Dr. Éric Boilard, Ph.D., is Full Professor in the Department of Infectious Diseases and Immunity at the Faculty of Medicine at Université Laval, and a researcher at the Center de Recherche du CHU de Québec. He is also co-founder and co-director of the ARThrite Research Center (Arthrite-Research-Treatment) at Université Laval, Director of the Cytometry Platform of the Center de Recherche du CHU de Québec, and is a consulting member of the group International Systemic Lupus Collaborating Clinics (SLICC).

He obtained his doctorate in Microbiology and Immunology at Université Laval (2003) and pursued postdoctoral trainings at the Université de Nice-Sophia-Antipolis (2003-2006) and at Harvard University at the Brigham and Women’s Hospital (2006-2010). It was during his studies at Harvard that Dr. Boilard shed light on the role of platelets in rheumatoid arthritis (Boilard et al. Science 2010).

His work aims to better understand the pathogenesis of autoimmune diseases, notably rheumatic diseases, and to improve the development of new therapies through the development of biomarkers. He examines how platelets and the cells that produce them, called megakaryocytes, contribute to the inflammatory responses in place in rheumatoid arthritis, lupus, and cases of overwhelming inflammatory responses during microbial infections. For his work, he is also considering the extracellular vesicles produced by these cells using advanced technologies. He carries out his research in the clinic through the precious involvement of patients and with the help of mouse models of disease.

He is a renowned scientist and international lecturer recognized by his peers. He has won the Radio-Canada prize for the greatest medical discovery of the year on several occasions and the Radio-Canada and Le Soleil prize for scientist of the year. He is the recipient of the André Dupont prize awarded to the most prolific young Quebec researcher in clinical research and the Cozzarelli Prize awarded by the National Academy of Sciences (United States) in recognition of the excellence and originality of his work.

CHUL
2705, boulevard Laurier
T1-49
Québec, Québec
Canada G1V 4G2
+1 418-525-4444, extension 46175
+1 418-654-2765
Eric.Boilard@crchudequebe...

Latest news

127 entries « ‹ 2 of 13 › »

Boilard E, Bellio M

Platelet extracellular vesicles and the secretory interactome join forces in health and disease

Journal Article

Immunol Rev, 312 (1), 2022.

Abstract | Links:

Dubuc I, Prunier J, Lacasse É, Gravel A, Puhm F, Allaeys I, Archambault AS, Gudimard L, Villano R, Droit A, Flamand N, Boilard É, Flamand L

Cytokines and Lipid Mediators of Inflammation in Lungs of SARS-CoV-2 Infected Mice

Journal Article

Front Immunol, 13 , 2022.

Abstract | Links:

Puhm F, Boilard E

Megakaryocytes and platelets embrace diversity in face of adversity

Journal Article

J Thromb Haemost, 20 (9), 2022.

| Links:

Laroche A, Soulet D, Bazin M, Levesque T, Allaeys I, Vallières N, Gunzer M, Flamand L, Lacroix S, Boilard E

Live imaging of platelets and neutrophils during antibody-mediated neurovascular thrombosis

Journal Article

Blood Adv, 6 (12), 2022.

Abstract | Links:

Puhm F, Allaeys I, Lacasse E, Dubuc I, Galipeau Y, Zaid Y, Khalki L, Belleannée C, Durocher Y, Brisson AR, Wolberg AS, Langlois MA, Flamand L, Boilard E

Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells

Journal Article

Blood Adv, 6 (12), 2022.

Abstract | Links:

Hasse S, Julien AS, Duchez AC, Zhao C, Boilard E, Fortin PR, Bourgoin SG

Red blood cell-derived phosphatidylserine positive extracellular vesicles are associated with past thrombotic events in patients with systemic erythematous lupus

Journal Article

Lupus Sci Med, 9 (1), 2022.

