Caroline Sirois is a professor in the Department of Social and Preventive Medicine at Laval University. She is a researcher at the CHU de Québec Research Center, the Center of Excellence on Aging in Quebec, the Center for Research in Primary Care and Services at Laval University, and a research associate at the Institut national de santé publique du Québec (INSPQ). Since July 2016, she holds the Chair of Research on Aging at Laval University. As a pharmacist with a master’s degree in hospital pharmacy, Ms. Sirois practiced in community pharmacies and hospital settings before completing a master’s degree and a doctorate in pharmacoepidemiology at Laval University. She then completed postdoctoral training in epidemiology at McGill University.

Her research interests focus on the appropriate use of drugs in older adults, polypharmacy, and deprescribing. Her interests include the study of potentially inappropriate drugs for older individuals and the conceptualization of appropriate polypharmacy. By using multicriteria analysis methods, she tries to determine which drug combinations generate more benefits than adverse effects on the health and quality of life of patients. She is also interested in deprescribing, both from the perspective of older adults, and clinicians.

Ms. Sirois works closely with the INSPQ on the development of polypharmacy surveillance for people aged 65 and over in Quebec. This project involves the development of polypharmacy indicators on which she collaborates with several international teams.

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+1 418-525-4444, extension 84712+1 418-656-2131, extension 412340
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Latest news

  • Campeau Calfat, AlexandreDoctoral student

  • Gagnon, Marie-ÈveDoctoral student
    Hôpital Saint-Sacrement
    1050 Chemin Sainte-Foy
    Québec, QC
    Canada G1S 4L8
  • Guay, Charles-AntoineDoctoral student

  • Missaoui, HoussemMaster student

  • Simard, MarcDoctoral student

103 entries « ‹ 1 of 11 › »

Mésidor M, Talbot D, Simard M, Blais C, Boiteau V, Sirois C

Sex-specific medication trajectories in older adults newly diagnosed with diabetes

Journal Article

Explor Res Clin Soc Pharm, 11 , 2023.

Abstract | Links:

Sirois C, Gosselin M, Laforce C, Gagnon ME, Talbot D

How does deprescribing (not) reduce mortality? A review of a meta-analysis in community-dwelling older adults casts uncertainty over claimed benefits

Journal Article

Basic Clin Pharmacol Toxicol, 2023.

Abstract | Links:

Mésidor M, Sirois C, Simard M, Talbot D

A bootstrap approach for evaluating uncertainty in the number of groups identified by latent class growth models

Journal Article

Am J Epidemiol, 2023.

Abstract | Links:

Farrell B, Raman-Wilms L, Sadowski CA, Mallery L, Turner J, Gagnon C, Cole M, Grill A, Isenor JE, Mangin D, McCarthy LM, Schuster B, Sirois C, Sun W, Upshur R

A Proposed Curricular Framework for an Interprofessional Approach to Deprescribing

Journal Article

Med Sci Educ, 33 (2), 2023.

Abstract | Links:

Lunghi C, Rochette L, Massamba V, Tardif I, Ouali A, Sirois C

Psychiatric and non-psychiatric polypharmacy among older adults with schizophrenia: Trends from a population-based study between 2000 and 2016

Journal Article

Front Pharmacol, 14 , 2023.

Abstract | Links:

Ly A, Sirois C, Dionne CE

Sensitivity and specificity of algorithms for the identification of nonspecific low back pain in medico-administrative databases

Journal Article

Pain, 164 (7), 2023.

Abstract | Links:

Austin N, Rudoler D, Allin S, Dolovich L, Glazier RH, Grudniewicz A, Martin E, Sirois C, Strumpf E

Team-based primary care reforms and older adults: a descriptive assessment of sociodemographic trends and prescribing endpoints in two Canadian provinces

Journal Article

BMC Prim Care, 24 (1), 2023.

