Dr. Laforce obtained his PhD in Clinical Neuropsychology in 1998 and worked as an Assistant Professor in Cognitive Neurosciences before completing his studies in Behavioral Neurology in 2011. He performed a Fellowship in frontotemporal dementia under Dr. Bruce Miller at the Memory and Aging Center, University of California San Francisco. He conducted brain imaging studies using FEG-PET and amyloid PET with Dr. Gil Rabinovici (University of California, Berkeley). He has been the co-leader of the Neurology class at the Laval University Faculty of Medicine, since 2012. He is a Clinician and Researcher in the CHU de Québec research center, member of the C5R (Consortium of Canadian Centres for Clinical Cognitive Research), RQRV (Réseau Québécois de Recherche sur le Vieillissement), and CINQ (Consortium d’Imagerie en Neurosciences et santé mentale de Québec). Dr. Laforce obtained several major grants (CIHR, Weston Brain Institute, RMGA), presented at national and international meetings, published over 100 scientific papers in prestigious journals such as Lancet Neurology, Brain, Neurology, Neuroimage, Alzheimer Research and Therapy. He wrote a book on memory as well as book chapters. Dr. Laforce is one of the Principal Investigators in the great international endeavours GENFI (Genetic Frontotemporal Dementia Initiative) and DIAN (Dominantly Inherited Alzheimer Network). He leads several research projects on the development of cognitive tools (www.dcqtest.org et www.quoco.org) and the clinical utility of molecular imaging such as FDG-PET and amyloid PET in the differential diagnosis of atypical dementias.

1401, 18e Rue
Clinique Interdisciplinaire de Mémoire
9
Québec, Québec
Canada G1J 1Z4
123 entries « 1 of 13 »

Le Blanc G, Jette Pomerleau V, McCarthy J, Borroni B, van Swieten J, Galimberti D, Sanchez-Valle R, LaForce R Jr, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Vandenberghe R, Finger E, Tagliavini F, de Mendonca A, Santana I, Butler C, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Sorbi S, Rohrer JD, Ducharme S, GENetic Frontotemporal dementia Initiative (GENFI)

Faster Cortical Thinning and Surface Area Loss in Presymptomatic and Symptomatic C9orf72 Repeat Expansion Adult Carriers.

Journal Article

Ann Neurol, 88 (1), pp. 113-122, 2020, ISSN: 0364-5134.

Abstract | Links:

Ducharme S, Dols A, Laforce R, Devenney E, Kumfor F, van den Stock J, Dallaire-Theroux C, Seelaar H, Gossink F, Vijverberg E, Huey E, Vandenbulcke M, Masellis M, Trieu C, Onyike C, Caramelli P, de Souza LC, Santillo A, Waldo ML, Landin-Romero R, Piguet O, Kelso W, Eratne D, Velakoulis D, Ikeda M, Perry D, Pressman P, Boeve B, Vandenberghe R, Mendez M, Azuar C, Levy R, Le Ber I, Baez S, Lerner A, Ellayosyula R, Pasquier F, Galimberti D, Scarpini E, van Swieten J, Hornberger M, Rosen H, Hodges J, Diehl-Schmid J, Pijnenburg Y

Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders.

Journal Article

Brain, 143 (6), pp. 1632-1650, 2020, ISSN: 0006-8950.

Abstract | Links:

van der Ende EL, Xiao M, Xu D, Poos JM, Panman JL, Jiskoot LC, Meeter LH, Dopper EG, Papma JM, Heller C, Convery R, Moore K, Bocchetta M, Neason M, Peakman G, Cash DM, Teunissen CE, Graff C, Synofzik M, Moreno F, Finger E, Sanchez-Valle R, Vandenberghe R, Laforce R Jr, Masellis M, Tartaglia MC, Rowe JB, Butler CR, Ducharme S, Gerhard A, Danek A, Levin J, Pijnenburg YA, Otto M, Borroni B, Tagliavini F, de Mendonca A, Santana I, Galimberti D, Seelaar H, Rohrer JD, Worley PF, van Swieten JC, Genetic Frontotemporal Dementia Initiative (GENFI)

Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia.

Journal Article

J Neurol Neurosurg Psychiatry, 91 (6), pp. 612-621, 2020, ISSN: 0022-3050.

Abstract | Links:

Zukotynski K, Gaudet V, Kuo PH, Adamo S, Goubran M, Scott CJM, Bocti C, Borrie M, Chertkow H, Frayne R, Hsiung R, Laforce R Jr, Noseworthy MD, Prato FS, Sahlas DJ, Smith EE, Sossi V, Thiel A, Soucy JP, Tardif JC, Black SE

The Use of Random Forests to Identify Brain Regions on Amyloid and FDG PET Associated With MoCA Score.

Journal Article

Clin Nucl Med, 45 (6), pp. 427-433, 2020, ISSN: 0363-9762.

