Dr. Jacques Corbeil focuses on using the latest techniques in bioinformatics and machine learning to assist and facilitate the processes of diagnosis and prognosis determination and to optimize response to treatment. Modern genomic techniques generate a deluge of data that needs to be interpreted using novel bioinformatic approaches. Dr. Corbeil uses state-of-the-art instrumentation and big data analytics to facilitate the interpretation of complex phenotypic data. His research includes investigating how infectious microorganisms interact with their hosts, examining the effects of antibiotics on our microbial flora, exploring how to design small molecules and drugs to interfere with specific microbial functions and integrating omic data in cancer research. Dr. Corbeil operates at the interface of computer and omic sciences.

Dr. Corbeil completed his undergraduate work at Laval University. He obtained his Ph.D. from the University of New South Wales, Sydney, Australia, and received postdoctoral training at the University of California San Diego; continuing on as a faculty member and rising to the rank of Associate Professor until his return to Canada as holder of the Tier 1 Canada Research Chair in Medical Genomics.

CHUL
2705, boulevard Laurier
R-0709
Québec, Québec
Canada G1V 4G2
+1 418-525-4444, extension 46423
+1 418-654-2743
jacques.corbeil@crchudequ...

Latest news

153 entries « ‹ 1 of 16 › »

Abed JY, Godon T, Mehdaoui F, Plante PL, Boissinot M, Bergeron MG, Bélanger RE, Muckle G, Poliakova N, Ayotte P, Corbeil J, Rousseau E

Gut metagenome profile of the Nunavik Inuit youth is distinct from industrial and non-industrial counterparts

Journal Article

Commun Biol, 5 (1), 2022.

Abstract | Links:

Nantel S, Bourdin B, Adams K, Carbonneau J, Rabezanahary H, Hamelin MÈ, McCormack D, Savard P, Longtin Y, Cheng MP, De Serres G, Corbeil J, Gilca V, Baz M, Boivin G, Quach C, Decaluwe H

Symptomatology during previous SARS-CoV-2 infection and serostatus before vaccination influence the immunogenicity of BNT162b2 COVID-19 mRNA vaccine

Journal Article

Front Immunol, 13 , 2022.

Abstract | Links:

George PBL, Rossi F, St-Germain MW, Amato P, Badard T, Bergeron MG, Boissinot M, Charette SJ, Coleman BL, Corbeil J, Culley AI, Gaucher ML, Girard M, Godbout S, Kirychuk SP, Marette A, McGeer A, O'Shaughnessy PT, Parmley EJ, Simard S, Reid-Smith RJ, Topp E, Trudel L, Yao M, Brassard P, Delort AM, Larios AD, Létourneau V, Paquet VE, Pedneau MH, Pic É, Thompson B, Veillette M, Thaler M, Scapino I, Lebeuf M, Baghdadi M, Castillo Toro A, Cayouette AB, Dubois MJ, Durocher AF, Girard SB, Diaz AKC, Khalloufi A, Leclerc S, Lemieux J, Maldonado MP, Pilon G, Murphy CP, Notling CA, Ofori-Darko D, Provencher J, Richer-Fortin A, Turgeon N, Duchaine C

Antimicrobial Resistance in the Environment: Towards Elucidating the Roles of Bioaerosols in Transmission and Detection of Antibacterial Resistance Genes

Journal Article

Antibiotics (Basel), 11 (7), 2022.

Abstract | Links:

Maltais-Payette I, Vijay J, Simon MM, Corbeil J, Brière F, Grundberg E, Tchernof A

Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity

Journal Article

Amino Acids, 54 (9), 2022.

Abstract | Links:

Gobeil É, Maltais-Payette I, Taba N, Brière F, Ghodsian N, Abner E, Bourgault J, Gagnon E, Manikpurage HD, Couture C, Mitchell PL, Mathieu P, Julien F, Corbeil J, Vohl MC, Thériault S, Esko T, Tchernof A, Arsenault BJ

Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease

Journal Article

Metabolites, 12 (5), 2022.

Abstract | Links:

Déraspe M, Boisvert S, Laviolette F, Roy PH, Corbeil J

Flexible protein database based on amino acid k-mers

Journal Article

Sci Rep, 12 (1), 2022.

