Scientific Publications

Ouled Amar Bencheikh B, Senkevich K, Rudakou U, Yu E, Mufti K, Ruskey JA, Asayesh F, Laurent SB, Spiegelman D, Fahn S, Waters C, Monchi O, Dauvilliers Y, Espay AJ, Dupre N, Greenbaum L, Hassin-Baer S, Rouleau GA, Alcalay RN, Fon EA, Gan-Or Z

Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson's disease.

Neurobiol Aging, 93 , pp. 143.e1-143.e4, 2020, ISSN: 0197-4580.

Abstract | Tags: Neuroscience | Links:

Gosselin D

Epigenomic and transcriptional determinants of microglial cell identity.

Glia, 68 (8), pp. 1643-1654, 2020, ISSN: 0894-1491.

Abstract | Tags: Neuroscience | Links:

Le Blanc G, Jette Pomerleau V, McCarthy J, Borroni B, van Swieten J, Galimberti D, Sanchez-Valle R, LaForce R Jr, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Vandenberghe R, Finger E, Tagliavini F, de Mendonca A, Santana I, Butler C, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Sorbi S, Rohrer JD, Ducharme S, GENetic Frontotemporal dementia Initiative (GENFI)

Faster Cortical Thinning and Surface Area Loss in Presymptomatic and Symptomatic C9orf72 Repeat Expansion Adult Carriers.

Ann Neurol, 88 (1), pp. 113-122, 2020, ISSN: 0364-5134.

Abstract | Tags: Neuroscience | Links:

Picher-Martel V, Brunet F, Dupre N, Chrestian N

The Occurrence of FUS Mutations in Pediatric Amyotrophic Lateral Sclerosis: A Case Report and Review of the Literature.

J Child Neurol, 35 (8), pp. 556-562, 2020, ISSN: 0883-0738.

Abstract | Tags: Neuroscience | Links:

Maxan A, Sciacca G, Alpaugh M, Tao Z, Breger L, Dehay B, Ling Z, Qin C, Cisbani G, Masnata M, Salem S, Lacroix S, Oueslati A, Bezard E, Cicchetti F

Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates.

Neurobiol Dis, 141 , pp. 104951, 2020, ISSN: 0969-9961.

Abstract | Tags: Neuroscience | Links:

Gosset P, Maxan A, Alpaugh M, Breger L, Dehay B, Tao Z, Ling Z, Qin C, Cisbani G, Fortin N, Vonsattel JG, Lacroix S, Oueslati A, Bezard E, Cicchetti F

Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates.

Neurobiol Dis, 141 , pp. 104941, 2020, ISSN: 0969-9961.

Abstract | Tags: Neuroscience | Links:

Bartl S, Oueslati A, Southwell AL, Siddu A, Parth M, David LS, Maxan A, Salhat N, Burkert M, Mairhofer A, Friedrich T, Pankevych H, Balazs K, Staffler G, Hayden MR, Cicchetti F, Smrzka OW

Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease.

Neurobiol Dis, 141 , pp. 104943, 2020, ISSN: 0969-9961.

Abstract | Tags: Neuroscience | Links:

Ross JP, Leblond CS, Laurent SB, Spiegelman D, Dionne-Laporte A, Camu W, Dupre N, Dion PA, Rouleau GA

Oligogenicity, C9orf72 expansion, and variant severity in ALS.

Neurogenetics, 21 (3), pp. 227-242, 2020, ISSN: 1364-6745.

Abstract | Tags: Neuroscience | Links:

Seidman JS, Troutman TD, Sakai M, Gola A, Spann NJ, Bennett H, Bruni CM, Ouyang Z, Li RZ, Sun X, Vu BT, Pasillas MP, Ego KM, Gosselin D, Link VM, Chong LW, Evans RM, Thompson BM, McDonald JG, Hosseini M, Witztum JL, Germain RN, Glass CK

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis.

Immunity, 52 (6), pp. 1057-1074.e7, 2020, ISSN: 1074-7613.

