Dr. Paul R. Fortin, MD, MPH, FRCPC holds the Tier 1 Canada Research Chair in Systemic Autoimmune Rheumatic Diseases, is Professor at Laval University, and Clinical Investigator at the CHU Research Center of Quebec – Laval University. He obtained his medical degree from Laval University and is a graduate of McGill University in rheumatology. He then obtained a Master’s in Public Health from Harvard University’s School of Public Health.

Dr. Fortin is working to better understand the bio-psycho-social impact of systemic autoimmune rheumatic diseases (SARD), such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis, inflammatory myositis, and antiphospholipid syndrome (APS). He is particularly interested in the development of interventions for the treatment of SLE, RA, and APS.

His methodological interests are the development and validation of diagnostic and prognostic tests, new treatments, and new ways to measure the impact of these treatments on the health status of the patient, and on the levels of activity or harm of the disease within SARDs. His other methodological interests include developing healthy lifestyle habits for people with SARD, and measuring the impact of patient knowledge.

Since 2011, Dr. Fortin has been working on the creation and establishment of a new computerized database and biobank that enables the collection of informative biospecimens and clinical data relevant to the study of SARDs. This biobank and database now has more than 13,000 biospecimens, from over 250 people, and has already contributed to translational and clinical research projects, as well as two projects funded by the Canadian Institutes of Health Research.

Dr. Fortin received the Canadian Rheumatology Association (CRA) Young Investigator Award in 1999, the Kirkland Scholar Award in 2008, and the prestigious Research Achievement Award from The Arthritis Society of Canada (2007- 2012). In 2010, he received the Lupus Ontario Hope Award for his outstanding leadership in improving the lives of people with lupus. In May 2015, he received the Jeffrey Shiroky Research Award for his clinical research achievements in rheumatology.

CHUL
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Québec, Québec
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Wirestam L, Enocsson H, Skogh T, Padyukov L, Jonsen A, Urowitz MB, Gladman DD, Romero-Diaz J, Bae SC, Fortin PR, Sanchez-Guerrero J, Clarke AE, Bernatsky S, Gordon C, Hanly JG, Wallace D, Isenberg DA, Rahman A, Merrill J, Ginzler E, Alarcon GS, Chatham WW, Petri M, Khamashta M, Aranow C, Mackay M, Dooley MA, Manzi S, Ramsey-Goldman R, Nived O, Steinsson K, Zoma A, Ruiz-Irastorza G, Lim S, Kalunian K, Inanc M, Vollenhoven RV, Ramos-Casals M, Kamen DL, Jacobsen S, Peschken C, Askanase A, Stoll T, Bruce IN, Wettero J, Sjowall C

Osteopontin and Disease Activity in Patients with Recent-onset Systemic Lupus Erythematosus: Results from the SLICC Inception Cohort.

Journal Article

J Rheumatol, 46 (5), pp. 492-500, 2019, ISSN: 0315-162X.

Abstract | Links:

de Jesus GR, Sciascia S, Andrade D, Nascimento IS, Rosa R, Barbhaiya M, Tektonidou M, Banzato A, Pengo V, Ji L, Meroni PL, Ugarte A, Cohen H, Branch DW, Andreoli L, Belmont HM, Fortin PR, Petri M, Rodriguez E, Cervera R, Knight JS, Atsumi T, Willis R, Erkan D, Levy RA, APS ACTION

Factors associated with first thrombosis in patients presenting with obstetric antiphospholipid syndrome (APS) in the APS Alliance for Clinical Trials and International Networking Clinical Database and Repository: a retrospective study.

Journal Article

BJOG, 126 (5), pp. 656-661, 2019, ISSN: 1470-0328.

Abstract | Links:

Lee J, Pineau CA, Da Costa D, Clarke AE, Fortin PR, Neville C, Neville A, Bernatsky S

Response to Middleton KR et als. Yoga and SLE.

Journal Article

Complement Ther Med, 43 , pp. 311, 2019, ISSN: 0965-2299.

