Dr. Paul R. Fortin, MD, MPH, FRCPC holds the Tier 1 Canada Research Chair in Systemic Autoimmune Rheumatic Diseases, is Professor at Laval University, and Clinical Investigator at the CHU Research Center of Quebec – Laval University. He obtained his medical degree from Laval University and is a graduate of McGill University in rheumatology. He then obtained a Master’s in Public Health from Harvard University’s School of Public Health.

Dr. Fortin is working to better understand the bio-psycho-social impact of systemic autoimmune rheumatic diseases (SARD), such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis, inflammatory myositis, and antiphospholipid syndrome (APS). He is particularly interested in the development of interventions for the treatment of SLE, RA, and APS.

His methodological interests are the development and validation of diagnostic and prognostic tests, new treatments, and new ways to measure the impact of these treatments on the health status of the patient, and on the levels of activity or harm of the disease within SARDs. His other methodological interests include developing healthy lifestyle habits for people with SARD, and measuring the impact of patient knowledge.

Since 2011, Dr. Fortin has been working on the creation and establishment of a new computerized database and biobank that enables the collection of informative biospecimens and clinical data relevant to the study of SARDs. This biobank and database now has more than 13,000 biospecimens, from over 250 people, and has already contributed to translational and clinical research projects, as well as two projects funded by the Canadian Institutes of Health Research.

Dr. Fortin received the Canadian Rheumatology Association (CRA) Young Investigator Award in 1999, the Kirkland Scholar Award in 2008, and the prestigious Research Achievement Award from The Arthritis Society of Canada (2007- 2012). In 2010, he received the Lupus Ontario Hope Award for his outstanding leadership in improving the lives of people with lupus. In May 2015, he received the Jeffrey Shiroky Research Award for his clinical research achievements in rheumatology.

CHUL
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Wirestam L, Enocsson H, Skogh T, Padyukov L, Jonsen A, Urowitz MB, Gladman DD, Romero-Diaz J, Bae SC, Fortin PR, Sanchez-Guerrero J, Clarke AE, Bernatsky S, Gordon C, Hanly JG, Wallace D, Isenberg DA, Rahman A, Merrill J, Ginzler E, Alarcon GS, Chatham WW, Petri M, Khamashta M, Aranow C, Mackay M, Dooley MA, Manzi S, Ramsey-Goldman R, Nived O, Steinsson K, Zoma A, Ruiz-Irastorza G, Lim S, Kalunian K, Inanc M, Vollenhoven RV, Ramos-Casals M, Kamen DL, Jacobsen S, Peschken C, Askanase A, Stoll T, Bruce IN, Wettero J, Sjowall C

Osteopontin and Disease Activity in Patients with Recent-onset Systemic Lupus Erythematosus: Results from the SLICC Inception Cohort.

Journal Article

J Rheumatol, 46 (5), pp. 492-500, 2019, ISSN: 0315-162X.

Abstract | Links:

Lee J, Pineau CA, Da Costa D, Clarke AE, Fortin PR, Neville C, Neville A, Bernatsky S

Response to Middleton KR et als. Yoga and SLE.

Journal Article

Complement Ther Med, 43 , pp. 311, 2019, ISSN: 0965-2299.

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Becker Y, Marcoux G, Allaeys I, Julien AS, Loignon RC, Benk-Fortin H, Rollet-Labelle E, Rauch J, Fortin PR, Boilard E

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA.

Journal Article

Front Immunol, 10 , pp. 1026, 2019, ISSN: 1664-3224.

Abstract | Links:

Radin M, Sciascia S, Erkan D, Pengo V, Tektonidou MG, Ugarte A, Meroni P, Ji L, Belmont HM, Cohen H, Ramires de Jesus G, Branch DW, Fortin PR, Andreoli L, Petri M, Rodriguez E, Rodriguez-Pinto I, Knight JS, Atsumi T, Willis R, Gonzalez E, Lopez-Pedrera R, Rossi Gandara AP, Borges Gualhardo Vendramini M, Banzato A, Sevim E, Barbhaiya M, Efthymiou M, Mackie I, Bertolaccini ML, Andrade D, APS ACTION

The adjusted global antiphospholipid syndrome score (aGAPSS) and the risk of recurrent thrombosis: Results from the APS ACTION cohort.

