Bio

Dr. Plante obtained her medical degree from Laval University in 1985 and completed her residency in obstetrics and gynecology at McGill University in 1990. She continued with a 3-year subspecialty in gynecologic oncology at the Memorial Sloan-Kettering Cancer Center in New York in 1993. Since then, she has worked as a gynecologist-oncologist at l’Hôtel-Dieu de Québec.

Dr. Plante is a Professor in the Department of Obstetrics and Gynecology at Laval University. She is head of the oncology-gynecology department and in charge of clinical research at l’Hôtel-Dieu de Québec.

Expertise

  1. Plante is best known for her expertise in minimally invasive surgery in the treatment of gynecological cancers, including robot-assisted surgery, the sentinel lymph node technique in gynecological cancers and in surgeries aimed at preserving fertility in young women suffering from cervical cancer, including radical trachelectomy.
  2. Plante is the principal investigator of a large international, prospective and randomized study led by the Canadian Cancer Trials Group (CCTG) and the Gynecologic Cancer InterGroup (GCIG) (CX-5 or SHAPE study). The study aims to randomize patients with early-stage and low-risk cervical cancer to receive either radical hysterectomy (standard) or simple hysterectomy (studied). More than 700 patients will be randomized in this study.
  3. In addition, Dr. Plante is particularly interested in oncogenetics related to ovarian cancer. She has been involved in the activities of the oncogenetics department, along with the St-Sacrement Hospital team, since its inception, and is responsible for its ovarian component.

Recent Appointments

  1. Co-chair of CCRN (Cervical Cancer Research Network)
  2. Chair, International Committee, SGO (Society of Gynecologic Oncology)
  3. Co-chair, Cervix Working Group, CCTG
  4. Member, Editorial Board, International Journal of Gynecologic Cancer (IJGC) and Journal of Obstetrics and Gynecology of Canada (JOGC)
L'Hôtel-Dieu de Québec
11, côte du Palais
Québec, Québec
Canada G1R 2J6

Latest news

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155 entries « 3 of 16 »

Sheta R, Wang ZQ, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Macdonald E, Vanderhyden B, Bachvarov D

Hic-5 regulates epithelial to mesenchymal transition in ovarian cancer cells in a TGFβ1-independent manner.

Journal Article

Oncotarget, 8 (47), pp. 82506-82530, 2017, ISSN: 1949-2553.

Abstract | Links:

Viau M, Plante M, Renaud MC, Grondin K, Morin C

Proposed novel nomenclature of vulvar smooth muscle tumors; a case of Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) of the vulva.

Journal Article

Gynecol Oncol Rep, 20 , pp. 1-3, 2017, ISSN: 2352-5789.

Abstract | Links:

Faddaoui A, Sheta R, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Ghani K, Bachvarov D

Suppression of the grainyhead transcription factor 2 gene (GRHL2) inhibits the proliferation, migration, invasion and mediates cell cycle arrest of ovarian cancer cells.

Journal Article

Cell Cycle, 16 (7), pp. 693-706, 2017, ISSN: 1538-4101.

Abstract | Links:

Bernard S, Moffet H, Plante M, Ouellet MP, Leblond J, Dumoulin C

Pelvic-Floor Properties in Women Reporting Urinary Incontinence After Surgery and Radiotherapy for Endometrial Cancer.

Journal Article

Phys Ther, 97 (4), pp. 438-448, 2017, ISSN: 0031-9023.

Abstract | Links:

Atri M, Zhang Z, Dehdashti F, Lee SI, Marques H, Ali S, Koh WJ, Mannel RS, DiSilvestro P, King SA, Pearl M, Zhou X, Plante M, Moxley KM, Gold M

Utility of PET/CT to Evaluate Retroperitoneal Lymph Node Metastasis in High-Risk Endometrial Cancer: Results of ACRIN 6671/GOG 0233 Trial.

Journal Article

Radiology, 283 (2), pp. 450-459, 2017, ISSN: 0033-8419.

Abstract | Links:

Plante M, Renaud MC, Sebastianelli A, Gregoire J

Simple Vaginal Trachelectomy: A Valuable Fertility-Preserving Option in Early-Stage Cervical Cancer.

Journal Article

Int J Gynecol Cancer, 27 (5), pp. 1021-1027, 2017, ISSN: 1048-891X.

Abstract | Links:

Plante M, Stanleigh J, Renaud MC, Sebastianelli A, Grondin K, Gregoire J

Isolated tumor cells identified by sentinel lymph node mapping in endometrial cancer: Does adjuvant treatment matter?

Journal Article

Gynecol Oncol, 146 (2), pp. 240-246, 2017, ISSN: 0090-8258.

Abstract | Links:

Viau M, Renaud MC, Gregoire J, Sebastianelli A, Plante M

Paraneoplastic syndromes associated with gynecological cancers: A systematic review.

Journal Article

Gynecol Oncol, 146 (3), pp. 661-671, 2017, ISSN: 0090-8258.

Abstract | Links:

Touhami O, Gregoire J, Renaud MC, Sebastianelli A, Plante M

Performance of sentinel lymph node (SLN) mapping in high-risk endometrial cancer.

Journal Article

Gynecol Oncol, 147 (3), pp. 549-553, 2017, ISSN: 0090-8258.

Abstract | Links:

Pujade-Lauraine E, Ledermann JA, Selle F, Gebski V, Penson RT, Oza AM, Korach J, Huzarski T, Poveda A, Pignata S, Friedlander M, Colombo N, Harter P, Fujiwara K, Ray-Coquard I, Banerjee S, Liu J, Lowe ES, Bloomfield R, Pautier P, SOLO2/ENGOT-Ov21 investigators

Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial.

Journal Article

Lancet Oncol, 18 (9), pp. 1274-1284, 2017, ISSN: 1470-2045.

Abstract | Links:

155 entries « 3 of 16 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2022-06-13

Recently finished projects

  • Randomized trial comparing radical hysterectomy and pelvic node dissection vs simple hysterectomy and pelvic node dissection in patients with low risk cervical cancer defined as lesions measuring less than 2 cm with less than 50% stromal in, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2012-03-31 to 2020-03-31
Data provided by the Université Laval research projects registery