Abstract | Links:

Beillevaire D, Migneault F, Turgeon J, Gingras D, Rimbaud AK, Marcoux G, Spino C, Thibodeau N, Bonneil E, Thibault P, Boilard É, Dieudé M, Hébert MJ

Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes

Journal Article

Cell Death Dis, 13 (2), 2022.

Abstract | Links:

Becker YLC, Gagné JP, Julien AS, Lévesque T, Allaeys I, Gougeard N, Rubio V, Boisvert FM, Jean D, Wagner E, Poirier GG, Fortin PR, Boilard É

Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus

Journal Article

Arthritis Rheumatol, 74 (7), 2022.

Abstract | Links:

Miki Y, Taketomi Y, Kidoguchi Y, Yamamoto K, Muramatsu K, Nishito Y, Park J, Hosomi K, Mizuguchi K, Kunisawa J, Soga T, Boilard E, B Gowda SG, Ikeda K, Arita M, Murakami M

Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota

Journal Article

JCI Insight, 7 (2), 2022.

Abstract | Links:

Doré E, Joly-Beauparlant C, Morozumi S, Mathieu A, Lévesque T, Allaeys I, Duchez AC, Cloutier N, Leclercq M, Bodein A, Payré C, Martin C, Petit-Paitel A, Gelb MH, Rangachari M, Murakami M, Davidovic L, Flamand N, Arita M, Lambeau G, Droit A, Boilard E

The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation

Journal Article

JCI Insight, 7 (2), 2022.

Abstract | Links:

127 entries « ‹ 2 of 13 › »
Signaler des ajouts ou des modifications

Active projects

  • Contribution of phospholipase A2 enzymes in the homeostasis of the immune system., from 2016-04-01 to 2024-03-31
  • COVID-19 trilogy: ARDS, inflammation and coagulopathy, from 2020-06-01 to 2024-03-31
  • Elucidating the role of the pro-inflammatory P2Y14 receptor in acute kidney injury, from 2022-04-01 to 2027-03-31
  • Megakaryocyte: a new player in systemic lupus erythematosus, from 2022-09-01 to 2023-08-31
  • Pathogenic roles of platelets in sepsis, from 2020-03-01 to 2025-03-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-04-01 to 2025-03-31
  • Premier biomarqueur sanguin de la maladie de Parkinson : de la validation à la commercialisation, from 2022-09-14 to 2024-09-13
  • Rôle des microparticules issues du bourgeonnement cellulaire dans les comoribidités associées à l'infection par le VIH, from 2022-02-01 to 2024-01-31
  • Rôle des plaquettes et de leurs microparticules dans l'inflammation, from 2019-08-01 to 2023-07-31
  • Rôle des plaquettes et des vésicules extracellulaires dans l'inflammation, from 2022-01-01 to 2023-05-31
  • Role of megakaryocytes in Systemic Lupus Erythematosus, from 2023-04-01 to 2028-03-31

Recently finished projects

  • Computer-Aided Sperm Analysis (CASA) of sperm motility and hyperactivation, from 2021-04-01 to 2022-03-31
  • Mapping anti-mitochondrial antibodies in systemic lupus erythematosus, from 2019-04-01 to 2022-03-31
  • Pathogenesis and immune escape potential of SARS-CoV-2 variants of concern, from 2021-06-01 to 2022-05-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-01-01 to 2022-12-31
  • Role of antibodies in platelet response to SARS-CoV-2 and its variants, from 2021-06-01 to 2022-05-31
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., from 2015-07-01 to 2023-03-31
  • Role of platelets and their mother cell, the megakaryocyte, in COVID-19, from 2021-03-01 to 2022-02-28
  • The Canadian National Transplant Research Program : Increasing Donation and Improving Transplantation Outcomes, from 2013-04-01 to 2022-03-31
  • The impact of antimalarial drugs in arthritis patients exposed to SARS-CoV-2- the CoVIRAL project, from 2020-04-01 to 2023-03-31
  • Understanding the pathogenesis of COVID-19, from 2020-03-01 to 2023-02-28
Data provided by the Université Laval research projects registery