Caroline Sirois is a professor in the Department of Social and Preventive Medicine at Laval University. She is a researcher at the CHU de Québec Research Center, the Center of Excellence on Aging in Quebec, the Center for Research in Primary Care and Services at Laval University, and a research associate at the Institut national de santé publique du Québec (INSPQ). Since July 2016, she holds the Chair of Research on Aging at Laval University. As a pharmacist with a master’s degree in hospital pharmacy, Ms. Sirois practiced in community pharmacies and hospital settings before completing a master’s degree and a doctorate in pharmacoepidemiology at Laval University. She then completed postdoctoral training in epidemiology at McGill University.

Her research interests focus on the appropriate use of drugs in older adults, polypharmacy, and deprescribing. Her interests include the study of potentially inappropriate drugs for older individuals and the conceptualization of appropriate polypharmacy. By using multicriteria analysis methods, she tries to determine which drug combinations generate more benefits than adverse effects on the health and quality of life of patients. She is also interested in deprescribing, both from the perspective of older adults, and clinicians.

Ms. Sirois works closely with the INSPQ on the development of polypharmacy surveillance for people aged 65 and over in Quebec. This project involves the development of polypharmacy indicators on which she collaborates with several international teams.

1050, Avenue de la médecine
L2-28
Québec, Qc
Canada G1S 4L8
+1 418-525-4444, extension 84712+1 418-656-2131, extension 412340
caroline.sirois@crchudequ... Caroline.Sirois@pha.ulava...

Latest news

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Lunghi C, Rochette L, Massamba V, Tardif I, Ouali A, Sirois C

Psychiatric and non-psychiatric polypharmacy among older adults with schizophrenia: Trends from a population-based study between 2000 and 2016

Journal Article

Front Pharmacol, 14 , 2023.

Abstract | Links:

Ly A, Sirois C, Dionne CE

Sensitivity and specificity of algorithms for the identification of nonspecific low back pain in medico-administrative databases

Journal Article

Pain, 2023.

Abstract | Links:

Austin N, Rudoler D, Allin S, Dolovich L, Glazier RH, Grudniewicz A, Martin E, Sirois C, Strumpf E

Team-based primary care reforms and older adults: a descriptive assessment of sociodemographic trends and prescribing endpoints in two Canadian provinces

Journal Article

BMC Prim Care, 24 (1), 2023.

Abstract | Links:

Talbot D, Mésidor M, Chiu Y, Simard M, Sirois C

An Alternative Perspective on the Robust Poisson Method for Estimating Risk or Prevalence Ratios

Journal Article

Epidemiology, 34 (1), 2023.

Abstract | Links:

Guénette L, Turcotte V, Bélanger L, Blais L, Sirois C, Lunghi C, Duncan P

Multimorbidity Treatment Burden Questionnaire (MTBQ): Translation, Cultural Adaptation, and Validation in French-Canadian

Journal Article

Can J Aging, 42 (1), 2023.

Abstract | Links:

Bédard E, Ouellet N, Cormier C, Dugas M, Sirois C, Sylvain H

[Portrait of the Women's Mental Health who Consult Community Organization of a Quebec Region]

Journal Article

Sante Ment Que, 47 (1), 2022.

Abstract | Links:

Ouellet N, Bergeron AS, Gagnon E, Cossette B, Labrecque CA, Sirois C

Prescribing and deprescribing in very old age: perceptions of very old adults, caregivers and health professionals

Journal Article

Age Ageing, 51 (11), 2022.

Abstract | Links:

Guénette L, Kröger E, Bonnan D, Maheu A, Morin M, Bélanger L, Vedel I, Wilchesky M, Sirois C, Durand E, Couturier Y, Sourial N, Dallaire C

Reorganizing Pharmaceutical Care in Family Medicine Groups for Older Adults With or at Risk of Major Neurocognitive Disorders: Protocol for a Mixed Methods Study

Journal Article

JMIR Res Protoc, 11 (11), 2022.