Abstract | Tags: Neuroscience | Links:

Sharma K, Tremblay ME

Microglia: Multiple states and multiple roles in the normal and diseased brain and spinal cord.

Neurosci Lett, 729 , pp. 135019, 2020, ISSN: 0304-3940.

Tags: Neuroscience | Links:

Hodgkinson V, Oskoui M, Lounsberry J, M'Dahoma S, Butler E, Campbell C, MacKenzie A, McMillan H, Simard L, Vajsar J, Brais B, Chapman K, Chrestian N, Crone M, Dobrowolski P, Dojeiji S, Dowling JJ, Dupre N, Genge A, Gonorazky H, Hasal S, Izenberg A, Johnston W, Leung E, Lochmuller H, Mah JK, Marerro A, Massie R R, McAdam L, McCormick A, Melanson M, Mezei MM, Nguyen CE, O'Connell C, O'Ferrall E, Pfeffer G, Phan C, Plamondon S, Poulin C, Rodrigue X, Schellenberg K, Selby K, Sheriko J, Shoesmith C, Smith G, Taillon M, Taylor S, Warman J, Worley S, Korngut L

A national spinal muscular atrophy registry for real world evidence.

Can J Neurol Sci, pp. 1-18, 2020, ISSN: 0317-1671.

Tags: Neuroscience | Links:

Hamadjida A, Sid-Otmane L, Kwan C, Frouni I, Nafade V, Bedard D, Gagnon D, Wallman MJ, Rouillard C, Parent A, Parent M, Huot P

The highly selective mGlu2 receptor positive allosteric modulator LY-487,379 alleviates l-DOPA-induced dyskinesia in the 6-OHDA-lesioned rat model of Parkinson's disease.

Eur J Neurosci, 51 (12), pp. 2412-2422, 2020, ISSN: 0953-816X.

Abstract | Tags: Neuroscience | Links:

Ducharme S, Dols A, Laforce R, Devenney E, Kumfor F, van den Stock J, Dallaire-Theroux C, Seelaar H, Gossink F, Vijverberg E, Huey E, Vandenbulcke M, Masellis M, Trieu C, Onyike C, Caramelli P, de Souza LC, Santillo A, Waldo ML, Landin-Romero R, Piguet O, Kelso W, Eratne D, Velakoulis D, Ikeda M, Perry D, Pressman P, Boeve B, Vandenberghe R, Mendez M, Azuar C, Levy R, Le Ber I, Baez S, Lerner A, Ellayosyula R, Pasquier F, Galimberti D, Scarpini E, van Swieten J, Hornberger M, Rosen H, Hodges J, Diehl-Schmid J, Pijnenburg Y

Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders.

Brain, 143 (6), pp. 1632-1650, 2020, ISSN: 0006-8950.

Abstract | Tags: Neuroscience | Links:

van der Ende EL, Xiao M, Xu D, Poos JM, Panman JL, Jiskoot LC, Meeter LH, Dopper EG, Papma JM, Heller C, Convery R, Moore K, Bocchetta M, Neason M, Peakman G, Cash DM, Teunissen CE, Graff C, Synofzik M, Moreno F, Finger E, Sanchez-Valle R, Vandenberghe R, Laforce R Jr, Masellis M, Tartaglia MC, Rowe JB, Butler CR, Ducharme S, Gerhard A, Danek A, Levin J, Pijnenburg YA, Otto M, Borroni B, Tagliavini F, de Mendonca A, Santana I, Galimberti D, Seelaar H, Rohrer JD, Worley PF, van Swieten JC, Genetic Frontotemporal Dementia Initiative (GENFI)

Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia.

J Neurol Neurosurg Psychiatry, 91 (6), pp. 612-621, 2020, ISSN: 0022-3050.

Abstract | Tags: Neuroscience | Links:

Girardet L, Bernet A, Calvo E, Soulet D, Joly-Beauparlant C, Droit A, Cyr DG, Belleannee C

Hedgehog signaling pathway regulates gene expression profile of epididymal principal cells through the primary cilium.

FASEB J, 34 (6), pp. 7593-7609, 2020, ISSN: 0892-6638.

