Dr. Line Guénette is a researcher within the Population Health and Health Best Practices Axis of the CHU of Quebec-Laval University Research Centre, as well as an Associate Professor in the Faculty of Pharmacy at Laval University. She is also a clinical pharmacist within the CIUSSS de la Capitale-Nationale. Her research program aims to identify and better understand the issues of drug use, particularly in people with diabetes and the elderly. She is also working to find efficient ways to optimize the use of medicines and to transform professional practices.

She is the recipient of a clinical investigator-junior 1 fellowship from the Fonds de la recherche Québec-Santé (FRQ-S) and of the FRQ-S/Société québécoise d’hypertension artérielle (SQHA) Jacques-de-Champlain Scholarship.

Towards a better understanding of the problems of drug use

Although there are now several effective and well-tolerated drugs to control several chronic diseases and reduce associated complications, problems of poor control are still too common. One of the most important barriers to optimal treatment of chronic diseases is the non-optimal use of drugs by patients and health professionals. The first step to optimize the use of medicines is to better understand the determinants of misuse. Dr. Guénette and her team are achieving this by using large databases of administrative data or surveys of patients and health professionals.

Optimizing the use of medicines

According to recent literature reviews, studies that evaluate the effectiveness of interventions to optimize drug use often have important methodological shortcomings. Moreover, very few of them describe in detail the applied interventions, the targeted determinants and the design of the interventions. It is therefore essential to improve research on the best ways to intervene and on the interventions most likely to be implemented in the Quebec context. It is also crucial to work towards reducing inappropriate practices and implementing new knowledge and activities with proven benefits. To achieve this, Dr. Guénette works closely with clinicians and decision-makers in clinical settings. A project to implement and evaluate the impact of pharmacists’ new activities under Bill 41 is currently underway.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
Québec, Québec
Canada G1S 4L8
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Guenette L, Gaudet M

Impact of prior authorization for asthma medications on the use of emergency health services: a retrospective cohort study among newly diagnosed patients with asthma

Journal Article

Clin Ther, 32 (5), 2010.

Abstract | Links:

Guenette L, Moisan J, Preville M, Boyer R

Measures of adherence based on self-report exhibited poor agreement with those based on pharmacy records

Journal Article

J Clin Epidemiol, 58 (9), 2005.

Abstract | Links:

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Active projects

  • Coûts des maladies cardiovasculaires et des problèmes de santé mentale attribuables aux contraintes psychosociales au travail : Une étude longitudinale de 22 ans auprès de 9 000 cols blancs., from 2016-07-01 to 2024-03-31
  • Development of Interdisciplinary Strategies to Prevent Chronic Opioid Use in Adult Trauma Patients, from 2021-04-01 to 2024-03-31
  • Développement et validation d’une technique pour l’identification et la recommandation d’outils numériques en santé aux patients pour la gestion des maladies chroniques par les pharmaciens communautaires, from 2019-11-01 to 2023-06-30
  • Optimisation de l’usage - Soins pharmaceutiques en première ligne: une communauté de pratique à l'intention des pharmaciens, from 2017-08-22 to 2023-12-01
  • Plateforme STAT, from 2022-04-01 to 2023-03-31
  • Projet GPS: Évaluation de l'impact de la réorganisation du travail en Groupe de médecine de famille (GMF) sur la Pharmacothérapie et le Soutien à l'autonomie des personnes âgées ayant un trouble neuro-cognitif majeur, from 2019-04-01 to 2023-06-30
  • Projet TRADI : Trajectoires de soins et d’adhésion aux traitements des personnes ayant un diabète, from 2023-02-08 to 2024-03-31
  • Protocole de suivi actif du traitement de la dépression par les pharmaciens communautaires, from 2020-04-01 to 2023-04-30
  • Succès en gestion de la douleur : Identifier les moments cruciaux pour tenter de les recréer, from 2021-11-11 to 2023-03-31

Recently finished projects

  • Adhésion aux recommandations nutritionnelles et à la pharmacothérapie dans le traitement du diabète de type 2 : les deux font la paire ?, from 2021-07-08 to 2022-03-31
  • Case management in primary care for frequent users of healthcare services with chronic diseases and complex care needs: implementation and realist evaluations, from 2018-01-01 to 2021-12-31
  • Définition et validation d'algorithmes de détection des cas de dépression et d'anxiété à l'aide des banques de données médico-administratives (MED-ECHO et RAMQ) du Québec pour les personnes âgées de 65 ans et plus, from 2020-04-01 to 2021-03-31
  • La santé mentale chez des personnes âgées atteintes de diabète de type 2 ou d'hypertension au Québec: dépression, anxiété, déclin cognitif et adhésion aux traitements, from 2019-04-01 to 2021-03-31
  • Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast, from 2019-10-01 to 2023-03-01
Data provided by the Université Laval research projects registery