Dr. Laforce obtained his PhD in Clinical Neuropsychology in 1998 and worked as an Assistant Professor in Cognitive Neurosciences before completing his studies in Behavioral Neurology in 2011. He performed a Fellowship in frontotemporal dementia under Dr. Bruce Miller at the Memory and Aging Center, University of California San Francisco. He conducted brain imaging studies using FEG-PET and amyloid PET with Dr. Gil Rabinovici (University of California, Berkeley). He has been the co-leader of the Neurology class at the Laval University Faculty of Medicine, since 2012. He is a Clinician and Researcher in the CHU de Québec research center, member of the C5R (Consortium of Canadian Centres for Clinical Cognitive Research), RQRV (Réseau Québécois de Recherche sur le Vieillissement), and CINQ (Consortium d’Imagerie en Neurosciences et santé mentale de Québec). Dr. Laforce obtained several major grants (CIHR, Weston Brain Institute, RMGA), presented at national and international meetings, published over 100 scientific papers in prestigious journals such as Lancet Neurology, Brain, Neurology, Neuroimage, Alzheimer Research and Therapy. He wrote a book on memory as well as book chapters. Dr. Laforce is one of the Principal Investigators in the great international endeavours GENFI (Genetic Frontotemporal Dementia Initiative) and DIAN (Dominantly Inherited Alzheimer Network). He leads several research projects on the development of cognitive tools (www.dcqtest.org et www.quoco.org) and the clinical utility of molecular imaging such as FDG-PET and amyloid PET in the differential diagnosis of atypical dementias.

1401, 18e Rue
Clinique Interdisciplinaire de Mémoire
Québec, Québec
Canada G1J 1Z4
102 entries « 1 of 11 »

Bouchard LO, Wilson MA, Laforce R, Duchesne S

White Matter Damage in the Semantic Variant of Primary Progressive Aphasia.

Journal Article

Can J Neurol Sci, pp. 1-10, 2019, ISSN: 0317-1671.

Abstract | Links:

Montembeault M, Chapleau M, Jarret J, Boukadi M, Laforce R Jr, Wilson MA, Rouleau I, Brambati SM

Differential language network functional connectivity alterations in Alzheimer's disease and the semantic variant of primary progressive aphasia.

Journal Article

Cortex, 117 , pp. 284-298, 2019, ISSN: 0010-9452.

Abstract | Links:

Premi E, Calhoun VD, Diano M, Gazzina S, Cosseddu M, Alberici A, Archetti S, Paternico D, Gasparotti R, van Swieten J, Galimberti D, Sanchez-Valle R, Laforce R Jr, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe J, Vandenberghe R, Finger E, Tagliavini F, de Mendonca A, Santana I, Butler C, Ducharme S, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Cappa S, Sorbi S, Padovani A, Rohrer JD, Borroni B, Genetic FTD Initiative, GENFI

The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint.

Journal Article

Neuroimage, 189 , pp. 645-654, 2019, ISSN: 1053-8119.

Abstract | Links:

Mutsaerts HJMM, Mirza SS, Petr J, Thomas DL, Cash DM, Bocchetta M, de Vita E, Metcalfe AWS, Shirzadi Z, Robertson AD, Tartaglia MC, Mitchell SB, Black SE, Freedman M, Tang-Wai D, Keren R, Rogaeva E, van Swieten J, Laforce R, Tagliavini F, Borroni B, Galimberti D, Rowe JB, Graff C, Frisoni GB, Finger E, Sorbi S, de Mendonca A, Rohrer JD, MacIntosh BJ, Masellis M, GENFI consortium

Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study.

Journal Article

Brain, 142 (4), pp. 1108-1120, 2019, ISSN: 0006-8950.

Abstract | Links:

van der Ende EL, Meeter LH, Stingl C, van Rooij JGJ, Stoop MP, Nijholt DAT, Sanchez-Valle R, Graff C, Oijerstedt L, Grossman M, McMillan C, Pijnenburg YAL, Laforce R Jr, Binetti G, Benussi L, Ghidoni R, Luider TM, Seelaar H, van Swieten JC

Novel CSF biomarkers in genetic frontotemporal dementia identified by proteomics.

Journal Article

Ann Clin Transl Neurol, 6 (4), pp. 698-707, 2019, ISSN: 2328-9503.

Abstract | Links:

Cury C, Durrleman S, Cash DM, Lorenzi M, Nicholas JM, Bocchetta M, van Swieten JC, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni GB, Laforce R Jr, Finger E, de Mendonca A, Sorbi S, Ourselin S, Rohrer JD, Modat M, Genetic FTD Initiative, GENFI

Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: Initial application to the GENFI cohort.

Journal Article

Neuroimage, 188 , pp. 282-290, 2019, ISSN: 1053-8119.

Abstract | Links:

Macoir J, Hudon C, Tremblay MP, Laforce RJ, Wilson MA

The contribution of semantic memory to the recognition of basic emotions and emotional valence: Evidence from the semantic variant of primary progressive aphasia.

Journal Article

Soc Neurosci, pp. 1-12, 2019, ISSN: 1747-0919.

Abstract | Links:

Lavoie M, Bier N, Laforce R Jr, Macoir J

Improvement in functional vocabulary and generalization to conversation following a self-administered treatment using a smart tablet in primary progressive aphasia.

Journal Article

Neuropsychol Rehabil, pp. 1-31, 2019, ISSN: 0960-2011.

Abstract | Links:

Rittman T, Borchert R, Jones S, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Graff C, Tagliavini F, Frisoni GB, Laforce R Jr, Finger E, Mendonca A, Sorbi S, Rohrer JD, Rowe JB, Genetic Frontotemporal Dementia Initiative (GENFI)

Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia.

Journal Article

Neurobiol Aging, 77 , pp. 169-177, 2019, ISSN: 0197-4580.

Abstract | Links:

Laforce R Jr, Soucy JP, Sellami L, Dallaire-Theroux C, Brunet F, Bergeron D, Miller BL, Ossenkoppele R

Molecular imaging in dementia: Past, present, and future.

Journal Article

Alzheimers Dement, 14 (11), pp. 1522-1552, 2018, ISSN: 1552-5260.

Abstract | Links:

102 entries « 1 of 11 »
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Active projects

  • Centre hospitalier universitaire de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre thématique de recherche en neurosciences, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1999-06-01 to 2020-10-18
  • Genetic Frontotemporal dementia Initiative (GENFI), Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-07-01 to 2019-06-30

Recently finished projects

  • Apraxie progressive de la parole : profils clinique, évolution et diagnostique différentiel, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2016-08-20 to 2017-08-19
  • Canadian Consortium on Neurodegeneration in Aging - Full proposal, Subvention, Instituts de recherche en santé du Canada, Consortium canadien en neurodégénérescence et vieillissement (CCNV), from 2014-04-01 to 2019-03-31
  • Étude du métabolisme cérébral chez les porteurs asymptomatiques d'une mutation MAPT : une sous-étude GENFI, Subvention, Société Alzheimer de Québec, from 2017-11-07 to 2018-11-06
  • IUCPQ application for Core Clinical Center for CTSN network, Subvention, National Institute of Health (USA), Centres cliniques principaux pour le Réseau d’essais chirurgicaux cardiothoraciques (CTSN), from 2013-07-17 to 2019-01-31
Data provided by the Université Laval research projects registery