Abstract | Tags: Endocrinology and nephrology, Neuroscience, Reproduction, mother and youth health | Links:

Zukotynski K, Gaudet V, Kuo PH, Adamo S, Goubran M, Scott CJM, Bocti C, Borrie M, Chertkow H, Frayne R, Hsiung R, Laforce R Jr, Noseworthy MD, Prato FS, Sahlas DJ, Smith EE, Sossi V, Thiel A, Soucy JP, Tardif JC, Black SE

The Use of Random Forests to Identify Brain Regions on Amyloid and FDG PET Associated With MoCA Score.

Clin Nucl Med, 45 (6), pp. 427-433, 2020, ISSN: 0363-9762.

Abstract | Tags: Neuroscience | Links:

Aubry-Lafontaine E, Tremblay C, Durand-Martel P, Dupre N, Frasnelli J

Orthonasal, but not Retronasal Olfaction Is Specifically Impaired in Parkinson's Disease.

Chem Senses, 45 (5), pp. 401-406, 2020, ISSN: 0379-864X.

Abstract | Tags: Neuroscience | Links:

Stratton A, Wai E, Kingwell S, Phan P, Roffey D, El Koussy M, Christie S, Jarzem P, Rasoulinejad P, Casha S, Paquet J, Johnson M, Abraham E, Hall H, McIntosh G, Thomas K, Rampersaud R, Manson N, Fisher C

Opioid use trends in patients undergoing elective thoracic and lumbar spine surgery.

Can J Surg, 63 (3), pp. E306-E312, 2020, ISSN: 0008-428X.

Abstract | Tags: Neuroscience | Links:

Martel C, Tsutsumi T, Cement V, Khuong HT, Dupre N, Ismail AA, Gros-Louis F

Diagnosis of idiopathic amyotrophic lateral sclerosis using Fourier-transform infrared spectroscopic analysis of patient-derived skin.

Analyst, 145 (10), pp. 3678-3685, 2020, ISSN: 0003-2654.

Abstract | Tags: Neuroscience, Regenerative medecine | Links:

Luo X, Guet-McCreight A, Villette V, Francavilla R, Marino B, Chamberland S, Skinner FK, Topolnik L

Synaptic Mechanisms Underlying the Network State-Dependent Recruitment of VIP-Expressing Interneurons in the CA1 Hippocampus.

Cereb Cortex, 30 (6), pp. 3667-3685, 2020, ISSN: 1047-3211.

Abstract | Tags: Neuroscience | Links:

Boyadzhiev A, Trevithick-Sutton C, Wu D, Decan N, Bazin M, Shah GM, Halappanavar S

Enhanced Dark-Field Hyperspectral Imaging and Spectral Angle Mapping for Nanomaterial Detection in Consumer Care Products and in Skin Following Dermal Exposure.

Chem Res Toxicol, 33 (5), pp. 1266-1278, 2020, ISSN: 0893-228X.

Abstract | Tags: Neuroscience | Links:

Chan V, Nataraj A, Bailey C, Abraham E, Soroceanu A, Johnson M, Paquet J, Christie S, Stratton A, Hall H, Manson N, Rampersaud YR, Thomas K, Fisher C

Comparison of Clinical Outcomes Between Posterior Instrumented Fusion With and Without Interbody Fusion for Isthmic Spondylolisthesis.

Clin Spine Surg, 2020, ISSN: 2380-0186.

Abstract | Tags: Neuroscience | Links:

Luo X, Guet-McCreight A, Villette V, Francavilla R, Marino B, Chamberland S, Skinner FK, Topolnik L

Corrigendum: Synaptic Mechanisms Underlying the Network State-Dependent Recruitment of VIP-Expressing Interneurons in the CA1 Hippocampus.

Cereb Cortex, 30 (5), pp. 3437, 2020, ISSN: 1047-3211.

Tags: Neuroscience | Links:

Manto M, Dupre N, Hadjivassiliou M, Louis ED, Mitoma H, Molinari M, Shaikh AG, Soong BW, Strupp M, Van Overwalle F, Schmahmann JD

Management of Patients with Cerebellar Ataxia During the COVID-19 Pandemic: Current Concerns and Future Implications.

