Dr. Vincent Fradet (MD, PhD, FRCSC) is an uro-oncologist with a focused clinical practice at CHU de Québec-Laval University. He completed his medical training at Université de Montréal with an MD and residency in urology. He pursued with 5 years of subspecialty and research training. He obtained his uro-oncology accreditation from the Society of Urologic Oncology at the University of California, in San Francisco (UCSF) and completed a PhD in Clinical Research/Epidemiolgy (University de Montréal). Dr. Fradet has been an Associate Professor at Laval University since 2009, and is a regular researcher at the Laval University Cancer Research Center and at INAF (Institute for Nutrition and functional Food).

Dr. Fradet’s research goal is to improve our understanding of the links between lifestyle factors, including dietary omega-3 fatty acids and exercise, quality of life parameters, inflammation, and oncogenic pathways in prostate cancer, to progressively develop personalized preventive and treatment strategies. To that end, Dr. Fradet has built a unique biobank of bio-samples, developed pre-clinical models (mouse and primary cells in culture) and is running some clinical studies. All the epidemiological, clinical, and molecular (translational) projects led by his team are focused on improving our understanding of the biological mechanisms and the impact on quality of life of prostate cancer, as well as on developing biomarkers (urinary, blood, epigenetics, molecular and/or cellular) to be used in future intervention studies to stratify or select and monitor patients.

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Trudel D, Labbe DP, Bairati I, Fradet V, Bazinet L, Tetu B

Green tea for ovarian cancer prevention and treatment: a systematic review of the in vitro, in vivo and epidemiological studies.

Journal Article

Gynecol Oncol, 126 (3), pp. 491-8, 2012, ISSN: 0090-8258.

Abstract | Links:

Audet-Walsh E, Bellemare J, Lacombe L, Fradet Y, Fradet V, Douville P, Guillemette C, Levesque E

The impact of germline genetic variations in hydroxysteroid (17-beta) dehydrogenases on prostate cancer outcomes after prostatectomy.

Journal Article

Eur Urol, 62 (1), pp. 88-96, 2012, ISSN: 0302-2838.

Abstract | Links:

Audet-Walsh E, Bellemare J, Nadeau G, Lacombe L, Fradet Y, Fradet V, Huang SP, Bao BY, Douville P, Girard H, Guillemette C, Levesque E

SRD5A polymorphisms and biochemical failure after radical prostatectomy.

Journal Article

Eur Urol, 60 (6), pp. 1226-34, 2011, ISSN: 0302-2838.

Abstract | Links:

Fradet V, Kurhanewicz J, Cowan JE, Karl A, Coakley FV, Shinohara K, Carroll PR

Prostate cancer managed with active surveillance: role of anatomic MR imaging and MR spectroscopic imaging.

Journal Article

Radiology, 256 (1), pp. 176-83, 2010, ISSN: 0033-8419.

Abstract | Links:

Odisho AY, Cooperberg MR, Fradet V, Ahmad AE, Carroll PR

Urologist density and county-level urologic cancer mortality.

Journal Article

J Clin Oncol, 28 (15), pp. 2499-504, 2010, ISSN: 0732-183X.

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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2022-06-13
  • Institut sur la nutrition et les aliments fonctionnels (INAF), Subvention, Fonds de recherche du Québec - Nature et technologies, Regroupements stratégiques NT, from 2017-04-01 to 2024-03-31
  • Interaction between environment, diet, physical activities, and sexual habits, in the risk of prostate cancer. Validation of biomarkers to personnalize preventive interventions., Subvention, Société de recherche sur le cancer, Compétition GRePEC (SRC/FRSQ/MDEIE), from 2012-10-01 to 2020-08-31
  • Nutrition, santé et société (NUTRISS), Subvention, Fonds de recherche du Québec - Santé, Nouveaux Centres et Instituts de recherche - Subventions régulières, from 2019-04-01 to 2024-03-31
  • Toward nutritional and epigenomic interventions in prostate cancer prevention and management, Subvention, Instituts de recherche en santé du Canada, Fonctionnement: Subvention de promotion de l’impact - CCREES, from 2017-10-01 to 2020-09-30

Recently finished projects

  • (FRSQ 85605) Plateforme méthodologique du CRCEO (statistiques uro-oncologie) , Subvention, Fondation du CHU de Québec, from 2019-05-30 to 2020-05-29
  • Détresse et satisfactions face au processus informationnel et décisionnel lors d'un cancer de la prostate localisé, Subvention, Fondation de l'Université Laval, from 2017-02-01 to 2020-03-31
  • Impact of microbiota on prostate cancer: from gut to tumor microenvironment., Subvention, Centre hospitalier universitaire de Montréal, from 2018-12-01 to 2019-12-31
  • Plateforme méthodologique du Centre de Recherche Clinique et Evaluative en Oncoloie (CRCEO) uro-oncologie, Subvention, Fondation du CHU de Québec, from 2019-03-05 to 2020-03-04
  • Prebiotics to enhance immunotherapy response in bladder cancer, Subvention, The W. Garfield Weston Foundation, 2018 Proof-of-Principle Grant Call, from 2019-01-01 to 2020-07-31
  • Projet de recherche CaptoMD : Cancer de la prostate, Subvention, Fondation du CHU de Québec, from 2019-03-22 to 2020-03-21
  • Rôle du microbiote intestinal dans le cancer de la prostate, Subvention, Université Laval - Soutien à la recherche, from 2018-05-01 to 2019-04-30
Data provided by the Université Laval research projects registery