Skip to content

Scientific publications

  • article Ishaq A, Nawaz I, Qadir J, Alrokayan S, Hussain T, Gelsleichter NE, Pelletier J, Sévigny J, Muhammad M, Huang Q, Iqbal J

    Quinoline carboxylic acid derivatives as potent ectonucleotidase inhibitors

    Sci Rep 16 (1), 2026.

    DOI PUBMED
  • article Saidi A, Tollard C, Liu L, El Khallouqi Y, Sévigny J, Auger C, Kauffenstein G, Ghazouani FE, Kessler L, Toti F

    New Islet Model for 3D Study of Endothelial and β Cell Interactions: Relevance for the Screening of Cytoprotective Agents

    J Vis Exp (230), 2026.

    DOI PUBMED
  • article Batool Z, Dutt SM, Al-Rashida M, Gelsleichter NE, Pelletier J, Sévigny J, Islam T, Ismail MA, Khan A and Şenol H, Alharthy RD, Iqbal J, Shafiq Z

    Synthesis, biological evaluation and molecular docking studies of N-propylsulfonyl indole-linked hydrazinecarbothioamides as selective ecto-5-nucleotidase and NTPDase inhibitors

    Sci Rep 16 (1), 2026.

    DOI PUBMED
  • article Bi C, Schwermer F, Schäkel L, Mirza S, Baburi H, Riziki P, Schmies CC, Winzer R, Idris R, Rolshoven G, Schilling J, Luckenbach L, Pelletier J, Brusoni LS, Al Hroub H, Al Hamwi G, Lopez V, Ahmadsay A, Raulien L, Sylvester K, Sévigny J, Tolosa E, Guse AH, Müller CE

    Nucleotide-Derived Competitive Inhibitors of Ectonucleotidase CD39─A Promising Extracellular Target for Immunotherapy of Cancer

    J Med Chem 69 (9), 2026.

    DOI PUBMED
  • article da Silva JLG, Sévigny J, Leal DBR

    Nucleotide signaling in neutrophils: a key player in cancer dynamics

    Purinergic Signal 22 (3), 2026.

    DOI PUBMED
  • article Aftab H, Dutt SM, Mali SN, Vigiani E, Pelletier J, Sévigny J, Gurav SS, Jawarkar RD, Almalki AS, Akram MS, Batool Z, Schenone S, Iqbal J, Shafiq Z

    Synthesis, Biological Evaluation and Molecular Docking Studies of Novel 4-Propylsulfonylpiperazines-Based Thiosemicarbazones as Ecto-5-Nucleotidase and NTPDase Inhibitors

    Arch Pharm (Weinheim) 358 (9), 2025.

    DOI PUBMED
  • article Kelestemur T, Robson SC, Németh ZH, Pacher P, Arif M, Aydin MS, Suzek BE, Pelletier J, Lunsford KE, Schwabe RF, Geng Y, Sévigny J, Haskó G

    NTPDase8 Protects Against Liver Ischemia-Reperfusion Injury in Mice

    FASEB J 39 (13), 2025.

    DOI PUBMED
  • article Pinto-Cardoso R, Bessa-Andrês C, Pereira-Costa F, Neiva R, Martins-Ferreira R, Guerra-Leal B, Nóbrega Catelas D, Vilaça A, Oliveira A, Pelletier J, Sévigny J, Noronha-Matos JB, Correia-de-Sá P

    HIF-1α Stabilization Hampers the Chondrogenic Differentiation of Aged Bone Marrow Mesenchymal Stem Cells by Adenosine A2A/A2B Receptors Imbalance

    ACS Pharmacol Transl Sci 8 (7), 2025.

    DOI PUBMED
  • article Batool Z, Dutt SM, Al-Rashida M, Gelsleichter NE, Pelletier J, Sévigny J, Islam T, Aftab H, Almutairi TM and Çakır F, Shafiq Z, Iqbal J

    N-hexylsulfonyl indole based thiosemicarbazones as potent and selective ecto-5′-nucleotidase and NTPDase inhibitors

    Bioorg Chem 163 2025.

    DOI PUBMED
  • article Salarpour F, Sévigny J

    P2Y2 Receptor Signaling in Health and Disease

    Int J Mol Sci 26 (19), 2025.

    DOI PUBMED
  • article Silva LFL, Scholl JN, Weber AF, Dias CK, Pizzato PR, Lima VP, Sévigny J, Battastini AMO, Figueiró F

    Assessing the impact of CD73 inhibition on overcoming anti-EGFR resistance in glioma cells

    Oncol Res 33 (4), 2025.

    DOI PUBMED
  • article Manica FM, Campesato LFI, Scholl JN, Braganhol E, Bergamin LS, Edelweiss MIA, Lenz G, Sevigny J, Figueiró F, Battastini AMO

    Assessing Ecto-5′-Nucleotidase/CD73 Expression and Malignancy Parameters in Early- and Late- Passage C6 Glioma Cells

    Neurochem Res 50 (3), 2025.

    DOI PUBMED