Dr. Laforce obtained his PhD in Clinical Neuropsychology in 1998 and worked as an Assistant Professor in Cognitive Neurosciences before completing his studies in Behavioral Neurology in 2011. He performed a Fellowship in frontotemporal dementia under Dr. Bruce Miller at the Memory and Aging Center, University of California San Francisco. He conducted brain imaging studies using FEG-PET and amyloid PET with Dr. Gil Rabinovici (University of California, Berkeley). He has been the co-leader of the Neurology class at the Laval University Faculty of Medicine, since 2012. He is a Clinician and Researcher in the CHU de Québec research center, member of the C5R (Consortium of Canadian Centres for Clinical Cognitive Research), RQRV (Réseau Québécois de Recherche sur le Vieillissement), and CINQ (Consortium d’Imagerie en Neurosciences et santé mentale de Québec). Dr. Laforce obtained several major grants (CIHR, Weston Brain Institute, RMGA), presented at national and international meetings, published over 100 scientific papers in prestigious journals such as Lancet Neurology, Brain, Neurology, Neuroimage, Alzheimer Research and Therapy. He wrote a book on memory as well as book chapters. Dr. Laforce is one of the Principal Investigators in the great international endeavours GENFI (Genetic Frontotemporal Dementia Initiative) and DIAN (Dominantly Inherited Alzheimer Network). He leads several research projects on the development of cognitive tools (www.dcqtest.org et www.quoco.org) and the clinical utility of molecular imaging such as FDG-PET and amyloid PET in the differential diagnosis of atypical dementias.

1401, 18e Rue
Clinique Interdisciplinaire de Mémoire
9
Québec, Québec
Canada G1J 1Z4
127 entries « 1 of 13 »

Bergeron D, Beauregard JM, Soucy JP, Verret L, Poulin S, Matias-Guiu JA, Cabrera-Martin MN, Bouchard RW, Laforce R

Posterior Cingulate Cortex Hypometabolism in Non-Amnestic Variants of Alzheimer's Disease.

Journal Article

J Alzheimers Dis, 2020, ISSN: 1387-2877.

Abstract | Links:

Tavares TP, Mitchell DGV, Coleman KK, Coleman BL, Shoesmith CL, Butler CR, Santana I, Danek A, Gerhard A, de Mendonca A, Borroni B, Tartaglia MC, Graff C, Galimberti D, Tagliavini F, Moreno F, Frisoni G, Rowe JB, Levin J, Van Swieten JC, Otto M, Synofzik M, Sanchez-Valle R, Vandenberghe R, Laforce RJ, Ghidoni R, Sorbi S, Ducharme S, Masellis M, Rohrer J, Finger E

Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration.

Journal Article

J Neurol Neurosurg Psychiatry, 91 (9), pp. 975-984, 2020, ISSN: 0022-3050.

Abstract | Links:

Convery RS, Bocchetta M, Greaves CV, Moore KM, Cash DM, Van Swieten J, Moreno F, Sanchez-Valle R, Borroni B, Laforce R Jr, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler C, Gerhard A, Levin J, Danek A, Otto M, Warren JD, Rohrer JD, Genetic FTD Initiative (GENFI)

Abnormal pain perception is associated with thalamo-cortico-striatal atrophy in C9orf72 expansion carriers in the GENFI cohort.

Journal Article

J Neurol Neurosurg Psychiatry, 2020, ISSN: 0022-3050.

Abstract | Links:

Lavoie M, Bier N, Laforce R Jr, Macoir J

Improvement in functional vocabulary and generalization to conversation following a self-administered treatment using a smart tablet in primary progressive aphasia.

Journal Article

Neuropsychol Rehabil, 30 (7), pp. 1224-1254, 2020, ISSN: 0960-2011.

Abstract | Links:

Ismail Z, Black SE, Camicioli R, Chertkow H, Herrmann N, Laforce R Jr, Montero-Odasso M, Rockwood K, Rosa-Neto P, Seitz D, Sivananthan S, Smith EE, Soucy JP, Vedel I, Gauthier S, CCCDTD5 participants

Recommendations of the 5th Canadian Consensus Conference on the diagnosis and treatment of dementia.

Journal Article

Alzheimers Dement, 16 (8), pp. 1182-1195, 2020, ISSN: 1552-5260.

