Dr. Line Guénette is a researcher within the Population Health and Health Best Practices Axis of the CHU of Quebec-Laval University Research Centre, as well as an Associate Professor in the Faculty of Pharmacy at Laval University. She is also a clinical pharmacist within the CIUSSS de la Capitale-Nationale. Her research program aims to identify and better understand the issues of drug use, particularly in people with diabetes and the elderly. She is also working to find efficient ways to optimize the use of medicines and to transform professional practices.

She is the recipient of a clinical investigator-junior 1 fellowship from the Fonds de la recherche Québec-Santé (FRQ-S) and of the FRQ-S/Société québécoise d’hypertension artérielle (SQHA) Jacques-de-Champlain Scholarship.

Towards a better understanding of the problems of drug use

Although there are now several effective and well-tolerated drugs to control several chronic diseases and reduce associated complications, problems of poor control are still too common. One of the most important barriers to optimal treatment of chronic diseases is the non-optimal use of drugs by patients and health professionals. The first step to optimize the use of medicines is to better understand the determinants of misuse. Dr. Guénette and her team are achieving this by using large databases of administrative data or surveys of patients and health professionals.

Optimizing the use of medicines

According to recent literature reviews, studies that evaluate the effectiveness of interventions to optimize drug use often have important methodological shortcomings. Moreover, very few of them describe in detail the applied interventions, the targeted determinants and the design of the interventions. It is therefore essential to improve research on the best ways to intervene and on the interventions most likely to be implemented in the Quebec context. It is also crucial to work towards reducing inappropriate practices and implementing new knowledge and activities with proven benefits. To achieve this, Dr. Guénette works closely with clinicians and decision-makers in clinical settings. A project to implement and evaluate the impact of pharmacists’ new activities under Bill 41 is currently underway.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
J1-08
Québec, Québec
Canada G1S 4L8
99 entries « 6 of 10 »

Leclerc J, Blais C, Rochette L, Hamel D, Guenette L, Poirier P

Trends in Hospital Visits for Generic and Brand-Name Warfarin Users in Québec, Canada: A Population-Based Time Series Analysis

Journal Article

Am J Cardiovasc Drugs, 19 (3), 2019.

Abstract | Links:

Guénette L, Dossa R, Turcotte V, Bernard-Fortin ME, Chagnon A

Lisibilité des réponses données par des pharmaciens à des patients et publiées sur le site Internet Question pour un pharmacien

Journal Article

Pharmactuel, 52 (2), 2019.

Leclerc J, Blais C, Rochette L, Hamel D, Guenette L, Poirier P

Did Generic Clopidogrel Commercialization Affect Trends of ER Consultations and Hospitalizations in the Population Treated with Clopidogrel?

Journal Article

Drugs Aging, 36 (8), 2019.

Abstract | Links:

Maheu A, Vanier MC, Rouleau L, Dugre N, Guenette L

The Creation of a Practice-Based Network of Pharmacists Working in Family Medicine Groups (FMG)

Journal Article

Pharmacy (Basel), 7 (3), 2019.

Abstract | Links:

Sirois C, Domingues NS, Laroche ML, Zongo A, Lunghi C, Guénette L, Kröger E, Émond V

Polypharmacy Definitions for Multimorbid Older Adults Need Stronger Foundations to Guide Research, Clinical Practice and Public Health

Journal Article

Pharmacy (Basel), 7 (3), 2019.

Abstract | Links:

Trudel X, Gilbert-Ouimet M, Milot A, Duchaine CS, Vezina M, Laurin D, Sultan-Taieb H, Brisson C, , ,

Cohort Profile: The PROspective Québec (PROQ) Study on Work and Health

Journal Article

Int J Epidemiol, 47 (3), 2018.

| Links:

Chartrand M, Lalonde L, Cantin A, Lahaie A, Odobasic B, Tremblay MP, Wazzan D, Gagnon MM, Martin E, Dorais M, Berbiche D, Guenette L

Anticoagulation management services in community pharmacy: Feasibility of implementing a quality improvement programme through a practice-based research network

Journal Article

J Clin Pharm Ther, 43 (6), 2018.

