Dr. Michou completed her medical studies at l’Université d’Angers, her Rheumatology residency at l’Université Denis-Diderot-Paris VII and her PhD in Human Genetics at l’Université René-Descartes-Paris V (France). She had in parallel completed a two-year clinical fellowship in fragility bone diseases at the centre Viggo Petersen, Rheumatology department, Lariboisière hospital, Assistance publique-Hôpitaux de Paris, France.
Dr Michou is a clinical investigator at the Centre de Recherche du CHU de Québec-Laval University, rheumatologist at the CHUL, and associate professor at Laval University’s School of Medicine, Quebec. Dr Michou is the principal investigator of several academic research projects in the field of rheumatic diseases, mainly funded by the Fonds de recherche du Québec-Santé, Canadian Institutes of Health research, the Arthritis Society, and the CHU de Québec foundation. She supervises master and PhD students, as well as the clinical research projects of rheumatology and internal medicine residents.
She is the author or coauthor of 53 scientific refereed articles, over 100 oral or poster communications in scientific congresses, and approximately 30 articles of continuing medical education for rheumatologists or family doctors.
Dr. Michou’s research interests are human genetics of bone and joint diseases, particularly Paget’s disease of the bone, rare bone diseases, osteoporosis, Dupuytren’s disease and rheumatoid arthritis. She is the manager of the Biobank and Bank of Data for the Study of Heritable Musculoskeletal Diseases and co-manager of the Biobank and Repository Data for Systemic Autoimmune Rheumatic Diseases.
2705, boulevard Laurier
T0-83
Québec, Québec
Canada G1V 4G2
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- Audet, DanaéInternCHUL+1 418-525-4444, extension 42296
2705, boulevard Laurier
R-4720
Québec, QC
Canada G1V 4G2 - Gagnon, ÉdithEmployeeCHUL+1 418-525-4444, extension 42296 / 48236+1 418-654-2142Edith-R.Gagnon@crchudequebec.ulaval.ca
2705, boulevard Laurier
R-4720
Québec, Québec
Canada G1V 4G2 - Kamla Wamba, LambertMaster studentlambert.kamla-wamba@crchudequebec.ulaval.ca
- Paré, GuillaumeEmployeeCHUL+1 418-525-4444, extension 42296 / 47043guillaume.pare@crchudequebec.ulaval.ca
2705, boulevard Laurier
T1-49
Québec, Québec
Canada G1V 4G2
Prevalence and incidence of Paget's disease of bone: Temporal trend over 20 years in the province of Quebec, Canada
Journal ArticleBone, 176 , 2023.
Molecular test of Paget's disease of bone in families not linked to SQSTM1 gene mutations
Journal ArticleBone Rep, 18 , 2023.
Decline in clinical severity of Paget's disease of bone: Comparison between a contemporary cohort and a historical cohort
Journal ArticleBone, 170 , 2023.
Measuring the impact of an educational intervention in rheumatoid arthritis: An open-label, randomized trial
Journal ArticleArch Rheumatol, 37 (2), 2022.
Attenuated clinical and osteoclastic phenotypes of Paget's disease of bone linked to the p.Pro392Leu/SQSTM1 mutation by a rare variant in the DOCK6 gene
Journal ArticleBMC Med Genomics, 15 (1), 2022.
Prevalence of Vertebral Fractures in Adults With Type 1 Diabetes: DenSiFy Study (Diabetes Spine Fractures)
Journal ArticleJ Clin Endocrinol Metab, 107 (5), 2022.
Expectations and educational needs of rheumatologists, rheumatology fellows and patients in the field of precision medicine in Canada, a quantitative cross-sectional and descriptive study
Journal ArticleBMC Rheumatol, 5 (1), 2021.
Expression of the myeloid inhibitory receptor CLEC12A correlates with disease activity and cytokines in early rheumatoid arthritis
Journal ArticleSci Rep, 11 (1), 2021.
Duration-Dependent Increase of Human Bone Matrix Mineralization in Long-Term Bisphosphonate Users with Atypical Femur Fracture
Journal ArticleJ Bone Miner Res, 36 (6), 2021.
Clinical phenotype of adult offspring carriers of the p.Pro392Leu mutation within the SQSTM1 gene in Paget's disease of bone
Journal ArticleBone Rep, 13 , 2020.
Active projects
- Facteurs de risque associés à la résistance à de multiples agents biologiques dans la polyarthrite rhumatoïde et l'arthrite psoriasique périphérique, from 2020-05-14 to 2024-03-31
- Multifaceted Intervention using Telehealth to Reduce the risk of Falls and Fractures in Older Men (MisterFit study): a Pilot Study , from 2021-10-01 to 2025-09-30
- Transgenic rats overexpressing HDAC9 to explore the missing link between osteoporosis and vascular disease in chronic kidney disease, from 2023-06-21 to 2024-03-31
Recently finished projects
- Clinical validity and clinical utility of a screening test for Paget's disease of bone, from 2019-03-01 to 2023-03-31
- Impact fonctionnel d’un variant rare du gène WNT1 en présence de bisphosphonates in vitro dans les trois principaux types de cellules osseuses, from 2021-09-08 to 2022-03-31
- Rôle de SUPT20H dans la pathogénie de la polyarthrite rhumatoïde, from 2022-03-10 to 2023-02-28