Cerebellum, 2020, ISSN: 1473-4222.

Abstract | Tags: Neuroscience | Links:

Mishra PS, Boutej H, Soucy G, Bareil C, Kumar S, Picher-Martel V, Dupre N, Kriz J, Julien JP

Transmission of ALS pathogenesis by the cerebrospinal fluid.

Acta Neuropathol Commun, 8 (1), pp. 65, 2020, ISSN: 2051-5960.

Abstract | Tags: Neuroscience | Links:

Bendok BR, Abi-Aad KR, Ward JD, Kniss JF, Kwasny MJ, Rahme RJ, Aoun SG, El Ahmadieh TY, El Tecle NE, Zammar SG, Aoun RJN, Patra DP, Ansari SA, Raymond J, Woo HH, Fiorella D, Dabus G, Milot G, Delgado Almandoz JE, Scott JA, DeNardo AJ, Dashti SR, HEAT Study Investigators

The Hydrogel Endovascular Aneurysm Treatment Trial (HEAT): A Randomized Controlled Trial of the Second-Generation Hydrogel Coil.

Neurosurgery, 86 (5), pp. 615-624, 2020, ISSN: 0148-396X.

Abstract | Tags: Neuroscience | Links:

Matovic S, Ichiyama A, Igarashi H, Salter EW, Sunstrum JK, Wang XF, Henry M, Kuebler ES, Vernoux N, Martinez-Trujillo J, Tremblay ME, Inoue W

Neuronal hypertrophy dampens neuronal intrinsic excitability and stress responsiveness during chronic stress.

J Physiol, 2020, ISSN: 0022-3751.

Abstract | Tags: Neuroscience | Links:

Dufort-Gervais J, Provost C, Charbonneau L, Norris CM, Calon F, Mongrain V, Brouillette J

Neuroligin-1 is altered in the hippocampus of Alzheimer's disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers.

Sci Rep, 10 (1), pp. 6956, 2020, ISSN: 2045-2322.

Abstract | Tags: Neuroscience | Links:

Guisle I, Gratuze M, Petry S, Morin F, Keraudren R, Whittington RA, Hebert SS, Mongrain V, Planel E

Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature.

Sleep, 43 (4), 2020, ISSN: 0161-8105.

Abstract | Tags: Neuroscience | Links:

Evaniew N, Cadotte DW, Dea N, Bailey CS, Christie SD, Fisher CG, Paquet J, Soroceanu A, Thomas KC, Rampersaud YR, Manson NA, Johnson M, Nataraj A, Hall H, McIntosh G, Jacobs WB

Clinical predictors of achieving the minimal clinically important difference after surgery for cervical spondylotic myelopathy: an external validation study from the Canadian Spine Outcomes and Research Network.

J Neurosurg Spine, pp. 1-9, 2020, ISSN: 1547-5654.

Abstract | Tags: Neuroscience | Links:

Schlachetzki JCM, Prots I, Tao J, Chun HB, Saijo K, Gosselin D, Winner B, Glass CK, Winkler J

Author Correction: A monocyte gene expression signature in the early clinical course of Parkinson's disease.

Sci Rep, 10 (1), pp. 6261, 2020, ISSN: 2045-2322.

Abstract | Tags: Neuroscience | Links:

Savage JC, St-Pierre MK, Carrier M, El Hajj H, Novak SW, Sanchez MG, Cicchetti F, Tremblay ME

Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington's disease pathology.

J Neuroinflammation, 17 (1), pp. 98, 2020.

Abstract | Tags: Neuroscience | Links:

Adant S, Shah GM, Beauregard JM

Combination treatments to enhance peptide receptor radionuclide therapy of neuroendocrine tumours.

Eur J Nucl Med Mol Imaging, 47 (4), pp. 907-921, 2020, ISSN: 1619-7070.

