Dr. Line Guénette is a researcher within the Population Health and Health Best Practices Axis of the CHU of Quebec-Laval University Research Centre, as well as an Associate Professor in the Faculty of Pharmacy at Laval University. She is also a clinical pharmacist within the CIUSSS de la Capitale-Nationale. Her research program aims to identify and better understand the issues of drug use, particularly in people with diabetes and the elderly. She is also working to find efficient ways to optimize the use of medicines and to transform professional practices.

She is the recipient of a clinical investigator-junior 1 fellowship from the Fonds de la recherche Québec-Santé (FRQ-S) and of the FRQ-S/Société québécoise d’hypertension artérielle (SQHA) Jacques-de-Champlain Scholarship.

Towards a better understanding of the problems of drug use

Although there are now several effective and well-tolerated drugs to control several chronic diseases and reduce associated complications, problems of poor control are still too common. One of the most important barriers to optimal treatment of chronic diseases is the non-optimal use of drugs by patients and health professionals. The first step to optimize the use of medicines is to better understand the determinants of misuse. Dr. Guénette and her team are achieving this by using large databases of administrative data or surveys of patients and health professionals.

Optimizing the use of medicines

According to recent literature reviews, studies that evaluate the effectiveness of interventions to optimize drug use often have important methodological shortcomings. Moreover, very few of them describe in detail the applied interventions, the targeted determinants and the design of the interventions. It is therefore essential to improve research on the best ways to intervene and on the interventions most likely to be implemented in the Quebec context. It is also crucial to work towards reducing inappropriate practices and implementing new knowledge and activities with proven benefits. To achieve this, Dr. Guénette works closely with clinicians and decision-makers in clinical settings. A project to implement and evaluate the impact of pharmacists’ new activities under Bill 41 is currently underway.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
J1-08
Québec, Québec
Canada G1S 4L8
99 entries « 1 of 10 »

D'Aiuto C, Lunghi C, Guénette L, Berbiche D, Bertrand K, Vasiliadis HM

Risk of Mortality Associated with Potentially Inappropriate Medication Use Including Opioids in Older Adults

Journal Article

Drug Saf, 2024.

Abstract | Links:

Assan O, Memoli V, Guillaumie L, Turcotte V, Lemay M, Dionne A, Lemieux J, Provencher L, Gotay C, de Bruin M, Guénette L, Lauzier S

Pilot randomized controlled trial of a program to enhance experience and adherence with adjuvant endocrine therapy among women with non-metastatic breast cancer: 12-month quantitative results

Journal Article

J Cancer Surviv, 2024.

Abstract | Links:

Godbout-Parent M, Julien N, Nguena Nguefack HL, Pagé MG, Guénette L, Blais L, Beaudoin S, Bertrand C, Lacasse A

Changing society, changing research: integrating gender to better understand physical and psychological treatments use in chronic pain management

Journal Article

Pain, 165 (3), 2024.

Abstract | Links:

De Clifford-Faugère G, Nguena Nguefack HL, Godbout-Parent M, Diallo MA, Guénette L, Gabrielle Pagé M, Choinière M, Harden RN, Beaudoin S, Boulanger A, Pinard AM, Lussier D, De Grandpré P, Deslauriers S, Lacasse A

The Medication Quantification Scale 4.0: An Updated Index Based on Prescribers' Perceptions of the Risk Associated With Chronic Pain Medications

Journal Article

J Pain, 25 (2), 2024.

Abstract | Links:

Desjardins C, Leblay L, Bélanger A, Filiatrault M, Barbier O, Guénette L, Leclerc J, Lefebvre J, Zongo A, Drouin-Chartier JP

Relationship Between Diet Quality and Glucose-Lowering Medication Intensity Among Adults With Type 2 Diabetes: Results From the CARTaGENE Cohort

Journal Article

CJC Open, 6 (1), 2024.

