Dr. St-Amand completed his doctoral studies at Laval University, and his postdoctoral studies at the University of British Columbia. In 1998, he optimized the SAGE method in his laboratory located in Japan, at the pharmaceutical company Otsuka. He is currently a full professor in the Department of Molecular Medicine at Laval University, and director of the Functional Genomics Laboratory and SAGE platform at the CHU Research Centre of Quebec. He is an expert in genetic engineering and functional genomics.

Dr. St-Amand’s research program aims to characterize the transcriptomes of several tissues and their regulation through physical exercise, a lipid-rich diet, and steroid hormones, in order to identify, clone and characterize functionally the genes of interest that can be used as therapeutic targets for coronary heart disease, obesity, and cancer. Dr. St-Amand’s laboratory is developing genetic engineering methods and bioinformatics programs, particularly for the analysis of functional genomics results. Dr. St-Amand developed the first SAGE platform in Canada. This powerful strategy makes it possible to compare all transcripts, including new genes, to identify the molecular mechanisms responsible for diseases.

Dr. St-Amand and his team are also studying in vitro cells and knockout mice to characterize the functions of candidate genes. These research projects will identify therapeutic targets to, in turn, develop therapeutic treatments for obesity and cardiovascular disease.

CHUL
2705, boulevard Laurier
R-4775
Québec, Québec
Canada G1V 4G2
+1 418-525-4444, extension 46448
jonny.st-amand@crchudeque...

Latest news

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Ghanemi A, Yoshioka M, St-Amand J

Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine

Journal Article

Genes (Basel), 12 (11), 2021.

Abstract | Links:

Ghanemi A, Yoshioka M, St-Amand J

Secreted Protein Acidic and Rich in Cysteine as a Molecular Physiological and Pathological Biomarker

Journal Article

Biomolecules, 11 (11), 2021.

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Ghanemi A, Yoshioka M, St-Amand J

Ageing and Obesity Shared Patterns: From Molecular Pathogenesis to Epigenetics

Journal Article

Diseases, 9 (4), 2021.

Abstract | Links:

Ghanemi A, Yoshioka M, St-Amand J

Diet Impact on Obesity beyond Calories and Trefoil Factor Family 2 (TFF2) as an Illustration: Metabolic Implications and Potential Applications

Journal Article

Biomolecules, 11 (12), 2021.

Abstract | Links:

Ghanemi A, Yoshioka M, St-Amand J

Secreted protein acidic and rich in cysteine and cancer: A homeostatic hormone?

Journal Article

Cytokine, 127 , 2020.

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Ghanemi A, Yoshioka M, St-Amand J

Secreted protein acidic and rich in cysteine and inflammation: Another homeostatic property?

Journal Article

Cytokine, 133 , 2020.

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Ghanemi A, Yoshioka M, St-Amand J

Trefoil Factor Family Member 2 (TFF2) as an Inflammatory-Induced and Anti-Inflammatory Tissue Repair Factor

Journal Article

Animals (Basel), 10 (9), 2020.

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Melouane A, Yoshioka M, St-Amand J

Extracellular matrix/mitochondria pathway: A novel potential target for sarcopenia

Journal Article

Mitochondrion, 50 , 2020.

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Ghanemi A, Yoshioka M, St-Amand J

Will an obesity pandemic replace the coronavirus disease-2019 (COVID-19) pandemic

Journal Article

Med Hypotheses, 144 , 2020.

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Ghanemi A, Yoshioka M, St-Amand J

Regeneration during Obesity: An Impaired Homeostasis

Journal Article

Animals (Basel), 10 (12), 2020.

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82 entries « ‹ 3 of 9 › »
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Recently finished projects

  • Roles of SPARC against muscle atrophy, sarcopenia and age-related metabolic disorders, from 2023-03-01 to 2024-02-29
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