Abstract | Tags: Neuroscience, Oncology | Links:

Krohn L, Wu RY, Heilbron K, Ruskey JA, Laurent SB, Blauwendraat C, Alam A, Arnulf I, Hu MTM, Dauvilliers Y, Hogl B, Toft M, Bjornara KA, Stefani A, Holzknecht E, Monaca CC, Beatriz A, Plazzi G, Antelmi E, Ferini-Strambi L, Young P, Heidbreder A, Cochen De Cock V, Mollenhauer B, Sixel-Doring F, Trenkwalder C, Sonka K, Kemlink D, Figorilli M, Puligheddu M, Dijkstra F, Viaene M, Oertel W, Toffoli M, Gigli GL, Valente M, Gagnon JF, Nalls MA, Singleton AB, 23andMe Research Team, Desautels A, Montplaisir JY, Cannon P, Ross OA, Boeve BF, Dupre N, Fon EA, Postuma RB, Pihlstrom L, Rouleau GA, Gan-Or Z

Fine-Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies.

Ann Neurol, 87 (4), pp. 584-598, 2020, ISSN: 0364-5134.

Abstract | Tags: Neuroscience | Links:

Pellerin D, Aykanat A, Ellezam B, Troiano EC, Karamchandani J, Dicaire MJ, Petitclerc M, Robertson R, Allard-Chamard X, Brunet D, Konersman CG, Mathieu J, Warman Chardon J, Gupta VA, Beggs AH, Brais B, Chrestian N

Novel Recessive TNNT1 Congenital Core-Rod Myopathy in French Canadians.

Ann Neurol, 87 (4), pp. 568-583, 2020, ISSN: 0364-5134.

Abstract | Tags: Neuroscience | Links:

Soulet D, Lamontagne-Proulx J, Aube B, Davalos D

Multiphoton intravital microscopy in small animals: motion artefact challenges and technical solutions.

J Microsc, 278 (1), pp. 3-17, 2020, ISSN: 0022-2720.

Abstract | Tags: Neuroscience | Links:

Canizares M, Glennie RA, Perruccio AV, Abraham E, Ahn H, Attabib N, Christie S, Johnson MG, Nataraj A, Nicholls F, Paquet J, Phan P, Rasoulinejad P, Manson N, Hall H, Thomas K, Fisher CG, Rampersaud YR

Erratum to 'Patients' expectations of spine surgery for degenerative conditions: results from the Canadian Spine Outcomes and Research Network (CSORN)'. [Spine J. 2020;20(3):399-408].

Spine J, 20 (4), pp. 674, 2020, ISSN: 1529-9430.

Tags: Neuroscience | Links:

Bazin M, Purohit NK, Merlin MA, Shah GM

A panel of criteria for comprehensive assessment of severity of ultraviolet B radiation-induced non-melanoma skin cancers in SKH-1 mice.

J Photochem Photobiol B, 205 , pp. 111847, 2020, ISSN: 1011-1344.

Abstract | Tags: Neuroscience | Links:

Anwar S, Rivest S

Alzheimer's disease: microglia targets and their modulation to promote amyloid phagocytosis and mitigate neuroinflammation.

Expert Opin Ther Targets, 24 (4), pp. 331-344, 2020, ISSN: 1472-8222.

Abstract | Tags: Neuroscience | Links:

Beaudin M, Sellami L, Martel C, Touzel-Deschenes L, Houle G, Martineau L, Lacroix K, Lavallee A, Chrestian N, Rouleau GA, Gros-Louis F, Laforce R Jr, Dupre N

Characterization of the phenotype with cognitive impairment and protein mislocalization in SCA34.

Neurol Genet, 6 (2), pp. e403, 2020, ISSN: 2376-7839.

Abstract | Tags: Neuroscience, Regenerative medecine | Links:

Berube M, Moore L, Leduc S, Farhat I, Lesieur M, Lamontagne J, Pelet S, Berry G, Tardif PA, Cote C, Paquet J

Low-value injury care in the adult orthopaedic trauma population: a protocol for a rapid review.

BMJ Open, 10 (3), pp. e033453, 2020.

