Dr. Gagnon is an adult endocrinologist. She has completed a 3-year research fellowship in metabolic bone diseases and phosphocalcic metabolism disorders. She is a clinician researcher at the CHU de Québec-Laval University Research Centre and a Professor at Laval University’s School of Medicine. She is also an associate researcher at Laval University’s Institute of Nutrition and Functional Foods. Her research focusses on the impact of obesity and type 2 diabetes treatments on bone health (including bariatric surgery and medical treatments). She also works on the effects of vitamin D and other nutrients on the prevention of type 2 diabetes and, finally, on phosphocalcic metabolism disorders. Her research is financed by Diabète Québec, Diabetes Canada, and the Canadian Institutes of Health Research.

Dr. Gagnon has received several prizes and honours, including the 2017 research prize from the Fédération des médecins spécialistes du Québec, a 2015 young investigator award from the American Society for Bone and Mineral Research, an award at the 2015 International Symposium on the Nutritional Aspects of Osteoporosis, and a 2019 Jean-Davignon young investigator award from the FRQ-S cardiometabolic, diabetes and obesity network.

To evaluate the impact of bariatric surgery and other obesity treatments on bone health

Bariatric surgery is associated with clear benefits on reducing obesity-related diseases. However, data cumulated over the last few years suggest that certain types of bariatric procedures have adverse effects on bone health. Moreover, the effect of medical weight loss on bone health is not well studied. Dr. Gagnon’s research aims at evaluating the impact of different types of bariatric procedures and obesity treatments on bone markers, and to determine the mechanisms by which they influence bone health.

To evaluate the effects of vitamin D and other nutrients on the risk of developing type 2 diabetes

Certain nutrients hold promise to decrease the risk of diabetes in people at high risk. Dr. Gagnon’s expertise is to perform clinical trials to evaluate whether these nutrients are effective.

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Québec, Québec
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78 entries « 1 of 8 »

Morissette A, Agrinier AL, Gignac T, Ramadan L, Diop K, Marois J, Varin TV, Pilon G, Simard S, Larose É, Gagnon C, Arsenault BJ, Després JP, Carreau AM, Vohl MC, Marette EA, Marette A

Substituting Refined Sugars With Maple Syrup Decreases Key Cardiometabolic Risk Factors in Individuals With Mild Metabolic Alterations: A Randomized, Double-Blind, Controlled Crossover Trial

Journal Article

J Nutr, 154 (10), 2024.

Abstract | Links:

Clarke BL, Khan AA, Rubin MR, Schwarz P, Vokes T, Shoback DM, Gagnon C, Palermo A, Abbott LG, Hofbauer LC, Kohlmeier L, Cetani F, Pihl S, An X, Smith AR, Lai B, Ukena J, Sibley CT, Shu AD, Rejnmark L

Efficacy and Safety of TransCon PTH in Adults with Hypoparathyroidism: 52-Week Results From the Phase 3 PaTHway Trial

Journal Article

J Clin Endocrinol Metab, 2024.

Abstract | Links:

Allaire J, Lévesque B, Poirier P, Gagnon C, Auclair G, Lemire M, Ayotte P

Prevalence and determinants of hypertension in the adult Inuit population of Nunavik (northern Quebec, Canada)

Journal Article

Can J Public Health, 115 (Suppl 1), 2024.

Abstract | Links:

Gignac T, Trépanier G, Pradeau M, Morissette A, Agrinier AL, Larose É, Marois J, Pilon G, Gagnon C, Vohl MC, Marette A, Carreau AM

Metabolic-associated fatty liver disease is characterized by a post-oral glucose load hyperinsulinemia in individuals with mild metabolic alterations

Journal Article

Am J Physiol Endocrinol Metab, 326 (5), 2024.

Abstract | Links:

Coll JC, Turcotte AF, Leslie WD, Michou L, Weisnagel SJ, Mac-Way F, Albert C, Berger C, Morin SN, Rabasa-Lhoret R, Gagnon C

Advanced glycation end products are not associated with bone mineral density, trabecular bone score, and bone turnover markers in adults with and without type 1 diabetes: a cross-sectional study

Journal Article

JBMR Plus, 8 (3), 2024.

Abstract | Links:

Giustina A, di Filippo L, Facciorusso A, Adler RA, Binkley N, Bollerslev J, Bouillon R, Casanueva FF, Cavestro GM, Chakhtoura M, Conte C, Donini LM, Ebeling PR, Fassio A, Frara S, Gagnon C, Latella G, Marcocci C, Mechanick JI, Minisola S, Rizzoli R, Santini F, Shaker JL, Sempos C, Ulivieri FM, Virtanen JK, Napoli N, Schafer AL, Bilezikian JP

Correction: Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta‑analysis

Journal Article

Rev Endocr Metab Disord, 25 (2), 2024.