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Becker Y, Loignon RC, Julien AS, Marcoux G, Allaeys I, Levesque T, Rollet-Labelle E, Benk-Fortin H, Cloutier N, Melki I, Eder L, Wagner E, Pelletier M, Hajj HE, Tremblay ME, Belleannee C, Hebert MJ, Dieude M, Rauch J, Fortin PR, Boilard E

Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestations.

Journal Article

Sci Rep, 9 (1), pp. 4530, 2019, ISSN: 2045-2322.

Abstract | Links:

Sciascia S, Willis R, Pengo V, Krilis S, Andrade D, Tektonidou MG, Ugarte A, Chighizola C, Branch DW, Levy RA, Nalli C, Fortin PR, Petri M, Rodriguez E, Rodriguez-Pinto I, Atsumi T, Nascimento I, Rosa R, Banzato A, Erkan D, Cohen H, Efthymiou M, Mackie I, Bertolaccini ML, APS ACTION

The comparison of real world and core laboratory antiphospholipid antibody ELISA results from antiphospholipid syndrome alliance for clinical trials & international networking (APS ACTION) clinical database and repository analysis.

Journal Article

Thromb Res, 175 , pp. 32-36, 2019, ISSN: 0049-3848.

Abstract | Links:

Peschken CA, Wang Y, Abrahamowicz M, Pope J, Silverman E, Sayani A, Iczkovitz S, Ross J, Zummer M, Tucker L, Pineau C, Levy D, Hudson M, Hitchon CA, Huber AM, Smith CD, Avina-Zubieta A, Arbillaga H, Chedeville G, Wynant W, Fortin PR, CaNIOS 1000 Faces Investigators

Persistent Disease Activity Remains a Burden for Patients with Systemic Lupus Erythematosus.

Journal Article

J Rheumatol, 46 (2), pp. 166-175, 2019, ISSN: 0315-162X.

Abstract | Links:

Hanly JG, Li Q, Su L, Urowitz MB, Gordon C, Bae SC, Romero-Diaz J, Sanchez-Guerrero J, Bernatsky S, Clarke AE, Wallace DJ, Isenberg DA, Rahman A, Merrill JT, Fortin PR, Gladman DD, Bruce IN, Petri M, Ginzler EM, Dooley MA, Steinsson K, Ramsey-Goldman R, Zoma AA, Manzi S, Nived O, Jonsen A, Khamashta MA, Alarcon GS, van Vollenhoven RF, Aranow C, Mackay M, Ruiz-Irastorza G, Ramos-Casals M, Sam Lim S, Inanc M, Kalunian KC, Jacobsen S, Peschken CA, Kamen DL, Askanase A, Theriault C, Farewell V

Psychosis in Systemic Lupus Erythematosus: Results From an International Inception Cohort Study.

Journal Article

Arthritis Rheumatol, 71 (2), pp. 281-289, 2019.

Abstract | Links:

Unlu O, Erkan D, Barbhaiya M, Andrade D, Nascimento I, Rosa R, Banzato A, Pengo V, Ugarte A, Gerosa M, Ji L, Efthymiou M, Branch DW, de Jesus GR, Tincani A, Belmont HM, Fortin PR, Petri M, Rodriguez E, Pons-Estel GJ, Knight JS, Atsumi T, Willis R, Zuily S, Tektonidou MG, TheBehalf of APS ACTION

The Impact of Systemic Lupus Erythematosus on the Clinical Phenotype of Antiphospholipid Antibody-Positive Patients: Results From the AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Clinical Database and Repository.

Journal Article

Arthritis Care Res (Hoboken), 71 (1), pp. 134-141, 2019.

Abstract | Links:

Mendel A, Bernatsky SB, Hanly JG, Urowitz MB, Clarke AE, Romero-Diaz J, Gordon C, Bae SC, Wallace DJ, Merrill JT, Buyon JP, Isenberg DA, Rahman A, Ginzler EM, Petri M, Dooley MA, Fortin PR, Gladman DD, Steinsson K, Ramsey-Goldman R, Khamashta MA, Aranow C, Mackay M, Alarcon GS, Manzi S, Nived O, Jonsen A, Zoma AA, van Vollenhoven RF, Ramos-Casals M, Ruiz-Irastorza G, Lim S, Kalunian KC, Inanc M, Kamen DL, Peschken CA, Jacobsen S, Askanase A, Sanchez-Guerrero J, Bruce IN, Costedoat-Chalumeau N, Vinet E

Low aspirin use and high prevalence of pre-eclampsia risk factors among pregnant women in a multinational SLE inception cohort.

