Dr. Le Sage has been practicing as an emergency physician for more than 30 years at the Hopital de l’Enfant-Jésus du CHU de Québec-Université Laval. She is also a clinical researcher at the Research Center of this institution and at VITAM Research Center.

In addition, she is a full clinical professor at Université Laval Faculty of Medicine and has been a member of the Program Committee of Emergency Medicine for over 15 years. Holding a PhD in epidemiology, she never stopped to be involved in the development of a research program in emergency medicine at Université Laval. She has also been a member of the Clinician Scientist Program of the Royal College of Physicians and Surgeons of Canada at Laval University.

To date, her research work emphasized on emergency and trauma medicine, and her research program – PoCS Research Program – has focused on concussions (mild Traumatic Brain Injuries) and the prognosis factors that could predict long-term evolution after such trauma, including the possibility of using biomarkers.

With her dual expertise (clinical and research), she is regularly involved as a medical expert on various committees at MSSS and INESSS. Indeed, the importance of disseminating best evidence knowledge has always been at the heart of her concerns.

At the twilight of her career, Dr. Le Sage recently changed her focus and will now devote her full clinical time working in medical assistance in dying (MAID).

1401, 18e Rue
H-602
Québec, Québec
Canada G1J 1Z4
+1 418-649-0252, extension 64169
+1 418-649-5406
Natalie.Lesage@crchudeque... natalie.lesage@fmed.ulava...

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Silverberg ND, Iverson GL, , Cogan A, Dams-O'Connor K, Delmonico R, Graf MJP, Iaccarino MA, Kajankova M, Kamins J, McCulloch KL, McKinney G, Nagele D, Panenka WJ, Rabinowitz AR, Reed N, Wethe JV, Whitehair V, , Anderson V, Arciniegas DB, Bayley MT, Bazarian JJ, Bell KR, Broglio SP, Cifu D, Davis GA, Dvorak J, Echemendia RJ, Gioia GA, Giza CC, Hinds SR, Katz DI, Kurowski BG, Leddy JJ, Sage NL, Lumba-Brown A, Maas AIR, Manley GT, McCrea M, Menon DK, Ponsford J, Putukian M, Suskauer SJ, van der Naalt J, Walker WC, Yeates KO, Zafonte R, Zasler ND, Zemek R

The American Congress of Rehabilitation Medicine Diagnostic Criteria for Mild Traumatic Brain Injury

Journal Article

Arch Phys Med Rehabil, 2023.

Abstract | Links:

Hudek N, Brehaut JC, Rowe BH, Nguyen PA, Ghaedi B, Ishimwe AC, Fabian C, Yan JW, Sivilotti MLA, Ohle R, Le Sage N, Mercier E, Archambault PM, Plourde M, Davis P, McRae AD, Hegdekar M, Thiruganasambandamoorthy V

Development of practice recommendations based on the Canadian Syncope Risk Score and identification of barriers and facilitators for implementation

Journal Article

CJEM, 25 (5), 2023.

Abstract | Links:

Mercier É, Nadeau A, Le Sage N, Moore L, Malo C, Blanchard PG, Fleet R, Émond M

A Canadian consensus-based list of urgent and specialized in-hospital trauma care interventions to assess the accuracy of prehospital trauma triage protocols: a modified Delphi study

Journal Article

Can J Surg, 66 (2), 2023.

Abstract | Links:

Caron L, Ouellet MC, Hudon C, Predovan D, Sirois MJ, de Guise É, Lamontagne MÈ, Émond M, Le Sage N, Beaulieu-Bonneau S

Cognitive functioning following traumatic brain injury in older adults: associations with social participation and health-related quality of life

Journal Article

Brain Inj, 36 (9), 2022.

Abstract | Links:

Le Sage N, Sage NL, Chauny JM, Berthelot S, Archambault P, Neveu X, Moore L, Boucher V, Frenette J, De Guise É, Ouellet MC, Lee J, McRae AD, Lang E, Émond M, Mercier É, Tardif PA, Swaine B, Cameron P, Perry JJ

Post-Concussion Symptoms Rule: Derivation and Validation of a Clinical Decision Rule for Early Prediction of Persistent Symptoms after a Mild Traumatic Brain Injury

Journal Article

J Neurotrauma, 39 (19-20), 2022.

Abstract | Links:

Émond M, Lachance-Perreault D, Boucher V, Carmichael PH, Turgeon J, Brousseau AA, Akoum A, Tourigny JN, Le Sage N

The impact of post-intubation hypotension on length of stay and mortality in adult and geriatric patients: a cohort study

Journal Article

CJEM, 24 (5), 2022.

Abstract | Links:

Lamontagne G, Belleville G, Beaulieu-Bonneau S, Souesme G, Savard J, Sirois MJ, Giguère M, Tessier D, Le Sage N, Ouellet MC

Anxiety symptoms and disorders in the first year after sustaining mild traumatic brain injury

Journal Article

Rehabil Psychol, 67 (1), 2022.

Abstract | Links:

Thiruganasambandamoorthy V, Yan JW, Rowe BH, Mercier É, Le Sage N, Hegdekar M, Finlayson A, Huang P, Mohammad H, Mukarram M, Nguyen PAI, Syed S, McRae AD, Nemnom MJ, Taljaard M, Silviotti M

Personalised risk prediction following emergency department assessment for syncope

Journal Article

Emerg Med J, 39 (7), 2022.

Abstract | Links:

Ouellet V, Boucher V, Beauchamp F, Neveu X, Archambault P, Berthelot S, Chauny JM, De Guise E, Émond M, Frenette J, Lang E, Lee J, Mercier , Moore L, Ouellet MC, Perry J, Le Sage N

Influence of concomitant injuries on post-concussion symptoms after a mild traumatic brain injury - a prospective multicentre cohort study

Journal Article

Brain Inj, 35 (9), 2021.

Abstract | Links:

Silverberg ND, Iverson GL,

Expert Panel Survey to Update the American Congress of Rehabilitation Medicine Definition of Mild Traumatic Brain Injury

Journal Article

Arch Phys Med Rehabil, 102 (1), 2021.

Abstract | Links:

75 entries « ‹ 1 of 8 › »
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Research field

  • Trauma – Emergency Medicine – mTBI (concussion)

Research theme(s)

  • Clinical research and treatment protocols
  • Organizational assessment of trauma and emergency systems

Research interests

  • Trauma and emergency medicine
  • Quality of care evaluation protocols
  • Development and validation of clinical prediction rules
  • Injury surveillance and prevention

Active projects

  • Système canadien hospitalier d'information sur la recherche en prévention des traumatismes (SCHIRPT), from 2014-04-01 to 2025-03-31

Recently finished projects

  • La protéine S100B est-elle un outil de dépistage valide pour réduire le nombre de tomodensitométries inutiles suite à un traumatisme cranio-cérébral léger?, from 2017-04-01 to 2022-01-31
Data provided by the Université Laval research projects registery