Dr. Vincent Fradet (MD, PhD, FRCSC) is an uro-oncologist with a focused clinical practice at CHU de Québec-Laval University. He completed his medical training at Université de Montréal with an MD and residency in urology. He pursued with 5 years of subspecialty and research training. He obtained his uro-oncology accreditation from the Society of Urologic Oncology at the University of California, in San Francisco (UCSF) and completed a PhD in Clinical Research/Epidemiolgy (University de Montréal). Dr. Fradet has been an Associate Professor at Laval University since 2009, and is a regular researcher at the Laval University Cancer Research Center and at INAF (Institute for Nutrition and functional Food).
Dr. Fradet’s research goal is to improve our understanding of the links between lifestyle factors, including dietary omega-3 fatty acids and exercise, quality of life parameters, inflammation, and oncogenic pathways in prostate cancer, to progressively develop personalized preventive and treatment strategies. To that end, Dr. Fradet has built a unique biobank of bio-samples, developed pre-clinical models (mouse and primary cells in culture) and is running some clinical studies. All the epidemiological, clinical, and molecular (translational) projects led by his team are focused on improving our understanding of the biological mechanisms and the impact on quality of life of prostate cancer, as well as on developing biomarkers (urinary, blood, epigenetics, molecular and/or cellular) to be used in future intervention studies to stratify or select and monitor patients.
6, rue McMahon
0622
Québec, Québec
Canada G1R 2J6
Latest news
- Beaudoin, LisanneMaster studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15055+1 418-691-2958lisanne.beaudoin.1@ulaval.calisanne.beaudoin@crchudequebec.ulaval.ca
6, rue McMahon
Québec, Québec
Canada G1R 3S3 - Ben Souilah, FarahDoctoral studentL'Hôtel-Dieu de Québecfarah.ben-souilah@crchudequebec.ulaval.ca
6 Rue McMahon
0602
Québec, QC
Canada G1R 3S1 - Desrochers-Goyette, JustineMaster studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16849justine.desrochers-goyette@crchudequebec.ulaval.ca
10, McMahon
0885
Québec, QC
Canada G1R 3S1 - Diabaté, LamoussaDoctoral studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15532lamoussa.diabate.1@ulaval.calamoussa.diabate@crchudequebec.ulaval.ca
6, rue McMahon
0617
Québec, Québec
Canada G1R 3S3 - Gendron-Courchesne, ClaudiaEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 21629claudia.gendron-courchesne@crchudequebec.ulaval.ca
6 Rue McMahon
0680
Québec, QC
Canada G1R 3S1 - Kone, Amenan Prisca NadègePostdoctoral fellow+1 418-525-4444, extension 15055amenan-prisca-nadege.kone@crchudequebec.ulaval.ca
- Laaraj, JalalDoctoral studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15160jalal.laaraj@crchudequebec.ulaval.ca
6 Rue McMahon
0885
Québec, QC
Canada G1R 3S1 - Lachance, GabrielEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15055gabriel.lachance@crchudequebec.ulaval.ca
10 Rue Mcmahon
0880
Québec, QC
Canada G1R 3S1 - Molina, Oscar EduardoEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16849+1 418-691-5562oscar-eduardo.molina.1@ulaval.caoscar-eduardo.molina@crchudequebec.ulaval.ca
10, rue McMahon
1875
Québec, Québec
Canada G1R 2J6 - Moussa, HananeDoctoral studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15158+1 418-691-5562hanane.moussa.1@ulaval.cahanane.moussa@crchudequebec.ulaval.ca
6, rue McMahon
0620
Québec, Québec
Canada G1R 3S1 - Moussa, HananeMaster studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15158+1 418-691-5562hanane.moussa.1@ulaval.cahanane.moussa@crchudequebec.ulaval.ca
6, rue McMahon
0620
Québec, Québec
Canada G1R 3S1 - Pelletier, Jean-FrançoisEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15158+1 418-691-5562jean-francois.pelletier@crchudequebec.ulaval.ca
6, rue McMahon
0620
Québec, Québec
Canada G1R 2J6 - Robitaille, KarineEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 16841+1 418-691-5562Karine.Robitaille.2@crchudequebec.ulaval.ca
10, rue McMahon
1852-1
Québec, Québec
Canada G1R 2J6 - Rosebush-Mercier, RaphaëllaEmployeeL'Hôtel-Dieu de Québec+1 418-525-4444, extension 21629raphaella.rosebush-mercier@crchudequebec.ulaval.ca
6 Rue McMahon
0680
Québec, QC
Canada G1R 3S1 - Sarrazin, CharlineEmployeeL'Hôtel-Dieu de Québeccharline.sarrazin@crchudequebec.ulaval.ca
6 Rue Mcmahon
0602
Québec, QC
Canada G1R 3S1 - Tourigny, RoxaneMaster studentHôpital Saint-Sacrement
1050 Chemin Sainte-Foy
J1-12
Québec, QC
Canada G1S 4L8L'Hôtel-Dieu de Québec+1 418-525-4444, extension 15158roxane.tourigny@crchudequebec.ulaval.ca
6 McMahon
0602
Québec, Québec
Canada G1R 2J6 - Tremblay, AnthonyUndergraduate studentL'Hôtel-Dieu de Québec+1 418-525-4444, extension 15532anthony.tremblay.6@ulaval.caanthony.tremblay@crchudequebec.ulaval.ca
6, rue McMahon
0617
Québec, Québec
Canada G1R 3S1
Omega-3 Eicosapentaenoic Acid Reduces Prostate Tumor Vascularity.
