Dr. Louis Bessette graduated from medical school and completed his residency in Internal Medicine and Rheumatology at Laval University. He trained as a fellow in clinical research at the Multipurpose Arthritis Center, Brigham and Women’s Hospital in Boston and received a master’s degree in epidemiology from the Harvard School of Public Health.

He is a clinical researcher at the Centre de recherche du CHU de Québec-Laval University, assistant professor at Laval University’s School of Medicine. Since 2014, he has been Chief of the Rheumatology Department at the CHU de Québec-Laval University. His main research interests are rheumatoid arthritis and osteoporosis, as well as the quality of life aspects and pharmacoeconomic studies related to these diseases.

Dr. Bessette is the principal investigator of the CATCH study in Quebec City (Canadian Early Arthritis Cohort Study). CATCH is a Canadian multicentre research program that aims at improving the quality of care for people with early inflammatory arthritis. Over 2,000 people are participating in our investigator-initiated research program across Canada (100 subjects in Quebec City). This is the only Canada-wide early arthritis cohort that follows people with new onset inflammatory or rheumatoid arthritis over time to examine the course of their disease and their response to the treatments provided by their healthcare team.

He is co-investigator of the Group for Early Arthritis Research (GEAR). GEAR is a multidisciplinary team of the CHU de Québec-Laval University composed of clinicians and clinical researchers in the field of rheumatology. A model for an early arthritis clinic was put in place in 2014 to give better and earlier access to patients who suffer from rheumatic conditions. Other objectives are to collect clinical data and bio specimens on patients with early arthritis to better understand disease progression and its complications. Collecting these data and bio specimens will provide information on the population in the CHU de Québec-Laval University catchment area, and allow to elaborate strategies to improve patient care and prevent comorbid conditions in patients with early arthritis.

Dr. Bessette is co-director for the CaMOS Quebec City Centre, a large Canadian epidemiologic study in osteoporosis. He is also co-investigator of the Recognizing Osteoporosis and its Consequences in Quebec (ROCQ) Programme, a patient health-management programme aimed at evaluating the diagnostic and treatment care gaps for osteoporosis following a fragility fracture in women aged 50 years and over.

CHUL
2705, boulevard Laurier
T0-93
Québec, Québec
Canada G1V 4G2

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135 entries « 2 of 14 »

Rohekar S, Pardo Pardo J, Mirza R, Aydin SZ, Bessette L, Richard N, Mosher D, Boyd T, Chan J, Eder L, Passalent L, Karam E, Nair B, Hazlewood GS, Tse S, Rumsey D, Zummer M, Haroon N, Inman R, Gladman DD

Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Living Treatment Recommendations for the Management of Axial Spondyloarthritis

Journal Article

J Rheumatol, 2024.

Abstract | Links:

Bessette L, Florica B, Naik L, Sholter D, Fournier PA, Girard T, Liazoghli D, Baer PA

A Canadian Retrospective Chart Review Evaluating Concomitant Methotrexate De-escalation Patterns in Patients with Rheumatoid Arthritis Treated with Biologic or Targeted Synthetic DMARDs

Journal Article

Rheumatol Ther, 11 (5), 2024.

Abstract | Links:

Hadwen B, Stranges S, Pope JE, Bartlett S, Boire G, Bessette L, Hitchon CA, Hazlewood G, Keystone EC, Schieir O, Thorne C, Tin D, Valois MF, Bykerk V, Barra L,

Risk factors for prevalent and incident hypertension in rheumatoid arthritis: data from the Canadian Early Arthritis Cohort

Journal Article

Rheumatol Adv Pract, 8 (2), 2024.

Abstract | Links:

Movahedi M, Choquette D, Coupal L, Keystone E, Bombardier C, Bessette L

Impact of anti-rheumatic treatment on the individual components of the ACR composite score in patients with rheumatoid arthritis: real-world data

Journal Article

Clin Exp Rheumatol, 42 (9), 2024.

Abstract | Links:

Ramiro S, Lukas C, Bessette L, Wickersham P, Panni T, Bolce R, Liu-Leage S, Janos B, Nissen MJ, Wei JC

Early clinical response associates with long-term outcomes with ixekizumab in radiographic axial spondyloarthritis

Journal Article

RMD Open, 10 (3), 2024.

Abstract | Links:

Bessette L, Rahman P, Kelsall J, Purvis J, Rampakakis E, Lehman AJ, Rachich M, Nantel F, Asin-Milan O, Marrache AM

Real-World Incidence and Determinants of Infection in Patients With Rheumatoid Arthritis Treated With Golimumab After a Median Follow-Up Time of 27 Months

Journal Article

J Rheumatol, 50 (9), 2023.

Abstract | Links:

Maksymowych WP, Inman RD, Bessette L, Rahman P, Rampakakis E, Asin-Milan O, Rachich M, Marrache AM, Lehman AJ

Sustained low functional impairment in axial spondyloarthritis (axSpA): which are the primary outcomes that should be targeted to achieve this

Journal Article

Arthritis Res Ther, 25 (1), 2023.

Abstract | Links:

Bessette L, Kinch CD

Drs. Bessette and Kinch reply

Journal Article

J Rheumatol, 50 (4), 2023.

| Links:

Bartlett SJ, Bykerk VP, Schieir O, Valois MF, Pope JE, Boire G, Hitchon C, Hazlewood G, Bessette L, Keystone E, Thorne C, Tin D, Bingham CO,

"From Where I Stand": using multiple anchors yields different benchmarks for meaningful improvement and worsening in the rheumatoid arthritis flare questionnaire (RA-FQ)

Journal Article

Qual Life Res, 32 (5), 2023.

Abstract | Links:

Colmegna I, Valerio V, Amiable N, Useche M, Rampakakis E, Flamand L, Rollet-Labelle E, Bessette L, Fitzcharles MA, Hazel E, McCormack D, Michou L, Panopalis P, Langlois MA, Bernatsky S, Fortin PR

COVID-19 Vaccine in Immunosuppressed Adults with Autoimmune rheumatic Diseases (COVIAAD): safety, immunogenicity and antibody persistence at 12 months following Moderna Spikevax primary series

Journal Article

RMD Open, 9 (4), 2023.

Abstract | Links:

135 entries « 2 of 14 »
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Recently finished projects

  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-01-01 to 2022-12-31
Data provided by the Université Laval research projects registery