Dr. Jacques Corbeil focuses on using the latest techniques in bioinformatics and machine learning to assist and facilitate the processes of diagnosis and prognosis determination and to optimize response to treatment. Modern genomic techniques generate a deluge of data that needs to be interpreted using novel bioinformatic approaches. Dr. Corbeil uses state-of-the-art instrumentation and big data analytics to facilitate the interpretation of complex phenotypic data. His research includes investigating how infectious microorganisms interact with their hosts, examining the effects of antibiotics on our microbial flora, exploring how to design small molecules and drugs to interfere with specific microbial functions and integrating omic data in cancer research. Dr. Corbeil operates at the interface of computer and omic sciences.

Dr. Corbeil completed his undergraduate work at Laval University. He obtained his Ph.D. from the University of New South Wales, Sydney, Australia, and received postdoctoral training at the University of California San Diego; continuing on as a faculty member and rising to the rank of Associate Professor until his return to Canada as holder of the Tier 1 Canada Research Chair in Medical Genomics.

CHUL
2705, boulevard Laurier
R-0709
Québec, Québec
Canada G1V 4G2
148 entries « 1 of 15 »

Gobeil É, Maltais-Payette I, Taba N, Brière F, Ghodsian N, Abner E, Bourgault J, Gagnon E, Manikpurage HD, Couture C, Mitchell PL, Mathieu P, Julien F, Corbeil J, Vohl MC, Thériault S, Esko T, Tchernof A, Arsenault BJ

Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease

Journal Article

Metabolites, 12 (5), 2022.

Abstract | Links:

Déraspe M, Boisvert S, Laviolette F, Roy PH, Corbeil J

Flexible protein database based on amino acid k-mers

Journal Article

Sci Rep, 12 (1), 2022.

Abstract | Links:

Racine É, Boivin G, Longtin Y, McCormack D, Decaluwe H, Savard P, Cheng MP, Hamelin MÈ, Carbonneau J, Tadount F, Adams K, Bourdin B, Nantel S, Gilca V, Corbeil J, De Serres G, Quach-Thanh C

The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers

Journal Article

Influenza Other Respir Viruses, 2022.

Abstract | Links:

Uyar O, Dominguez JM, Bordeleau M, Lapeyre L, Ibáñez FG, Vallières L, Tremblay ME, Corbeil J, Boivin G

Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response

Journal Article

J Neuroinflammation, 19 (1), 2022.

Abstract | Links:

Abed JY, Déraspe M, Bérubé È, D'Iorio M, Dewar K, Boissinot M, Corbeil J, Bergeron MG, Roy PH

Complete Genome Sequences of and , KPC-2-Producers Serially Isolated from a Single Patient

Journal Article

Antibiotics (Basel), 10 (11), 2021.

Abstract | Links:

Osseni MA, Tossou P, Corbeil J, Laviolette F

Applying PySCMGroup to Breast Cancer Biomarkers Discovery

Book Chapter

C, Gehin; B, Wacogne; A, Fred; H, Gamboa (Ed.): Proceedings of the 14th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2021), pp. 72-82, Setúbal, SciTePress, 2021, ISBN: 9789897584909.

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Kpanou R, Osseni MA, Tossou P, Laviolette F, Corbeil J

On the robustness of generalization of drug-drug interaction models

Journal Article

BMC Bioinformatics, 22 (1), 2021.

Abstract | Links:

Uyar O, Plante PL, Piret J, Venable MC, Carbonneau J, Corbeil J, Boivin G

A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis

Journal Article

Sci Rep, 11 (1), 2021.

Abstract | Links:

Gambino AS, Déraspe M, Álvarez VE, Quiroga MP, Corbeil J, Roy PH, Centrón D

Serratia marcescens SCH909 as reservoir and source of genetic elements related to wide dissemination of antimicrobial resistance mechanisms

Journal Article

FEMS Microbiol Lett, 368 (14), 2021.

Abstract | Links:

Sirois C, Khoury R, Durand A, Deziel PL, Bukhtiyarova O, Chiu Y, Talbot D, Bureau A, Després P, Gagné C, Laviolette F, Savard AM, Corbeil J, Badard T, Jean S, Simard M

Exploring polypharmacy with artificial intelligence: data analysis protocol

Journal Article

BMC Med Inform Decis Mak, 21 (1), 2021.

Abstract | Links:

148 entries « 1 of 15 »
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Active projects

  • Acides biliaires et maladies inflammatoires chroniques de l’intestin : et si la solution était dans l’assiette?, from 2022-03-03 to 2023-03-02
  • Antimicrobial resistance genes in bioaerosols in Canadian arctic, rural, and urban environments: sources, profiles, transport and fate, from 2019-12-01 to 2024-11-30
  • Chaire de recherche du Canada en Medical genomics, from 2018-01-01 to 2024-12-31
  • Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle, from 2020-04-01 to 2023-03-31
  • Développement d'une technologie de contrôle de la qualité des plantes en cours du procédé manufacturier de médicaments en utilisant la spectrométrie de masse à haut débit couplée à des approches en apprentissage automatique , from 2020-03-19 to 2023-03-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3, from 2019-11-01 to 2024-10-31
  • Ecogenomics of mining areas for sustainable Canadian North (GENOSCAN), from 2020-11-01 to 2024-12-31
  • Extreme zooming on intestinal permeability and the western-style diet: Unravelling the role of dietary antigens on the prevalence of cardiometabolic and mental health diseases in the North, from 2020-11-01 to 2024-12-31
  • MAchine learning for diGItal diagnosTICS of antimicrobial resistance, from 2019-10-01 to 2022-09-30
  • Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique, from 2018-04-01 to 2024-03-31
  • Prédire l'évolution de l'hépatite C par la fédération de données et l'intelligence artificielle : enjeux éthiques, juridiques, sociaux et de vie privée, from 2019-04-01 to 2023-03-31
  • Unravelling the impact of diet on cardiovascular health in heterozygous familial hypercholesterolemia: a metabolomic approach, from 2021-10-01 to 2025-09-30
  • UVILUQ: l'utilisation des biopsie liquides pour le monitoring de l'état de santé des écosystèmes marins côtiers, from 2020-07-01 to 2023-06-30

Recently finished projects

  • Advanced study of unconventional oil behaviour, innovative emergency measures to surface water oil spills: protection of water sources, from 2016-09-30 to 2020-09-29
  • Calcul Québec, from 2015-04-01 to 2022-03-31
  • Concert pour la vie, from 2020-11-13 to 2021-03-31
  • COVID19 persistent symptomatology: an investigation of the metabolomic and proteomic underpinning, from 2021-06-01 to 2022-05-31
  • Deciphering breast cancer HER2-negativity with regard to HER2-targeted therapy, from 2016-07-01 to 2021-06-30
  • La plateforme bio-environnementale EcoChip: Prototypage d'une preuve de concept robuste, from 2020-03-01 to 2021-06-01
  • Profil moléculaire sanguin de patientes souffrant de lupus, from 2019-04-01 to 2021-03-31
  • REinfection in COVid-19 Estimation of Risk (RECOVER), from 2020-06-01 to 2020-09-30
Data provided by the Université Laval research projects registery