Abstract | Links:

Le Blanc G, Jette Pomerleau V, McCarthy J, Borroni B, van Swieten J, Galimberti D, Sanchez-Valle R, LaForce R Jr, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Vandenberghe R, Finger E, Tagliavini F, de Mendonca A, Santana I, Butler C, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Sorbi S, Rohrer JD, Ducharme S, GENetic Frontotemporal dementia Initiative (GENFI)

Faster Cortical Thinning and Surface Area Loss in Presymptomatic and Symptomatic C9orf72 Repeat Expansion Adult Carriers.

Journal Article

Ann Neurol, 88 (1), pp. 113-122, 2020, ISSN: 0364-5134.

Abstract | Links:

Ducharme S, Dols A, Laforce R, Devenney E, Kumfor F, van den Stock J, Dallaire-Theroux C, Seelaar H, Gossink F, Vijverberg E, Huey E, Vandenbulcke M, Masellis M, Trieu C, Onyike C, Caramelli P, de Souza LC, Santillo A, Waldo ML, Landin-Romero R, Piguet O, Kelso W, Eratne D, Velakoulis D, Ikeda M, Perry D, Pressman P, Boeve B, Vandenberghe R, Mendez M, Azuar C, Levy R, Le Ber I, Baez S, Lerner A, Ellayosyula R, Pasquier F, Galimberti D, Scarpini E, van Swieten J, Hornberger M, Rosen H, Hodges J, Diehl-Schmid J, Pijnenburg Y

Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders.

Journal Article

Brain, 143 (6), pp. 1632-1650, 2020, ISSN: 0006-8950.

Abstract | Links:

van der Ende EL, Xiao M, Xu D, Poos JM, Panman JL, Jiskoot LC, Meeter LH, Dopper EG, Papma JM, Heller C, Convery R, Moore K, Bocchetta M, Neason M, Peakman G, Cash DM, Teunissen CE, Graff C, Synofzik M, Moreno F, Finger E, Sanchez-Valle R, Vandenberghe R, Laforce R Jr, Masellis M, Tartaglia MC, Rowe JB, Butler CR, Ducharme S, Gerhard A, Danek A, Levin J, Pijnenburg YA, Otto M, Borroni B, Tagliavini F, de Mendonca A, Santana I, Galimberti D, Seelaar H, Rohrer JD, Worley PF, van Swieten JC, Genetic Frontotemporal Dementia Initiative (GENFI)

Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia.

Journal Article

J Neurol Neurosurg Psychiatry, 91 (6), pp. 612-621, 2020, ISSN: 0022-3050.

Abstract | Links:

Zukotynski K, Gaudet V, Kuo PH, Adamo S, Goubran M, Scott CJM, Bocti C, Borrie M, Chertkow H, Frayne R, Hsiung R, Laforce R Jr, Noseworthy MD, Prato FS, Sahlas DJ, Smith EE, Sossi V, Thiel A, Soucy JP, Tardif JC, Black SE

The Use of Random Forests to Identify Brain Regions on Amyloid and FDG PET Associated With MoCA Score.

Journal Article

Clin Nucl Med, 45 (6), pp. 427-433, 2020, ISSN: 0363-9762.

Abstract | Links:

Beaudin M, Sellami L, Martel C, Touzel-Deschenes L, Houle G, Martineau L, Lacroix K, Lavallee A, Chrestian N, Rouleau GA, Gros-Louis F, Laforce R Jr, Dupre N

Characterization of the phenotype with cognitive impairment and protein mislocalization in SCA34.

Journal Article

Neurol Genet, 6 (2), pp. e403, 2020, ISSN: 2376-7839.

Abstract | Links:

127 entries « 1 of 13 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre thématique de recherche en neurosciences, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1999-06-01 to 2023-05-01
  • Chaire de recherche sur les aphasies primaires progressives, Subvention, Fondation de l'Université Laval, from 2019-07-01 to 2024-06-30
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, Subvention, Instituts de recherche en santé du Canada, Consortium canadien en neurodégénérescence et vieillissement (CCNV), from 2019-04-01 to 2024-03-31
  • Projet de recherche sur le diagnostic différentiel de la variante frontale de la maladie d'Alzheimer et la variante comportementale de la démence frontotemporelle , Subvention, Fondation du CHU de Québec, from 2020-05-07 to 2021-05-06

Recently finished projects

  • Genetic Frontotemporal dementia Initiative (GENFI), Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-07-01 to 2020-06-30
Data provided by the Université Laval research projects registery