Abstract | Links:

Audet C, Zerriouh M, Nguena Nguefack HL, Julien N, Pagé MG, Guénette L, Blais L, Lacasse A

Where we live matters: a comparison of chronic pain treatment between remote and non-remote regions of Quebec, Canada

Journal Article

Front Pain Res (Lausanne), 5 , 2024.

Abstract | Links:

Zerriouh M, De Clifford-Faugère G, Nguena Nguefack HL, Pagé MG, Guénette L, Blais L, Lacasse A

Pain relief and associated factors: a cross-sectional observational web-based study in a Quebec cohort of persons living with chronic pain

Journal Article

Front Pain Res (Lausanne), 5 , 2024.

Abstract | Links:

Duncan P, Scott LJ, Dawson S, Munas M, Pyne Y, Chaplin K, Gaunt D, Guenette L, Salisbury C

Further development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ)

Journal Article

BMJ Open, 14 (4), 2024.

Abstract | Links:

Attisso E, Guenette L, Dionne CE, Kröger E, Dialahy I, Tessier S, Jean S

New opioid prescription claims and their clinical indications: results from health administrative data in Quebec, Canada, over 14 years

Journal Article

BMJ Open, 14 (4), 2024.

Abstract | Links:

Pitrou I, D'Aiuto C, Lunghi C, Guénette L, Berbiche D, Bertrand K, Vasiliadis HM

Changes in self-rated physical and mental health and life satisfaction associated with opioid and potentially inappropriate opioid prescribing in primary care older adults

Journal Article

Fam Pract, 2023.

Abstract | Links:

99 entries « 1 of 10 »
Signaler des ajouts ou des modifications

Active projects

  • Coûts des maladies cardiovasculaires et des problèmes de santé mentale attribuables aux contraintes psychosociales au travail : Une étude longitudinale de 22 ans auprès de 9 000 cols blancs., from 2016-07-01 to 2025-03-31
  • Déprescription des gabapentinoïdes: approches et perception des personnes vivant avec de la douleur, from 2024-03-01 to 2025-03-31
  • Développement et validation d’une technique pour l’identification et la recommandation d’outils numériques en santé aux patients pour la gestion des maladies chroniques par les pharmaciens communautaires, from 2019-11-01 to 2024-06-30
  • Optimisation de l’usage - Soins pharmaceutiques en première ligne: une communauté de pratique à l'intention des pharmaciens, from 2017-08-22 to 2025-03-31
  • Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast, from 2019-10-01 to 2025-03-31
  • Plateforme STAT, from 2022-04-01 to 2025-03-31
  • Projet GPS: Évaluation de l'impact de la réorganisation du travail en Groupe de médecine de famille (GMF) sur la Pharmacothérapie et le Soutien à l'autonomie des personnes âgées ayant un trouble neuro-cognitif majeur, from 2019-04-01 to 2025-03-31
  • Projet TRADI : Trajectoires de soins et d’adhésion aux traitements des personnes ayant un diabète, from 2023-02-08 to 2025-03-31
  • Usage d'analgésiques en conditions réelles de pratique chez les personnes vivant avec de la douleur chronique : Une approche novatrice de modélisation de la polypharmacie sous forme de trajectoires de risque, from 2021-10-01 to 2026-09-30

Recently finished projects

  • Development of Interdisciplinary Strategies to Prevent Chronic Opioid Use in Adult Trauma Patients, from 2021-04-01 to 2024-03-31
  • La collaboration entre les pharmaciens GMF et communautaires, les médecins de famille et infirmières des GMF pour soutenir l’autonomie des aînés ayant des troubles cognitifs, from 2023-05-01 to 2024-04-30
  • La part du traitement de la douleur chronique non ancéreuse d’origine musculosquelettique parmi les indications cliniques de nouvelles ordonnances d’opioïdes au Québec , from 2021-04-01 to 2024-03-31
  • Protocole de suivi actif du traitement de la dépression par les pharmaciens communautaires, from 2020-04-01 to 2023-04-30
  • Succès en gestion de la douleur : Identifier les moments cruciaux pour tenter de les recréer, from 2021-11-11 to 2023-03-31
Data provided by the Université Laval research projects registery