Abstract | Links:

Beck A, Persaud N, Tessier LA, Grad R, Kidd MR, Klarenbach S, Korownyk C, Moore A, Thombs BD, Mangin D, McCracken RK, McDonald EG, Sirois C, Kanji S, Molnar F, Nicholls SG, Thavorn K, Bennett A, Shaver N, Skidmore B, Mitchelmore BR, Avey M, Rolland-Harris E, Little J, Moher D

Interventions to address potentially inappropriate prescriptions and over-the-counter medication use among adults 65 years and older in primary care settings: protocol for a systematic review

Journal Article

Syst Rev, 11 (1), 2022.

Abstract | Links:

Duval C, Sirois C, Savoie-White FH, Tardif PA, Bérubé M, Turgeon AF, Cook DJ, Lauzier F, Moore L

Effect of Intermittent Pneumatic Compression in Addition to Pharmacologic Prophylaxis for Thromboprophylaxis in Hospitalized Adult Patients: A Systematic Review and Meta-Analysis

Journal Article

Crit Care Explor, 4 (10), 2022.

Abstract | Links:

99 entries « ‹ 1 of 10 › »
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Active projects

  • Association entre les taux d’utilisation des antibiotiques et la fréquence des gènes de résistance aux antibiotiques dans les eaux usées de la région de Laval pendant la pandémie COVID-19, from 2023-02-08 to 2024-03-31
  • Co-construction d'un Living lab au sein des maisons des aînés et alternatives, from 2022-05-01 to 2023-04-30
  • Démarrage d'un nouveau professeur, from 2020-01-01 to 2023-12-31
  • Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle, from 2020-04-01 to 2023-03-31
  • Impacts de la pandémie sur la consommation de médicaments et la polypharmacie par le régime public d’assurance médicaments du Québec dans la population assurée, from 2022-03-16 to 2023-03-31
  • Maisons des aînés et maisons alternatives : étude observationnelle de la transition et de l'intégration des nouveaux résidents dans ce nouvel hébergement, from 2022-03-16 to 2023-03-31
  • Pharmacie sans médicaments: exploration des impacts des services cliniques offerts aux aînés québécois polymédicamentés, from 2021-02-19 to 2023-03-31
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, from 2019-04-01 to 2024-03-31
  • Polymédication et usage approprié des médicaments chez les aînés québécois, from 2021-07-01 to 2024-06-30
  • Primary care reform and medication appropriateness for seniors: A comparative study of two provinces, from 2018-04-01 to 2024-03-31
  • Projet GPS: Évaluation de l'impact de la réorganisation du travail en Groupe de médecine de famille (GMF) sur la Pharmacothérapie et le Soutien à l'autonomie des personnes âgées ayant un trouble neuro-cognitif majeur, from 2019-04-01 to 2023-06-30
  • Real-World Evaluation of the Efficacy, Safety and Cost-Effectiveness of Statins for Primary Prevention of Cardiovascular Disease Among the Elderly – A Causal Perspective to Treatment Trajectory Analysis, from 2019-10-01 to 2023-03-31
  • Suivi de la qualité de la pratique de l'électroconvulsivothérapie au Québec basé sur le recueil de données médico-administratives, cliniques et socio-démographiques en contexte réel, from 2020-01-01 to 2023-06-30

Recently finished projects

  • Chaire de recherche sur le vieillissement, from 2016-07-01 to 2021-12-14
  • La polypharmacie est-elle un risque pour la santé des aînés?, from 2020-03-17 to 2022-03-31
  • Maison des aînés : étude d'un modèle d'habitation innovant dans une perspective de relance de l'économie et de progrès de notre société suite à la pandémie de COVID-19., from 2021-04-01 to 2022-05-31
  • Portrait de la polypharmarcie et de la qualité des traitements des personnes âgées atteintes de schizophrénie au Québec: étude populationnelle de 2000 à 2018, from 2020-04-01 to 2021-03-31
  • Predicting population risk of suicide using health administrative data, from 2020-03-31 to 2022-03-30
Data provided by the Université Laval research projects registery