Journal Article

Semin Arthritis Rheum, 49 (3), pp. 464-468, 2019, ISSN: 0049-0172.

Abstract | Links:

Efthymiou M, Mackie IJ, Lane PJ, Andrade D, Willis R, Erkan D, Sciascia S, Krillis S, Bison E, Borges Galhardo Vendramini M, Romay-Penabad Z, Qi M, Tektonidou M, Ugarte A, Chighizola C, Belmont HM, Aguirre MA, Ji L, Branch DW, de Jesus G, Fortin PR, Andreoli L, Petri M, Cervera R, Rodriguez E, Knight JS, Atsumi T, Vega J, Ecem S, Bertolaccini ML, Pengo V, Cohen H, APS ACTION

Comparison of real world and core laboratory lupus anticoagulant results from the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) clinical database and repository.

Journal Article

J Thromb Haemost, 17 (12), pp. 2069-2080, 2019, ISSN: 1538-7933.

Abstract | Links:

Cesaro A, Defrene J, Lachhab A, Page N, Tardif MR, Al-Shami A, Oravecz T, Fortin PR, Daudelin JF, Labrecque N, Aoudjit F, Pelletier M, Tessier PA

Enhanced myelopoiesis and aggravated arthritis in S100a8-deficient mice.

Journal Article

PLoS ONE, 14 (8), pp. e0221528, 2019.

Abstract | Links:

Dougherty DH, Kwakkenbos L, Carrier ME, Salazar G, Assassi S, Baron M, Bartlett SJ, Furst DE, Gottesman K, van den Hoogen F, Malcarne VL, Mouthon L, Nielson WR, Poiraudeau S, Sauve M, Boire G, Bruns A, Chung L, Denton C, Dunne JV, Fortin P, Frech T, Gill A, Gordon J, Herrick AL, Hinchcliff M, Hudson M, Johnson SR, Jones N, Kafaja S, Larche M, Manning J, Pope J, Spiera R, Steen V, Sutton E, Thorne C, Wilcox P, Thombs BD, Mayes MD, SPIN Investigators

The Scleroderma Patient-Centered Intervention Network Cohort: baseline clinical features and comparison with other large scleroderma cohorts.

Journal Article

Rheumatology (Oxford), 57 (9), pp. 1623-1631, 2018, ISSN: 1462-0324.

Abstract | Links:

Little J, Parker B, Lunt M, Hanly JG, Urowitz MB, Clarke AE, Romero-Diaz J, Gordon C, Bae SC, Bernatsky S, Wallace DJ, Merrill JT, Buyon J, Isenberg DA, Rahman A, Ginzler EM, Petri M, Dooley MA, Fortin P, Gladman DD, Steinsson K, Ramsey-Goldman R, Khamashta MA, Aranow C, Mackay M, Alarcon GS, Manzi S, Nived O, Jonsen A, Zoma AA, van Vollenhoven RF, Ramos-Casals M, Ruiz-Irastorza G, Sam Lim S, Kalunian KC, Inanc M, Kamen DL, Peschken CA, Jacobsen S, Askanase A, Sanchez-Guerrero J, Bruce IN

Glucocorticoid use and factors associated with variability in this use in the Systemic Lupus International Collaborating Clinics Inception Cohort.

Journal Article

Rheumatology (Oxford), 57 (4), pp. 677-687, 2018, ISSN: 1462-0324.

Abstract | Links:

Linge P, Fortin PR, Lood C, Bengtsson AA, Boilard E

The non-haemostatic role of platelets in systemic lupus erythematosus.

