Dr. Line Guénette is a researcher within the Population Health and Health Best Practices Axis of the CHU of Quebec-Laval University Research Centre, as well as an Associate Professor in the Faculty of Pharmacy at Laval University. She is also a clinical pharmacist within the CIUSSS de la Capitale-Nationale. Her research program aims to identify and better understand the issues of drug use, particularly in people with diabetes and the elderly. She is also working to find efficient ways to optimize the use of medicines and to transform professional practices.

She is the recipient of a clinical investigator-junior 1 fellowship from the Fonds de la recherche Québec-Santé (FRQ-S) and of the FRQ-S/Société québécoise d’hypertension artérielle (SQHA) Jacques-de-Champlain Scholarship.

Towards a better understanding of the problems of drug use

Although there are now several effective and well-tolerated drugs to control several chronic diseases and reduce associated complications, problems of poor control are still too common. One of the most important barriers to optimal treatment of chronic diseases is the non-optimal use of drugs by patients and health professionals. The first step to optimize the use of medicines is to better understand the determinants of misuse. Dr. Guénette and her team are achieving this by using large databases of administrative data or surveys of patients and health professionals.

Optimizing the use of medicines

According to recent literature reviews, studies that evaluate the effectiveness of interventions to optimize drug use often have important methodological shortcomings. Moreover, very few of them describe in detail the applied interventions, the targeted determinants and the design of the interventions. It is therefore essential to improve research on the best ways to intervene and on the interventions most likely to be implemented in the Quebec context. It is also crucial to work towards reducing inappropriate practices and implementing new knowledge and activities with proven benefits. To achieve this, Dr. Guénette works closely with clinicians and decision-makers in clinical settings. A project to implement and evaluate the impact of pharmacists’ new activities under Bill 41 is currently underway.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
J1-08
Québec, Québec
Canada G1S 4L8
+1 418-525-4444, extension 84694
+1 418-682-7962
Line.Guenette@crchudequeb... line.guenette@pha.ulaval....

Latest news

85 entries « ‹ 6 of 9 › »

Dossa AR, Moisan J, Guénette L, Lauzier S, Grégoire JP

Association between interpersonal continuity of care and medication adherence in type 2 diabetes: an observational cohort study

Journal Article

CMAJ Open, 5 (2), 2017.

Abstract | Links:

Sirois C, Laroche ML, Guénette L, Kröger E, Cooper D, Émond V

Polypharmacy in multimorbid older adults: protocol for a systematic review

Journal Article

Syst Rev, 6 (1), 2017.

Abstract | Links:

Hudon C, Chouinard MC, Aubrey-Bassler K, Muhajarine N, Burge F, Pluye P, Bush PL, Ramsden VR, Legare F, Guenette L, Morin P, Lambert M, Groulx A, Couture M, Campbell C, Baker M, Edwards L, Sabourin V, Spence C, Gauthier G, Warren M, Godbout J, Davis B, Rabbitskin N

Case management in primary care among frequent users of healthcare services with chronic conditions: protocol of a realist synthesis

Journal Article

BMJ Open, 7 (9), 2017.

Abstract | Links:

Leclerc J, Blais C, Rochette L, Hamel D, Guénette L, Poirier P

Impact of the Commercialization of Three Generic Angiotensin II Receptor Blockers on Adverse Events in Quebec, Canada: A Population-Based Time Series Analysis

Journal Article

Circ Cardiovasc Qual Outcomes, 10 (10), 2017.

Abstract | Links:

Lunghi C, Moisan J, Gregoire JP, Guenette L

The Association between Depression and Medication Nonpersistence in New Users of Antidiabetic Drugs

Journal Article

Value Health, 20 (6), 2017.

Abstract | Links:

Zomahoun HT, Guenette L, Gregoire JP, Lauzier S, Lawani AM, Ferdynus C, Huiart L, Moisan J

Effectiveness of motivational interviewing interventions on medication adherence in adults with chronic diseases: a systematic review and meta-analysis

Journal Article

Int J Epidemiol, 46 (2), 2017.

