Dr. Le Sage is an emergency physician and clinical researcher at the Centre Hospitalier Universitaire de Québec. She is also an associate professor and EM Research Director at the Département de médecine familiale et médecine d’urgence at the Laval University School of Medicine. Her research work focusses on emergency and trauma medicine.

Her main interest is concussions (mild Traumatic Brain Injuries) and the prognosis factors that could predict long-term persistent symptoms after such trauma. Her research program – PoCS Research Program – aims to develop clinical decision rules for clinicians who treat these patients, including the possibility of using biomarkers. The latest Canadian multicentre project in its program aims to validate one of its rules for the early detection of persistent symptoms.

Her research also intends to guide emergency physicians regarding the transfer of major trauma patients within the trauma system. Hence her province-wide Delphi survey to develop a consensus on this issue. The validation of these transfer indicators is ongoing.

Dr. Le Sage has been practicing as an emergency physician for more than 30 years and holds a Ph.D. in epidemiology. Her dual expertise allows her to perform serious work on these issues, and to properly disseminate the resulting information to clinicians.

In addition, she has been a member of the Program Committee of Emergency Medicine for over 15 years, and continues to be involved in the development of research in the Département de médecine familiale et médecine d’urgence at the Laval University School of Medicine, particularly for the development of a research program in emergency medicine. She has also been a member of the Clinician Scientist Program of the Royal College of Physicians and Surgeons of Canada at Laval University.

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Thiruganasambandamoorthy V, Yan JW, Rowe BH, Mercier É, Le Sage N, Hegdekar M, Finlayson A, Huang P, Mohammad H, Mukarram M, Nguyen PAI, Syed S, McRae AD, Nemnom MJ, Taljaard M, Silviotti M

Personalised risk prediction following emergency department assessment for syncope.

Journal Article

Emerg Med J, 2021.

Abstract | Links:

Silverberg ND, Iverson GL, Arciniegas DB, Bayley MT, Bazarian JJ, Bell KR, Broglio SP, Cifu D, Davis GA, Dvorak J, Echemendia RJ, Gioia GA, Giza CC, Hinds SR, Katz DI, Kurowski BG, Leddy JJ, Le Sage N, Lumba-Brown A, Maas AIR, Manley GT, McCrea M, McCrory P, Menon DK, Putukian M, Suskauer SJ, van der Naalt J, Walker WC, Yeates KO, Zafonte R, Zasler N, Zemek R, Brown J, Cogan A, Dams-O'Connor K, Delmonico R, Park Graf MJ, Iaccarino MA, Kajankova M, Kamins J, McCulloch KL, McKinney G, Nagele D, Panenka WJ, Rabinowitz AR, Reed N, Wethe JV, Whitehair V

Expert Panel Survey to Update the American Congress of Rehabilitation Medicine Definition of Mild Traumatic Brain Injury.

Journal Article

Arch Phys Med Rehabil, 102 (1), 2021.

Abstract | Links:

Beauchamp F, Boucher V, Neveu X, Ouellet V, Archambault P, Berthelot S, Chauny JM, de Guise E, Émond M, Frenette J, Lang E, Lee J, Mercier É, Moore L, Ouellet MC, Perry J, Le Sage N

Post-concussion symptoms in sports-related mild traumatic brain injury compared to non-sports-related mild traumatic brain injury.

Journal Article

CJEM, 23 (2), 2021.

Abstract | Links:

Lagacé-Legendre C, Boucher V, Robert S, Tardif PA, Ouellet MC, de Guise E, Boulard G, Frémont P, Émond M, Moore L, Le Sage N

Persistent Postconcussion Symptoms: An Expert Consensus-Based Definition Using the Delphi Method.

Journal Article

J Head Trauma Rehabil, 36 (2), 2021.