Journal Article

Nat Rev Rheumatol, 14 (4), pp. 195-213, 2018.

Abstract | Links:

Merz EL, Kwakkenbos L, Carrier ME, Gholizadeh S, Mills SD, Fox RS, Jewett LR, Williamson H, Harcourt D, Assassi S, Furst DE, Gottesman K, Mayes MD, Moss TP, Thombs BD, Malcarne VL, SPIN Investigators

Factor structure and convergent validity of the Derriford Appearance Scale-24 using standard scoring versus treating 'not applicable' responses as missing data: a Scleroderma Patient-centered Intervention Network (SPIN) cohort study.

Journal Article

BMJ Open, 8 (3), pp. e018641, 2018.

Abstract | Links:

318 entries « 3 of 32 »
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Active projects

  • Canada research chair in Innovate Systemic Autoimmune Rheumatic Disease, Subvention, Secrétariat des programmes interorganismes à l’intention des établissements, Chaires de recherche du Canada - Fonctionnement, from 2019-07-01 to 2026-06-30
  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Hydroxychloroquine in systemic lupus, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2018-04-01 to 2023-03-31
  • Mapping anti-mitochondrial antibodies in systemic lupus erythematosus, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2022-03-31
  • New statistical methods for cohort studies of adverse effects of medications, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2016-07-01 to 2021-06-30
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2020-04-01 to 2025-03-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, Subvention, La société d'arthrite, from 2020-01-01 to 2022-12-31
  • Projet de recherche sur les maladies arthritiques, Subvention, Fondation de l'Université Laval, from 2019-12-01 to 2021-11-30
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2015-07-01 to 2021-06-30
  • The impact of antimalarial drugs in arthritis patients exposed to SARS-CoV-2- the CoVIRAL project, Subvention, La société d'arthrite, from 2020-04-01 to 2023-03-31
  • Unité support du Québec: Un soutien pour la recherche axée sur le patient., Subvention, Instituts de recherche en santé du Canada, Unités de soutien de la stratégie de recherche axée sur le patient(SRAP), from 2014-04-01 to 2022-03-31

Recently finished projects

  • Canadian Network for Advanced interdisciplinary Methods for Prospective Studies of Drug Safety and Effectiveness., Subvention, Instituts de recherche en santé du Canada, Subvention d'équipe : Centre de collaboration pour les études prospectives du RIEM, from 2014-09-01 to 2019-08-31
  • Centre de recherche en arthrite de l'Université Laval, Subvention, Institutionnel - BDR, BDR - Entités de recherche en émergence, from 2019-01-01 to 2020-01-31
  • Chaire de recherche du Canada sur les maladies rhumatismales auto immunes systémiques, Subvention, Secrétariat des Chaires de recherche du Canada, Chaires de recherche du Canada - Fonctionnement, from 2012-07-01 to 2019-06-30
  • Financement de projet de recherche clinique en rhumatologie, Subvention, Fondation du CHU de Québec, from 2020-01-06 to 2020-03-31
  • MyArthritisGuide for rheumatoid arthritis will improve patient's activation towards self-care, Subvention, Société canadienne de rhumatologie, from 2018-07-01 to 2020-06-30
  • Platelets and their microparticles: versatile players of inflammation., Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2015-07-01 to 2020-06-30
  • Projet de recherche sur les maladies rhumatismales auto-immunes systémiques , Subvention, Fondation du CHU de Québec, from 2019-07-18 to 2020-03-31
  • Randomized Controlled Trial of an Internet-based Scleroderma Self-Management Program: A Scleroderma Patient-Centered Intervention Network (SPIN) Study, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2016-07-01 to 2019-06-30
  • Support informatique (navigateur interactif en ligne) pour les patients souffrant d'arthrite rhumatoïde , Subvention, Fondation du CHU de Québec, from 2019-05-14 to 2020-03-31
Data provided by the Université Laval research projects registery