections through a polychromatic projection model integrated to an iterative reconstruction algorithm

Journal Article

NDT E Int, 126 , 2022.

| Links:

Brunelle C, Francus P, Camenen B, Amos CL, Des Roches M, Perret E, Kassem H, Daigle LF, Després P

X-Ray Computed Tomography to Measure Bed Density in Sand Transpor

Journal Article

Journal of hydraulic engineering, 148 (12), 2022.

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Active projects

  • ALPHAgenomics: Integrationg genomic and phenomic for the swine industry, from 2021-10-01 to 2024-09-30
  • Developing a breast cancer data access platform, from 2024-09-01 to 2026-08-31
  • Genovalia - Phase 1, from 2021-03-31 to 2026-03-31
  • Genovalia - Phase 2, from 2024-04-01 to 2027-03-31
  • High-Performance Computing in Medical Physics, from 2018-04-01 to 2026-03-31
  • Meilleures Pratiques en Oncologie Pédiatrique : recherche appliquée auprès des Familles (MP OncoPed-Familles), from 2022-01-15 to 2028-03-31
  • NSERC CREATE in Responsible Health and Healthcare Data Science, from 2019-09-01 to 2026-08-31
  • Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique, from 2018-04-01 to 2025-03-31
  • Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique (OBVIA) - Renouvellement, from 2023-04-01 to 2028-03-31
  • Personalized risk-stratified breast cancer follow-up care: a feasibility and acceptability study, from 2023-06-26 to 2026-06-30
  • Réseau RSN - Réseau de santé numérique, from 2024-04-01 to 2028-03-31
  • Télé-NEUROS (Nouvel Environnement Universitaire de Recherche Orchestrée en Santé mentale et cognitive: une télé initiative), from 2020-10-20 to 2026-03-31
  • Towards Personalized Dosimetry-Based Radioligand Therapy of Prostate Cancer as a New Standard of Practice, from 2022-04-01 to 2027-03-31

Recently finished projects

  • Aide à la décision pour le dépistage par tomodensitométrie basse dose en cancer du poumon: ancrer des outils basés sur l'IA dans des environnements numériques multi-juridisctionnels et favoriser leur adoption clinique, from 2021-04-01 to 2024-03-31
  • Banque de données en santé durable (BDSD) de PULSAR, from 2021-08-18 to 2023-12-31
  • Des tests qui gênent : comment mieux protéger le droit à la vie privée à l'ère des tests génétiques en ligne, from 2023-07-01 to 2024-06-30
  • Design and implementation of new data governance model in the digital health era; PULSAR as a responsible innovation test bench, from 2020-09-01 to 2023-08-31
  • Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle, from 2020-04-01 to 2023-03-31
  • Linking clinical, research and imaging data in lung cancer: towards FAIR and AI-ready datasets, from 2022-03-15 to 2023-03-14
  • Major Resource Support for the Particle Physics Group at Université de Montréal, from 2018-04-01 to 2024-03-31
  • Optimiser les soins des patients atteints du cancer de la prostate résistant à la castration en utilisant une stratégie de triple traceur en imagerie moléculaire et en radiothérapieléculaire et en radiothérapie ciblée, from 2018-04-01 to 2023-06-30
  • Plateforme collaborative d’outils d’aide à la décision, from 2021-04-01 to 2022-12-20
  • Prédire l'évolution de l'hépatite C par la fédération de données et l'intelligence artificielle : enjeux éthiques, juridiques, sociaux et de vie privée, from 2019-04-01 to 2024-03-31
  • Protéger et Engager les populations vulnérables dans le développement des modèles prédictifs en soins de santé primaires pour IA inclusive, diversifiée et équiptable (PREMIA), from 2021-07-01 to 2024-06-30
  • Une infrastructure IA multi-usagers clé en main pour gérer le cycle de vie complet des données en santé, from 2021-04-01 to 2024-06-30
  • Vers une infrastructure numérique robuste et des outils innovants en recherche axée sur les données en santé, from 2020-07-01 to 2023-06-30
  • WikiSanté : Vers l'élaboration d'une plateforme collaborative de partage de connaissances en situation de COVID-19 au Centre intégré de santé et de services sociaux de Chaudière-Appalaches (CISSS-CA), from 2020-09-01 to 2023-08-31
Data provided by the Université Laval research projects registery