Scientific Publications

Gratuze M, Josset N, Petry FR, Pflieger M, Jong LE, Truchetti G, Poitras I, Julien J, Bezeau F, Morin F, Samadi P, Cicchetti F, Bretzner F, Planel E

The toxin MPTP generates similar cognitive and locomotor deficits in hTau and tau knock-out mice.

Brain Res, 1711 , pp. 106-114, 2019, ISSN: 0006-8993.

Abstract | Tags: Neuroscience | Links:

Tremblay ME, Cookson MR, Civiero L

Glial phagocytic clearance in Parkinson's disease.

Mol Neurodegener, 14 (1), pp. 16, 2019.

Abstract | Tags: Neuroscience | Links:

Phan P, Budhram B, Zhang Q, Rivers C, Noonan VK, Plashkes T, Wai EK, Paquet J, Roffey DM, Tsai E, Fallah N, RHSCIR Network

Highlighting discrepancies in walking prediction accuracy for patients with traumatic spinal cord injury: an evaluation of validated prediction models using a Canadian Multicenter Spinal Cord Injury Registry.

Spine J, 19 (4), pp. 703-710, 2019, ISSN: 1529-9430.

Abstract | Tags: Neuroscience | Links:

Lamontagne-Proulx J, St-Amour I, Labib R, Pilon J, Denis HL, Cloutier N, Roux-Dalvai F, Vincent AT, Mason SL, Duchez AC, Droit A, Lacroix S, Dupre N, Langlois M, Chouinard S, Panisset M, Barker RA, Boilard E, Cicchetti F

Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease.

Neurobiol Dis, 124 , pp. 163-175, 2019, ISSN: 0969-9961.

Abstract | Tags: Endocrinology and nephrology, Infectious and immune diseases, Neuroscience | Links:

Fournier S, Boukari R, Chamberland S, Bretzner F, Joseph V, Kinkead R

Distinct dampening effects of progesterone on the activity of nucleus tractus solitarii neurons in rat pups.

Exp Physiol, 104 (4), pp. 463-468, 2019, ISSN: 0958-0670.

Abstract | Tags: Neuroscience, Reproduction, mother and youth health | Links:

Premi E, Calhoun VD, Diano M, Gazzina S, Cosseddu M, Alberici A, Archetti S, Paternico D, Gasparotti R, van Swieten J, Galimberti D, Sanchez-Valle R, Laforce R Jr, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe J, Vandenberghe R, Finger E, Tagliavini F, de Mendonca A, Santana I, Butler C, Ducharme S, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Cappa S, Sorbi S, Padovani A, Rohrer JD, Borroni B, Genetic FTD Initiative, GENFI

The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint.

Neuroimage, 189 , pp. 645-654, 2019, ISSN: 1053-8119.

Abstract | Tags: Neuroscience | Links:

Tournissac M, Bourassa P, Martinez-Cano RD, Vu TM, Hebert SS, Planel E, Calon F

Repeated cold exposures protect a mouse model of Alzheimer's disease against cold-induced tau phosphorylation.

Mol Metab, 22 , pp. 110-120, 2019, ISSN: 2212-8778.

Abstract | Tags: Neuroscience | Links:

Mutsaerts HJMM, Mirza SS, Petr J, Thomas DL, Cash DM, Bocchetta M, de Vita E, Metcalfe AWS, Shirzadi Z, Robertson AD, Tartaglia MC, Mitchell SB, Black SE, Freedman M, Tang-Wai D, Keren R, Rogaeva E, van Swieten J, Laforce R, Tagliavini F, Borroni B, Galimberti D, Rowe JB, Graff C, Frisoni GB, Finger E, Sorbi S, de Mendonca A, Rohrer JD, MacIntosh BJ, Masellis M, GENFI consortium

Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study.

Brain, 142 (4), pp. 1108-1120, 2019, ISSN: 0006-8950.

Abstract | Tags: Neuroscience | Links:

Close AF, Dadheech N, Villela BS, Rouillard C, Buteau J

The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass.

J Biol Chem, 294 (13), pp. 4889-4897, 2019, ISSN: 0021-9258.

