Dr. Ze Zhang received his B.Eng. and M.Eng. in 1982 and 1984 from Chengdu University of Science & Technology (now Sichuan University) and then his PhD degree in Experimental Medicine from Laval University in 1993. After a postdoctoral training in Japan, he returned to Laval University in 1995 and later became a professor in the Department of Surgery of the School of Medicine, and a researcher at the CHU de Québec-Laval University Research Center Division of Regenerative Medicine. Dr. Zhang’s research has been funded by the Canadian Institutes of Health Research (CIHR), Natural Sciences and Engineering Research Council of Canada (NSERC), Fonds de la recherche en santé du Québec (FRSQ), and industrial partners. He has more than one hundred journal publications, has edited one book, and authored several book chapters.
Dr. Zhang is interested in biomaterials, wound healing, and cardiovascular devices.
Electrical stimulation for wound healing
Electrical interactions are ubiquitous in biological systems and play pivotal roles in molecular recognition and signal transduction. In collaboration with Dr. Mahmoud Rouabhia, Dr. Zhang develops electrically conductive biomaterials and uses them as scaffold or substrate to mediate electrical stimulation to cells. The electrically activated cells are studied for their behaviors, activation mechanisms, and potential in wound healing. Research approaches include material preparation, cell culture, biological analysis, and animal experiments.
Electrically conductive polymers are useful as semi-conductors and in the energy harvesting and storage sectors. However, such polymers are usually poor in mechanical properties, processability and functionality. Dr. Zhang’s lab focusses on the nano-structured conductive polymers with improved properties and functionalities. Research approaches include polymer synthesis, surface modification, and material analysis.
Cardiovascular devices, implants, and materials
The safety and quality of cardiovascular implants such as vascular prostheses and heart valves are critical to patients. In collaboration with Drs. Yvan Douville and Robert Guidoin, Dr. Zhang has a long-term research interest in the development of new cardiovascular devices, the analysis of clinically retrieved medical explants, and the study of new materials for medical applications. Research approaches include in vitro tests, animal experiments, material analysis, and polymer synthesis.
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Corrigendum to "Potential of a facile sandwiched electrospun scaffold loaded with ibuprofen as an anti-adhesion barrier" [Mater. Sci. Eng. C 118 (2021) 111451].Journal Article
Mater Sci Eng C Mater Biol Appl, 129 , 2021.
Effects of electrical stimulation on human skin keratinocyte growth and the secretion of cytokines and growth factors.Journal Article
Biomed Mater, 2021.
Customized and in situ fenestrated stent-grafts: A reinforced poly-ε-caprolactone branch cuff designed to prevent type III endoleaks and enhance hemodynamicsJournal Article
Med Nov Technol Devices, 9 , 2021.
Flexible and free-standing pristine polypyrrole membranes with a nanotube structure for repeatable Cr(VI) ion removalJournal Article
Sep Purif Technol, 258 , 2021.
Ultra-low temperature flexible supercapacitor based on hierarchically structured pristine polypyrrole membranesJournal Article
Chem Eng J, 420 , 2021, ISSN: 1385-8947.
Effect of Electrical Stimulation on Diabetic Human Skin Fibroblast Growth and the Secretion of Cytokines and Growth Factors Involved in Wound Healing.Journal Article
Biology (Basel), 10 (7), 2021.
Potential of a facile sandwiched electrospun scaffold loaded with ibuprofen as an anti-adhesion barrier.Journal Article
Mater Sci Eng C Mater Biol Appl, 118 , 2021.
Optimal In Situ Fenestration Technique With Laser Perforation and Balloon Dilation for Aortic Stent-Grafts.Journal Article
J Endovasc Ther, 28 (2), 2021.
Commentary: Honing the Technique of In Situ Stent-Graft Fenestration.Journal Article
J Endovasc Ther, 28 (1), 2021.
Facile fabrication of phospholipid-functionalized nanofiber-based barriers with enhanced anti-adhesion efficiency.Journal Article
Colloids Surf B Biointerfaces, 203 , 2021.
- Centre de recherche sur les systèmes polymères et composites à haute performance (CREPEC), from 2015-04-01 to 2022-03-31
- Engineering cannabis-loaded hydrogels/emulsions to treat inflammatory tissue diseases, from 2021-05-31 to 2024-05-30
- Flexible conductive polymer membranes, from 2017-04-01 to 2022-03-31
Recently finished projects
- Cell Response and Wound Healing Through Electrical Stimulation Mediated by Conductive Scaffold, from 2016-07-01 to 2021-06-30