Abstract | Links:

Lunghi C, Zongo A, Moisan J, Gregoire JP, Guenette L

The impact of incident depression on medication adherence in patients with type 2 diabetes

Journal Article

Diabetes Metab, 43 (6), 2017.

Abstract | Links:

Guenette L, Zongo A, Guillaumie L, Lauzier S, Blais L, Gregoire JP, Moisan J

Psychosocial determinants of non-adherence to antidiabetic drug treatment: A prospective cohort study

Journal Article

Diabetes Metab, 43 (4), 2017.

| Links:

Lunghi C, Zongo A, Moisan J, Gregoire JP, Guenette L

Factors associated with antidiabetic medication non-adherence in patients with incident comorbid depression

Journal Article

J Diabetes Complications, 31 (7), 2017.

Abstract | Links:

Trudel X, Trudel X, Milot A, Gilbert-Ouimet M, Duchaine C, Guénette L, Dalens V, Brisson C

Effort-Reward Imbalance at Work and the Prevalence of Unsuccessfully Treated Hypertension Among White-Collar Workers

Journal Article

Am J Epidemiol, 186 (4), 2017.

Abstract | Links:

85 entries « ‹ 6 of 9 › »
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Active projects

  • Coûts des maladies cardiovasculaires et des problèmes de santé mentale attribuables aux contraintes psychosociales au travail : Une étude longitudinale de 22 ans auprès de 9 000 cols blancs., from 2016-07-01 to 2024-03-31
  • Development of Interdisciplinary Strategies to Prevent Chronic Opioid Use in Adult Trauma Patients, from 2021-04-01 to 2024-03-31
  • Développement et validation d’une technique pour l’identification et la recommandation d’outils numériques en santé aux patients pour la gestion des maladies chroniques par les pharmaciens communautaires, from 2019-11-01 to 2023-06-30
  • La collaboration entre les pharmaciens GMF et communautaires, les médecins de famille et infirmières des GMF pour soutenir l’autonomie des aînés ayant des troubles cognitifs, from 2023-05-01 to 2024-04-30
  • La part du traitement de la douleur chronique non ancéreuse d’origine musculosquelettique parmi les indications cliniques de nouvelles ordonnances d’opioïdes au Québec , from 2021-04-01 to 2024-03-31
  • Optimisation de l’usage - Soins pharmaceutiques en première ligne: une communauté de pratique à l'intention des pharmaciens, from 2017-08-22 to 2023-12-01
  • Projet GPS: Évaluation de l'impact de la réorganisation du travail en Groupe de médecine de famille (GMF) sur la Pharmacothérapie et le Soutien à l'autonomie des personnes âgées ayant un trouble neuro-cognitif majeur, from 2019-04-01 to 2024-03-31
  • Projet TRADI : Trajectoires de soins et d’adhésion aux traitements des personnes ayant un diabète, from 2023-02-08 to 2024-03-31
  • Usage d'analgésiques en conditions réelles de pratique chez les personnes vivant avec de la douleur chronique : Une approche novatrice de modélisation de la polypharmacie sous forme de trajectoires de risque, from 2021-10-01 to 2026-09-30

Recently finished projects

  • Adhésion aux recommandations nutritionnelles et à la pharmacothérapie dans le traitement du diabète de type 2 : les deux font la paire ?, from 2021-07-08 to 2022-03-31
  • Case management in primary care for frequent users of healthcare services with chronic diseases and complex care needs: implementation and realist evaluations, from 2018-01-01 to 2021-12-31
  • Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast, from 2019-10-01 to 2023-03-01
  • Plateforme STAT, from 2022-04-01 to 2023-03-31
  • Protocole de suivi actif du traitement de la dépression par les pharmaciens communautaires, from 2020-04-01 to 2023-04-30
  • Succès en gestion de la douleur : Identifier les moments cruciaux pour tenter de les recréer, from 2021-11-11 to 2023-03-31
Data provided by the Université Laval research projects registery