Dr Yves Fradet graduated from Laval University (Quebec, Canada) in 1981 and completed an oncology fellowship at the Memorial Sloan-Kettering Cancer Center, with Drs Willet Whitmore and Lloyd Old. In 1983 he founded, at the Laval University Cancer Research Center, a translational and clinical research laboratory  in urological cancers whose work are supported continuously for more than 30 years.

Dr Fradet still has a very active practice in uro-Oncology within the Urologic Oncology Section and the Urology Service at the CHU de Québec- Hôtel-Dieu de Québec where he has grouped a team of specialists among the most important in Canada including seven uro-oncologists, three of which are also holders of PhD.

He is a member of many national and international societies, including since 2001, the American Association of Genitourinary Surgeons in which he was invited to be part of the 75 members in America. More recently, he was appointed international honorary member of the Association of Academic European Urology, membership awarded to those who have had important influence on urology. Dr Fradet is often invited as a guest speaker at national and international meetings, as a visiting professor, and as a consultant to many organizations. He was the founding chairman of the Canadian Urologic Oncology Group from 1988 to 1995 and chairman of the Department of Surgery at Laval University from 2000 to 2008. He has authored over 330 publications and book chapters and more than 600 abstracts.

L'Hôtel-Dieu de Québec
10, rue McMahon
1853-1
Québec, Québec
Canada G1R 2J6
310 entries « 2 of 31 »

Haider M, Ladurner C, Mayr R, Tandogdu Z, Fritsche HM, Fradet V, Comploj E, Pycha A, Lemire F, Lacombe L, Fradet Y, Toren P, Lodde M

Use and duration of antibiotic prophylaxis and the rate of urinary tract infection after radical cystectomy for bladder cancer: Results of a multicentric series.

Journal Article

Urol Oncol, 37 (5), pp. 300.e9-300.e15, 2019, ISSN: 1078-1439.

Abstract | Links:

Leclercq M, Vittrant B, Martin-Magniette ML, Scott Boyer MP, Perin O, Bergeron A, Fradet Y, Droit A

Large-Scale Automatic Feature Selection for Biomarker Discovery in High-Dimensional OMICs Data.

Journal Article

Front Genet, 10 , pp. 452, 2019, ISSN: 1664-8021.

Abstract | Links:

Joncas FH, Lucien F, Rouleau M, Morin F, Leong HS, Pouliot F, Fradet Y, Gilbert C, Toren P

Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients.

Journal Article

Prostate, 79 (15), pp. 1767-1776, 2019, ISSN: 0270-4137.

Abstract | Links:

Nguile-Makao M, Allard MA, Bairati I, Meyer F, Robitaille K, Fradet Y, Lacombe L, Pouliot F, Toren P, Duchesne T, Fradet V

Charlson Comorbidity Index as a Predictor of Cancer Mortality Beyond 10 Years after Radical Prostatectomy

Journal Article

Clin Oncol (Belmont), 4 , pp. 1638 (5 pages), 2019.

McMartin C, Lacombe L, Fradet V, Fradet Y, Lodde M, Toren P

Receipt of 5-Alpha Reductase Inhibitors Before Radical Cystectomy: Do They Render High-Grade Bladder Tumors Less Aggressive?

Journal Article

Clin Genitourin Cancer, 17 (6), pp. e1122-e1128, 2019, ISSN: 1558-7673.

Abstract | Links:

Houlahan KE, Shiah YJ, Gusev A, Yuan J, Ahmed M, Shetty A, Ramanand SG, Yao CQ, Bell C, O'Connor E, Huang V, Fraser M, Heisler LE, Livingstone J, Yamaguchi TN, Rouette A, Foucal A, Espiritu SMG, Sinha A, Sam M, Timms L, Johns J, Wong A, Murison A, Orain M, Picard V, Hovington H, Bergeron A, Lacombe L, Lupien M, Fradet Y, Tetu B, McPherson JD, Pasaniuc B, Kislinger T, Chua MLK, Pomerantz MM, van der Kwast T, Freedman ML, Mani RS, He HH, Bristow RG, Boutros PC

Genome-wide germline correlates of the epigenetic landscape of prostate cancer.

Journal Article

Nat Med, 25 (10), pp. 1615-1626, 2019, ISSN: 1078-8956.

Abstract | Links:

Toren P, Hoffman A, Ding K, Joncas FH, Turcotte V, Caron P, Pouliot F, Fradet Y, Levesque E, Guillemette C, Klotz LH

Serum Sex Steroids as Prognostic Biomarkers in Patients Receiving Androgen Deprivation Therapy for Recurrent Prostate Cancer: A Post Hoc Analysis of the PR.7 Trial.

Journal Article

Clin Cancer Res, 24 (21), pp. 5305-5312, 2018, ISSN: 1078-0432.

