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2705, boulevard Laurier
R-4701.9
Québec, Québec
Canada G1V 4G2
CHUL
2705, boulevard Laurier
R-4720
Québec, Québec
Canada G1V 4G2
69 enregistrements « 1 de 7 »

Vaillancourt J, Turcotte V, Caron P, Villeneuve L, Lacombe L, Pouliot F, Levesque E, Guillemette C

Glucuronidation of Abiraterone and Its Pharmacologically Active Metabolites by UGT1A4, Influence of Polymorphic Variants and Their Potential as Inhibitors of Steroid Glucuronidation.

Article de revue

Drug Metab Dispos, 48 (2), p. 75-84, 2020, ISSN: 0090-9556.

Résumé | Liens:

Pouliot F, Rouleau M, Neveu B, Toren P, Morin F, Velot L, Ding K, Caron P, Lacombe L, Levesque E, Klotz L, Guillemette C

Extragonadal Steroids Contribute Significantly to the Androgen Receptor Activity and Castration Resistance Development in Recurrent Prostate Cancers after Primary Therapy.

Article de revue

J Urol, p. 101097JU0000000000000699, 2019, ISSN: 0022-5347.

Résumé | Liens:

Labriet A, Levesque E, Cecchin E, De Mattia E, Villeneuve L, Rouleau M, Jonker D, Couture F, Simonyan D, Allain EP, Buonadonna A, D'Andrea M, Toffoli G, Guillemette C

Germline variability and tumor expression level of ribosomal protein gene RPL28 are associated with survival of metastatic colorectal cancer patients.

Article de revue

Sci Rep, 9 (1), p. 13008, 2019, ISSN: 2045-2322.

Résumé | Liens:

Caron P, Turcotte V, Levesque E, Guillemette C

An LC-MS/MS method for quantification of abiraterone, its active metabolites D(4)-abiraterone (D4A) and 5α-abiraterone, and their inactive glucuronide derivatives.

Article de revue

J Chromatogr B Analyt Technol Biomed Life Sci, 1104 , p. 249-255, 2019, ISSN: 1570-0232.

Résumé | Liens:

Levesque E, Caron P, Lacombe L, Turcotte V, Simonyan D, Fradet Y, Aprikian A, Saad F, Carmel M, Chevalier S, Guillemette C

A Comprehensive Analysis of Steroid Hormones and Progression of Localized High-Risk Prostate Cancer.

Article de revue

Cancer Epidemiol Biomarkers Prev, 28 (4), p. 701-706, 2019, ISSN: 1055-9965.

Résumé | Liens:

Emond JP, Labriet A, Desjardins S, Rouleau M, Villeneuve L, Hovington H, Brisson H, Lacombe L, Simonyan D, Caron P, Perigny M, Tetu B, Fallon JK, Klein K, Smith PC, Zanger U, Guillemette C, Levesque E

Factors Affecting Interindividual Variability of Hepatic UGT2B17 Protein Expression Examined Using a Novel Specific Monoclonal Antibody.

Article de revue

Drug Metab Dispos, 47 (5), p. 444-452, 2019, ISSN: 0090-9556.

Résumé | Liens:

Allain EP, Rouleau M, Le T, Vanura K, Villeneuve L, Caron P, Turcotte V, Levesque E, Guillemette C

Inactivation of Prostaglandin E2 as a Mechanism for UGT2B17-Mediated Adverse Effects in Chronic Lymphocytic Leukemia.

Article de revue

Front Oncol, 9 , p. 606, 2019.

Résumé | Liens:

Labriet A, Levesque E, Mattia E, Cecchin E, Jonker D, Couture F, Simonyan D, Buonadonna A, D'Andrea M, Villeneuve L, Toffoli G, Guillemette C

Combination of germline variations associated with survival of folinic acid, fluorouracil and irinotecan-treated metastatic colorectal cancer patients.

Article de revue

Pharmacogenomics, 20 (17), p. 1179-1187, 2019, ISSN: 1462-2416.

Résumé | Liens:

De Mattia E, Polesel J, Roncato R, Labriet A, Bignucolo A, Dreussi E, Romanato L, Guardascione M, Buonadonna A, D'Andrea M, Levesque E, Jonker D, Couture F, Guillemette C, Cecchin E, Toffoli G

Germline Polymorphisms in the Nuclear Receptors PXR and VDR as Novel Prognostic Markers in Metastatic Colorectal Cancer Patients Treated With FOLFIRI.

Article de revue

Front Oncol, 9 , p. 1312, 2019.

Résumé | Liens:

Nazha S, Tanguay S, Kapoor A, Jewett M, Kollmannsberger C, Wood L, Bjarnason GAG, Heng D, Soulieres D, Reaume MN, Basappa N, Levesque E, Dragomir A

Cost-utility of Sunitinib Versus Pazopanib in Metastatic Renal Cell Carcinoma in Canada using Real-world Evidence.

Article de revue

Clin Drug Investig, 38 (12), p. 1155-1165, 2018, ISSN: 1173-2563.

Résumé | Liens:

69 enregistrements « 1 de 7 »
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Projets actifs

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, du 2017-01-01 au 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, du 1996-05-01 au 2023-04-30
  • The Contribution of Non-Classical 11-oxy Androgens to Prostate Cancer Progression, Subvention, Cancer de la prostate Canada, Subvention de découverte, du 2019-04-01 au 2021-03-31

Projets terminés récemment

  • Centre de recherche en endocrinologie, métabolisme et inflammation, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, du 1996-06-01 au 2018-04-30
  • Étude transbitionnelle pour évaluer l'activité de l'immunosupression sur la GUH, Subvention, Fondation du CHU de Québec, du 2014-05-01 au 2019-03-31
  • Function of the glucuronosyltransferase pathway in chronic lymphocytic leukemia, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, du 2017-04-01 au 2019-06-30
  • The role of serum steroids in the development of castrate resistant prostate cancer: a secondary analysis of the PR.7 trial, Subvention, Cancer de la prostate Canada, Subventions d'équipe Movember (Movember Discovery Grants), du 2016-07-01 au 2018-06-30
Information provenant du registre des projets de recherche de l'Université Laval