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Rejnmark L, Gosmanova EO, Khan AA, Makita N, Imanishi Y, Takeuchi Y, Sprague S, Shoback DM, Kohlmeier L, Rubin MR, Palermo A, Schwarz P, Gagnon C, Tsourdi E, Zhao C, Makara MA, Ominsky MS, Lai B, Ukena J, Sibley CT, Shu AD

Palopegteriparatide Treatment Improves Renal Function in Adults with Chronic Hypoparathyroidism: 1-Year Results from the Phase 3 PaTHway Trial

Journal Article

Adv Ther, 41 (6), 2024.

Abstract | Links:

Hundemer GL, Agharazii M, Madore F, Piché ME, Gagnon C, Bussières A, St-Jean M, Leung AA, Kline GA, Sood MM, Burger D, Ramsay T, Goupil R

Sex-Specific Associations of Aldosterone and Renin with Body Composition: A Population-Based Cohort Study

Journal Article

J Clin Endocrinol Metab, 2024.

Abstract | Links:

Khan AA, Abbott LG, Ahmed I, Ayodele O, Gagnon C, Finkelman RD, Mezosi E, Rejnmark L, Takacs I, Yin S, Ing SW

Open-label extension of a randomized trial investigating safety and efficacy of rhPTH(1-84) in hypoparathyroidism

Journal Article

JBMR Plus, 8 (3), 2024.

Abstract | Links:

Mitchell PL, Pilon G, Bazinet L, Gagnon C, Weisnagel SJ, Jacques H, Vohl MC, Marette A

Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients-it takes a village

Journal Article

Appl Physiol Nutr Metab, 49 (11), 2024.

Abstract | Links:

78 entries « 1 of 8 »
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Active projects

  • A new focus on protein and the gut microbiota to explain health benefits of dairy foods, from 2022-01-01 to 2024-12-31
  • Bone and Muscle Health Following Sleeve Gastrectomy in Men, Premenopausal and Postmenopausal Women, from 2022-04-01 to 2027-03-31
  • Chaire de recherche diabète et maladies endocriniennes, from 2023-04-27 to 2025-04-26
  • Covid-19 effects on ARTErial StIffness and vascular AgiNg (CARTESIAN) study- Canada, from 2021-06-01 to 2025-03-31
  • Effet de contrôle glycémique sur la progression de la stéatose hépatique au sein du REGISTRE-NASH du CHU de Québec-Université Laval, from 2024-01-23 to 2024-12-31
  • Identifying low bone turnover disease in chronic kidney disease in order to guide anti-fracture therapy, from 2020-10-01 to 2025-09-30
  • Impact de l'obésité, du diabète et de la chirurgie bariatrique sur la santé osseuse., from 2023-07-01 to 2025-06-30
  • Impact of glycemic control on skeletal outcomes in adults with type 1 diabetes, from 2022-12-01 to 2025-11-30
  • Impact of Glycemic Variability on Cognitive Impairment, Disordered Eating Behaviors and Self-Management Skills in Patients with Type 1 Diabetes, from 2021-12-01 to 2025-11-30
  • La santé osseuse après une chirurgie bariatrique chez des patients ayant un diabète de type 2 - suivi 3 ans post chirurgie, from 2022-01-01 to 2024-12-31
  • Multifaceted Intervention using Telehealth to Reduce the risk of Falls and Fractures in Older Men (MisterFit study): a Pilot Study , from 2021-10-01 to 2025-09-30
  • Santé osseuse et musculaire après une gastrectomie en manchon chez des hommes, des femmes préménopausées et des femmes ménopausées, from 2023-03-01 to 2028-07-01

Recently finished projects

  • Bone health after bariatric surgery in patient with type 2 diabetes, from 2017-07-01 to 2022-12-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3, from 2019-11-01 to 2024-10-31
  • Institut sur la nutrition et les aliments fonctionnels (INAF), from 2017-04-01 to 2024-03-31
  • Prix Jeune Chercheur 2022 de la Société canadienne d'endocrinologie et métabolisme, from 2022-09-14 to 2024-09-13
  • Traiter l’os pour prévenir l’hypertension et les maladies cardiovasculaires chez les femmes ménopausées., from 2021-05-01 to 2023-06-30
  • Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients: from animal models to obese insulin-resistant subjects, from 2013-06-01 to 2023-03-31
Data provided by the Université Laval research projects registery