Abstract | Links:

Beaudin M, Sellami L, Martel C, Touzel-Deschenes L, Houle G, Martineau L, Lacroix K, Lavallee A, Chrestian N, Rouleau GA, Gros-Louis F, Laforce R Jr, Dupre N

Characterization of the phenotype with cognitive impairment and protein mislocalization in SCA34.

Journal Article

Neurol Genet, 6 (2), pp. e403, 2020, ISSN: 2376-7839.

Abstract | Links:

Heller C, Foiani MS, Moore K, Convery R, Bocchetta M, Neason M, Cash DM, Thomas D, Greaves CV, Woollacott IO, Shafei R, Van Swieten JC, Moreno F, Sanchez-Valle R, Borroni B, Laforce R Jr, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Frisoni G, Sorbi S, Otto M, Heslegrave AJ, Zetterberg H, Rohrer JD, GENFI

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.

Journal Article

J Neurol Neurosurg Psychiatry, 91 (3), pp. 263-270, 2020, ISSN: 0022-3050.

Abstract | Links:

Auclair-Ouellet N, Fossard M, Macoir J, Laforce R Jr

The Nonverbal Processing of Actions Is an Area of Relative Strength in the Semantic Variant of Primary Progressive Aphasia.

Journal Article

J Speech Lang Hear Res, 63 (2), pp. 569-584, 2020, ISSN: 1092-4388.

Abstract | Links:

Moore K, Convery R, Bocchetta M, Neason M, Cash DM, Greaves C, Russell LL, Clarke MTM, Peakman G, van Swieten J, Jiskoot L, Moreno F, Barandiaran M, Sanchez-Valle R, Borroni B, Laforce R Jr, Dore MC, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Karnath HO, Vandenberghe R, de Mendonca A, Maruta C, Tagliavini F, Santana I, Ducharme S, Butler C, Gerhard A, Levin J, Danek A, Otto M, Warren JD, Rohrer JD, Genetic FTD Initiative, GENFI.

A modified Camel and Cactus Test detects presymptomatic semantic impairment in genetic frontotemporal dementia within the GENFI cohort.

Journal Article

Appl Neuropsychol Adult, pp. 1-8, 2020, ISSN: 2327-9095.

Abstract | Links:

Moore KM, Nicholas J, Grossman M, McMillan CT, Irwin DJ, Massimo L, Van Deerlin VM, Warren JD, Fox NC, Rossor MN, Mead S, Bocchetta M, Boeve BF, Knopman DS, Graff-Radford NR, Forsberg LK, Rademakers R, Wszolek ZK, van Swieten JC, Jiskoot LC, Meeter LH, Dopper EG, Papma JM, Snowden JS, Saxon J, Jones M, Pickering-Brown S, Le Ber I, Camuzat A, Brice A, Caroppo P, Ghidoni R, Pievani M, Benussi L, Binetti G, Dickerson BC, Lucente D, Krivensky S, Graff C, Oijerstedt L, Fallstrom M, Thonberg H, Ghoshal N, Morris JC, Borroni B, Benussi A, Padovani A, Galimberti D, Scarpini E, Fumagalli GG, Mackenzie IR, Hsiung GR, Sengdy P, Boxer AL, Rosen H, Taylor JB, Synofzik M, Wilke C, Sulzer P, Hodges JR, Halliday G, Kwok J, Sanchez-Valle R, Llado A, Borrego-Ecija S, Santana I, Almeida MR, Tabuas-Pereira M, Moreno F, Barandiaran M, Indakoetxea B, Levin J, Danek A, Rowe JB, Cope TE, Otto M, Anderl-Straub S, de Mendonca A, Maruta C, Masellis M, Black SE, Couratier P, Lautrette G, Huey ED, Sorbi S, Nacmias B, Laforce R Jr, Tremblay ML, Vandenberghe R, Damme PV, Rogalski EJ, Weintraub S, Gerhard A, Onyike CU, Ducharme S, Papageorgiou SG, Lyn AS, Brodtmann A, Finger E, Guerreiro R, Bras J, Rohrer JD, FTD Prevention Initiative

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.

Journal Article

Lancet Neurol, 19 (2), pp. 145-156, 2020, ISSN: 1474-4422.

Abstract | Links:

Macoir J, Laforce R, Wilson MA, Tremblay MP, Hudon C

The role of semantic memory in the recognition of emotional valence conveyed by written words.

Journal Article

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn, 27 (2), pp. 270-288, 2020, ISSN: 1382-5585.

Abstract | Links:

123 entries « 1 of 13 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre thématique de recherche en neurosciences, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1999-06-01 to 2023-05-01
  • Chaire de recherche sur les aphasies primaires progressives, Subvention, Fondation de l'Université Laval, from 2019-07-01 to 2024-06-30
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, Subvention, Instituts de recherche en santé du Canada, Consortium canadien en neurodégénérescence et vieillissement (CCNV), from 2019-04-01 to 2024-03-31

Recently finished projects

  • Genetic Frontotemporal dementia Initiative (GENFI), Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-07-01 to 2019-06-30
Data provided by the Université Laval research projects registery