Abstract | Tags: Neuroscience | Links:

Boscher E, Husson T, Quenez O, Laquerriere A, Marguet F, Cassinari K, Wallon D, Martinaud O, Charbonnier C, Nicolas G, Deleuze JF, Boland A, Lathrop M, Frebourg T, FREX Consortium, Campion D, Hebert SS, Rovelet-Lecrux A

Copy Number Variants in miR-138 as a Potential Risk Factor for Early-Onset Alzheimer's Disease.

J Alzheimers Dis, 2019, ISSN: 1387-2877.

Abstract | Tags: Neuroscience | Links:

Bourque M, Morissette M, Di Paolo T

Repurposing sex steroids and related drugs as potential treatment for Parkinson's disease.

Neuropharmacology, 147 , pp. 37-54, 2019, ISSN: 0028-3908.

Abstract | Tags: Neuroscience | Links:

Gasparini F, Di Paolo T

Drug repurposing: Old drugs, new tricks to fast track drug development for the brain.

Neuropharmacology, 147 , pp. 1-3, 2019, ISSN: 0028-3908.

Tags: Neuroscience | Links:

Becker Y, Loignon RC, Julien AS, Marcoux G, Allaeys I, Levesque T, Rollet-Labelle E, Benk-Fortin H, Cloutier N, Melki I, Eder L, Wagner E, Pelletier M, Hajj HE, Tremblay ME, Belleannee C, Hebert MJ, Dieude M, Rauch J, Fortin PR, Boilard E

Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestations.

Sci Rep, 9 (1), pp. 4530, 2019, ISSN: 2045-2322.

Abstract | Tags: Infectious and immune diseases, Neuroscience, Reproduction, mother and youth health | Links:

Moore L, Lauzier F, Tardif PA, Boukar KM, Farhat I, Archambault P, Mercier E, Lamontagne F, Chasse M, Stelfox HT, Berthelot S, Gabbe B, Lecky F, Yanchar N, Champion H, Kortbeek J, Cameron P, Bonaventure PL, Paquet J, Truchon C, Turgeon AF, Canadian Traumatic brain injury Research Consortium

LOW-VALUE CLINICAL PRACTICES IN INJURY CARE: A SCOPING REVIEW AND EXPERT CONSULTATION SURVEY.

J Trauma Acute Care Surg, 2019.

Abstract | Tags: Neuroscience, Populations health and optimal health practices | Links:

Jean LeBlanc N, Menet R, Picard K, Parent G, Tremblay ME, ElAli A

Canonical Wnt Pathway Maintains Blood-Brain Barrier Integrity upon Ischemic Stroke and Its Activation Ameliorates Tissue Plasminogen Activator Therapy.

Mol Neurobiol, 2019, ISSN: 0893-7648.

Abstract | Tags: Neuroscience | Links:

Denis HL, Lauruol F, Cicchetti F

Are immunotherapies for Huntington's disease a realistic option?

Mol Psychiatry, 24 (3), pp. 364-377, 2019, ISSN: 1359-4184.

Abstract | Tags: Neuroscience | Links:

Whittington RA, Virag L, Gratuze M, Lewkowitz-Shpuntoff H, Cheheltanan M, Petry F, Poitras I, Morin F, Planel E

Administration of the benzodiazepine midazolam increases tau phosphorylation in the mouse brain.

Neurobiol Aging, 75 , pp. 11-24, 2019, ISSN: 0197-4580.

Abstract | Tags: Neuroscience | Links:

Skuk D, Tremblay JP

Myotubes Formed De Novo by Myoblasts Injected into the Scar of Myocardial Infarction Persisted for 16 Years in a Patient: Importance for Regenerative Medicine in Degenerative Myopathies.

Stem Cells Transl Med, 8 (3), pp. 313-314, 2019, ISSN: 2157-6564.

Tags: Neuroscience | Links:

Hui CW, Bhardwaj SK, Sharma K, Joseph AT, Bisht K, Picard K, Tremblay ME, Srivastava LK

Microglia in the developing prefrontal cortex of rats show dynamic changes following neonatal disconnection of the ventral hippocampus.

Neuropharmacology, 146 , pp. 264-275, 2019, ISSN: 0028-3908.

