Dr. Paul R. Fortin, MD, MPH, FRCPC holds the Tier 1 Canada Research Chair in Systemic Autoimmune Rheumatic Diseases, is Professor at Laval University, and Clinical Investigator at the CHU Research Center of Quebec – Laval University. He obtained his medical degree from Laval University and is a graduate of McGill University in rheumatology. He then obtained a Master’s in Public Health from Harvard University’s School of Public Health.

Dr. Fortin is working to better understand the bio-psycho-social impact of systemic autoimmune rheumatic diseases (SARD), such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis, inflammatory myositis, and antiphospholipid syndrome (APS). He is particularly interested in the development of interventions for the treatment of SLE, RA, and APS.

His methodological interests are the development and validation of diagnostic and prognostic tests, new treatments, and new ways to measure the impact of these treatments on the health status of the patient, and on the levels of activity or harm of the disease within SARDs. His other methodological interests include developing healthy lifestyle habits for people with SARD, and measuring the impact of patient knowledge.

Since 2011, Dr. Fortin has been working on the creation and establishment of a new computerized database and biobank that enables the collection of informative biospecimens and clinical data relevant to the study of SARDs. This biobank and database now has more than 13,000 biospecimens, from over 250 people, and has already contributed to translational and clinical research projects, as well as two projects funded by the Canadian Institutes of Health Research.

Dr. Fortin received the Canadian Rheumatology Association (CRA) Young Investigator Award in 1999, the Kirkland Scholar Award in 2008, and the prestigious Research Achievement Award from The Arthritis Society of Canada (2007- 2012). In 2010, he received the Lupus Ontario Hope Award for his outstanding leadership in improving the lives of people with lupus. In May 2015, he received the Jeffrey Shiroky Research Award for his clinical research achievements in rheumatology.

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326 entries « 1 of 33 »

Chew C, Reynolds JA, Lertratanakul A, Wu P, Urowitz M, Gladman DD, Fortin PR, Bae SC, Gordon C, Clarke AE, Bernatsky S, Hanly JG, Isenberg D, Rahman A, Sanchez-Guerrero J, Romero-Diaz J, Merrill J, Wallace D, Ginzler E, Khamashta M, Nived O, Jonsen A, Steinsson K, Manzi S, Kalunian K, Dooley MA, Petri M, Aranow C, van Vollenhoven R, Stoll T, Alarcon GS, Lim SS, Ruiz-Irastorza G, Peschken CA, Askanase AD, Kamen DL, Inanc M, Ramsey-Goldman R, Bruce IN

Lower vitamin D is associated with metabolic syndrome and insulin resistance in systemic lupus: data from an international inception cohort.

Journal Article

Rheumatology (Oxford), 2021, ISSN: 1462-0324.

Abstract | Links:

Mai L, Asaduzzaman A, Noamani B, Fortin PR, Gladman DD, Touma Z, Urowitz MB, Wither J

The baseline interferon signature predicts disease severity over the subsequent 5 years in systemic lupus erythematosus.

Journal Article

Arthritis Res Ther, 23 (1), pp. 29, 2021, ISSN: 1478-6354.

Abstract | Links:

Almeida-Brasil CC, Pineau CA, Vinet E, Hanly JG, Peschken CA, Clarke AE, Fortin PR, Abrahamowicz M, Bernatsky S

Predictors of unsuccessful hydroxychloroquine tapering and discontinuation: Can we personalize decision-making in systemic lupus treatment?

Journal Article

Arthritis Care Res (Hoboken), 2020.

Abstract | Links:

Fortin PR, Da Costa D, Neville C, Julien AS, Rahme E, Haroun V, Singer W, Nimigon-Young J, Morrison AL, Eng D, Peschken CA, Vinet E, Hudson M, Smith D, Matsos M, Pope JE, Clarke AE, Keeling S, Avina-Zubieta JA, Rochon M

The Challenges of Perceived Self-Management in Lupus.

Journal Article

Arthritis Care Res (Hoboken), 2020.

Abstract | Links:

Melki I, Allaeys I, Tessandier N, Mailhot B, Cloutier N, Campbell RA, Rowley JW, Salem D, Zufferey A, Laroche A, Levesque T, Patey N, Rauch J, Lood C, Droit A, McKenzie SE, Machlus KR, Rondina MT, Lacroix S, Fortin PR, Boilard E

FcγRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus.

Journal Article

Blood, 136 (25), pp. 2933-2945, 2020, ISSN: 0006-4971.

Abstract | Links:

Legge A, Kirkland S, Rockwood K, Andreou P, Bae SC, Gordon C, Romero-Diaz J, Sanchez-Guerrero J, Wallace DJ, Bernatsky S, Clarke AE, Merrill JT, Ginzler EM, Fortin PR, Gladman DD, Urowitz MB, Bruce IN, Isenberg DA, Rahman A, Alarcon GS, Petri M, Khamashta MA, Dooley MA, Ramsey-Goldman R, Manzi S, Zoma AA, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, van Vollenhoven RF, Jonsen A, Nived O, Ramos-Casals M, Kamen DL, Kalunian KC, Jacobsen S, Peschken CA, Askanase A, Hanly JG

Prediction of hospitalizations in systemic lupus erythematosus using the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI).

Journal Article

Arthritis Care Res (Hoboken), 2020.