Abstract | Tags: Neuroscience, Other researches, Populations health and optimal health practices | Links:

Garofalo S, Picard K, Limatola C, Nadjar A, Pascual O, Tremblay ME

Role of Glia in the Regulation of Sleep in Health and Disease.

Compr Physiol, 10 (2), pp. 687-712, 2020, ISSN: 2040-4603.

Abstract | Tags: Neuroscience | Links:

Pradeep Yeola A, Akbar I, Baillargeon J, Mercy Ignatius Arokia Doss P, Paavilainen VO, Rangachari M

Protein translocation and retro-translocation across the endoplasmic reticulum are crucial to inflammatory effector CD4+ T cell function.

Cytokine, 129 , pp. 154944, 2020, ISSN: 1043-4666.

Abstract | Tags: Neuroscience | Links:

Canizares M, Gleenie A, Perruccio A, Abraham E, Ahn H, Attabib N, Christie S, Johnson MG, Nataraj A, Nicolls F, Paquet J, Phan P, Rasoulinejad P, Manson N, Hall H, Thomas K, Fisher CG, Rampersaud R

Patients' expectations of spine surgery for degenerative conditions: results from the Canadian Spine Outcomes and Research Network (CSORN).

Spine J, 20 (3), pp. 399-408, 2020, ISSN: 1529-9430.

Abstract | Tags: Neuroscience | Links:

Bouchard AE, Dickler M, Renauld E, Lenglos C, Ferland F, Edden RA, Rouillard C, Leblond J, Fecteau S

The impact of brain morphometry on tDCS effects on GABA levels.

Brain Stimul, 13 (2), pp. 284-286, 2020, ISSN: 1876-4754.

Tags: Neuroscience | Links:

Bordeleau M, Carrondo Cottin S, Cantin L, Gaudin D, Alnemari A, Canuel JF, Fugere F, Fournier-Gosselin MP, Vollert J, Prud'homme M

Effects of Tonic Spinal Cord Stimulation on External Mechanical and Thermal Stimuli Perception Using Quantitative Sensory Testing: A Multicenter Stimulation ON-OFF Study on Chronic Pain Patients.

Clin J Pain, 36 (3), pp. 189-196, 2020, ISSN: 0749-8047.

Abstract | Tags: Neuroscience | Links:

Beaulieu LD, Schneider C, Masse-Alarie H, Ribot-Ciscar E

A new method to elicit and measure movement illusions in stroke by means of muscle tendon vibration: the Standardized Kinesthetic Illusion Procedure (SKIP).

Somatosens Mot Res, 37 (1), pp. 28-36, 2020, ISSN: 0899-0220.

Abstract | Tags: Neuroscience | Links:

Estiar MA, Leveille E, Spiegelman D, Dupre N, Trempe JF, Rouleau GA, Gan-Or Z

Clinical and genetic analysis of ATP13A2 in hereditary spastic paraplegia expands the phenotype.

Mol Genet Genomic Med, 8 (3), pp. e1052, 2020.

Abstract | Tags: Neuroscience | Links:

Heller C, Foiani MS, Moore K, Convery R, Bocchetta M, Neason M, Cash DM, Thomas D, Greaves CV, Woollacott IO, Shafei R, Van Swieten JC, Moreno F, Sanchez-Valle R, Borroni B, Laforce R Jr, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Frisoni G, Sorbi S, Otto M, Heslegrave AJ, Zetterberg H, Rohrer JD, GENFI

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.

J Neurol Neurosurg Psychiatry, 91 (3), pp. 263-270, 2020, ISSN: 0022-3050.

Abstract | Tags: Neuroscience | Links:

Auclair-Ouellet N, Fossard M, Macoir J, Laforce R Jr

The Nonverbal Processing of Actions Is an Area of Relative Strength in the Semantic Variant of Primary Progressive Aphasia.

J Speech Lang Hear Res, 63 (2), pp. 569-584, 2020, ISSN: 1092-4388.

Abstract | Tags: Neuroscience, Populations health and optimal health practices | Links: