Caroline Sirois is a professor in the Department of Social and Preventive Medicine at Laval University. She is a researcher at the CHU de Québec Research Center, the Center of Excellence on Aging in Quebec, the Center for Research in Primary Care and Services at Laval University, and a research associate at the Institut national de santé publique du Québec (INSPQ). Since July 2016, she holds the Chair of Research on Aging at Laval University. As a pharmacist with a master’s degree in hospital pharmacy, Ms. Sirois practiced in community pharmacies and hospital settings before completing a master’s degree and a doctorate in pharmacoepidemiology at Laval University. She then completed postdoctoral training in epidemiology at McGill University.

Her research interests focus on the appropriate use of drugs in older adults, polypharmacy, and deprescribing. Her interests include the study of potentially inappropriate drugs for older individuals and the conceptualization of appropriate polypharmacy. By using multicriteria analysis methods, she tries to determine which drug combinations generate more benefits than adverse effects on the health and quality of life of patients. She is also interested in deprescribing, both from the perspective of older adults, and clinicians.

Ms. Sirois works closely with the INSPQ on the development of polypharmacy surveillance for people aged 65 and over in Quebec. This project involves the development of polypharmacy indicators on which she collaborates with several international teams.

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Maltais A, Simard M, Vedel I, Sirois C

Changes in Polypharmacy and Psychotropic Medication Use After Diagnosis of Major Neurocognitive Disorders: A Population-based Study in Québec, Canada

Journal Article

Alzheimer Dis Assoc Disord, 2022.

Abstract | Links:

Fortin E, Quach C, Dionne M, Irace-Cima A, Sirois C, Simard M, Jean S, Ufitinema NM

Impact des maladies chroniques sur les taux d’utilisation des antibiotiques dans la communauté

Book

Institut national de santé publique du Québec, Québec, QC, 2022, ISBN: 9782550914860.

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Côté C, Bérubé M, Moore L, Lauzier F, Tremblay L, Belzile E, Martel MO, Pagé G, Beaulieu Y, Pinard AM, Perreault K, Sirois C, Grzelak S, Turgeon AF

Strategies aimed at preventing long-term opioid use in trauma and orthopaedic surgery: a scoping review

Journal Article

BMC Musculoskelet Disord, 23 (1), 2022.

Abstract | Links:

Guénette L, Turcotte V, Bélanger L, Blais L, Sirois C, Lunghi C, Duncan P

Multimorbidity Treatment Burden Questionnaire (MTBQ): Translation, Cultural Adaptation, and Validation in French-Canadian

Journal Article

Can J Aging, 2022.

Abstract | Links:

Sirois C, Boiteau V, Chiu Y, Gilca R, Simard M

Exploring the associations between polypharmacy and COVID-19-related hospitalisations and deaths: a population-based cohort study among older adults in Quebec, Canada

Journal Article

BMJ Open, 12 (3), 2022.

Abstract | Links:

Rakheja B, Sirois C, Ouellet N, Roux B, Laroche ML

Attitudes Toward Deprescribing in Older Adults and Caregivers: A Survey in Quebec, Canada

Journal Article

J Appl Gerontol, 41 (5), 2022.

Abstract | Links:

Cossette B, Ricard G, Poirier R, Gosselin S, Langlois MF, Imbeault P, Breton M, Couturier Y, Sirois C, Lessard-Beaudoin M, Rodrigue C, Teasdale J, Turcotte JP, Mallet L

Pharmacist-led transitions of care between hospitals, primary care clinics, and community pharmacies

Journal Article

J Am Geriatr Soc, 70 (3), 2022.

Abstract | Links:

Gosselin E, Simard M, Lunghi C, Sirois C

Trends in benzodiazepine and alternative hypnotic use in relation with multimorbidity among older adults in Quebec, Canada

Journal Article

Pharmacoepidemiol Drug Saf, 31 (3), 2022.

Abstract | Links:

Simard M, Rahme E, Calfat AC, Sirois C

Multimorbidity measures from health administrative data using ICD system codes: A systematic review

Journal Article

Pharmacoepidemiol Drug Saf, 31 (1), 2022.

Abstract | Links:

Ouali A, Simard M, Sirois C,

Portrait de la polypharmacie chez les aînés québécois atteints de maladie pulmonaire obstructive chronique entre 2000 et 2015

Book

Institut national de santé publique, Montréal, QC, 2021.

Abstract | Links:

83 entries « 1 of 9 »
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Active projects

  • Co-construction d'un Living lab au sein des maisons des aînés et alternatives, from 2022-05-01 to 2023-04-30
  • Démarrage d'un nouveau professeur, from 2020-01-01 to 2023-12-31
  • Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle, from 2020-04-01 to 2023-03-31
  • Impacts de la pandémie sur la consommation de médicaments et la polypharmacie par le régime public d’assurance médicaments du Québec dans la population assurée, from 2022-03-16 to 2023-03-31
  • Maisons des aînés et maisons alternatives : étude observationnelle de la transition et de l'intégration des nouveaux résidents dans ce nouvel hébergement, from 2022-03-16 to 2023-03-31
  • Pharmacie sans médicaments: exploration des impacts des services cliniques offerts aux aînés québécois polymédicamentés, from 2021-02-19 to 2023-03-31
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, from 2019-04-01 to 2024-03-31
  • Polymédication et usage approprié des médicaments chez les aînés québécois, from 2021-07-01 to 2024-06-30
  • Primary care reform and medication appropriateness for seniors: A comparative study of two provinces, from 2018-04-01 to 2023-03-31
  • Projet GPS: Évaluation de l'impact de la réorganisation du travail en Groupe de médecine de famille (GMF) sur la Pharmacothérapie et le Soutien à l'autonomie des personnes âgées ayant un trouble neuro-cognitif majeur, from 2019-04-01 to 2022-06-30
  • Real-World Evaluation of the Efficacy, Safety and Cost-Effectiveness of Statins for Primary Prevention of Cardiovascular Disease Among the Elderly – A Causal Perspective to Treatment Trajectory Analysis, from 2019-10-01 to 2023-03-31
  • Suivi de la qualité de la pratique de l'électroconvulsivothérapie au Québec basé sur le recueil de données médico-administratives, cliniques et socio-démographiques en contexte réel, from 2020-01-01 to 2022-11-30

Recently finished projects

  • Chaire de recherche sur le vieillissement, from 2016-07-01 to 2021-12-14
  • Étude de la polymédication chez les aînés québécois, from 2016-07-01 to 2020-06-30
  • Fonds de soutien du CERSSPL-UL pour chercheure-boursière, from 2016-11-18 to 2020-11-17
  • La polypharmacie est-elle un risque pour la santé des aînés?, from 2020-03-17 to 2022-03-31
  • Maison des aînés : étude d'un modèle d'habitation innovant dans une perspective de relance de l'économie et de progrès de notre société suite à la pandémie de COVID-19., from 2021-04-01 to 2022-05-31
  • Portrait de la polypharmarcie et de la qualité des traitements des personnes âgées atteintes de schizophrénie au Québec: étude populationnelle de 2000 à 2018, from 2020-04-01 to 2021-03-31
  • Predicting population risk of suicide using health administrative data, from 2020-03-31 to 2022-03-30
  • The Multimorbidity Treatment Burden Questionnaire (MTBQ): translation and validation in French, from 2019-04-01 to 2020-09-30
Data provided by the Université Laval research projects registery