Abstract | Links:

Huot S, Laflamme C, Fortin PR, Boilard E, Pouliot M

IgG-aggregates rapidly upregulate FcgRI expression at the surface of human neutrophils in a FcgRII-dependent fashion: A crucial role for FcgRI in the generation of reactive oxygen species.

Journal Article

FASEB J, 34 (11), pp. 15208-15221, 2020, ISSN: 0892-6638.

Abstract | Links:

Becker YL, Julien AS, Godbout A, Boilard E, Fortin PR

Pilot study of anti-mitochondrial antibodies in antiphospholipid syndrome.

Journal Article

Lupus, 29 (12), pp. 1623-1629, 2020, ISSN: 0961-2033.

Abstract | Links:

Sevim E, Zisa D, Andrade D, Sciascia S, Pengo V, Tektonidou MG, Ugarte A, Gerosa M, Belmont HM, Aguirre Zamorano MA, Fortin PR, Ji L, Efthymiou M, Cohen H, Branch DW, de Jesus GR, Andreoli L, Petri M, Rodriguez E, Cervera R, Knight JS, Atsumi T, Willis R, Roubey R, Bertolaccini ML, Erkan D, Barbhaiya M, APS ACTION Investigators

Characteristics of Antiphospholipid Antibody Positive Patients in AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking.

Journal Article

Arthritis Care Res (Hoboken), 2020.

Abstract | Links:

Bernatsky S, Ramsey-Goldman R, Urowitz MB, Hanly JG, Gordon C, Petri MA, Ginzler EM, Wallace DJ, Bae SC, Romero-Diaz J, Dooley MA, Peschken CA, Isenberg DA, Rahman A, Manzi S, Jacobsen S, Lim SS, van Vollenhoven R, Nived O, Kamen DL, Aranow C, Ruiz-Irastorza G, Sanchez-Guerrero J, Gladman DD, Fortin PR, Alarcon GS, Merrill JT, Kalunian KC, Ramos-Casals M, Steinsson K, Zoma A, Askanase A, Khamashta MA, Bruce I, Inanc M, Clarke AE

Cancer risk in a large inception SLE cohort: Effects of demographics, smoking, and medications.

Journal Article

Arthritis Care Res (Hoboken), 2020.

Abstract | Links:

326 entries « 1 of 33 »
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Active projects

  • Canada research chair in Innovate Systemic Autoimmune Rheumatic Disease, Subvention, Secrétariat des programmes interorganismes à l’intention des établissements, Chaires de recherche du Canada - Fonctionnement, from 2019-07-01 to 2026-06-30
  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Hydroxychloroquine in systemic lupus, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2018-04-01 to 2023-03-31
  • Mapping anti-mitochondrial antibodies in systemic lupus erythematosus, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2022-03-31
  • New statistical methods for cohort studies of adverse effects of medications, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2016-07-01 to 2021-06-30
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2020-04-01 to 2025-03-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, Subvention, La société d'arthrite, from 2020-01-01 to 2022-12-31
  • Projet de recherche sur les maladies arthritiques, Subvention, Fondation de l'Université Laval, from 2019-12-01 to 2021-11-30
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2015-07-01 to 2021-06-30
  • The impact of antimalarial drugs in arthritis patients exposed to SARS-CoV-2- the CoVIRAL project, Subvention, La société d'arthrite, from 2020-04-01 to 2023-03-31
  • Unité support du Québec: Un soutien pour la recherche axée sur le patient., Subvention, Instituts de recherche en santé du Canada, Unités de soutien de la stratégie de recherche axée sur le patient(SRAP), from 2014-04-01 to 2022-03-31

Recently finished projects

  • Canadian Network for Advanced interdisciplinary Methods for Prospective Studies of Drug Safety and Effectiveness., Subvention, Instituts de recherche en santé du Canada, Subvention d'équipe : Centre de collaboration pour les études prospectives du RIEM, from 2014-09-01 to 2019-08-31
  • Centre de recherche en arthrite de l'Université Laval, Subvention, Institutionnel - BDR, BDR - Entités de recherche en émergence, from 2019-01-01 to 2020-01-31
  • Chaire de recherche du Canada sur les maladies rhumatismales auto immunes systémiques, Subvention, Secrétariat des Chaires de recherche du Canada, Chaires de recherche du Canada - Fonctionnement, from 2012-07-01 to 2019-06-30
  • Financement de projet de recherche clinique en rhumatologie, Subvention, Fondation du CHU de Québec, from 2020-01-06 to 2020-03-31
  • MyArthritisGuide for rheumatoid arthritis will improve patient's activation towards self-care, Subvention, Société canadienne de rhumatologie, from 2018-07-01 to 2020-06-30
  • Platelets and their microparticles: versatile players of inflammation., Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2015-07-01 to 2020-06-30
  • Projet de recherche sur les maladies rhumatismales auto-immunes systémiques , Subvention, Fondation du CHU de Québec, from 2019-07-18 to 2020-03-31
  • Randomized Controlled Trial of an Internet-based Scleroderma Self-Management Program: A Scleroderma Patient-Centered Intervention Network (SPIN) Study, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2016-07-01 to 2019-06-30
  • Support informatique (navigateur interactif en ligne) pour les patients souffrant d'arthrite rhumatoïde , Subvention, Fondation du CHU de Québec, from 2019-05-14 to 2020-03-31
Data provided by the Université Laval research projects registery