Dr. St-Amand completed his doctoral studies at Laval University, and his postdoctoral studies at the University of British Columbia. In 1998, he optimized the SAGE method in his laboratory located in Japan, at the pharmaceutical company Otsuka. He is currently a full professor in the Department of Molecular Medicine at Laval University, and director of the Functional Genomics Laboratory and SAGE platform at the CHU Research Centre of Quebec. He is an expert in genetic engineering and functional genomics.

Dr. St-Amand’s research program aims to characterize the transcriptomes of several tissues and their regulation through physical exercise, a lipid-rich diet, and steroid hormones, in order to identify, clone and characterize functionally the genes of interest that can be used as therapeutic targets for coronary heart disease, obesity, and cancer. Dr. St-Amand’s laboratory is developing genetic engineering methods and bioinformatics programs, particularly for the analysis of functional genomics results. Dr. St-Amand developed the first SAGE platform in Canada. This powerful strategy makes it possible to compare all transcripts, including new genes, to identify the molecular mechanisms responsible for diseases.

Dr. St-Amand and his team are also studying in vitro cells and knockout mice to characterize the functions of candidate genes. These research projects will identify therapeutic targets to, in turn, develop therapeutic treatments for obesity and cardiovascular disease.

CHUL
2705, boulevard Laurier
R-4775
Québec, Québec
Canada G1V 4G2
+1 418-525-4444, extension 46448
jonny.st-amand@crchudeque...

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82 entries « ‹ 8 of 9 › »

Ye P, Yoshioka M, Gan L, St-Amand J

Regulation of global gene expression by ovariectomy and estrogen in female adipose tissue

Journal Article

Obes Res, 13 (6), 2005.

Abstract | Links:

Yoshioka M, Ayabe M, Yahiro T, Higuchi H, Higaki Y, St-Amand J, Miyazaki H, Yoshitake Y, Shindo M, Tanaka H

Long-period accelerometer monitoring shows the role of physical activity in overweight and obesity

Journal Article

Int J Obes (Lond), 29 (5), 2005.

Abstract | Links:

St-Amand J, Tanakam H, Shono N, Snyder EE, Shindo M, Yoshioka M

SAGE Identifies Transcripts Involved in Enhanced Performance of Endurance Athlete's Muscle

Book Chapter

Wang SM (Ed.): SAGE: Current Technologies and Applications, pp. 265-280, Norfolk, England, Horizon Bioscience, 2005, ISBN: 1904933076.

Larose M, St-Amand J, Yoshioka M, Belleau P, Morissette J, Labrie C, Raymond V, Labrie F

Transcriptome of mouse uterus by serial analysis of gene expression (SAGE): comparison with skeletal muscle

Journal Article

Mol Reprod Dev, 68 (2), 2004.

Abstract | Links:

Yoshioka M, Imanaga M, Ueyama H, Yamane M, Kubo Y, Boivin A, St-Amand J, Tanaka H, Kiyonaga A

Maximum tolerable dose of red pepper decreases fat intake independently of spicy sensation in the mouth

Journal Article

Br J Nutr, 91 (6), 2004.

Abstract | Links:

Bolduc C, Larose M, Lafond N, Yoshioka M, Rodrigue MA, Morissette J, Labrie C, Raymond V, St-Amand J

Adipose tissue transcriptome by serial analysis of gene expression

Journal Article

Obes Res, 12 (5), 2004.

Abstract | Links:

Bolduc C, Larose M, Yoshioka M, Ye P, Belleau P, Labrie C, Morissette J, Raymond V, Labrie F, St-Amand J

Effects of dihydrotestosterone on adipose tissue measured by serial analysis of gene expression

Journal Article

J Mol Endocrinol, 33 (2), 2004.

Abstract | Links:

Yoshioka M, Tanaka H, Shono N, Snyder EE, Shindo M, St-Amand J

Serial analysis of gene expression in the skeletal muscle of endurance athletes compared to sedentary men

Journal Article

FASEB J, 17 (13), 2003.

Abstract | Links:

St-Amand J, Okamura K, Matsumoto K, Shimizu S, Sogawa Y

Characterization of control and immobilized skeletal muscle: an overview from genetic engineering

Journal Article

FASEB J, 15 (3), 2001.

Abstract | Links:

St-Amand J, Prud'Homme D, Moorjani S, Nadeau A, Tremblay A, Bouchard C, Lupien PJ, Després JP

Apolipoprotein E polymorphism and the relationships of physical fitness to plasma lipoprotein-lipid levels in men and women

Journal Article

Med Sci Sports Exerc, 31 (5), 1999.

Abstract | Links:

82 entries « ‹ 8 of 9 › »
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  • Roles of SPARC against muscle atrophy, sarcopenia and age-related metabolic disorders, from 2023-03-01 to 2024-02-29
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