Dr. Laforce obtained his PhD in Clinical Neuropsychology in 1998 and worked as an Assistant Professor in Cognitive Neurosciences before completing his studies in Behavioral Neurology in 2011. He performed a short Fellowship in frontotemporal dementia under Dr. Bruce Miller at the Memory and Aging Center, University of California San Francisco. He conducted brain imaging studies using FDG-PET and amyloid PET with Dr. Gil Rabinovici (University of California, Berkeley). He was co-leader of the Neurology class at Laval University for 5 years. He is a Clinician and Researcher in CHU de Québec Research Center, member of the C5R (Consortium of Canadian Centres for Clinical Cognitive Research) and RQRV (Réseau Québécois de Recherche sur le Vieillissement). Dr. Laforce obtained several major grants (CIHR, Weston Brain Institute), presented at national and international meetings, published over 100 scientific papers in prestigious journals such as Lancet Neurology, Brain, Neurology. He wrote a book on memory as well as several book chapters. Dr. Laforce is one of the PIs in the great international endeavour GENFI (Genetic Frontotemporal Dementia Initiative) and DIAN (Dominantly Inherited Alzheimer Network). He leads several research projects on the development of cognitive tools (www.dcqtest.org et www.quoco.org) and the clinical utility of molecular imaging such as FDG-PET and amyloid PET in the differential diagnosis of atypical dementias. He holds the Chaire de Recherche sur les Aphasies Primaires Progressives – Fondation Famille Lemaire (https://app-ffl.ulaval.ca/).

1401, 18e Rue
Clinique Interdisciplinaire de Mémoire
S-0033
Québec, Québec
Canada G1J 1Z4
136 entries « 1 of 14 »

Benussi A, Premi E, Gazzina S, Brattini C, Bonomi E, Alberici A, Jiskoot L, van Swieten JC, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Masellis M, Tartaglia C, Rowe JB, Finger E, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Frisoni G, Ghidoni R, Sorbi S, Le Ber I, Pasquier F, Peakman G, Todd E, Bocchetta M, Rohrer JD, Borroni B, Genetic FTD Initiative (GENFI)

Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal Dementia.

Journal Article

JAMA Netw Open, 4 (1), pp. e2030194, 2021, ISSN: 2574-3805.

Abstract | Links:

Malpetti M, Jones PS, Tsvetanov KA, Rittman T, van Swieten JC, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Frisoni GB, Ghidoni R, Sorbi S, Heller C, Todd EG, Bocchetta M, Cash DM, Convery RS, Peakman G, Moore KM, Rohrer JD, Kievit RA, Rowe JB, Genfi OBOTGFI

Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes.

Journal Article

Alzheimers Dement, 2020, ISSN: 1552-5260.

Abstract | Links:

Convery RS, Bocchetta M, Greaves CV, Moore KM, Cash DM, Van Swieten J, Moreno F, Sanchez-Valle R, Borroni B, Laforce R Jr, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler C, Gerhard A, Levin J, Danek A, Otto M, Warren JD, Rohrer JD, Genetic FTD Initiative (GENFI)

Abnormal pain perception is associated with thalamo-cortico-striatal atrophy in C9orf72 expansion carriers in the GENFI cohort.

Journal Article

J Neurol Neurosurg Psychiatry, 91 (12), pp. 1325-1328, 2020, ISSN: 0022-3050.

Abstract | Links:

Russell LL, Greaves CV, Bocchetta M, Nicholas J, Convery RS, Moore K, Cash DM, van Swieten J, Jiskoot L, Moreno F, Sanchez-Valle R, Borroni B, Laforce R Jr, Masellis M, Tartaglia MC, Graff C, Rotondo E, Galimberti D, Rowe JB, Finger E, Synofzik M, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler C, Gerhard A, Levin J, Danek A, Otto M, Warren JD, Rohrer JD, Genetic FTD Initiative, GENFI

Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort.

Journal Article

Cortex, 133 , pp. 384-398, 2020, ISSN: 0010-9452.

Abstract | Links:

Gravel A, Hudon C, Meilleur-Durand S, Sellami L, Bergeron D, Paradis A, Verret L, Fortin MP, Poulin S, Macoir J, Bouchard RW, Laforce R Jr

Validation of the Dépistage Cognitif de Québec in the Oldest Old.

Journal Article

Can Geriatr J, 23 (4), pp. 283-288, 2020, ISSN: 1925-8348.

Abstract | Links:

Tsvetanov KA, Gazzina S, Jones PS, van Swieten J, Borroni B, Sanchez-Valle R, Moreno F, Laforce R Jr, Graff C, Synofzik M, Galimberti D, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler C, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Ghidoni R, Sorbi S, Rohrer JD, Rowe JB, Genetic FTD Initiative, GENFI

Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia.

Journal Article

Alzheimers Dement, 2020, ISSN: 1552-5260.

Abstract | Links:

Bergeron D, Sellami L, Poulin S, Verret L, Bouchard RW, Laforce R Jr

The Behavioral/Dysexecutive Variant of Alzheimer's Disease: A Case Series with Clinical, Neuropsychological, and FDG-PET Characterization.

Journal Article

Dement Geriatr Cogn Disord, pp. 1-8, 2020, ISSN: 1420-8008.

Abstract | Links:

Montreuil S, Poulin E, Bergeron D, Sellami L, Verret L, Fortin MP, Poulin S, Macoir J, Hudon C, Bouchard RW, Lavoie M, Laforce R

Cognitive Profile of the Logopenic Variant of Primary Progressive Aphasia Using the Dépistage Cognitif de Québec.

Journal Article

Dement Geriatr Cogn Disord, pp. 1-8, 2020, ISSN: 1420-8008.

Abstract | Links:

Lavoie M, Bier N, Laforce R Jr, Macoir J

Improvement in functional vocabulary and generalization to conversation following a self-administered treatment using a smart tablet in primary progressive aphasia.

Journal Article

Neuropsychol Rehabil, 30 (7), pp. 1224-1254, 2020, ISSN: 0960-2011.

Abstract | Links:

Altmann A, Cash DM, Bocchetta M, Heller C, Reynolds R, Moore K, Convery RS, Thomas DL, van Swieten JC, Moreno F, Sanchez-Valle R, Borroni B, Laforce R Jr, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Frisoni G, Ghidoni R, Sorbi S, Otto M, Ryten M, Rohrer JD, Genetic FTD Initiative, GENFI

Analysis of brain atrophy and local gene expression in genetic frontotemporal dementia.

Journal Article

Brain Commun, 2 (2), 2020, ISSN: 2632-1297.

Abstract | Links:

136 entries « 1 of 14 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre thématique de recherche en neurosciences, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1999-06-01 to 2023-05-01
  • Chaire de recherche sur les aphasies primaires progressives, Subvention, Fondation de l'Université Laval, from 2019-07-01 to 2024-06-30
  • Phase Two of the Canadian Consortium on Neurodegeneration in Aging, Subvention, Instituts de recherche en santé du Canada, Consortium canadien en neurodégénérescence et vieillissement (CCNV), from 2019-04-01 to 2024-03-31
  • Projet de recherche sur le diagnostic différentiel de la variante frontale de la maladie d'Alzheimer et la variante comportementale de la démence frontotemporelle , Subvention, Fondation du CHU de Québec, from 2020-05-07 to 2021-05-06

Recently finished projects

  • Genetic Frontotemporal dementia Initiative (GENFI), Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-07-01 to 2020-06-30
Data provided by the Université Laval research projects registery