Abstract | Links:

Blais Lécuyer J, Mercier É, Tardif PA, Archambault PM, Chauny JM, Frenette J, Perry J, Stiell I, Émond M, Lee J, Lang E, Boucher V, Berthelot S, McRae A, Le Sage N

S100B protein level for the detection of clinically significant intracranial haemorrhage in patients with mild traumatic brain injury: a subanalysis of a prospective cohort study.

Journal Article

Emerg Med J, 38 (4), 2021.

Abstract | Links:

Yadav K, Boucher V, Le Sage N, Malo C, Mercier É, Voyer P, Clément J, Émond M

A Delphi study to identify prehospital and emergency department trauma care modifiers for older adults.

Journal Article

Can J Surg, 64 (3), 2021.

Abstract | Links:

Thiruganasambandamoorthy V, Sivilotti MLA, Le Sage N, Yan JW, Huang P, Hegdekar M, Mercier E, Mukarram M, Nemnom MJ, McRae AD, Rowe BH, Stiell IG, Wells GA, Krahn AD, Taljaard M

Multicenter Emergency Department Validation of the Canadian Syncope Risk Score.

Journal Article

JAMA Intern Med, 180 (5), 2020.

Abstract | Links:

Ghandour EK, Lelaidier Hould L, Fortier FA, Gélinas V, Melnick ER, Hess EP, Lang ES, Gravel J, Perry JJ, Le Sage N, Truchon C, LeBlanc A, Dubrovsky AS, Gagnon MP, Ouellet MC, Gagnon I, McKenna S, Légaré F, Sauvé L, van de Belt TH, Kavanagh É, Paquette L, Verrette AC, Plante P, Riopelle RJ, Archambault PM

Adapting two American Decision Aids for Mild Traumatic Brain Injury to the Canadian Context Using the Nominal Group Technique.

Journal Article

Patient, 13 (6), 2020.

Abstract | Links:

Gariepy M, Gravel J, Legare F, Melnick ER, Hess EP, Witteman HO, Lelaidier-Hould L, Truchon C, Sauve L, Plante P, Le Sage N, Archambault PM

Head CT overuse in children with a mild traumatic brain injury within two Canadian emergency departments.

Journal Article

Paediatr Child Health, 25 (1), 2020.

Abstract | Links:

Gariépy M, Gravel J, Légaré F, Melnick ER, Hess EP, Witteman HO, Lelaidier-Hould L, Truchon C, Sauvé L, Plante P, Le Sage N, Archambault PM

Head CT overuse in children with a mild traumatic brain injury within two Canadian emergency departments

Journal Article

Paediatr Child Health, 25 (1), 2020.

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Research field

  • Trauma – Emergency Medicine – mTBI (concussion)

Research theme(s)

  • Clinical research and treatment protocols
  • Organizational assessment of trauma and emergency systems

Research interests

  • Trauma and emergency medicine
  • Quality of care evaluation protocols
  • Development and validation of clinical prediction rules
  • Injury surveillance and prevention

Active projects

  • La protéine S100B est-elle un outil de dépistage valide pour réduire le nombre de tomodensitométries inutiles suite à un traumatisme cranio-cérébral léger?, from 2017-04-01 to 2022-01-31

Recently finished projects

  • Connecting Emergency Departments with Community services to prevent mobility losses in pre-frail & frail Seniors (CEDeComS), from 2016-07-01 to 2020-06-30
  • Établissement d'une liste de soins urgents et spécialisés en traumatologie pour lesquels les patients devraient être dirigés directement vers un centre désigné de traumatologie à l'aide de la méthode Delphi modifiée, from 2019-05-01 to 2021-04-30
  • Santé mentale après un traumatisme craniocérébral chez les personnes âgées et leurs proches aidants., from 2017-04-01 to 2020-05-31
  • Système canadien hospitalier d'information sur la recherche en prévention des traumatismes (SCHIRPT), from 2014-04-01 to 2021-03-31
  • Validation of the canadian syncope and the canadian syncope arrhytmia risk scores., from 2016-08-02 to 2020-03-31
Data provided by the Université Laval research projects registery