Journal ArticleMol Cancer Res, 19 (3), pp. 516-527, 2021, ISSN: 1541-7786.
Long chain omega-3 fatty acids and their oxidized metabolites are associated with reduced prostate tumor growth.
Journal ArticleProstaglandins Leukot Essent Fatty Acids, 164 , pp. 102215, 2021, ISSN: 0952-3278.
Real-world evidence in patient-reported outcomes (PROs) of metastatic castrate-resistant prostate cancer (mCRPC) patients treated with abiraterone acetate + prednisone (AA+P) across Canada: Final results of COSMiC.
Journal ArticleCan Urol Assoc J, 14 (12), pp. E616-E620, 2020, ISSN: 1911-6470.
Psychological morbidity associated with prostate cancer: Rates and predictors of depression in the RADICAL PC study.
Journal ArticleCan Urol Assoc J, 2020, ISSN: 1911-6470.
Building a Canadian Translational Bladder Cancer Research Network.
Journal ArticleCan Urol Assoc J, 14 (10), pp. E475-E481, 2020, ISSN: 1911-6470.
Neutrophil-to-lymphocyte Ratio as a Predictive Marker of Response to Abiraterone Acetate: A Retrospective Analysis of the COU302 Study.
Journal ArticleEur Urol Oncol, 3 (3), pp. 298-305, 2020, ISSN: 2588-9311.
Cardiovascular Risk in Men with Prostate Cancer: Insights from the RADICAL PC Study.
Journal ArticleJ Urol, 203 (6), pp. 1109-1116, 2020, ISSN: 0022-5347.
Omega-3 Fatty Acids Survey in Men under Active Surveillance for Prostate Cancer: from Intake to Prostate Tissue Level.
Journal ArticleNutrients, 11 (7), 2019, ISSN: 2072-6643.
Increased Prostate Cancer Glucose Metabolism Detected by 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Localised Gleason 8-10 Prostate Cancers Identifies Very High-risk Patients for Early Recurrence and Resistance to Castration.
Journal ArticleEur Urol Focus, 5 (6), pp. 998-1006, 2019.
Omega-3 fatty acids decrease prostate cancer progression associated with an anti-tumor immune response in eugonadal and castrated mice.
Journal ArticleProstate, 79 (1), pp. 9-20, 2019, ISSN: 0270-4137.
Active projects
- Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
- Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2022-06-13
- En route towards prebiotic clinical trials for enhancement of immunotherapies in bladder and prostate cancers, Subvention, The W. Garfield Weston Foundation, Transformational Research, from 2020-06-01 to 2023-05-31
- Institut sur la nutrition et les aliments fonctionnels (INAF), Subvention, Fonds de recherche du Québec - Nature et technologies, Regroupements stratégiques NT, from 2017-04-01 to 2024-03-31
- Interaction between environment, diet, physical activities, and sexual habits, in the risk of prostate cancer. Validation of biomarkers to personnalize preventive interventions., Subvention, Société de recherche sur le cancer, Compétition GRePEC (SRC/FRSQ/MDEIE), from 2012-10-01 to 2021-12-31
- Nutrition, santé et société (NUTRISS), Subvention, Fonds de recherche du Québec - Santé, Nouveaux Centres et Instituts de recherche - Subventions régulières, from 2019-04-01 to 2024-03-31
- Territorialiser les systèmes alimentaires : une révolution pour la planète et la santé durable, Subvention, Alliance santé Québec (AsQ), from 2020-04-01 to 2021-03-31
Recently finished projects
- (FRSQ 85605) Plateforme méthodologique du CRCEO (statistiques uro-oncologie) , Subvention, Fondation du CHU de Québec, from 2019-05-30 to 2020-05-29
- Détresse et satisfactions face au processus informationnel et décisionnel lors d'un cancer de la prostate localisé, Subvention, Fondation de l'Université Laval, from 2017-02-01 to 2020-03-31
- Impact of microbiota on prostate cancer: from gut to tumor microenvironment., Subvention, Centre hospitalier universitaire de Montréal, from 2018-12-01 to 2019-12-31
- Plateforme méthodologique du Centre de Recherche Clinique et Evaluative en Oncoloie (CRCEO) uro-oncologie, Subvention, Fondation du CHU de Québec, from 2019-03-05 to 2020-03-04
- Prebiotics to enhance immunotherapy response in bladder cancer, Subvention, The W. Garfield Weston Foundation, 2018 Proof-of-Principle Grant Call, from 2019-01-01 to 2020-12-31
- Projet de recherche CaptoMD : Cancer de la prostate, Subvention, Fondation du CHU de Québec, from 2019-03-22 to 2020-03-21
- Rôle du microbiote intestinal dans le cancer de la prostate, Subvention, Université Laval - Soutien à la recherche, from 2018-05-01 to 2019-04-30
- Toward nutritional and epigenomic interventions in prostate cancer prevention and management, Subvention, Instituts de recherche en santé du Canada, Fonctionnement: Subvention de promotion de l’impact - CCREES, from 2017-10-01 to 2020-09-30