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23 entries « 1 of 3 »

Belmas T, Liesa M, Shum M

Quantifying mitochondrial redox and bilirubin content in intact primary hepatocytes of obese mice using fluorescent reporters

Journal Article

STAR Protoc, 4 (3), 2023.

Abstract | Links:

Zeng J, Acin-Perez R, Assali EA, Martin A, Brownstein AJ, Petcherski A, Fernández-Del-Rio L, Xiao R, Lo CH, Shum M, Liesa M, Han X, Shirihai OS, Grinstaff MW

Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease

Journal Article

Nat Commun, 14 (1), 2023.

Abstract | Links:

Gonthier K, Weidmann C, Berthiaume L, Jobin C, Lacouture A, Lafront C, Harvey M, Neveu B, Loehr J, Bergeron A, Fradet Y, Lacombe L, Riopel J, Latulippe É, Atallah C, Shum M, Lambert JP, Pouliot F, Pelletier M, Audet-Walsh É

Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer

Journal Article

Mol Oncol, 2023.

Abstract | Links:

Shum M, Segawa M, Gharakhanian R, Viñuela A, Wortham M, Baghdasarian S, Wolf DM, Sereda SB, Nocito L, Stiles L, Zhou Z, Gutierrez V, Sander M, Shirihai OS, Liesa M

Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance

Journal Article

Mol Metab, 55 , 2022.

Abstract | Links:

Shum M, Zhou Z, Liesa M

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice

Journal Article

J Vis Exp, (177), 2021.

Abstract | Links:

Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, Mouisel E, Pan C, Moore TM, Péterfy M, Romanoski CE, Reue K, Björkegren JLM, Laakso M, Liesa M, Lusis AJ

Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2

Journal Article

Nat Metab, 3 (11), 2021.

Abstract | Links:

Ngo J, Benador IY, Brownstein AJ, Vergnes L, Veliova M, Shum M, Acín-Pérez R, Reue K, Shirihai OS, Liesa M

Isolation and functional analysis of peridroplet mitochondria from murine brown adipose tissue

Journal Article

STAR Protoc, 2 (1), 2021.

Abstract | Links:

Shum M, Ngo J, Shirihai OS, Liesa M

Mitochondrial oxidative function in NAFLD: Friend or foe?

Journal Article

Mol Metab, 50 , 2021.

Abstract | Links:

Shum M, Shintre CA, Althoff T, Gutierrez V, Segawa M, Saxberg AD, Martinez M, Adamson R, Young MR, Faust B, Gharakhanian R, Su S, Chella Krishnan K, Mahdaviani K, Veliova M, Wolf DM, Ngo J, Nocito L, Stiles L, Abramson J, Lusis AJ, Hevener AL, Zoghbi ME, Carpenter EP, Liesa M

ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity

Journal Article

Sci Transl Med, 13 (594), 2021.

Abstract | Links:

van Veen JE, Kammel LG, Bunda PC, Shum M, Reid MS, Massa MG, Arneson D, Park JW, Zhang Z, Joseph AM, Hrncir H, Liesa M, Arnold AP, Yang X, Correa SM

Hypothalamic estrogen receptor alpha establishes a sexually dimorphic regulatory node of energy expenditure

Journal Article

Nat Metab, 2 (4), 2020.

Abstract | Links:

23 entries « 1 of 3 »
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Active projects

  • Fonds de démarrage, Michael Shum, from 2021-01-11 to 2024-01-10
  • Understanding mitochondria and lipids droplet interactions in cell biology, from 2021-04-01 to 2026-03-31

Recently finished projects

  • Understanding mitochondria and lipids droplet interactions in cell biology, from 2021-04-01 to 2022-03-31
Data provided by the Université Laval research projects registery