Abstract | Tags: Neuroscience | Links:

Cury C, Durrleman S, Cash DM, Lorenzi M, Nicholas JM, Bocchetta M, van Swieten JC, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni GB, Laforce R Jr, Finger E, de Mendonca A, Sorbi S, Ourselin S, Rohrer JD, Modat M, Genetic FTD Initiative, GENFI

Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: Initial application to the GENFI cohort.

Neuroimage, 188 , pp. 282-290, 2019, ISSN: 1053-8119.

Abstract | Tags: Neuroscience | Links:

Lal BK, Roubin GS, Jones M, Clark W, Mackey A, Hill MD, Voeks JH, Howard G, Hobson RW 2nd, Brott TG

Influence of multiple stents on periprocedural stroke after carotid artery stenting in the Carotid Revascularization Endarterectomy versus Stent Trial (CREST).

J Vasc Surg, 69 (3), pp. 800-806, 2019, ISSN: 0741-5214.

Abstract | Tags: Neuroscience | Links:

Denis HL, Lamontagne-Proulx J, St-Amour I, Mason SL, Rowley JW, Cloutier N, Tremblay ME, Vincent AT, Gould PV, Chouinard S, Weyrich AS, Rondina MT, Barker RA, Boilard E, Cicchetti F

Platelet abnormalities in Huntington's disease.

J Neurol Neurosurg Psychiatry, 90 (3), pp. 272-283, 2019, ISSN: 0022-3050.

Abstract | Tags: Infectious and immune diseases, Neuroscience | Links:

Giguere-Rancourt A, Plourde M, Doiron M, Langlois M, Dupre N, Simard M

Goal management training ® home-based approach for mild cognitive impairment in Parkinson's disease: a multiple baseline case report.

Neurocase, pp. 1-11, 2019, ISSN: 1355-4794.

Abstract | Tags: Neuroscience | Links:

Alcalay RN, Mallett V, Vanderperre B, Tavassoly O, Dauvilliers Y, Wu RYJ, Ruskey JA, Leblond CS, Ambalavanan A, Laurent SB, Spiegelman D, Dionne-Laporte A, Liong C, Levy OA, Fahn S, Waters C, Kuo SH, Chung WK, Ford B, Marder KS, Kang UJ, Hassin-Baer S, Greenbaum L, Trempe JF, Wolf P, Oliva P, Zhang XK, Clark LN, Langlois M, Dion PA, Fon EA, Dupre N, Rouleau GA, Gan-Or Z

SMPD1 mutations, activity, and α-synuclein accumulation in Parkinson's disease.

Mov Disord, 2019, ISSN: 0885-3185.

Abstract | Tags: Neuroscience | Links:

Masnata M, Sciacca G, Maxan A, Bousset L, Denis HL, Lauruol F, David L, Saint-Pierre M, Kordower JH, Melki R, Alpaugh M, Cicchetti F

Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms.

Acta Neuropathol, 2019, ISSN: 0001-6322.

Abstract | Tags: Neuroscience | Links:

Cunin P, Lee PY, Kim E, Schmider AB, Cloutier N, Pare A, Gunzer M, Soberman RJ, Lacroix S, Boilard E, Lefort CT, Nigrovic PA

Differential attenuation of β2 integrin-dependent and -independent neutrophil migration by Ly6G ligation.

Blood Adv, 3 (3), pp. 256-267, 2019, ISSN: 2473-9529.

Abstract | Tags: Infectious and immune diseases, Neuroscience | Links:

Bourassa P, Tremblay C, Schneider JA, Bennett DA, Calon F

Beta-amyloid pathology in human brain microvessel extracts from the parietal cortex: relation with cerebral amyloid angiopathy and Alzheimer's disease.

Acta Neuropathol, 2019, ISSN: 0001-6322.

Abstract | Tags: Neuroscience | Links:

Bourassa P, Alata W, Tremblay C, Paris-Robidas S, Calon F

Transferrin Receptor-Mediated Uptake at the Blood-Brain Barrier Is Not Impaired by Alzheimer's Disease Neuropathology.

Mol Pharm, 16 (2), pp. 583-594, 2019, ISSN: 1543-8384.

