Dr. Laforce obtained his PhD in Clinical Neuropsychology in 1998 and worked as an Assistant Professor in Cognitive Neurosciences before completing his studies in Behavioral Neurology in 2011. He performed a Fellowship in frontotemporal dementia under Dr. Bruce Miller at the Memory and Aging Center, University of California San Francisco. He conducted brain imaging studies using FEG-PET and amyloid PET with Dr. Gil Rabinovici (University of California, Berkeley). He has been the co-leader of the Neurology class at the Laval University Faculty of Medicine, since 2012. He is a Clinician and Researcher in the CHU de Québec research center, member of the C5R (Consortium of Canadian Centres for Clinical Cognitive Research), RQRV (Réseau Québécois de Recherche sur le Vieillissement), and CINQ (Consortium d’Imagerie en Neurosciences et santé mentale de Québec). Dr. Laforce obtained several major grants (CIHR, Weston Brain Institute, RMGA), presented at national and international meetings, published over 100 scientific papers in prestigious journals such as Lancet Neurology, Brain, Neurology, Neuroimage, Alzheimer Research and Therapy. He wrote a book on memory as well as book chapters. Dr. Laforce is one of the Principal Investigators in the great international endeavours GENFI (Genetic Frontotemporal Dementia Initiative) and DIAN (Dominantly Inherited Alzheimer Network). He leads several research projects on the development of cognitive tools (www.dcqtest.org et www.quoco.org) and the clinical utility of molecular imaging such as FDG-PET and amyloid PET in the differential diagnosis of atypical dementias.

1401, 18e Rue
Clinique Interdisciplinaire de Mémoire
Québec, Québec
Canada G1J 1Z4
92 entries « 1 of 19 »

Young AL, Marinescu RV, Oxtoby NP, Bocchetta M, Yong K, Firth NC, Cash DM, Thomas DL, Dick KM, Cardoso J, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni GB, Laforce R Jr, Finger E, de Mendonca A, Sorbi S, Warren JD, Crutch S, Fox NC, Ourselin S, Schott JM, Rohrer JD, Alexander DC, Genetic FTD Initiative (GENFI), Alzheimer's Disease Neuroimaging Initiative (ADNI)

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.

Journal Article

Nat Commun, 9 (1), pp. 4273, 2018, ISSN: 2041-1723.

Abstract | Links:

Jiskoot LC, Bocchetta M, Nicholas JM, Cash DM, Thomas D, Modat M, Ourselin S, Rombouts SARB, Dopper EGP, Meeter LH, Panman JL, van Minkelen R, van der Ende EL, Donker Kaat L, Pijnenburg YAL, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe J, Graff C, Tagliavini F, Frisoni GB, Laforce R Jr, Finger E, de Mendonca A, Sorbi S, Genetic Frontotemporal dementia Initiative (GENFI), Papma JM, van Swieten JC, Rohrer JD

Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study.

Journal Article

Ann Clin Transl Neurol, 5 (9), pp. 1025-1036, 2018, ISSN: 2328-9503.

Abstract | Links:

Schneider R, McKeever P, Kim T, Graff C, van Swieten JC, Karydas A, Boxer A, Rosen H, Miller BL, Laforce R Jr, Galimberti D, Masellis M, Borroni B, Zhang Z, Zinman L, Rohrer JD, Tartaglia MC, Robertson J, Genetic FTD Initiative (GENFI)

Downregulation of exosomal miR-204-5p and miR-632 as a biomarker for FTD: a GENFI study.

Journal Article

J Neurol Neurosurg Psychiatry, 89 (8), pp. 851-858, 2018, ISSN: 0022-3050.

Abstract | Links:

Hsu S, Gordon BA, Hornbeck R, Norton JB, Levitch D, Louden A, Ziegemeier E, Laforce R Jr, Chhatwal J, Day GS, McDade E, Morris JC, Fagan AM, Benzinger TLS, Goate AM, Cruchaga C, Bateman RJ, Dominantly Inherited Alzheimer Network (DIAN), Karch CM

Discovery and validation of autosomal dominant Alzheimer's disease mutations.

Journal Article

Alzheimers Res Ther, 10 (1), pp. 67, 2018.

Abstract | Links:

Laforce R Jr, Soucy JP, Sellami L, Dallaire-Theroux C, Brunet F, Bergeron D, Miller BL, Ossenkoppele R

Molecular imaging in dementia: Past, present, and future.

Journal Article

Alzheimers Dement, 2018, ISSN: 1552-5260.

Abstract | Links:

92 entries « 1 of 19 »

Active projects

  • Canadian Consortium on Neurodegeneration in Aging - Full proposal, Subvention, Instituts de recherche en santé du Canada, Consortium canadien en neurodégénérescence et vieillissement (CCNV), from 2014-04-01 to 2019-03-31
  • Centre hospitalier universitaire de Québec - CHU de Québec-Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre thématique de recherche en neurosciences, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1999-06-01 to 2020-10-18
  • Genetic Frontotemporal dementia Initiative (GENFI), Subvention, Sunnybrook Research Institute, from 2015-09-23 to 2019-09-22
  • IUCPQ application for Core Clinical Center for CTSN network, Subvention, National Institute of Health (USA), Centres cliniques principaux pour le Réseau d’essais chirurgicaux cardiothoraciques (CTSN), from 2013-07-17 to 2019-01-31

Recently finished projects

  • Apraxie progressive de la parole : profils clinique, évolution et diagnostique différentiel, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2016-08-20 to 2017-08-19
  • Cognitive profile of the Alzheimer's disease on the Dépistage Cognitif de Québec, Subvention, Société Alzheimer de Québec, from 2016-02-01 to 2017-03-31
  • Le dépistage des démences atypiques., Subvention, Centre d'intégration de la recherche et des technologies sur les maladies cognitives, from 2015-01-22 to 2017-01-21
Data provided by the Université Laval research projects registery