Journal Article

Ann Rheum Dis, 2018, ISSN: 0003-4967.

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Fox RS, Kwakkenbos L, Carrier ME, Mills SD, Gholizadeh S, Jewett LR, Roesch SC, Merz EL, Assassi S, Furst DE, Gottesman K, Mayes MD, Thombs BD, Malcarne VL, SPIN Investigators

Reliability and Validity of Three Versions of the Brief Fear of Negative Evaluation Scale in Patients With Systemic Sclerosis: A Scleroderma Patient-Centered Intervention Network Cohort Study.

Journal Article

Arthritis Care Res (Hoboken), 70 (11), pp. 1646-1652, 2018.

Abstract | Links:

302 entries « 1 of 31 »
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Active projects

  • Canadian Network for Advanced interdisciplinary Methods for Prospective Studies of Drug Safety and Effectiveness., Subvention, Instituts de recherche en santé du Canada, Subvention d'équipe : Centre de collaboration pour les études prospectives du RIEM, from 2014-09-01 to 2019-08-31
  • Centre de recherche en arthrite de l'Université Laval, Subvention, Institutionnel - BDR, BDR - Entités de recherche en émergence, from 2019-01-01 to 2020-01-31
  • Centre hospitalier universitaire de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Chaire de recherche du Canada sur les maladies rhumatismales auto immunes systémiques, Subvention, Secrétariat des Chaires de recherche du Canada, Chaires de recherche du Canada - Fonctionnement, from 2012-07-01 to 2019-06-30
  • New statistical methods for cohort studies of adverse effects of medications, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2016-07-01 to 2021-06-30
  • Platelets and their microparticles: versatile players of inflammation., Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2015-07-01 to 2020-06-30
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2015-07-01 to 2020-06-30
  • Unité support du Québec: Un soutien pour la recherche axée sur le patient., Subvention, Instituts de recherche en santé du Canada, Unités de soutien de la stratégie de recherche axée sur le patient(SRAP), from 2014-04-01 to 2022-03-31

Recently finished projects

  • An international multi-center prospective, inception cohort study of neuropsychiatric systemic lupus erythematosus (NPSLE), Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2008-03-31 to 2018-03-31
  • Analyse du profil de cytokines par les cellules sanguines de patients atteints de maladies auto-inflammatoires orphelines, Subvention, Le Grand Défi Pierre Lavoie, Subvention pour projet de recherche sur une maladie héréditaire orpheline, from 2016-10-01 to 2017-09-30
  • Dissemination of the Lupus Interactive Navigator - Measuring its uptake and impact on global health and self-care, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement: Des connaissances à la pratique, from 2016-04-01 to 2018-05-31
  • Journée sur les collagénoses et vasculites, Subvention, Fondation du CHU de Québec, from 2017-05-03 to 2018-03-31
  • Programme de soutien aux chercheurs chevronnés de la Faculté de médecine, Subvention, Université Laval - Soutien à la recherche, Fonds de soutien aux professeurs-chercheurs bénéficiant d’une Chaire de recherche du Canada, from 2016-09-01 to 2018-08-31
  • Randomized Controlled Trial of an Internet-based Exercise Program to Improve Hand Function in Patients with Scleroderma: A Scleroderma Patient-Centered Intervention Network (SPIN) Study, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2016-07-01 to 2017-06-30
  • Soutien à la recherche de Dre Renée-Claude Loignon (fonds 4481), Subvention, Fondation de l'Université Laval, from 2016-10-01 to 2017-09-30
  • The Lupus prEGnAnCY (LEGACY) Cohort, Subvention, Instituts de recherche en santé du Canada, Programme de subvention Catalyseur, from 2017-03-01 to 2018-02-28
Data provided by the Université Laval research projects registery