Dr. Michou completed her medical studies at l’Université d’Angers, her Rheumatology residency at l’Université Denis-Diderot-Paris VII and her PhD in Human Genetics at l’Université René-Descartes-Paris V (France). She had in parallel completed a two-year clinical fellowship in fragility bone diseases at the centre Viggo Petersen, Rheumatology department, Lariboisière hospital, Assistance publique-Hôpitaux de Paris, France.

Dr Michou is a clinical investigator at the Centre de Recherche du CHU de Québec-Laval University, rheumatologist at the CHUL, and associate professor at Laval University’s School of Medicine, Quebec. Dr Michou is the principal investigator of several academic research projects in the field of rheumatic diseases, mainly funded by the Fonds de recherche du Québec-Santé, Canadian Institutes of Health research, the Arthritis Society, and the CHU de Québec foundation. She supervises master and PhD students, as well as the clinical research projects of rheumatology and internal medicine residents.

She is the author or coauthor of 53 scientific refereed articles, over  100 oral or poster communications in scientific congresses, and approximately 30 articles of continuing medical education for rheumatologists or family doctors.

Dr. Michou’s research interests are human genetics of bone and joint diseases, particularly Paget’s disease of the bone, rare bone diseases, osteoporosis, Dupuytren’s disease and rheumatoid arthritis. She is the manager of the Biobank and Bank of Data for the Study of Heritable Musculoskeletal Diseases and co-manager of the Biobank and Repository Data for Systemic Autoimmune Rheumatic Diseases.

CHUL
2705, boulevard Laurier
T0-83
Québec, Québec
Canada G1V 4G2

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69 entries « 2 of 7 »

Michou L, Orcel P

Has Paget's bone disease become rare?

Journal Article

Joint Bone Spine, 86 (5), 2019.

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Numan MS, Jean S, Dessay M, Gagnon E, Amiable N, Brown JP, Michou L

Gene-environment interactions in Paget's disease of bone

Journal Article

Joint Bone Spine, 86 (3), 2019.

Abstract | Links:

Veyssiere M, Perea J, Michou L, Boland A, Caloustian C, Olaso R, Deleuze JF, Cornelis F, Petit-Teixeira E, Chaudru V

A novel nonsense variant in SUPT20H gene associated with Rheumatoid Arthritis identified by Whole Exome Sequencing of multiplex families

Journal Article

PLoS One, 14 (3), 2019.

Abstract | Links:

Nadon V, Molto A, Etcheto A, Bessette L, Michou L, D'Agostino MA, Claudepierre P, Wendling D, Haraoui P, Dougados M

Clinical peripheral enthesitis in the DESIR prospective longitudinal axial spondyloarthritis cohort

Journal Article

Clin Exp Rheumatol, 37 (4), 2019.

Abstract | Links:

Leclerc JT, Michou L, Vaillancourt F, Pelet S, Simonyan D, Belzile EL

Prevalence and Characteristics of Atypical Periprosthetic Femoral Fractures

Journal Article

J Bone Miner Res, 34 (1), 2019.

Abstract | Links:

Paccou J, Michou L, Kolta S, Debiais F, Cortet B, Guggenbuhl P

High bone mass in adults

Journal Article

Joint Bone Spine, 85 (6), 2018.

Abstract | Links:

Michou L

Epigenetics of bone diseases

Journal Article

Joint Bone Spine, 85 (6), 2018.

Abstract | Links:

Silva IAL, Conceicao N, Gagnon E, Brown JP, Cancela ML, Michou L

Molecular effect of an OPTN common variant associated to Paget's disease of bone

Journal Article

PLoS One, 13 (5), 2018.

Abstract | Links:

Nguyen P, Julien AS, Bessette L, Fortin PR, Michou L

Sharing Ongoing Care with Primary Care Physicians Opens Up Opportunity for Timelier and Earlier Care by Rheumatologists for Patients with New Inflammatory Polyarthritis

Journal Article

J Rheumatol, 45 (2), 2018.

Abstract | Links:

Silva IAL, Conceicao N, Gagnon E, Caiado H, Brown JP, Gianfrancesco F, Michou L, Cancela ML

Effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone

Journal Article

Biochim Biophys Acta Mol Basis Dis, 1864 (1), 2018.

Abstract | Links:

69 entries « 2 of 7 »
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Active projects

  • Clinical validity and clinical utility of a screening test for Paget's disease of bone, from 2019-03-01 to 2023-03-31
  • Multifaceted Intervention using Telehealth to Reduce the risk of Falls and Fractures in Older Men (MisterFit study): a Pilot Study , from 2021-10-01 to 2025-09-30
  • Rôle de SUPT20H dans la pathogénie de la polyarthrite rhumatoïde, from 2022-03-10 to 2023-02-28

Recently finished projects

  • Caractérisation de biomarqueurs pour une médecine de précision en rhumatologie, from 2017-07-01 to 2021-06-30
  • Développement d'un cours en ligne accrédité sur la médecine de précision destiné aux rhumatologues et résidents en rhumatologie de la province de Québec, from 2020-09-09 to 2021-03-31
  • Financement d'un projet de recherche clinique en rhumatologie, from 2020-07-20 to 2021-03-31
  • Financement pour projet de recherche clinique en rhumatologie, mai 2020, from 2020-05-14 to 2022-03-31
  • Impact fonctionnel d’un variant rare du gène WNT1 en présence de bisphosphonates in vitro dans les trois principaux types de cellules osseuses, from 2021-09-08 to 2022-03-31
  • Support of Rheumatic Health Units Competition, from 2016-09-01 to 2020-08-31
Data provided by the Université Laval research projects registery