Abstract | Tags: Neuroscience | Links:

Macoir J, Hudon C, Tremblay MP, Laforce RJ, Wilson MA

The contribution of semantic memory to the recognition of basic emotions and emotional valence: Evidence from the semantic variant of primary progressive aphasia.

Soc Neurosci, pp. 1-12, 2019, ISSN: 1747-0919.

Abstract | Tags: Neuroscience, Populations health and optimal health practices | Links:

Lavoie M, Bier N, Laforce R Jr, Macoir J

Improvement in functional vocabulary and generalization to conversation following a self-administered treatment using a smart tablet in primary progressive aphasia.

Neuropsychol Rehabil, pp. 1-31, 2019, ISSN: 0960-2011.

Abstract | Tags: Neuroscience, Populations health and optimal health practices | Links:

Rieux M, Alpaugh M, Cicchetti F

The troubling story of blood-driven dementias.

Mol Psychiatry, 24 (2), pp. 162-166, 2019, ISSN: 1359-4184.

Tags: Neuroscience | Links:

Topolnik L, Camire O

Non-linear calcium signalling and synaptic plasticity in interneurons.

Curr Opin Neurobiol, 54 , pp. 98-103, 2019, ISSN: 0959-4388.

Abstract | Tags: Neuroscience | Links:

Bordeleau M, Carrondo Cottin S, Meier K, Prud'Homme M

Effects of Tonic Spinal Cord Stimulation on Sensory Perception in Chronic Pain Patients: A Systematic Review.

Neuromodulation, 22 (2), pp. 149-162, 2019, ISSN: 1094-7159.

Abstract | Tags: Neuroscience | Links:

Bourcier R, Lindgren A, Desal H, L'Allinec V, Januel AC, Koivisto T, Jaaskelainen JE, Slot EMH, Mensing L, Zuithoff NPA, Milot G, Algra A, Rinkel GJE, Ruigrok Y

Concordance in Aneurysm Size at Time of Rupture in Familial Intracranial Aneurysms.

Stroke, 50 (2), pp. 504-506, 2019, ISSN: 0039-2499.

Abstract | Tags: Neuroscience | Links:

Schafer ST, Paquola ACM, Stern S, Gosselin D, Ku M, Pena M, Kuret TJM, Liyanage M, Mansour AA, Jaeger BN, Marchetto MC, Glass CK, Mertens J, Gage FH

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons.

Nat Neurosci, 22 (2), pp. 243-255, 2019, ISSN: 1097-6256.

Abstract | Tags: Neuroscience | Links:

Pinto M, Zorn KC, Tremblay JP, Desroches J, Dallaire F, Aubertin K, Marple E, Kent C, Leblond F, Trudel D, Lesage F

Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures.

J Biomed Opt, 24 (2), pp. 1-10, 2019, ISSN: 1083-3668.

Abstract | Tags: Neuroscience, Oncology | Links:

Bellver-Landete V, Bretheau F, Mailhot B, Vallieres N, Lessard M, Janelle ME, Vernoux N, Tremblay ME, Fuehrmann T, Shoichet MS, Lacroix S

Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury.

Nat Commun, 10 (1), pp. 518, 2019, ISSN: 2041-1723.

Abstract | Tags: Neuroscience | Links:

Nichols MR, St-Pierre MK, Wendeln AC, Makoni NJ, Gouwens LK, Garrad EC, Sohrabi M, Neher JJ, Tremblay ME, Combs CK

Inflammatory mechanisms in neurodegeneration.

J Neurochem, 2019, ISSN: 0022-3042.

Abstract | Tags: Neuroscience | Links:

Magnin E, Francavilla R, Amalyan S, Gervais E, Suzanne David L, Luo X, Topolnik L

Input-Specific Synaptic Location and Function of the α5 GABAA Receptor Subunit in the Mouse CA1 Hippocampal Neurons.

J Neurosci, 39 (5), pp. 788-801, 2019, ISSN: 0270-6474.

Abstract | Tags: Neuroscience | Links:

Steuer I, Guertin PA

Central pattern generators in the brainstem and spinal cord: an overview of basic principles, similarities and differences.