Abstract | Links:

Joseph JV, Brasacchio R, Fung C, Reeder J, Bylund K, Sahasrabudhe D, Yeh SY, Ghazi A, Fultz P, Rubens D, Wu G, Singer E, Schwarz E, Mohile S, Mohler J, Theodorescu D, Lee YF, Okunieff P, McConkey D, Rashid H, Chang C, Fradet Y, Guru K, Kukreja J, Sufrin G, Lotan Y, Bailey H, Noyes K, Schwartz S, Rideout K, Bratslavsky G, Campbell SC, Derweesh I, Abrahamsson PA, Soloway M, Gomella L, Golijanin D, Svatek R, Frye T, Lerner S, Palapattu G, Wilding G, Droller M, Trump D

A Festschrift in Honor of Edward M. Messing, MD, FACS.

Journal Article

Bladder Cancer, 4 (Suppl 1), pp. S1-S43, 2018, ISSN: 2352-3727.

| Links:

Locke JA, Hamidizadeh R, Kassouf W, Ricardo Rendon R, Bell D, Izawa J, Joseph Chin J, Kapoor A, Shayegen B, Lattouf JB, Saad F, Lacombe L, Fradet Y, Fairey A, Jacobson NE, Drachenberg D, Cagiannos I, So A, Black PC

Surveillance guidelines based on recurrence patterns for upper tract urothelial carcinoma.

Journal Article

Can Urol Assoc J, 12 (8), pp. 243-251, 2018, ISSN: 1911-6470.

Abstract | Links:

Kassouf W, Aprikian A, Saad F, Breau RH, Kulkarni G, Guttman DM, Bagshaw K, Izawa J, Eapen L, Fairey A, So A, North S, Rendon R, Sridhar SS, Brimo F, Chung P, Drachenberg D, Fradet Y, Jacobsen N, Morash C, Shayegan B, Gotto G, Zlotta A, Fleshner N, Siemens DR, Black PC

Improving patient journey and quality of care: Summary from the second Bladder Cancer Canada-Canadian Urological Association-Canadian Urologic Oncology Group (BCC-CUA-CUOG) bladder cancer quality of care consensus meeting.

Journal Article

Can Urol Assoc J, 12 (7), pp. E281-E297, 2018, ISSN: 1911-6470.

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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
  • Interaction between environment, diet, physical activities, and sexual habits, in the risk of prostate cancer. Validation of biomarkers to personnalize preventive interventions., Subvention, Société de recherche sur le cancer, Compétition GRePEC (SRC/FRSQ/MDEIE), from 2012-10-01 to 2020-08-31
  • Prebiotics to enhance immunotherapy response in bladder cancer, Subvention, The W. Garfield Weston Foundation, 2018 Proof-of-Principle Grant Call, from 2019-01-01 to 2020-07-31
  • Stromal Gene Expression Predicts And May Drive Metastasis in Prostate Cancer, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2017-04-01 to 2022-03-31
  • Toward nutritional and epigenomic interventions in prostate cancer prevention and management, Subvention, Instituts de recherche en santé du Canada, Fonctionnement: Subvention de promotion de l’impact - CCREES, from 2017-10-01 to 2020-09-30

Recently finished projects

  • (FRSQ 83876)Targeting PD-1 and TIGIT pathways for the immunotherapy of bladder cancer, Subvention, Association canadienne d'urologie, from 2018-11-23 to 2019-11-22
  • (FRSQ 83897) Inducing prostate tumor eosinophilia to favor prostate cancer immunotherapy , Subvention, Canadian Urological Association Scholarship Foundation, CUA Astellas Research Grant Program 2017, from 2018-06-19 to 2019-06-18
  • (FRSQ 84899) Financement de la phase 1 du projet de recherche DPX-SurMAGE, Subvention, Fondation du CHU de Québec, from 2019-03-25 to 2020-03-24
  • Combination of Wnt-ß-catenin, androgen receptor and PD-1 inhibition for the therapy of bladder cancer, Subvention, Cancer de la vessie Canada, Research Grant Program 2017, from 2018-01-01 to 2018-12-31
  • Development of a urine-based prostate cancer cell bioluminescence imaging nanotechnology for single cell transcriptional characterization, Subvention, Société de recherche sur le cancer, Subvention de fonctionnement, from 2016-09-01 to 2018-08-31
  • Development of bladder cancer immunotherapy., Subvention, L'Institut de recherche de la Société canadienne du cancer, Subventions pour un impact, from 2013-02-01 to 2019-01-31
  • Effects of the Leucocytic Infiltration of Intraductal Carcinoma of the Prostate, Partenariat, Société de recherche sur le cancer, Subvention de fonctionnement, from 2017-09-01 to 2019-08-31
  • Effet de la thérapie combinant un anti-PD-1 et le tasquinimod pour le traitement du cancer de la prostate, Subvention, Université Laval - Soutien à la recherche, from 2018-05-01 to 2019-04-30
  • Enhancing bladder cancer immunotherapy efficacy in men using bicalutamide, Subvention, Société de recherche sur le cancer, from 2018-12-01 to 2019-11-30
  • Tranexamic acid during cystectomy trial (TACT), Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2015-07-01 to 2018-06-30
Data provided by the Université Laval research projects registery