Bringing together the expertise of multiple researchers, the Medicinal Chemistry Platform at the CHU de Québec-Université Laval Research Center offers cutting-edge services and world-class infrastructure for the development of new drugs.

To facilitate access to innovative research tools, all services are available to the entire research community. Whether you need design, optimization, or analysis of therapeutic candidates, our team is here to help turn your ideas into innovative solutions.

The platform provides rapid access to specialized expertise in medicinal chemistry, organic synthesis, peptide synthesis, and nanotechnology formulation. Additionally, flexible collaboration models are available to meet the specific needs of both academic and industrial partners.

List of Services Offered

Design and Synthesis of New Molecules
• Custom organic synthesis and chemical optimization
• Rational drug design (molecular modeling, docking, virtual screening)
• Compound library production for biological testing

Optimization of Drug-Like Properties
• ADME-Tox profiling and early pharmacokinetics
• Optimization of solubility, stability, and bioavailability
• Nanotechnology-based formulations to enhance therapeutic efficacy and drug delivery

Peptide Synthesis
• Synthesis of therapeutic peptides
• Optimization of physicochemical and pharmacokinetic properties of peptides

Advanced Molecular Analysis Services
• NMR spectroscopy (Nuclear Magnetic Resonance) for structural elucidation and compound purity analysis
• LC-MS mass spectrometry for molecular characterization and quantification
• FTIR spectroscopy for chemical bond analysis and structure confirmation

Collaboration and Scientific Support
• Personalized support for R&D projects (grant applications)
• Integration with biology and translational pharmacology platforms
• Flexible academic and industrial partnerships (service contracts, funded collaborations, co-development)

If you have a project in mind, do not hesitate to contact the Medicinal Chemistry Platform team for more information.

Contact
René Maltais, Ph.D.
418-654-2296, 418-525-4444 (ext. 46428)
Rene.maltais@crchudequebec.ulaval.ca

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