Dr. Gauthier is Assistant Professor of Palliative Care in the Department of Family Medicine and Emergency Medicine of the Faculty of Medicine at Laval University. She is also a regular researcher in the oncology axis of the CHU of Quebec-Laval University Research Centre, as well as in the Michel-Sarrazin Research Team in Psychosocial Oncology and Palliative Care (ERMOS). She is also co-director of the Axis 1 of the Quebec Research Network in Palliative and End-of-Life Care (RQSPAL) and a regular member of the Quebec Pain Research Network. She completed her PhD at the School of Kinesiology and Health Sciences at York University in Toronto in 2013 and her postdoctoral at the Princess Margaret Cancer Center in 2016. Her research goals are at the intersection of pain and aging. Her main objective is to improve the assessment and management of pain during adulthood, particularly in the elderly population. Dr. Gauthier aims to deepen our understanding of pain, its management, as well as to identify ways to improve it in order to reduce patients’ suffering.

The overall impact of chemotherapy-induced peripheral neuropathies

Women using taxane-based chemotherapy to treat breast cancer may experience persistent side effects from these treatments, such as chemically-induced peripheral neuropathy (CIPN). These symptoms include weakness, pain, numbness, altered sensitivity, tingling, or burning sensations in the hands and feet. These symptoms can cause temperature-related injuries, balance problems, falls, and a deterioration in the quality of life. Unfortunately, our knowledge of CIPN and the best way to measure it are limited. As part of her research projects, Dr. Gauthier is interested in examining the psychometric properties of measures used to evaluate chemically-induced peripheral neuropathy, in order to improve our understanding of the development, trajectory, biopsychosocial risk factors, and impacts of CIPN by age. Additionally, by comparing the validity of existing measures used in evaluating acute and chronic CIPNs, it will be possible to better determine which of the measures has the best validity and should serve as basis for the development of a new measure, if necessary.

Hôpital de l'Enfant-Jésus
1401, 18e rue
G2.615
Québec, QC
Canada G1J 1Z4
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Bérubé-Mercier P, Tapp D, Cimon MÈ, Li T, Park SB, Bouhêlier É, McGarragle K, Robichaud LA, Gewandter JS, Bouchard M, Gauthier LR

Evaluation of the psychometric properties of patient-reported and clinician-reported outcome measures of chemotherapy-induced peripheral neuropathy: a COSMIN systematic review protocol

Journal Article

BMJ Open, 12 (4), 2022.

Abstract | Links:

Bordeleau M, Léonard G, Gauthier L, Ferland CE, Backonja M, Vollert J, Marchand S, Jackson P, Cantin L, Prud'Homme M

Classification of Qualitative Fieldnotes Collected During Quantitative Sensory Testing: A Step Towards the Development of a New Mixed Methods Approach in Pain Research

Journal Article

J Pain Res, 14 , 2021.

Abstract | Links:

Graham CA, Chaves G, Harrison R, Gauthier LR, Nissim R, Zimmermann C, Chan V, Rodin G, Stevens B, Gagliese L

Health Care Professionals' Reports of Cancer Pain Cues Among Older People With Delirium: A Qualitative-Quantitative Content Analysis

Journal Article

J Pain Symptom Manage, 60 (1), 2020.

Abstract | Links:

Merlin JS, Young SR, Arnold R, Bulls HW, Childers J, Gauthier L, Giannitrapani KF, Kavalieratos D, Schenker Y, Wilson JD, Liebschutz JM

Managing Opioids, Including Misuse and Addiction, in Patients With Serious Illness in Ambulatory Palliative Care: A Qualitative Study

Journal Article

Am J Hosp Palliat Care, 37 (7), 2020.

Abstract | Links:

Janah A, Gauthier LR, Morin L, Bousquet PJ, Le Bihan C, Tuppin P, Peretti-Watel P, Bendiane MK

Access to palliative care for cancer patients between diagnosis and death: a national cohort study

Journal Article

Clin Epidemiol, 11 , 2019.

Abstract | Links:

Gagnon P, Dumont S, Cohen R, Gauthier LR, Savard J, Tardif F, Maranda-Pelletier S

Création d’une force majeure de recherche en soins palliatifs au Québec: le RQSPAL

Journal Article

Cahiers francophones de soins palliatifs, 18 (1), 2018.

Mah K, Tran KT, Gauthier LR, Rodin G, Zimmermann C, Warr D, Librach SL, Moore M, Shepherd FA, Gagliese L

Do Correlates of Pain-Related Stoicism and Cautiousness Differ in Younger and Older People With Advanced Cancer?

Journal Article

J Pain, 19 (3), 2018.

Abstract | Links:

St-Pierre D, Bouchard K, Gauthier L, Chiquette J, Dorval M,

Perspectives of Women Considering Bilateral Prophylactic Mastectomy and their Peers towards a Telephone-Based Peer Support Intervention

Journal Article

J Genet Couns, 27 (1), 2018.

Abstract | Links:

Gauthier LR, Dworkin RH, Warr D, Pillai Riddell R, Macpherson AK, Rodin G, Zimmermann C, Lawrence Librach S, Moore M, Shepherd FA, Gagliese L

Age-Related Patterns in Cancer Pain and Its Psychosocial Impact: Investigating the Role of Variability in Physical and Mental Health Quality of Life

Journal Article

Pain Med, 19 (4), 2018.

Abstract | Links:

Gagliese L, Gauthier LR, Narain N, Freedman T

Pain, aging and dementia: Towards a biopsychosocial model

Journal Article

Prog Neuropsychopharmacol Biol Psychiatry, 87 (Pt B), 2018.

Abstract | Links:

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Active projects

  • Age-related patterns in the experience of chemotherapy-induced peripheral neuropathy, from 2019-10-01 to 2024-09-30
  • Chaire de soins palliatifs de l'Université Laval, from 2012-10-01 to 2023-09-02
  • La neuropathie périphérique chimio-induite chez les femmes de différents âges recevant une chimiothérapie à base de taxane pour un cancer du sein, from 2018-07-01 to 2022-10-31
  • Soutien financier Fondation JL Lévesque, from 2019-04-01 to 2023-03-31
  • Subvention d’établissement de jeune chercheur - Lynn Gauthier, from 2018-07-01 to 2022-06-30
  • Uncovering Quality of life and Pain Experience Among Hispanic Breast Cancer Survivors, from 2022-03-16 to 2023-03-31

Recently finished projects

  • Development and initial validation of measures of cancer pain under- and overtreatment, from 2020-04-01 to 2021-03-31
  • Fonds de démarrage (Chaire en soins palliatifs), from 2016-04-01 to 2021-03-31
  • Programme de soutien aux nouveaux chercheurs, from 2018-07-01 to 2020-06-30
Data provided by the Université Laval research projects registery