Abstract | Links:

Hudon C, Chouinard MC, Aubrey-Bassler K, Burge F, Doucet S, Ramsden VR, Brodeur M, Bush PL, Couturier Y, Dubois MF, Guenette L, Legare F, Morin P, Poder TG, Poitras ME, Roberge P, Valaitis R, Bighead S, Campbell C, Couture M, Davis B, Deschenes E, Edwards L, Gander S, Gauthier G, Gauthier P, Gibson RJ, Godbout J, Landry G, Longjohn C, Rabbitskin N, Roy DA, Roy J, Sabourin V, Sampalli T, Saulnier A, Spence C, Splane J, Warren M, Young J, Pluye P

Case management in primary care for frequent users of healthcare services with chronic diseases and complex care needs: an implementation and realist evaluation protocol

Journal Article

BMJ Open, 8 (11), 2018.

Abstract | Links:

Reynolds E, Guenette L, Lexchin J, Cassels A, Wilkes MS, Durrieu G, Beaulieu MD, Mintzes B

Reconciling a "pleasant exchange" with evidence of information bias: A three-country study on pharmaceutical sales visits in primary care

Journal Article

Health Policy, 122 (3), 2018.

Abstract | Links:

Adouni Lawani M, Zongo F, Breton MC, Moisan J, Gregoire JP, Dorval E, Boulet LP, Jobin FM, Guenette L

Factors associated with adherence to asthma treatment with inhaled corticosteroids: A cross-sectional exploratory study

Journal Article

J Asthma, 55 (3), 2018.

Abstract | Links:

99 entries « 6 of 10 »
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Active projects

  • Coûts des maladies cardiovasculaires et des problèmes de santé mentale attribuables aux contraintes psychosociales au travail : Une étude longitudinale de 22 ans auprès de 9 000 cols blancs., from 2016-07-01 to 2025-03-31
  • Déprescription des gabapentinoïdes: approches et perception des personnes vivant avec de la douleur, from 2024-03-01 to 2025-03-31
  • Développement et validation d’une technique pour l’identification et la recommandation d’outils numériques en santé aux patients pour la gestion des maladies chroniques par les pharmaciens communautaires, from 2019-11-01 to 2024-06-30
  • Optimisation de l’usage - Soins pharmaceutiques en première ligne: une communauté de pratique à l'intention des pharmaciens, from 2017-08-22 to 2025-03-31
  • Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast, from 2019-10-01 to 2025-03-31
  • Plateforme STAT, from 2022-04-01 to 2025-03-31
  • Projet GPS: Évaluation de l'impact de la réorganisation du travail en Groupe de médecine de famille (GMF) sur la Pharmacothérapie et le Soutien à l'autonomie des personnes âgées ayant un trouble neuro-cognitif majeur, from 2019-04-01 to 2025-03-31
  • Projet TRADI : Trajectoires de soins et d’adhésion aux traitements des personnes ayant un diabète, from 2023-02-08 to 2025-03-31
  • Usage d'analgésiques en conditions réelles de pratique chez les personnes vivant avec de la douleur chronique : Une approche novatrice de modélisation de la polypharmacie sous forme de trajectoires de risque, from 2021-10-01 to 2026-09-30

Recently finished projects

  • Development of Interdisciplinary Strategies to Prevent Chronic Opioid Use in Adult Trauma Patients, from 2021-04-01 to 2024-03-31
  • La collaboration entre les pharmaciens GMF et communautaires, les médecins de famille et infirmières des GMF pour soutenir l’autonomie des aînés ayant des troubles cognitifs, from 2023-05-01 to 2024-04-30
  • La part du traitement de la douleur chronique non ancéreuse d’origine musculosquelettique parmi les indications cliniques de nouvelles ordonnances d’opioïdes au Québec , from 2021-04-01 to 2024-03-31
  • Protocole de suivi actif du traitement de la dépression par les pharmaciens communautaires, from 2020-04-01 to 2023-04-30
  • Succès en gestion de la douleur : Identifier les moments cruciaux pour tenter de les recréer, from 2021-11-11 to 2023-03-31
Data provided by the Université Laval research projects registery