Dr. Iwona Rudkowska is an Assistant professor in the Department of Kinesiology at Laval University, and a researcher at the Endocrinology and Nephrology Unit of CHU de Québec Research Center. She completed her university studies in nutrition at McGill University before pursuing postdoctoral training in nutritional genomics at Laval University. Her unique training as a dietitian and researcher, has led her to become a respected young scientist in nutrigenomics, fatty acids, and metabolic health.

Using genomics for the development of personalized nutrition interventions for the prevention and management of type 2 diabetes

Type 2 diabetes is an important public health issue. Several nutritional approaches have already been put in place for the prevention and management of diabetes; nevertheless, a large interindividual variability was observed in response to these interventions. It is therefore essential to understand the genetic architecture of the disease in order to be able to predict the response of an individual to a nutritional therapy. Using the profiles generated by experimental methods such as genetics, transcriptomics and metabolomics, the primary goal of her research is to identify molecular markers of an individual at risk of developing diabetes. This knowledge will allow the development of nutritional interventions adapted to each individual, and thus more effective in the prevention and the management of diabetes.

CHUL
2705, boulevard Laurier
T4-50
Québec, Québec
Canada G1V 4G2
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Khorraminezhad L, Rudkowska I

Dairy product intake modifies microRNAs expression among individuals with hyperinsulinemia - A post-intervention cross-sectional study

Journal Article

Lifestyle Genom, 2022.

Abstract | Links:

Keathley J, Garneau V, Marcil V, Mutch DM, Robitaille J, Rudkowska I, Sofian GM, Desroches S, Vohl MC

Nutrigenetics, omega-3 and plasma lipids/lipoproteins/apolipoproteins with evidence evaluation using the GRADE approach: a systematic review

Journal Article

BMJ Open, 12 (2), 2022.

Abstract | Links:

Keathley J, Garneau V, Marcil V, Mutch DM, Robitaille J, Rudkowska I, Sofian G, Desroches S, Vohl MC

Clinical Practice Guidelines Using GRADE and AGREE II for the Impact of Genetic Variants on Plasma Lipid/Lipoprotein/Apolipoprotein Responsiveness to Omega-3 Fatty Acids

Journal Article

Front Nutr, 8 , 2021.

Abstract | Links:

Fougère H, Bilodeau JF, Lavoie PM, Mohamed I, Rudkowska I, Pronovost E, Simonyan D, Berthiaume L, Guillot M, Piedboeuf B, Julien P, Marc I

Docosahexaenoic acid-rich algae oil supplementation on breast milk fatty acid profile of mothers who delivered prematurely: a randomized clinical trial

Journal Article

Sci Rep, 11 (1), 2021.

Abstract | Links:

Khorraminezhad L, Bilodeau JF, Greffard K, Larose J, Rudkowska I

Impact of Dairy Intake on Plasma F-IsoProstane Profiles in Overweight Subjects with Hyperinsulinemia: A Randomized Crossover Trial

Journal Article

Nutrients, 13 (6), 2021.

Abstract | Links:

Khorraminezhad L, Rudkowska I

Effect of Yogurt Consumption on Metabolic Syndrome Risk Factors: a Narrative Review

Journal Article

Curr Nutr Rep, 10 (1), 2021.

Abstract | Links:

Rudkowska I

Genomics and Personalized Nutrition

Journal Article

Nutrients, 13 (4), 2021.

Abstract | Links:

Khorraminezhad L, Leclercq M, O'Connor S, Julien P, Weisnagel SJ, Gagnon C, Droit A, Rudkowska I

Dairy product intake modifies gut microbiota composition among hyperinsulinemic individuals

Journal Article

Eur J Nutr, 60 (1), 2021.

Abstract | Links:

Franck M, de Toro-Martin J, Guenard F, Rudkowska I, Lemieux S, Lamarche B, Couture P, Vohl MC

Prevention of Potential Adverse Metabolic Effects of a Supplementation with Omega-3 Fatty Acids Using a Genetic Score Approach

Journal Article

Lifestyle Genom, 13 (1), 2020.

Abstract | Links:

Khorraminezhad L, Leclercq M, Droit A, Bilodeau JF, Rudkowska I

Statistical and Machine-Learning Analyses in Nutritional Genomics Studies

Journal Article

Nutrients, 12 (10), 2020.

Abstract | Links:

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Active projects

  • Dairy bioactive nutrients synergistic effects against inflammation: nutrigenomics and metabolomics approaches., from 2016-04-01 to 2024-03-31
  • Prix Jeune chercheur·euse Jean-Davignon 2022 du Réseau CMDO. Iwona Rudkowska, from 2021-10-01 to 2023-03-31
  • Utilisation de profils génomiques pour le développement d'interventions nutritionnelles personnalisées pour le diabète et les facteurs de risques associés, from 2019-07-01 to 2024-01-15

Recently finished projects

  • Les maladies cardiométaboliques à l'ère de la révolution numérique, from 2020-01-01 to 2020-12-31
  • Plateforme spécialisée en métabolomique pour les biomarqueurs du risque de diabète associé à la diète, from 2018-08-01 to 2021-07-31
Data provided by the Université Laval research projects registery