Dr. Guy Boivin is a professor in the Department of Microbiology-Immunology and Infectious Diseases of the Faculty of Medicine at Laval University. He holds the Canada Research Chair in Emerging Viruses and Antiviral Resistance, as well as a « Foundation » grant from the Canadian Institutes of Health Research (CIHR). He is also co-principal investigator of major grants, such as the FPQIS ($ 12M), for the development of new generation influenza vaccine in the elderly.
Dr. Boivin is the author or co-author of 300 scientific publications and 350 presentations at various international conferences and symposia. He has also contributed to the creation of 9 patents and is co-founder of the company Signia Therapeutics, specializing in the repositioning of drugs to counter viral respiratory infections. He is also the director of an NC3 laboratory that will be operational in 2018, which will expand the various research projects to highly pathogenic respiratory viruses, such as avian influenza viruses (H5N1, H7N9) and other emerging respiratory viruses. (MERS-CoV).
His research program focuses on the diagnosis, pathogenesis, and treatment of viral infections. He studies herpetic and respiratory viruses, including those causing the flu (including avian flu). More recently, he has also been interested in the Zika virus. He uses cell and molecular biology technologies, as well as different animal models to develop rapid diagnostic tests, evaluate new antiviral molecules, elucidate mechanisms of resistance to antiviral agents, and generate new vaccines. He has developed several multicenter studies to assess the clinical and epidemiological impact of emerging respiratory viruses. He collaborates with several fundamental and clinical research groups as well as various pharmaceutical companies. His work will have a significant impact on the diagnosis, treatment, and prevention of frequent and potentially life-threatening viral infections in certain groups of individuals.
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Pre-Omicron seroprevalence, seroconversion, and seroreversion of infection-induced SARS-CoV-2 antibodies among a cohort of children and teenagers in Montreal, Canada
Journal ArticleInt J Infect Dis, 2023, ISSN: 1201-9712.
Influence of letermovir treatment on gut inflammation in people living with HIV on antiretroviral therapy: protocol of the open-label controlled randomised CIAO study
Journal ArticleBMJ Open, 13 (1), 2023.
Reinfection with SARS-CoV-2 in a patient undergoing chemotherapy for lymphoma: Case report
Journal ArticleJ Assoc Med Microbiol Infect Dis Can, 7 (3), 2022.
Evaluation of the performance of multiple immunoassay diagnostic platforms on the National Microbiology Laboratory SARS-CoV-2 National Serology Panel
Journal ArticleJ Assoc Med Microbiol Infect Dis Can, 7 (3), 2022.
Symptomatology during previous SARS-CoV-2 infection and serostatus before vaccination influence the immunogenicity of BNT162b2 COVID-19 mRNA vaccine
Journal ArticleFront Immunol, 13 , 2022.
A Candidate Therapeutic Monoclonal Antibody Inhibits Both HRSV and HMPV Replication in Mice
Journal ArticleBiomedicines, 10 (10), 2022.
Corrigendum: Pandemics throughout history
Journal ArticleFront Microbiol, 13 , 2022.
Generation and Characterization of Drug-Resistant Influenza B Viruses Selected In Vitro with Baloxavir Acid
Journal ArticlePathogens, 11 (9), 2022.
In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance
Journal ArticleAntimicrob Agents Chemother, 66 (7), 2022.
Older Age and Frailty are Associated with Higher Mortality but Lower ICU Admission with COVID-19
Journal ArticleCan Geriatr J, 25 (2), 2022.
Active projects
- A research program on the pathogenesis, treatment and prevention of respiratory and herpes viruses, from 2016-07-01 to 2023-06-30
- Antiviral Resistance and Benefits of Combination Therapy for Influenza Viruses, from 2023-03-01 to 2024-02-29
- Changement de paradigme dans la conduite d'essais cliniques, from 2021-04-01 to 2024-03-31
- Évaluation des interactions entre des virus respiratoires, from 2022-02-01 to 2025-01-31
- Laboratoire international associé (LIA) sur la pathogenèse, le traitement et la prévention des infections virales respiratoires (LIA RespiVIR), from 2021-07-27 to 2026-07-26
- Manufacturing of antigens and adjuvants for development of vaccines (MAAV), from 2021-07-01 to 2023-03-31
- Relationship between COVID-19 and Parkinson’s disease in a mouse model, from 2022-10-01 to 2023-09-30
- SO05 QC07, Sentinel surveillance for confirmed and suspected cases of covid-19/covsars-2 acute respiratory disease, covid-19 vaccine effectiveness and adverse events following sars-cv-2 vaccines: A study of the Serious Outcomes Surveillance, from 2021-04-01 to 2023-03-31
Recently finished projects
- Canadian Immunization Research Network, from 2014-06-01 to 2021-12-31
- COVID-19 household study to assess secondary attack rates and the proportion asymptomatic, including children, from 2020-06-01 to 2021-05-31
- COVIGRO : Impact de la COVID-19 et du vaccin contre SARS-CoV-2 sur le développement placentaire et foetal, from 2021-12-01 to 2022-11-30
- Évaluation de l'efficacité des probiotiques sur les affections post-COVID-19. , from 2021-06-01 to 2022-03-31
- Évaluation du potentiel thérapeutique de la protectine DX et d'analogues contre la COVID-19 , from 2020-06-01 to 2022-03-31
- Hospital-based surveillance of influenza and routine monitoring of seasonal influenza vaccine effectiveness (VE), from 2020-11-01 to 2022-09-30
- How to better manage infectious diseases in ER by triage with molecular mini-panels for the rapid detection of highly transmissible pathogens, from 2018-10-01 to 2022-09-30
- Innovative therapeutic approaches for the 2019-novel coronavirus, from 2021-03-01 to 2022-02-28
- Modulation des réponses immunitaires à la vaccination contre la COVID-19 par une intervention sur le microbiote intestinal : un essai randomisé contrôlé, from 2021-04-01 to 2022-03-31
- Plateforme de laboratoire de niveau de confinement 3 respiratoire, from 2020-03-25 to 2022-03-27
- Projet du Groupe québécois de recherche sur l'infection périnatale à COVID-19 (Banque de données des grossesses COVID-19), from 2020-04-01 to 2022-03-31
- Seeking for innovative approaches in prevention and cure to COVID-19 disease, from 2020-11-01 to 2021-08-30
- Sentinel surveillance, viral shedding, clinical characteristics and outcomes of confirmed and suspected hospitalized cases of COVID-19/SARS-CoV-2 infection in the Canadian Immunization Research Network (CIRN), from 2020-04-01 to 2022-03-31
- Sex as a Biological Variable Supplement - Innovative therapeutic approaches for the 2019-novel coronavirus, from 2020-05-01 to 2021-03-31