Abstract | Links:

Lafrenière S, Gholi-Zadeh-Kharrat F, Sirois C, Massamba V, Rochette L, Brousseau-Paradis C, Patry S, Gagné C, Lemasson M, Gariépy G, Mérette C, Rahme E, Lesage A

The 5-year longitudinal diagnostic profile and health services utilization of patients treated with electroconvulsive therapy in Quebec: a population-based study

Journal Article

Soc Psychiatry Psychiatr Epidemiol, 58 (4), 2023.

Abstract | Links:

Talbot D, Mésidor M, Chiu Y, Simard M, Sirois C

An Alternative Perspective on the Robust Poisson Method for Estimating Risk or Prevalence Ratios

Journal Article

Epidemiology, 34 (1), 2023.

Abstract | Links:

Guénette L, Turcotte V, Bélanger L, Blais L, Sirois C, Lunghi C, Duncan P

Multimorbidity Treatment Burden Questionnaire (MTBQ): Translation, Cultural Adaptation, and Validation in French-Canadian

Journal Article

Can J Aging, 42 (1), 2023.

Abstract | Links:

103 entries « ‹ 1 of 11 › »
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Active projects

  • Association entre les taux d’utilisation des antibiotiques et la fréquence des gènes de résistance aux antibiotiques dans les eaux usées de la région de Laval pendant la pandémie COVID-19, from 2023-02-08 to 2024-03-31
  • Démarrage d'un nouveau professeur, from 2020-01-01 to 2023-12-31
  • Impacts de la pandémie sur la consommation de médicaments et la polypharmacie par le régime public d’assurance médicaments du Québec dans la population assurée, from 2022-03-16 to 2024-03-31
  • Pharmacie sans médicaments: exploration des impacts des services cliniques offerts aux aînés québécois polymédicamentés, from 2021-02-19 to 2024-03-31
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, from 2019-04-01 to 2024-03-31
  • Polymédication et usage approprié des médicaments chez les aînés québécois, from 2021-07-01 to 2024-06-30
  • Primary care reform and medication appropriateness for seniors: A comparative study of two provinces, from 2018-04-01 to 2024-03-31
  • Projet GPS: Évaluation de l'impact de la réorganisation du travail en Groupe de médecine de famille (GMF) sur la Pharmacothérapie et le Soutien à l'autonomie des personnes âgées ayant un trouble neuro-cognitif majeur, from 2019-04-01 to 2024-03-31
  • Suivi de la qualité de la pratique de l'électroconvulsivothérapie au Québec basé sur le recueil de données médico-administratives, cliniques et socio-démographiques en contexte réel, from 2020-01-01 to 2023-09-30

Recently finished projects

  • Chaire de recherche sur le vieillissement, from 2016-07-01 to 2021-12-14
  • Co-construction d'un Living lab au sein des maisons des aînés et alternatives, from 2022-05-01 to 2023-04-30
  • Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle, from 2020-04-01 to 2023-03-31
  • La polypharmacie est-elle un risque pour la santé des aînés?, from 2020-03-17 to 2022-03-31
  • Maison des aînés : étude d'un modèle d'habitation innovant dans une perspective de relance de l'économie et de progrès de notre société suite à la pandémie de COVID-19., from 2021-04-01 to 2022-05-31
  • Maisons des aînés et maisons alternatives : étude observationnelle de la transition et de l'intégration des nouveaux résidents dans ce nouvel hébergement, from 2022-03-16 to 2023-03-31
  • Optimisation 2.0 de la prise en charge en phase aiguë des fractures de la hanche chez l’aîné , from 2022-04-01 to 2023-03-31
  • Predicting population risk of suicide using health administrative data, from 2020-03-31 to 2022-03-30
  • Real-World Evaluation of the Efficacy, Safety and Cost-Effectiveness of Statins for Primary Prevention of Cardiovascular Disease Among the Elderly – A Causal Perspective to Treatment Trajectory Analysis, from 2019-10-01 to 2023-03-31
Data provided by the Université Laval research projects registery