Philippe Després is an Associate Professor in the Department of Physics, Engineering Physics and Optics and member of the Cancer Research Center of Université Laval, as well as a Medical Physicist at CHU de Québec and a regular researcher at its affiliated Research Center. He was trained at Université Laval (MSc 2000, Physics), Université de Montréal (PhD 2005, Physics) and University of California, San Francisco (postdoc 2005-2007, Biomedical Engineering, Molecular Imaging). He is involved in several projects encompassing hardware and software aspects of medical imaging modalities, notably low-dose X-ray imaging, advanced imaging techniques, and solid-state detectors for molecular imaging. He pioneered high-performance computing (HPC) approaches with commodity graphics hardware (GPUs) that led to innovative applications in image processing/reconstruction and radiation dose calculations, including a fast GPU-based Monte Carlo engine to simulate energy transport in matter (GPUMCD). As a HPC expert, he is also involved in data-driven research approaches, data infrastructures and FAIR-compliant research data management. In this regard, he is the Chief Data Officer at CHU de Québec – Université Laval Research Center, the Data Architect of the PULSAR health research platform, the Assistant Director of the Big Data Research Center at Université Laval, and the co-lead of the Sustainable Health axis of the Observatoire international sur les impacts sociétaux de l’IA et du numérique.


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Carignan D, Lessard T, Villeneuve L, Desjardins S, Magnan S, Despres P, Martin AG, Foster W, Guillemette C, Levesque E, Vigneault E

DNA repair gene polymorphisms, tumor control, and treatment toxicity in prostate cancer patients treated with permanent implant prostate brachytherapy.

Journal Article

Prostate, 80 (8), pp. 632-639, 2020, ISSN: 0270-4137.

Abstract | Links:

Frezza A, Joachim-Paquet C, Chauvin M, Despres P

Validation of irtGPUMCD, a GPU-based Monte Carlo internal dosimetry framework for radionuclide therapy.

Journal Article

Phys Med, 73 , pp. 95-104, 2020, ISSN: 1120-1797.

Abstract | Links:

Frezza A, Desport C, Uribe C, Zhao W, Celler A, Despres P, Beauregard JM

Comprehensive SPECT/CT system characterization and calibration for 177Lu quantitative SPECT (QSPECT) with dead-time correction.

Journal Article

EJNMMI Phys, 7 (1), pp. 10, 2020, ISSN: 2197-7364.

Abstract | Links:

Hathout L, Mahmoud O, Wang Y, Vergalasova I, Barkati M, Despres P, Martin AG, Foster W, Lacroix F, Delouya G, Taussky D, Morton G, Vigneault E

A Phase 2 Randomized Pilot Study Comparing High-Dose-Rate Brachytherapy and Low-Dose-Rate Brachytherapy as Monotherapy in Localized Prostate Cancer.

Journal Article

Adv Radiat Oncol, 4 (4), pp. 631-640, 2019, ISSN: 2452-1094.

Abstract | Links:

Belanger C, Cui S, Ma Y, Despres P, Cunha A, Beaulieu L

A GPU-based multi-criteria optimization algorithm for HDR brachytherapy.

Journal Article

Phys Med Biol, 64 (10), pp. 105005, 2019, ISSN: 0031-9155.

Abstract | Links:

Maneval D, Ozell B, Despres P

pGPUMCD: an efficient GPU-based Monte Carlo code for accurate proton dose calculations.

Journal Article

Phys Med Biol, 64 (8), pp. 085018, 2019, ISSN: 0031-9155.

Abstract | Links:

Matenine D, Schmittbuhl M, Bedwani S, Despres P, de Guise JA

Iterative reconstruction for image enhancement and dose reduction in diagnostic cone beam CT imaging.

Journal Article

J Xray Sci Technol, 27 (5), pp. 805-819, 2019, ISSN: 0895-3996.

Abstract | Links:

Cui S, Despres P, Beaulieu L

A multi-criteria optimization approach for HDR prostate brachytherapy: I. Pareto surface approximation.

Journal Article

Phys Med Biol, 63 (20), pp. 205004, 2018, ISSN: 0031-9155.

Abstract | Links:

Cui S, Despres P, Beaulieu L

A multi-criteria optimization approach for HDR prostate brachytherapy: II. Benchmark against clinical plans.

Journal Article

Phys Med Biol, 63 (20), pp. 205005, 2018, ISSN: 0031-9155.

Abstract | Links:

Vigneault E, Martell K, Taussky D, Husain S, Delouya G, Mbodji K, Piotte J, Magnan S, Despres P, Lavallee MC, Aubin S, Beaulieu L, Foster W, Martin AG

Does Seed Migration Increase the Risk of Second Malignancies in Prostate Cancer Patients Treated With Iodine-125 Loose Seeds Brachytherapy?

Journal Article

Int J Radiat Oncol Biol Phys, 100 (5), pp. 1190-1194, 2018, ISSN: 0360-3016.

Abstract | Links:

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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche en données massives, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 2016-06-07 to 2021-06-06
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
  • High-Performance Computing in Medical Physics, Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2018-04-01 to 2023-03-31
  • Major Resource Support for the Particle Physics Group at Université de Montréal, Subvention, Conseil de recherches en sciences naturelles et génie Canada, Programme d'appui aux ressources majeures (ARM), from 2018-04-01 to 2021-03-31
  • NSERC CREATE in Responsible Health and Healthcare Data Science, Subvention, Conseil de recherches en sciences naturelles et génie Canada, Programme de formation orientée vers la nouveauté, la collaboration et l'expérience en recherche (FONCER), from 2019-09-01 to 2025-08-31
  • Optimiser les soins des patients atteints du cancer de la prostate résistant à la castration en utilisant une stratégie de triple traceur en imagerie moléculaire et en radiothérapie ciblée, Subvention, Fonds de recherche du Québec - Santé, ONCOPOLE EMC2: Équipes multi-institutionnelles contre le cancer, from 2018-04-01 to 2021-03-31
  • Prédire l'évolution de l'hépatite C par la fédération de données et l'intelligence artificielle : enjeux éthiques, juridiques, sociaux et de vie privée, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2022-03-31

Recently finished projects

  • 2.4 A better understanding of light-matter interaction: bridging the gap between micro and macro scales, and develong new devices and approaches for the North, Subvention, Secrétariat des programmes interorganismes à l’intention des établissements, Fonds d'excellence en recherche Apogée Canada, from 2016-04-01 to 2020-03-31
  • Artificial INTELLIGENce for efficient community based primary healTh CARE (INTELLIGENT-CARE), Subvention, Instituts de recherche en santé du Canada, Subvention de planification et dissémination, from 2018-02-01 to 2019-03-31
  • L'imagerie moléculaire quantitative au service de la médecine personnalisée, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2016-07-01 to 2019-06-30
  • NSREC CREATE : Medical Physic Research Training Network (MPRTN), Subvention, Conseil de recherches en sciences naturelles et génie Canada, Programme de formation orientée vers la nouveauté, la collaboration et l'expérience en recherche (FONCER), from 2013-04-01 to 2019-03-31
  • Reconstructions tomographiques avancées et imagerie multi-spectrale en tomodensitométrie : vers une caractérisaiton physico-chimique bonifiée des matériaux en sciences de la Terre et de l'environnement, Subvention, Fonds de recherche du Québec - Nature et technologies, Projet de recherche en équipe, from 2017-04-01 to 2020-03-31
Data provided by the Université Laval research projects registery