Abstract | Links:

Racine É, Boivin G, Longtin Y, McCormack D, Decaluwe H, Savard P, Cheng MP, Hamelin MÈ, Carbonneau J, Tadount F, Adams K, Bourdin B, Nantel S, Gilca V, Corbeil J, De Serres G, Quach-Thanh C

The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers

Journal Article

Influenza Other Respir Viruses, 16 (5), 2022.

Abstract | Links:

Uyar O, Dominguez JM, Bordeleau M, Lapeyre L, Ibáñez FG, Vallières L, Tremblay ME, Corbeil J, Boivin G

Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response

Journal Article

J Neuroinflammation, 19 (1), 2022.

Abstract | Links:

Hosseini SN, Das PS, Gagnon-Turcotte G, George PBL, Messaddeq Y, Corbeil J, Gosselin B

Optimization & Characterization of Interdigitated Electrodes for Microbial Growth Monitoring

Journal Article

Annu Int Conf IEEE Eng Med Biol Soc, 2021 , 2021.

Abstract | Links:

Abed JY, Déraspe M, Bérubé È, D'Iorio M, Dewar K, Boissinot M, Corbeil J, Bergeron MG, Roy PH

Complete Genome Sequences of Klebsiella michiganensis and Citrobacter farmeri, KPC-2-Producers Serially Isolated from a Single Patient

Journal Article

Antibiotics (Basel), 10 (11), 2021.

Abstract | Links:

153 entries « ‹ 1 of 16 › »
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Active projects

  • Antimicrobial resistance genes in bioaerosols in Canadian arctic, rural, and urban environments: sources, profiles, transport and fate, from 2019-12-01 to 2024-11-30
  • Calcul Québec, from 2015-04-01 to 2023-03-31
  • Chaire de recherche du Canada en Medical genomics, from 2018-01-01 to 2024-12-31
  • Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle, from 2020-04-01 to 2023-03-31
  • Développement d'une technologie de contrôle de la qualité des plantes en cours du procédé manufacturier de médicaments en utilisant la spectrométrie de masse à haut débit couplée à des approches en apprentissage automatique , from 2020-03-19 to 2023-03-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3, from 2019-11-01 to 2024-10-31
  • Ecogenomics of mining areas for sustainable Canadian North (GENOSCAN), from 2020-11-01 to 2024-12-31
  • Extreme zooming on intestinal permeability and the western-style diet: Unravelling the role of dietary antigens on the prevalence of cardiometabolic and mental health diseases in the North, from 2020-11-01 to 2024-12-31
  • L'empreinte métabolomique plasmatique des produits laitiers: un reflet de leur consommation et une fenêtre sur leurs effets cardiométaboliques, from 2022-10-01 to 2024-09-30
  • Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique, from 2018-04-01 to 2024-03-31
  • Prédire l'évolution de l'hépatite C par la fédération de données et l'intelligence artificielle : enjeux éthiques, juridiques, sociaux et de vie privée, from 2019-04-01 to 2024-03-31
  • Unravelling the impact of diet on cardiovascular health in heterozygous familial hypercholesterolemia: a metabolomic approach, from 2021-10-01 to 2025-09-30
  • UVILUQ: l'utilisation des biopsie liquides pour le monitoring de l'état de santé des écosystèmes marins côtiers, from 2020-07-01 to 2023-06-30
  • Validation de la mesure d’expression génique unicellulaire à partir d’un échantillon de tissu hépatique chez des sujets avec une suspicion clinique de stéatose hépatique non-alcoolique., from 2022-08-24 to 2023-08-23
  • Validation des marqueurs cellulaires ChromaLive sur modèles d'organopuces, from 2022-12-12 to 2023-08-23

Recently finished projects

  • Acides biliaires et maladies inflammatoires chroniques de l’intestin : et si la solution était dans l’assiette?, from 2022-03-03 to 2023-03-02
  • Concert pour la vie, from 2020-11-13 to 2021-03-31
  • COVID19 persistent symptomatology: an investigation of the metabolomic and proteomic underpinning, from 2021-06-01 to 2022-05-31
  • Deciphering breast cancer HER2-negativity with regard to HER2-targeted therapy, from 2016-07-01 to 2021-06-30
  • La plateforme bio-environnementale EcoChip: Prototypage d'une preuve de concept robuste, from 2020-03-01 to 2021-06-01
  • MAchine learning for diGItal diagnosTICS of antimicrobial resistance, from 2019-10-01 to 2022-09-30
  • Profil moléculaire sanguin de patientes souffrant de lupus, from 2019-04-01 to 2021-03-31
Data provided by the Université Laval research projects registery