Rev Neurosci, 30 (2), pp. 107-164, 2019, ISSN: 0334-1763.

Abstract | Tags: Neuroscience | Links:

Srinivas S, Paquet J, Bailey C, Nataraj A, Stratton A, Johnson M, Salo P, Christie S, Fisher C, Hall H, Manson N, Rampersaud YR, Thomas K, McIntosh G, Dea N

Effect of spinal decompression on back pain in lumbar spinal stenosis: a Canadian Spine Outcomes Research Network (CSORN) study.

Spine J, 2019, ISSN: 1529-9430.

Abstract | Tags: Neuroscience | Links:

St-Amour I, Bosoi CR, Pare I, Ignatius Arokia Doss PM, Rangachari M, Hebert SS, Bazin R, Calon F

Peripheral adaptive immunity of the triple transgenic mouse model of Alzheimer's disease.

J Neuroinflammation, 16 (1), pp. 3, 2019.

Abstract | Tags: Neuroscience | Links:

Rittman T, Borchert R, Jones S, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Graff C, Tagliavini F, Frisoni GB, Laforce R Jr, Finger E, Mendonca A, Sorbi S, Rohrer JD, Rowe JB, Genetic Frontotemporal Dementia Initiative (GENFI)

Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia.

Neurobiol Aging, 77 , pp. 169-177, 2019, ISSN: 0197-4580.

Abstract | Tags: Neuroscience | Links:

Ailon T, Tee J, Manson N, Hall H, Thomas K, Rampersaud YR, Yee A, Dea N, Glennie A, Bailey C, Christie S, Weber MH, Nataraj A, Paquet J, Johnson M, Norton J, Ahn H, McIntosh G, Fisher CG

Patient-reported outcomes following surgery for degenerative spondylolitshtesis: comparison of a universal and multitier health care system.

Spine J, 19 (1), pp. 24-33, 2019, ISSN: 1529-9430.

Abstract | Tags: Neuroscience | Links:

Rudakou U, Ouled Amar Bencheikh B, Ruskey JA, Krohn L, Laurent SB, Spiegelman D, Liong C, Fahn S, Waters C, Monchi O, Fon EA, Dauvilliers Y, Alcalay RN, Dupre N, Gan-Or Z

Common and rare GCH1 variants are associated with Parkinson's disease.

Neurobiol Aging, 73 , pp. 231.e1-231.e6, 2019, ISSN: 0197-4580.

Abstract | Tags: Neuroscience | Links:

Masse-Alarie H, Bergin M, Schneider C, Schabrun S, Hodges P

Reply to the comment on: "Reporting matters: Brain mapping with transcranial magnetic stimulation".

Hum Brain Mapp, 40 (1), pp. 354-355, 2019, ISSN: 1065-9471.

Tags: Neuroscience | Links:

Skuk D, Tremblay JP

Sarcolemmal Complement Membrane Attack Complex Deposits During Acute Rejection of Myofibers in Nonhuman Primates.

J Neuropathol Exp Neurol, 78 (1), pp. 38-46, 2019, ISSN: 0022-3069.

Abstract | Tags: Neuroscience | Links:

Chamberland S, Zamora Moratalla A, Topolnik L

Calcium extrusion mechanisms in dendrites of mouse hippocampal CA1 inhibitory interneurons.

Cell Calcium, 77 , pp. 49-57, 2019, ISSN: 0143-4160.

Abstract | Tags: Neuroscience | Links:

Foveau B, Correia AS, Hebert SS, Rainone S, Potvin O, Kergoat MJ, Belleville S, Duchesne S, LeBlanc AC, and the CIMA-Q Consortium for the early identification of Alzheimer's

Stem Cell-Derived Neurons as Cellular Models of Sporadic Alzheimer's Disease.

J Alzheimers Dis, 67 (3), pp. 893-910, 2019, ISSN: 1387-2877.

Abstract | Tags: Neuroscience | Links:

Rancourt A, Sato S, Satoh MS

Dose-dependent spatiotemporal responses of mammalian cells to an alkylating agent.

PLoS ONE, 14 (3), pp. e0214512, 2019.

Abstract | Tags: Infectious and immune diseases, Neuroscience | Links: