CHUL
2705, boulevard Laurier
R-4701.9
Québec, Québec
Canada G1V 4G2
CHUL
2705, boulevard Laurier
R-4720
Québec, Québec
Canada G1V 4G2
73 enregistrements « 1 de 8 »

Allain EP, Rouleau M, Vanura K, Tremblay S, Vaillancourt J, Bat V, Caron P, Villeneuve L, Labriet A, Turcotte V, Le T, Shehata M, Schnabl S, Demirtas D, Hubmann R, Joly-Beauparlant C, Droit A, Jager U, Staber PB, Levesque E, Guillemette C

UGT2B17 modifies drug response in chronic lymphocytic leukaemia.

Article de revue

Br J Cancer, 2020, ISSN: 0007-0920.

Résumé | Liens:

Carignan D, Lessard T, Villeneuve L, Desjardins S, Magnan S, Despres P, Martin AG, Foster W, Guillemette C, Levesque E, Vigneault E

DNA repair gene polymorphisms, tumor control, and treatment toxicity in prostate cancer patients treated with permanent implant prostate brachytherapy.

Article de revue

Prostate, 80 (8), p. 632-639, 2020, ISSN: 0270-4137.

Résumé | Liens:

Allain EP, Rouleau M, Levesque E, Guillemette C

Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression.

Article de revue

Br J Cancer, 122 (9), p. 1277-1287, 2020, ISSN: 0007-0920.

Résumé | Liens:

Levesque E, Labriet A, Hovington H, Allain EP, Melo-Garcia L, Rouleau M, Brisson H, Turcotte V, Caron P, Villeneuve L, Leclercq M, Droit A, Audet-Walsh E, Simonyan D, Fradet Y, Lacombe L, Guillemette C

Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression.

Article de revue

Br J Cancer, 122 (7), p. 1068-1076, 2020, ISSN: 0007-0920.

Résumé | Liens:

Vaillancourt J, Turcotte V, Caron P, Villeneuve L, Lacombe L, Pouliot F, Levesque E, Guillemette C

Glucuronidation of Abiraterone and Its Pharmacologically Active Metabolites by UGT1A4, Influence of Polymorphic Variants and Their Potential as Inhibitors of Steroid Glucuronidation.

Article de revue

Drug Metab Dispos, 48 (2), p. 75-84, 2020, ISSN: 0090-9556.

Résumé | Liens:

Pouliot F, Rouleau M, Neveu B, Toren P, Morin F, Velot L, Ding K, Caron P, Lacombe L, Levesque E, Klotz L, Guillemette C

Extragonadal Steroids Contribute Significantly to Androgen Receptor Activity and Development of Castration Resistance in Recurrent Prostate Cancer after Primary Therapy.

Article de revue

J Urol, 203 (5), p. 940-948, 2020, ISSN: 0022-5347.

Résumé | Liens:

Labriet A, Levesque E, Cecchin E, De Mattia E, Villeneuve L, Rouleau M, Jonker D, Couture F, Simonyan D, Allain EP, Buonadonna A, D'Andrea M, Toffoli G, Guillemette C

Germline variability and tumor expression level of ribosomal protein gene RPL28 are associated with survival of metastatic colorectal cancer patients.

Article de revue

Sci Rep, 9 (1), p. 13008, 2019, ISSN: 2045-2322.

Résumé | Liens:

Caron P, Turcotte V, Levesque E, Guillemette C

An LC-MS/MS method for quantification of abiraterone, its active metabolites D(4)-abiraterone (D4A) and 5α-abiraterone, and their inactive glucuronide derivatives.

Article de revue

J Chromatogr B Analyt Technol Biomed Life Sci, 1104 , p. 249-255, 2019, ISSN: 1570-0232.

Résumé | Liens:

Levesque E, Caron P, Lacombe L, Turcotte V, Simonyan D, Fradet Y, Aprikian A, Saad F, Carmel M, Chevalier S, Guillemette C

A Comprehensive Analysis of Steroid Hormones and Progression of Localized High-Risk Prostate Cancer.

Article de revue

Cancer Epidemiol Biomarkers Prev, 28 (4), p. 701-706, 2019, ISSN: 1055-9965.

Résumé | Liens:

Emond JP, Labriet A, Desjardins S, Rouleau M, Villeneuve L, Hovington H, Brisson H, Lacombe L, Simonyan D, Caron P, Perigny M, Tetu B, Fallon JK, Klein K, Smith PC, Zanger U, Guillemette C, Levesque E

Factors Affecting Interindividual Variability of Hepatic UGT2B17 Protein Expression Examined Using a Novel Specific Monoclonal Antibody.

Article de revue

Drug Metab Dispos, 47 (5), p. 444-452, 2019, ISSN: 0090-9556.

Résumé | Liens:

73 enregistrements « 1 de 8 »
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Projets actifs

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, du 2017-01-01 au 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, du 1996-05-01 au 2022-06-13
  • The Contribution of Non-Classical 11-oxy Androgens to Prostate Cancer Progression, Subvention, Cancer de la prostate Canada, Subvention de découverte, du 2019-04-01 au 2022-03-30

Projets terminés récemment

  • Function of the glucuronosyltransferase pathway in chronic lymphocytic leukemia, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, du 2017-04-01 au 2019-06-30
Information provenant du registre des projets de recherche de l'Université Laval