Dr. Martin Simard, Ph.D., holds a Research Chair of the Fonds de Recherche-Santé du Québec and is professor in the Department of molecular biology, medical biochemistry, and pathology of the Laval University School of Medicine.
His research group aims to better understand how small non-coding RNAs can so efficiently control gene expression, in animals. Those molecules able to precisely control the protein production (the genes) in cells, have promptly being proposed to be implicated in different pathologies such as different types of cancers and recent scientific studies have proven their roles. The contribution of theses tiny molecules to our understanding of the cell, as well as their great potential in the detection and treatment of different diseases, makes this field of research among the most active in medical biology. His work focuses on the identification of cellular molecules that participate in the biological role of small non-coding RNAs, on understanding their roles and defining their implication in the development of different pathologies, such as cancers. At term, our studies will contribute to gather new insights about how theses tiny molecules contribute to cell function, and to develop new therapeutic strategies using the small non-coding RNAs.
9, rue McMahon
0744-5
Québec, Québec
Canada G1R 2J6
- Bouchard Dostie, ÉmilieEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15543emilie.bouchard-dostie@crchudequebec.ulaval.ca
9 rue McMahon
0709
Québec, QC
Canada G1R 3S3 - Champagne, JeanneInternjeanne.champagne.1@ulaval.ca
- Frédérick, Pierre-MarcDoctoral studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16949pierre-marc.frederick.1@ulaval.capierre-marc.frederick@crchudequebec.ulaval.ca
9, rue McMahon
0744
Québec, Québec
Canada G1R 3S3 - Harvey, Louis-MathieuDoctoral studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16949louis-mathieu.harvey@crchudequebec.ulaval.ca
9 Rue Mcmahon
0744
Ville de Québec, QC
Canada G1R 3S3 - Houle, FrançoisEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16949+1 418-691-5439Francois.Houle@crchudequebec.ulaval.ca
9, rue McMahon
0744
Québec, Québec
Canada G1R 2J6 - Pal, AnishaDoctoral studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16972anisha.pal.1@ulaval.caanisha.pal@crchudequebec.ulaval.ca
9 Rue Mcmahon
Ville de Québec, QC
Canada G1R 3S3 - Pulichino, Anne-MarieEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15061+1 418-691-5439Anne-Marie.Pulichino@crchudequebec.ulaval.ca
9, rue McMahon
2765
Québec, Québec
Canada G1R 2J6 - Quévillon-Huberdeau, MiguelDoctoral studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16949+1 418-691-5439miguel.quevillon-huberdeau.1@ulaval.camiguel.quevillon-huberdeau@crchudequebec.ulaval.ca
9, rue McMahon
0744
Québec, Québec
Canada G1R 2J6 - Quévillon-Huberdeau, MiguelEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16949+1 418-691-5439miguel.quevillon-huberdeau.1@ulaval.camiguel.quevillon-huberdeau@crchudequebec.ulaval.ca
9, rue McMahon
0744
Québec, Québec
Canada G1R 2J6 - Shah, VivekDoctoral studentL'Hôtel-Dieu de Québecvivek.shah.1@ulaval.cavivek.shah@crchudequebec.ulaval.ca
9, Rue Mcmahon
0744
Québec, QC
Canada G1R 3S3 - Vasudevan, VaishnavDoctoral studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16949vaishnav.vasudevan@crchudequebec.ulaval.ca
9 Rue McMahon
0744
Québec, QC
Canada G1R 3S3
Human let-7a miRNA blocks protein production on actively translating polyribosomes
Journal ArticleNat Struct Mol Biol, 13 (12), 2006.
Tumour-related microRNAs functions in Caenorhabditis elegans
Journal ArticleOncogene, 25 (46), 2006.
Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi
Journal ArticleCell, 127 (4), 2006.
A member of the polymerase beta nucleotidyltransferase superfamily is required for RNA interference in C. elegans
Journal ArticleCurr Biol, 15 (4), 2005.
Active projects
- Deciphering cellular modulators of the microRNA pathway, from 2023-03-01 to 2024-02-29
- Genetic and molecular analysis of the siRNA-mediated gene regulation, from 2019-04-01 to 2024-03-31
- Understanding the regulation and implication of Argonaute in microRNA-mediated gene silencing., from 2020-10-01 to 2025-09-30
Recently finished projects
- Acquisition d'un appareil PCR pour analyses d'échantillons biologiques , from 2021-07-16 to 2022-07-15
- Canadian Developmental Biology Conference 2023, from 2021-04-01 to 2023-03-31